Unchained Labs’ Hound is the only tool that merges microscopy, Raman spectroscopy, and laser-induced breakdown spectroscopy (LIBS) for users to characterize particles by size, count and shape, and identify particles by their elemental or chemical fingerprints.
Equipped with all these capabilities in a single instrument, the Hound collects all the information that users would need about their particles, in just a few minutes.
- Shape
- Size
- Count
- Elemental ID
- Chemical ID

Key Applications
- Distinguish protein aggregates from formulation components or contaminants
- Visible and subvisible particle counting and identification
- Particle characterization in wet samples or powder dispersions
- Particle characterization by size and morphology
- Root cause analysis and identification of contaminants or unknown particles
- Identify particles by Raman and/or laser-induced breakdown spectroscopy (LIBS)
Key Features
- 532 nm Raman, 785 nm Raman, and LIBS in a single instrument
- Up to 50X microscopic imaging in bright and dark field
- Image capture at 5.1 megapixels
- Measures particles between 2 microns and 15 mm
- Identifies particles by Raman as small as 2 microns
- Identifies particles by LIBS as small as 20 microns
- Size and/or morphology-directed particle identification
- Manual or automated operational modes
- Up to 4 samples analyzed in an automated experiment
- Gold-coated filters and glass surfaces, which improve signal/noise and are Raman inactive
- Guided software for manual or automated particle identification with Raman and/or LIBS
- User-defined, transferrable experimental methods to store and share experiment parameters
- Built-in data integrity checks with experiment, method, database, and report file validations
- 21 CFR part 11 compliance tools included
- Preloaded with 532 nm Raman, 785 nm Raman, and LIBS spectral information for 200+ common particles
- Expandable and customizable spectral reference library to refine identifications