Neurodegenerative Diseases News and Research

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New project receives over $700,000 to study about CHARGE syndrome

CHARGE syndrome, which affects approximately one in 10,000 newborns worldwide, is associated with neurological and behavioral conditions like intellectual disability, attention deficit disorder, convulsions, and autism.

1 Apr 2022

Understanding how cleaning up bad mitochondria affects stem cell division

Most of us remember enough biology to recall that mitochondria are known as "the powerhouse of the cell." Even that audacious term may downplay the importance of mitochondria and what happens when mitochondria go bad.

1 Apr 2022

Novel protein Atossa regulates cell invasion

Researchers from the Institute of Science and Technology Austria have found a novel protein that stimulates energy generation inside immune cells, allowing them to penetrate more effectively.

24 Mar 2022

Microbial communities with auxotrophs more likely to have increased drug tolerance, study finds

Research from the Francis Crick Institute has revealed a key mechanism which increases tolerance to drugs amongst microbial communities.

22 Mar 2022

Transcriptomic analysis of Alzheimer's patients reveals early organelle dysfunction in astrocytes

An international group of researchers led by the UAB analyzed the genes that are expressed in neurons and astrocytes based on data from 800 individuals and compared what happens in Alzheimer's patients and in people without diagnosed dementia.

21 Mar 2022

Insight into oligodendrocyte cells could lead to new treatments for neurodegenerative diseases

New research may help scientists locate immature cells in the central nervous system that could shed light on the causes of neurodegenerative diseases like multiple sclerosis-;and autoimmune disease that affects the brain and nervous system-;and allow for the development of better therapeutic treatments.

14 Mar 2022

Astrocyte networks are essential for spatial learning and memory formation, study shows

Astrocytes form large networks of interconnected cells in the central nervous system. When these cell-to-cell couplings are disrupted in the brain of adult mice, the animals are no longer able to store spatial information.

9 Mar 2022

Researchers observe cellular rejuvenation therapy securely promoting reverse aging in mice

Researchers at Salk observed no rise in cancer or other health problems in mice treated with an anti-aging regimen at the beginning of their middle age.

8 Mar 2022

Research points to a common thread linking diverse neurodegenerative diseases

Take a cell-deep tour of a brain afflicted with Alzheimer's disease, and you will find minuscule clumps of protein that seem suspicious. Ever since the 1980s, when neuroscientists began identifying these protein tangles, researchers have discovered that other brain diseases have their own tangled-protein signatures.

7 Mar 2022

Protein appears key to the function and survival of brain cells most impacted by glaucoma

A ubiquitous protein called sigma 1 receptor, which is known to protect cells from stress, appears key to the function and survival of the neurons most impacted by glaucoma, scientists report.

2 Mar 2022

Novel molecular pathway shared by ALS and frontotemporal dementia identified

Scientists from two independent research teams have discovered how the mislocalization of a protein, known as TDP-43, alters the genetic instructions for UNC13A, providing a possible therapeutic target that could also have implications in treating amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and other forms of dementia.

1 Mar 2022

MIT researchers create a new cerebrovasculature atlas

While neurons and glial cells are by far the most numerous cells in the brain, many other types of cells play important roles. Among those are cerebrovascular cells, which form the blood vessels that deliver oxygen and other nutrients to the brain.

16 Feb 2022

Healthy sleep pattern alleviates some of the symptoms of Alzheimer’s disease

According to research, the brain’s capacity to clear a protein closely associated with Alzheimer’s disease is tied to the circadian cycle.

14 Feb 2022

In vivo tracking of unlabeled stem cells using sugars

A Johns Hopkins Medicine scientist who spent 30 years figuring out how to put chemical labels into cells to track their movement in living tissues has found that certain self-renewing stem cells have built-in tracers -; made out of sugars -; that can do the job without added chemical "labels" when injected into mouse brains.

8 Feb 2022

Neurodegenerative Diseases News and Research

New project receives over $700,000 to study about CHARGE syndrome

Understanding how cleaning up bad mitochondria affects stem cell division

Novel protein Atossa regulates cell invasion

Microbial communities with auxotrophs more likely to have increased drug tolerance, study finds

Transcriptomic analysis of Alzheimer's patients reveals early organelle dysfunction in astrocytes

Insight into oligodendrocyte cells could lead to new treatments for neurodegenerative diseases

Astrocyte networks are essential for spatial learning and memory formation, study shows

Researchers observe cellular rejuvenation therapy securely promoting reverse aging in mice

Research points to a common thread linking diverse neurodegenerative diseases

Protein appears key to the function and survival of brain cells most impacted by glaucoma

Novel molecular pathway shared by ALS and frontotemporal dementia identified

MIT researchers create a new cerebrovasculature atlas

Healthy sleep pattern alleviates some of the symptoms of Alzheimer’s disease

In vivo tracking of unlabeled stem cells using sugars

Researchers discover a sustainable approach for drug development

Study shows how shuttle proteins safeguard the nuclear pores

Researchers aim to tackle neurodegenerative diseases of the eye and brain

Structural proteomics approaches show promise for treating neurodegenerative diseases

Researchers analyze motor protein movement in neurons

First molecular images of enzyme may help solve the mystery cause of hereditary neurodegenerative diseases

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