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Study uncovers genomic drivers and therapeutic vulnerabilities of transformed cutaneous T-cell lymphoma

Cutaneous T-cell lymphoma (CTCL) is an incurable, rare cancer of skin-homing T cells that is highly disfiguring and lethal at advanced stages.

2 Mar 2022

Novel molecular pathway shared by ALS and frontotemporal dementia identified

Scientists from two independent research teams have discovered how the mislocalization of a protein, known as TDP-43, alters the genetic instructions for UNC13A, providing a possible therapeutic target that could also have implications in treating amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and other forms of dementia.

1 Mar 2022

Microbes hindering cancer therapy seem to play a bigger role than helpful ones

Melanoma patients receiving therapy that helps their immune system kill cancer cells respond to treatment differently depending on the types of microbes in their gut, and new research suggests the microorganisms hindering therapy have more influence than the beneficial ones.

1 Mar 2022

TGen collaborates with Deepcell to employ AI for analyzing single cell morphology

The Translational Genomics Research Institute, an affiliate of City of Hope, is partnering with a Silicon Valley firm to become one of the first research institutes in the world to employ a new Artificial Intelligence-powered imaging and sorting technology to classify and isolate individual diseased cells.

23 Feb 2022

Researchers elucidate how early embryo cells begin to independently produce proteins

It happens in the first hours after fertilization: The cells of the early embryo begin to independently produce proteins, the building blocks for cells and organs.

16 Feb 2022

Cancer driving protein plays crucial role in the development of lung cancer, study reveals

Lung cancer is the second leading cancer in the United States and the No. 1 cause of cancer-associated deaths.

15 Feb 2022

Experts identify the master regulator of Nodal signaling in human embryonic stem cells

A new study has led to the discovery that the Hippo signaling effector YAP1 is a master controller of Nodal signaling in hESCs for a process crucial to human development.

14 Feb 2022

Intracellular pathogens trick the host’s immune system to evade destruction

A signaling mechanism that enables bacteria like Salmonella to escape destruction by the immune system of the host was discovered by scientists.

From The University of California, Davis 14 Feb 2022

Pro-regenerative metabolite supports elevated tissue regeneration and delays aging, study reveals

Research recognizes uridine as a pro-regenerative metabolite that highlighted human stem cell activity and improved restructuring and tissue repair.

14 Feb 2022

P53 protein induces leader cell behavior, migration and clearance during epithelial tissue repair

New research led by the University of Bristol has found the protein p53 plays a key role in epithelial migration and tissue repair.

11 Feb 2022

Researchers decipher the genome of Steller’s sea cow from fossil bones

During the Ice Age, giant mammals such as mammoths, sabre-toothed cats and woolly rhinoceroses once roamed Northern Europe and America.

9 Feb 2022

Kras oncogenes use genetic reprogramming to drive tumorigenesis

Cancerous tumors are made up of rapidly growing, abnormally shaped, cells that can infiltrate and destroy healthy tissues, travel to other parts of the body, and form additional tumors.

8 Feb 2022

Groundbreaking discovery could lead to the design of novel therapeutics for wound-healing

An international team led by the Case Western Reserve University School of Medicine has discovered novel properties of the protein Gasdermin B that promotes repair of cells lining the gastrointestinal tract in people with chronic inflammatory disorders like Crohn's disease and ulcerative colitis.

8 Feb 2022

Genetic insights offer potential new targets for acne treatment

A study of the genetics of acne has identified 29 regions of the genome that influence the condition. These genetic insights offer potential new targets for treatment. They may also help clinicians identify individuals at high risk of severe disease.

8 Feb 2022

Researchers develop artificial protein muscle that moves independently

Research carried out from the University of Freiburg’s livMatS Cluster of Excellence showed outstanding progress in creating a muscle using only natural proteins.

2 Feb 2022

MIT researchers develop new way to deliver RNA in a capsule

Like most vaccines, RNA vaccines have to be injected, which can be an obstacle for people who fear needles. Now, a team of MIT researchers has developed a way to deliver RNA in a capsule that can be swallowed, which they hope could help make people more receptive to them.

1 Feb 2022

Scientists develop low-cost metagenome sequencing technique for microbiome research

A research team headed by the Chinese Academy of Sciences, QIBEBT developed a low-cost metagenome sequencing technology.

31 Jan 2022

Mother's unhealthy vaginal microbiome may contribute to mortality and altered development in babies

A new study in mice from University of Maryland School of Medicine researchers showed that an unhealthy vaginal microbiome in pregnant mothers in combination with an unhealthy diet contributed to increased pup deaths and altered development in the surviving babies.

28 Jan 2022

Lucky genes linked to lower risk of diseases in people with obesity

Geneticists have revealed why some people with obesity remain relatively healthy, whilst others suffer from life-changing ailments such as type 2 diabetes and heart disease.

From University of Exeter 25 Jan 2022

New 'disease-in-a-dish' system developed to study oculocutaneous albinism

Researchers at the National Eye Institute have developed the first patient-derived stem cell model for studying eye conditions related to oculocutaneous albinism (OCA).

12 Jan 2022

Skin News and Research

Study uncovers genomic drivers and therapeutic vulnerabilities of transformed cutaneous T-cell lymphoma

Novel molecular pathway shared by ALS and frontotemporal dementia identified

Microbes hindering cancer therapy seem to play a bigger role than helpful ones

TGen collaborates with Deepcell to employ AI for analyzing single cell morphology

Researchers elucidate how early embryo cells begin to independently produce proteins

Cancer driving protein plays crucial role in the development of lung cancer, study reveals

Experts identify the master regulator of Nodal signaling in human embryonic stem cells

Intracellular pathogens trick the host’s immune system to evade destruction

Pro-regenerative metabolite supports elevated tissue regeneration and delays aging, study reveals

P53 protein induces leader cell behavior, migration and clearance during epithelial tissue repair

Researchers decipher the genome of Steller’s sea cow from fossil bones

Kras oncogenes use genetic reprogramming to drive tumorigenesis

Groundbreaking discovery could lead to the design of novel therapeutics for wound-healing

Genetic insights offer potential new targets for acne treatment

Researchers develop artificial protein muscle that moves independently

MIT researchers develop new way to deliver RNA in a capsule

Scientists develop low-cost metagenome sequencing technique for microbiome research

Mother's unhealthy vaginal microbiome may contribute to mortality and altered development in babies

Lucky genes linked to lower risk of diseases in people with obesity

New 'disease-in-a-dish' system developed to study oculocutaneous albinism

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