Protein Folding News and Research

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Study reveals specialized mechanism for translation of mitochondrial genome into proteins

An international collaboration among researchers from Finland, Sweden, UK and the USA has captured ribosomes translating messenger RNA expressed from the maternally inherited mitochondrial genome.

23 Feb 2021

Study provides insight into the structure of prion proteins responsible for diseases

Prion diseases are a group of rapidly progressive, fatal and infectious neurodegenerative disorders affecting both humans and animals: Bovine Spongiform Encephalopathy (BSE) or 'mad cow' disease is one of the most famous since in 1996 scientists found that the agent responsible for the disease in cows, is the same agent responsible for the so-called variant Creutzfeldt-Jakob Disease (vCJD), a disease affecting humans.

22 Feb 2021

Scientists discover how the 3D structure of eye-lens proteins is formed

The lens of the human eye gets its transparency and refractive power from the fact that certain proteins are densely packed in its cells.

11 Feb 2021

Study describes dynamic link between protein folding and misfolding

Correct, or native, protein folding is essential for correct protein function. Protein misfolding can lead to the formation of amyloid fibrils, and amyloidosis, which is implicated in various human neurodegenerative diseases, including Parkinson's, Alzheimer's, and Huntington's diseases.

From Osaka University 2 Feb 2021

Study shows how AFV3-109 protein with slipknot structure folds and unfolds based on temperature

Scientists from the Pacific Quantum Center of Far Eastern Federal University (FEFU) figured out how the AFV3-109 protein with slipknot structure folds and unfolds depending on temperature. The protein is typical for the viruses of the oldest single-celled organisms that can survive in the extreme conditions of underwater volcanic sources - archaea. The research outcome appears in PLOS ONE.

15 Jan 2021

“Lab-made” proteins have better industrial applicability than natural proteins

Bioengineers have found why proteins that are designed from scratch tend to be more tolerant to high temperatures than proteins found in nature.

14 Dec 2020

Scientists use advanced methods for investigating structure and interactions of proteins

Michael Gross, professor of chemistry in Arts & Sciences at Washington University in St. Louis and of immunology and internal medicine at the School of Medicine, and his team are experts in footprinting proteins -- that is, using advanced methods for investigating the structure and interactions of proteins within larger molecules.

8 Dec 2020

New breakthrough in AI system could significantly accelerate biological research

In a major scientific advance, the latest version of DeepMind's AI system AlphaFold has been recognized as a solution to the 50-year-old grand challenge of protein structure prediction, often referred to as the 'protein folding problem', according to a rigorous independent assessment.

1 Dec 2020