Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Protecting normal cells from chemotherapy, while eliminating drug-resistant cancer cells

A new review paper was published in Oncotarget's Volume 14 on March 11, 2023, entitled, "Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells."

14 Mar 2023

Study pinpoints a splicing deregulation that causes therapeutic vulnerability in pediatric AML

Pediatric acute myeloid leukemia or pAML is a childhood blood cancer, one that has proved confounding to clinicians and researchers, with a high relapse rate and relatively few identified genetic mutations (compared to the adult version) that might explain its cause.

8 Mar 2023

Revolutionary drug blocks a gene associated with driving the spread of bone cancer

Researchers at the University of East Anglia have developed a new drug that works against all of the main types of primary bone cancer.

8 Mar 2023

Using nanoparticles to carry drugs across the blood-brain barrier

Brain tumors are notoriously hard to treat. One reason is the challenge posed by the blood-brain barrier, a network of blood vessels and tissue with closely spaced cells.

3 Mar 2023

Uncovering the complete 3D structure of p53 protein

By inducing cell repair or self-destruction, the tumor suppressor protein p53, often known as “the guardian of the genome,” shields the body’s DNA from daily stress or long-term damage.

2 Mar 2023

The relationship between cancer and DMD gene expression discovered

Mutations of the gene encoding dystrophins have long been known to cause the debilitating muscle-wasting disease DMD, which affects one in every 5,000 boys born. People with the condition will usually only live into their 20s or 30s.

28 Feb 2023

Redefining low-risk WNT-pathway medulloblastoma based on newer biological information

A new research perspective was published in Oncotarget's Volume 14 on February 7, 2023, entitled, "WNT-pathway medulloblastoma: what constitutes low-risk and how low can one go?"

28 Feb 2023

Study shows why a specific gene mutation has opposite effects on mice and human cancers

A small but significant metabolic difference between human and mouse lung tumor cells, has been discovered by Weill Cornell Medicine researchers, explaining a discrepancy in previous study results, and pointing toward new strategies for developing cancer treatments.

27 Feb 2023

New model simplifies the understanding of vascular malformations

Our bodies are made up of 60,000 miles of complex pipes that play a vital role in transporting nutrients throughout our bodies, performing waste disposal, and supplying our organs with fresh oxygen and blood.

27 Feb 2023

Insilico Medicine: IND application for first generative AI-designed drug for COVID-19 approved

Insilico Medicine, a clinical-stage biotech company powered by generative AI, today announces that China National Medical Products Administration (NMPA) has approved the Investigational New Drug (IND) application for ISM3312, an orally available 3CLpro inhibitor generated and designed with the support of Insilico's proprietary generative chemistry platform Chemistry42 for the treatment of COVID-19.

24 Feb 2023

Genes can be used to better predict the likelihood of kidney cancer recurrence

A decade-long international study into kidney cancer has shown that doctors can predict the likelihood of a patient's disease returning by looking at DNA mutations in their tumors.

24 Feb 2023

Whole genome sequencing might help better assess tumor evolution

To develop the most efficacious, personalized treatment plans for patients with Hodgkin lymphoma or other cancers, researchers and clinicians must first understand the genetic changes that cause cancer to develop.

23 Feb 2023

UTA professor leads a state-funded project to explore how T-cells detect cancer

A University of Texas at Arlington bioengineering professor is leading a state-funded project that will try to identify what T-cells are detecting in cancerous cells to better craft a personalized cancer immunotherapy.

23 Feb 2023

Monitoring bovine meat and milk factor protein expression could enable colorectal cancer detection

Bovine meat and milk factors (BMMFs)-; initially identified by de Villiers et al. in 2014-; represent a class of infectious agents in beef and cow's milk that have been linked to the development of cancer.

23 Feb 2023

Analyzing the existence of unknown miniproteins

Evolutionarily young miniproteins are unique in humans, and scientists have recently found thousands of them.

21 Feb 2023

Novel metabolic pathway that makes immunology more efficient revealed

The metabolic pathways that produce a specific type of T cell are distinct from previously assumed, according to findings from the University of Michigan Rogel Cancer Center.

21 Feb 2023

Novel approach removes the barriers of lifesaving cancer genetic services

Genetic counseling and genetic testing for mutations in certain genes such as BRCA1 and BRCA2 genes -; can help people understand their risk of certain types of cancer that can run in families, and improve outcomes through prevention, early detection, and targeted treatments.

16 Feb 2023

MD Anderson and Replay launch new company pioneering T cell receptor NK cell therapies

The University of Texas MD Anderson Cancer Center and Replay today announced the launch of Syena, a new oncology-focused product company pioneering T cell receptor (TCR) natural killer (NK) cell therapies.

15 Feb 2023

Robust new method accurately identifies eight antidepressants

In recent years, a mass spectrometry process that can detect the amounts of drugs in a biological sample, such as blood, has become a powerful diagnostic tool for helping medical professionals identify and monitor levels of therapeutic drugs in patients, which can cause unwanted or dangerous side effects.

14 Feb 2023

Complete Genomics Drops Genome Sequencing Price to Sub $100 at AGBT General Meeting

Complete Genomics Inc., a global life science tools leader and subsidiary of MGI Tech Co., Ltd. (“MGI”), today launched new revolutionary products and prices at Advances in Genome Biology and Technology (AGBT) General Meeting.

From Complete Genomics 9 Feb 2023

Oncology News and Research

Protecting normal cells from chemotherapy, while eliminating drug-resistant cancer cells

Study pinpoints a splicing deregulation that causes therapeutic vulnerability in pediatric AML

Revolutionary drug blocks a gene associated with driving the spread of bone cancer

Using nanoparticles to carry drugs across the blood-brain barrier

Uncovering the complete 3D structure of p53 protein

The relationship between cancer and DMD gene expression discovered

Redefining low-risk WNT-pathway medulloblastoma based on newer biological information

Study shows why a specific gene mutation has opposite effects on mice and human cancers

New model simplifies the understanding of vascular malformations

Insilico Medicine: IND application for first generative AI-designed drug for COVID-19 approved

Genes can be used to better predict the likelihood of kidney cancer recurrence

Whole genome sequencing might help better assess tumor evolution

UTA professor leads a state-funded project to explore how T-cells detect cancer

Monitoring bovine meat and milk factor protein expression could enable colorectal cancer detection

Analyzing the existence of unknown miniproteins

Novel metabolic pathway that makes immunology more efficient revealed

Novel approach removes the barriers of lifesaving cancer genetic services

MD Anderson and Replay launch new company pioneering T cell receptor NK cell therapies

Robust new method accurately identifies eight antidepressants

Complete Genomics Drops Genome Sequencing Price to Sub $100 at AGBT General Meeting

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Commercializing Innovation in a Life Sciences Ecosystem

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