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The latest drug discovery news from News Medical |
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 Free Guide - Everything About Renal Proximal Tubule Cells
Explore how a human-relevant kidney model is reshaping preclinical research. This eBook provides scientific insights, real-world applications, and protocols for predicting nephrotoxicity and studying renal disease. A must-read for researchers focused on improving drug screening and kidney studies.
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| | | | |  Researchers have demonstrated that E. coli can perform a biocompatible Lossen rearrangement, enabling phosphate-catalysed conversion of synthetic substrates into valuable compounds. This approach allows engineered bacteria to upcycle PET plastic waste into paracetamol, highlighting a novel intersection of chemistry and biotechnology. | | | | |  A combination therapy that adds a recently approved drug to the current standard of care for newly diagnosed acute myeloid leukemia (AML) showed high rates of complete remission in an early-phase clinical trial conducted at UNC Lineberger Comprehensive Cancer Center and 11 other sites nationwide. | | | | |  Northwestern's SOAR database enhances drug discovery by mapping gene activity, aiding researchers in identifying treatment targets and understanding diseases. | | | | |  Bio-Rad Laboratories, Inc., a global leader in life science research and clinical diagnostics products, today extended its range of recombinant monoclonal anti-idiotypic antibodies with the introduction of antibodies specific to pertuzumab (Perjeta), guselkumab (Tremfya), canakinumab (Ilaris), belimumab (Benlysta), and the bispecific drug emicizumab (Hemlibra). | | | | |  About 30% of all respiratory tract infections are caused by coronaviruses, leading to widespread illnesses and, in some cases, to epidemic and even pandemic outbreaks, as we experienced with the COVID-19 pandemic. | | | | |  A simple intervention, similar to the tension applied to the arm during a blood pressure reading, is being tested in a Phase II clinical trial to see if it can help cancer patients treated with common chemotherapy drugs, called anthracyclines, avoid heart failure. | | | | |  A new clinical trial found that taking a popular diabetes and weight-loss drug once weekly significantly improves blood sugar and leads to substantial weight loss in adults with Type 1 diabetes who use automated insulin delivery systems. | | | | |  Researchers found that once-monthly maridebart cafraglutide led to substantial weight loss and improved glycemic control in adults with obesity, with or without diabetes, in a phase 2 randomized trial. The drug demonstrated an acceptable safety profile and supports further study in phase 3 trials. | |
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