Analytical Chemistry in Life Sciences - New Single-Cell Technique Reveals Why Bacteria Survive Antibiotics
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Predict in vivo bioequivalence with greater accuracyPredict in vivo bioequivalence with greater accuracy

Developing generic drugs requires proving bioequivalence, but standard dissolution tests often miss absorption changes from excipients. Pion’s BioFLUX™ and miniFLUX™ systems measure both simultaneously, revealing excipient effects, flagging high-risk formulations early, and improving alignment with in vivo and regulatory expectations—helping reduce risk and speed development.

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   New Single-Cell Technique Reveals Why Bacteria Survive AntibioticsNew Single-Cell Technique Reveals Why Bacteria Survive Antibiotics
 
SinBactM's innovative approach to single-bacterium metabolomics reveals distinct metabolic states, enhancing understanding of antibiotic resistance in bacteria.
 
   Glucose acts as a metabolic signal for myelin developmentGlucose acts as a metabolic signal for myelin development
 
Researchers at the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) have uncovered a surprising link between low brain sugar levels and the development of myelin - the protective coating that allows nerve cells to communicate rapidly and efficiently.
 
 Tumor splicing burden predicts treatment response in kidney cancer
 
Tumor splicing burden predicts treatment response in kidney cancerResearchers at City of Hope® and TGen (part of City of Hope) have identified a significant correlation between a tumor's "splicing burden" and its clinical response to treatment for metastatic renal cell carcinoma (mRCC).
 
 
 Identifying the ages when Alzheimer’s biomarkers sharply change
 
Identifying the ages when Alzheimer’s biomarkers sharply changeNew research identifies critical ages for Alzheimer's biomarkers, enhancing screening strategies and understanding neurodegeneration across the aging spectrum.
 
 
 New genomic study tracks rare blood disease in children
 
New genomic study tracks rare blood disease in childrenAplastic anemia is a rare, life-threatening blood disorder where patients are unable to make enough blood cells due to the immune system's attack on blood stem cells. The condition can progress to myelodysplastic syndrome (MDS) and leukemia. A study led by scientists at St. Jude Children's Research Hospital, with multiple collaborating institutions, used state-of-the-art genomic techniques to profile 619 children and adults with aplastic anemia.
 
 
 Impaired protein recycling drives T cell exhaustion in cancer
 
Impaired protein recycling drives T cell exhaustion in cancerT cells are crucial components of our immune system, serving as critical protectors against infection and disease.
 
 
 Marigold flower as a sustainable plant protein for food innovation
 
Marigold flower as a sustainable plant protein for food innovationMarigold flower proteins exhibit solubility, emulsifying, and antioxidant properties with potential applications in food formulation.
 
 

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