Drug Discovery - Scientists turn plastic waste into Parkinson’s drug levodopa using engineered bacteria
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Addressing key challenges in drug discovery and developmentAddressing key challenges in drug discovery and development

Escalating costs and increasing demands from regulatory authorities for a precision medicine-based approach to drug development challenge the pharmaceutical industry. Olink’s PEA technology supports drug target discovery and the analysis of clinical trial samples, enabling biomarker-defined subgroup exploration, assessment of pharmacodynamic responses, and deeper insights into disease biology and drug mechanisms.

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   Scientists turn plastic waste into Parkinson’s drug levodopa using engineered bacteriaScientists turn plastic waste into Parkinson’s drug levodopa using engineered bacteria
 
Researchers engineered a two-strain microbial system that converts PET-derived terephthalic acid into levodopa, overcoming key bottlenecks in transport and enzyme inhibition. The proof-of-concept process achieves high yields under mild conditions and demonstrates a potential route for upcycling plastic waste into valuable pharmaceuticals.
 
   A New Framework for High-Efficiency Drug DevelopmentA New Framework for High-Efficiency Drug Development
 
A research team under the direction of the Medical University of Vienna has identified a potential new method for drug development in a recently published review.
 
 Machine learning model predicts chemical reactions to accelerate drug discovery
 
Machine learning model predicts chemical reactions to accelerate drug discoveryDrug discovery is like molecular Tetris. Chemists snap atoms together, adjusting the pieces until everything fits and suddenly, a molecule makes a promising new medicine.
 
 
 Review examines clinical trial phases in drug development
 
Review examines clinical trial phases in drug developmentAnnouncing a new article publication for BIO Integration journal. Clinical trials bridge basic research and clinical application, serving as essential steps in drug development.
 
 
 Solving a 50-year Bottleneck in Chemotherapy Drug Production
 
Solving a 50-year Bottleneck in Chemotherapy Drug ProductionA multinational team of researchers has made a significant advance in the manufacturing of doxorubicin, a crucial chemotherapy drug.
 
 
 Clinical trial to assess safety, efficacy of new implant for male stress urinary incontinence
 
Clinical trial to assess safety, efficacy of new implant for male stress urinary incontinenceUrologists at Vanderbilt Health are enrolling men with stress urinary incontinence (SUI) in a clinical trial named SOPHIA2 to assess the safety and efficacy of the UroActive implant, following an investigational device exemption clearance from the U.S. Food and Drug Administration and the French National Agency for the Safety of Medicines and Health Products.
 
 
 Clinical trial tests a newer, targeted therapy for IDH mutant astrocytoma
 
Clinical trial tests a newer, targeted therapy for IDH mutant astrocytomaA new clinical trial led by the Alliance for Clinical Trials in Oncology will investigate if a combination of drug therapies after radiation therapy improves outcomes for people with newly-diagnosed, grade 3 IDH-mutant astrocytoma, a type of brain cancer.
 
 

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