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Study uncovers how CD8+ T cells can divide and produce two distinct daughter cells

An immunological problem has been addressed by scientists at St. Jude Children’s Research Hospital. Despite being genetically identical, a CD8+ T cell can divide and produce two functionally different daughter cells.

27 May 2022

bit.bio launches Huntington’s disease human cell model

First neurodegenerative disease model launched from bit.bio's new ioDisease Model portfolio.

From bit.bio 10 May 2022

Researchers analyze the potential role of mRNA in drug development and novel therapies

In latest years, messenger RNA—the DNA’s close relative in the complex process of turning a string of genetic blueprints into a properly functioning organism—has gotten a lot of attention in the scientific and medical community.

29 Apr 2022

Genetic variations in key mitochondrial enzyme associated with age-related mobility changes

Age-related changes in strength and mobility may depend on genetic variations in a critical mitochondrial enzyme, suggests a study published today in eLife.

27 Apr 2022

Regulatory framework of stem cell-based therapy in China

Clinical researches of stem cell-based therapies are highly active in China, while it was arduous to determine the most effective way of clinical translation of those advanced therapies.

25 Apr 2022

Researchers explore how tRNAs evolve in protein synthesis

In the process of protein synthesis, a peptide bond is formed between two amino acids that are bound to two different transfer RNAs (tRNAs). Researchers have long been perplexed as to how these tRNAs evolved to be so near to one another on the ribosome.

From Tokyo University of Science 22 Apr 2022

Scientists reveal the origins and provide a detailed ID card of pancreatic endocrine stem cells

The pancreas is a key metabolic regulator. When pancreatic beta cells cease producing enough insulin, blood sugar levels rise dangerously — a phenomenon known as hyperglycemia — thus triggering diabetes.

20 Apr 2022

A new rule book for the design of therapeutic cells with improved specificity and safety

Therapies based on engineered immune cells have recently emerged as a promising approach in the treatment of cancer.

18 Apr 2022

Researchers explore a new procedure to disrupt gene regulation

What role does DNA packing play in regulating gene activity? Fanka Rang and Kim de Luca, researchers from Jop Kind’s (group leader at the Hubrecht Institute and Oncode Investigator) group, created a way to monitor both gene activity and DNA packaging at the same time to address this topic.

5 Apr 2022

Lifebit; Making Biomedical Data Accessible

In this interview, we speak to Dr. Maria Chatzou Dunford, CEO of Lifebit, about their technology and how it helps scientists to make better use of their data.

From Lifebit 1 Apr 2022

Novel protein Atossa regulates cell invasion

Researchers from the Institute of Science and Technology Austria have found a novel protein that stimulates energy generation inside immune cells, allowing them to penetrate more effectively.

24 Mar 2022

Protein appears key to the function and survival of brain cells most impacted by glaucoma

A ubiquitous protein called sigma 1 receptor, which is known to protect cells from stress, appears key to the function and survival of the neurons most impacted by glaucoma, scientists report.

2 Mar 2022

Intestinal cell changes are driven by the BMP signaling pathway, study finds

Intestinal cells can change specializations during their lives. The BMP signaling pathway – an important communication mechanism between cells – appears to be the driver of these changes.

2 Mar 2022

Looking at protein activity gives a complete picture of leukemia's weaknesses

Blocking a protein chain reaction makes childhood leukemia cells more sensitive to an existing targeted treatment, a new study shows.

28 Feb 2022

New technique uses microscopic magnetic particles to remotely activate brain cells

Scientists at UCL have developed a new technique that uses microscopic magnetic particles to remotely activate brain cells; researchers say the discovery in rats could potentially lead to the development of a new class of non-invasive therapies for neurological disorders.

From University College London 24 Feb 2022