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The latest immunology news from News Medical |
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Overcoming Challenges in Inflammasome Drug Discovery
As interest in NLRP3 and other inflammasome targets grows, drug developers face a critical challenge: demonstrating efficacy, selectivity, and safety early in the discovery pipeline. Explore recent breakthroughs in inflammasome biology, pitfalls that can derail even the most promising candidates, and how advanced models and tools are increasing predictability.
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| |  | | | An antibody test for the infectious disease Mpox was successfully developed during the new clade 1b outbreak in Rwanda, the first time that an assay of its kind has been validated within this setting. | | | | | Learn how BeSEC enables precise analysis of antibody aggregation and molecular weight through dual-angle light scattering. | | | | | Fred Hutch Cancer Center scientists reached a crucial milestone in blocking Epstein Barr virus (EBV), a pathogen estimated to infect 95% of the global population that is linked to multiple types of cancer, neurodegenerative diseases and other chronic health conditions. | | | | | Certain antibodies inhibit Mycobacterium tuberculosis, the cause of tuberculosis (TB), the infectious disease that claims the most lives worldwide, a study led by UT Southwestern Medical Center researchers found. | | | | | Researchers at The Jackson Laboratory (JAX), in collaboration with the Massachusetts Institute of Technology (MIT), have developed the first bandage-like microneedle patch that can sample the body's immune responses painlessly from the skin. The device detects inflammatory signals within minutes and collects specialized immune cells within hours without the need for blood draws or surgical biopsies. | |
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