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Mortality of newborns on ECMO linked with red blood cell transfusion volume

Newborns in respiratory failure who require the life-sustaining support of ECMO also require transfusion of red blood cells. But a new study indicates that the higher volume of these oxygen-carrying blood cells the babies receive, the higher their mortality rate.

15 Feb 2022

Hemoglobin plays role as a chemosensory signal for mother mice to protect offspring

Biochemists in Japan were surprised to discover that the molecule hemoglobin in the blood works not only as an oxygen carrier, but when the blood is spilled as a result of aggression, accident or predator attack, the molecule also acts as a chemosensory signal -; a chemical stimulus picked up by the senses, namely smell in this case -; for lactating mother mice, prompting digging or rearing behavior in them to check the surrounding environment and keep their offspring safe.

11 Feb 2022

Three proteins as potential new therapeutic targets in movement disorders

Three members of a family of proteins have been identified that are important to helping us fine tune the activity of brain chemicals which enable us to walk or stand at will, scientists report.

11 Feb 2022

Cell culture environments are unstable and drive reproducibility crisis

Culture environments of different cell types growing in culture vessels or Petri dishes vary significantly from each other and from conditions in the living body, potentially driving the "reproducibility crisis" in biomedical research, according to a team of KAUST bioscientists.

9 Feb 2022

Microorganisms “breathe” rocks through extracellular electron transfer, says study

Microbes may be tiny, yet they have a significant influence on the Earth’s habitability.

4 Feb 2022

Scientists visualize protein machinery of respiration with unparalleled precision

Oxygen and sugar are the basis of life for animals, plants, fungi and many bacteria. The metabolic process called respiration makes it possible to convert food into energy for the cells.

1 Feb 2022

Study offers insight into how activated protein C may protect aging patients from reperfusion injury

A University of South Florida Health (USF Health) preclinical study offers molecular insight into how activated protein C (APC) may improve aging patients' tolerance to reperfusion injury – a potentially adverse effect of treatment for ischemic heart disease.

1 Feb 2022

Research offers new insight into climate change in the Early Holocene

New insight into how our early ancestors dealt with major shifts in climate is revealed in the research, published today [27 Jan] in Nature Ecology & Evolution, by an international team, led by Professor Rick Schulting from Oxford University's School of Archaeology.

28 Jan 2022

Protecting plants is imperative to sustain the health and wealth, report says

From farms to forests, Canada's plants face increasingly complex threats and protecting them is imperative to sustain the health and wealth they provide, according to Cultivating Diversity, a new expert panel report from the Council of Canadian Academies.

28 Jan 2022

Paving the Way for a New Lab-Grown Meat

In this interview, we speak to Professor Kelly Schultz and colleagues about their latest research that has led to the development of a new lab-grown meat.

From Lehigh University 18 Jan 2022

Using E.Coli to bring 3D Printing to Life

In this interview, we speak to Dr. Avinash Manjula Basavanna about his latest research that incorporated E. Coli to bring 3D printing materials to life.

From Massachusetts Institute of Technology (MIT) 13 Jan 2022

A highly effective protection against oxidative stress developed by present-day humans

Very few proteins in the body have a change that makes them unique compared to the corresponding proteins in Neanderthals and apes. Researchers at the Max Planck Institute for Evolutionary Anthropology in Germany and Karolinska Institute in Sweden have now studied one such protein, glutathione reductase, which protects against oxidative stress.

From The Max Planck Institute 6 Jan 2022

Researchers discover a crucial and exploitable vulnerability in diffuse large B cell lymphomas

Aggressive and relatively common lymphomas called diffuse large B cell lymphomas (DLBCLs) have a critical metabolic vulnerability that can be exploited to trick these cancers into starving themselves, according to a study from researchers at Weill Cornell Medicine and Cornell's Ithaca campus.

4 Jan 2022

Biochemical signals sent from cell to cell play a key role in deciding their fate

Scientists have found a way to prove that biochemical signals sent from cell to cell play an important role in determining how those cells develop.

24 Dec 2021

"Heavy" hydrogen makes drugs to have a longer effect

Hydrogen (abbreviated "H") is the lightest of all elements. It usually consists only of a positively charged proton and a negatively charged electron and is also called protium in this form. But there are also two heavier hydrogen isotopes, deuterium and tritium.

24 Dec 2021

Study uncovers mechanism that triggers cancer cell death

Scientists recently pinpointed the mechanism by which inhibitors of the ERK5 protein kinase diminish cancer cell proliferation and trigger their death.

23 Dec 2021

Tiny microbes belching toxic gas helped cause the biggest mass extinction in Earth's history

Tiny microbes belching toxic gas helped cause -; and prolong -; the biggest mass extinction in Earth's history, a new study suggests.

21 Dec 2021

Protein protects against heart damage following cancer treatment

Cancer treatment is hard on the body, however for the patient to endure cancer, it is mostly necessary to undergo the treatment.

17 Dec 2021

Developing a New Method to Detect Food Fraud

In this interview, we speak to Florian Cueni about his latest research that developed a new method to detect food fraud.

14 Dec 2021

Study develops robust imaging technique to measure in situ oxygen concentration

The advancements in technology might come up with techniques that measure biological parameters in real-time in living organisms, which can help monitor tissue homeostasis, on the go. A significant component of such homeostasis is tissue oxygen concentration.

25 Nov 2021