Neurodegenerative Diseases News and Research

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Tankyrase protein plays an important role in helping drive bowel cancer

The inner workings of the main protein involved in an extensive range of cellular processes have been disclosed by researchers. This possibly sets the stage for improved and less toxic cancer drugs.

25 Nov 2022

Revitalized immune cells improve waste removal from the brain

Damaged protein clusters in the brain are a hallmark of many neurodegenerative diseases, including Parkinson’s, Alzheimer’s, and others. Although they have made significant efforts, scientists have only partially succeeded in finding treatments for these conditions by removing these toxic clusters.

11 Nov 2022

Researchers reveal key developmental difference between the brains of modern humans and Neanderthals

AZoLifesciences speaks to Dr. Anneline Pinson and Prof. Dr. Wieland B. Huttner from The Max Planck Institute of Molecular Cell Biology and Genetics about their latest research which found a greater neuron production in the frontal lobe during brain development in modern humans than Neanderthals, due to the change of a single amino acid in the protein TKTL1.

From The Max Planck Institute 20 Sep 2022

Researchers analyze how clusters of molecules meet inside cells

A developing area studies how clusters of molecules gather inside of cells, similar to how oil droplets form and separate from the water in a vinaigrette.

From New York University (NYU) 15 Sep 2022

Simple blood test helps identify patients developing neurotoxic side effects

The treatment of various tumors has been transformed by cell-based immunotherapy, often known as CAR-T cell therapy. To target and combat specific forms of leukemia and lymphoma, the treatment employs genetically engineered T cells.

8 Sep 2022

Scientists discover latent stem cells that respond to injury in the central nervous system of mice

Scientists at the Francis Crick Institute have identified a group of latent stem cells that respond to injury in the central nervous system of mice. If a similar type of cell exists in humans, they could offer a new therapeutic approach to treat brain and spinal cord injuries.

23 Aug 2022

Scientists determine the contribution of DNA recombinations to genomic diversity in health and disease

Researchers from Japan’s RIKEN Center for Integrative Medical Sciences, working with colleagues from all over the world, found that recombinations of particular genomic sequences, which are reproduced millions of times in the genome of each human cell, are common in both normal and disease states.

28 Jul 2022

Researchers reveal novel mechanism that links interferon activation and α-synuclein function in neurons

There are no disease-modifying therapies for Parkinson’s disease that can alter the course of the disease.

25 Jul 2022

Researchers create novel human cell line to explore blinding eye disorders

Researchers at the LSU Health New Orleans Neuroscience Center of Excellence have created a novel, experimental human cell line from retinal pigment epithelial cells, under the supervision of Boyd Professor Nicolas Bazan, MD, PhD.

14 Jul 2022

Researchers get funding to develop a vaccine against ALS disease

DZNE and Intravacc B.V., have received a grant from the European Union of € 2.5 million to further create a prototype ALS vaccine.

8 Jul 2022

A novel mechanism shared by mutations in varied genes could help treat neurological diseases

Researchers at Tel Aviv University, led by Prof. Illana Gozes from the Department of Human Molecular Genetics and Biochemistry at the Sackler Faculty of Medicine and the Sagol School of Neuroscience, have unraveled a mechanism shared by mutations in the genes ADNP and SHANK3, which cause autism, schizophrenia, and other conditions.

25 May 2022

Stress helps remove the formation of toxic proteins in dementia

Recently, researchers have discovered a novel method that could help avoid the formation of protein tangles, which are typical in dementia.

12 May 2022

Researchers analyze single-cell DNA sequencing for having a significant role in Alzheimer’s disease

The loss of functional neurons in the brain is a characteristic of Alzheimer’s disease. What, on the other hand, is the source of this loss?

21 Apr 2022

Research associates autophagy and age-related nervous system degradation

The in-built mechanism of recycling dead or poisonous material to preserve the health of human cells is critical to general health.

20 Apr 2022

Zbtb38 removal results in early embryonic death

DNA methylation is a critical epigenetic alteration for mammalian development.

20 Apr 2022

Study shows how peptide inhibitor helps to treat Alzheimer’s and Huntington’s disease

According to the Alzheimer’s Association, around 11% of the population, comprising 65-year old and above—in the United States has been diagnosed with Alzheimer’s disease (AD), the most prevalent form of dementia that causes memory loss and cognitive impairment.

19 Apr 2022

Neurodegenerative Diseases News and Research

Tankyrase protein plays an important role in helping drive bowel cancer

Revitalized immune cells improve waste removal from the brain

Researchers reveal key developmental difference between the brains of modern humans and Neanderthals

Researchers analyze how clusters of molecules meet inside cells

Simple blood test helps identify patients developing neurotoxic side effects

Scientists discover latent stem cells that respond to injury in the central nervous system of mice

Scientists determine the contribution of DNA recombinations to genomic diversity in health and disease

Researchers reveal novel mechanism that links interferon activation and α-synuclein function in neurons

Researchers create novel human cell line to explore blinding eye disorders

Researchers get funding to develop a vaccine against ALS disease

A novel mechanism shared by mutations in varied genes could help treat neurological diseases

Stress helps remove the formation of toxic proteins in dementia

Researchers analyze single-cell DNA sequencing for having a significant role in Alzheimer’s disease

Research associates autophagy and age-related nervous system degradation

Zbtb38 removal results in early embryonic death

Study shows how peptide inhibitor helps to treat Alzheimer’s and Huntington’s disease

Critical signaling pathways in immune cells could reduce Alzheimer’s progression

Researchers discover a mechanism by which the protein DELE1 detects organelle stress

Noncoding DNA mutations prevent the brain from amyotrophic lateral sclerosis

New project receives over $700,000 to study about CHARGE syndrome

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