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Experts identify proteins that regulate dual processes

According to recent research, the protein UBR7 acts as a histone chaperone and controls histone re-deposition at certain sites at the time of DNA replication.

22 Dec 2021

Novel tool can efficiently map new genome sequences to a "pangenome"

Since the first sequencing of the human genome more than 20 years ago, the study of human genomes has relied almost exclusively on a single reference genome to which others are compared to identify genetic variations.

From University of California Santa Cruz 17 Dec 2021

Genetic mutation appears to be a predisposing factor for COPD independent of smoking

In 2019, the WHO positioned chronic obstructive pulmonary disease (COPD) third in the global ranking of causes of death.

From Institut Pasteur 15 Dec 2021

Experts identify subgenome asymmetry at translational level in wheat

Polyploidy is a key route for the creation of new species in plants and a significant means of enhancing agronomic traits in crops.

9 Dec 2021

Scientists test the accuracy of enzymes that copy DNA under weightlessness

Researchers at Queen’s University boarded a modified Falcon 20 aircraft at Ottawa airport on May 22nd, 2019 as part of a scheduled “vomit comet” flight. In this mode of flight, the plane repeatedly climbs in a steep parabola to 8 km, alternating with a freefall descent.

2 Dec 2021

Experts analyze key protein complexes involved in DNA replication and repair

Cryogenic electron microscopy (cryo-EM) allows scientists to investigate the assembly of DNA replication machinery where DNA is damaged.

25 Nov 2021

Study elucidates the role of genomics in obsessive-compulsive disorder

According to recent research carried out by the researchers from the Icahn School of Medicine at Mount Sinai, both rare and commonly seen differences in the DNA letters threaded along an individual’s chromosomes can elucidate about a third of the risk for being diagnosed with obsessive-compulsive disorder (OCD).

19 Nov 2021

Researchers discover a link between genetic variant and chronic hypersensitivity pneumonitis

Chronic hypersensitivity pneumonitis (CHP) is a long-term lung condition where the interstitial tissue surrounding the alveoli (air sacs) of the lungs becomes inflamed and develops "fibrosis", or scar tissue.

17 Nov 2021

CRISPR screening identifies metabolic enzyme as new target for anti-inflammatory therapeutics

A metabolic enzyme that has been studied in cancer biology and is important for T cell function may offer a new target for anti-inflammatory therapeutics, Vanderbilt researchers have discovered.

12 Nov 2021

Scientists use DNA to create what may be the world's tiniest ruler for measuring proteins

As scientists have probed the mysteries of life down to smaller and smaller scales, they have invented tools to help them understand what they observe.

22 Oct 2021

Experts explain left–right asymmetry development in the embryo

Research on the development of symmetry in mice embryos is anticipated to provide a deeper understanding of the causes of disease.

21 Oct 2021

New research center brings advancements in genomic medicine to admixed individuals

One way to make health care more personalized is to use a person's DNA sequence -; or genome -; to predict their risk of disease. But as the field of precision medicine grows, so have concerns that we may be leaving a large fraction of Americans out.

From UC San Diego 13 Oct 2021

Researchers develop key components of an expanded genetic code system

Modern biologists nurture more ambitious goals and one among them is to know how to broaden or alternatively modify the genetic code of life on Earth.

1 Oct 2021

Tumor suppressor protein binding to RNA also binds DNA, says study

Scientists from the Medical University of South Carolina earlier displayed how hnRNP E1 attaches to metastatic-linked RNAs to prevent their translation.

27 Sep 2021

Study identifies C9orf72 repeat expansion using novel genetic marker

Research offers a new genetic tool to pinpoint C9orf72 repeat expansion-carrying frontotemporal lobar degeneration from huge population-based cohorts.

25 Aug 2021

Rare variants in the MX1 gene increase susceptibility to zoonotic H7N9 avian influenza

According to recent research, rare, single-nucleotide variants in the MX1 gene increase the human susceptibility to zoonotic H7N9 avian influenza infection.

23 Aug 2021

Genomic surveillance is vital to achieve effective mitigation and containment of COVID-19

Although the development and increasingly widespread availability of effective and safe vaccines provides the greatest hope for the future recovery from the increasingly devastating COVID-19 pandemic, genomic surveillance is emerging as a vital necessity to achieve effective mitigation and containment.

19 Aug 2021

Novel computational tool facilitates accurate analysis of complex genomes

HudsonAlpha Institute for Biotechnology faculty investigator Josh Clevenger, PhD, in his nearly eight years of working in the peanut breeding and genetics sectors, has become passionate about enhancing crops for more sustainable and robust agriculture.

11 Aug 2021

Researchers discover nucleotide sequences characteristic of microRNA isoforms

Researchers from HSE University have discovered nucleotide sequences characteristic of microRNA isoforms (microRNAs with errors).

22 Jul 2021

New genetic technique shows the relationship between thyroid function and lipid profile

The thyroid gland produces amino acid-based compounds known as thyroid hormones.

12 Jul 2021