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Researchers develop 3D cultured cells that mimic liver fibrosis

Headed by researchers from Japan-based Tokyo University of Agriculture and Technology (TUAT), a group of scientists has effectively established three-dimensional (3D) cultured tissue that imitates liver fibrosis, which is a major trait of non-alcoholic steatohepatitis (NASH).

2 Apr 2020

New small molecules show promise for treating obesity and other disorders

Researchers have successfully identified novel compounds to prolong the period of the circadian clock and have also explained their mechanisms of action.

2 Apr 2020

Discovery Of New Biomarker In Blood Could Lead To Early Test For Alzheimer's Disease

Researchers discovered that high blood levels of RNA produced by the PHGDH gene could serve as a biomarker for early detection of Alzheimer's disease.

From UC San Diego 2 Apr 2020

Researchers Discover Potential Boost To Immunotherapy

Researchers have discovered a pathway that regulates special immune system cells in lung cancer tumors, suppressing them and allowing tumors to grow.

2 Apr 2020

Hidden Messages In Protein Blueprints

Scientists from DKFZ, HI-STEM have identified a new control mechanism that enables stem cells to adapt their activity in emergency situations.

2 Apr 2020

A Plant-Based Diet Helps To Prevent And Manage Asthma, According To New Review

A plant-based diet can help prevent and manage asthma, while dairy products and high-fat foods raise the risk, according to a new review.

2 Apr 2020

New cell therapy proves effective in human and mouse tumor models

A new study published recently in eLife reports that researchers have developed new immunotherapy that eliminates solid tumors in mice without causing detrimental side effects.

1 Apr 2020

Study unveils genetic variants that play key role in psychiatric, neurological conditions

The cerebral cortex is important for memory, thinking, attention, and information processing. It is an outer, folded, and comparatively thin “gray matter” layer of the brain.

27 Mar 2020

Study finds large gaps in the scientific knowledge of cannabis genome

In an international study published recently, researchers from the University of Saskatchewan report that combined scientific effort would be needed to assemble and map the genome of cannabis to unravel its full potential for human health and agriculture.

26 Mar 2020

Study develops high-resolution maps of microbial communities on the human tongue

Scientists in the United States have used a newly developed fluorescent imaging technique to create high-resolution maps of microbial communities on the human tongue.

25 Mar 2020

Large mutations may explain diverse outcomes from autism genes

Scientists have recently discovered large mutations that may explain diverse outcomes from autism genes and this story investigates further.

25 Mar 2020

Study discovers the mode of action of daptomycin, the reserve antibiotic

The reserve antibiotic daptomycin is one of the last means to fight against harmful bacteria. It is specifically used when traditional drugs fail due to bacteria that are resistant.

23 Mar 2020

New method for mapping the structures of heparan sulfate sugars

Heparin, the blood-thinning drug, is used worldwide. However, to date, mapping of the fundamental sugar structures of heparin and the wider class of heparan sulfate sugars in cells has not been accomplished.

23 Mar 2020

Regulating ion flow using a ball-and-chain mechanism

Ion channels that permit potassium and sodium ions to move in and out of cells are essential for the function of the brain and heart, and also for neuronal “firing” in the central nervous system.

19 Mar 2020

Study finds fatty acid uptake is greater in cells that lack EHD2 protein

Several foods such as mozzarella on a pizza, the olive oil in salad dressing, or hollandaise sauce used on asparagus contain lots of fat.

18 Mar 2020

New CRISPR technology targets thousands of genes

Thanks to CRISPR-based genetic screens, researchers were able to detect genes that play a major role in lung cancer metastasis, cancer immunotherapy, sickle-cell anemia, and a host of other medical disorders.

18 Mar 2020

Study demonstrates ability of blended electrospun mat to gradually release protein

Russian scientists from the Federal Research Clinical Center of Physical-Chemical Medicine, the Moscow Institute of Physics and Technology, and Lomonosov Moscow State University have shown that it is possible to combine two incompatible components—a protein and a polymer—in one electrospun fiber.

17 Mar 2020

New canine study can benefit diagnostics and treatment of retinitis pigmentosa

A study performed on canines at the University of Helsinki characterizes a gene variant in the regulatory region of the retina that causes abnormal functioning of retinal genes and, ultimately, leads to loss of vision in dogs.

11 Mar 2020

Research on mice shows unexpected effect of intermittent fasting on fat metabolism

Australian scientists have used sophisticated analytical tools to understand the effect of intermittent fasting on the liver to help mitigate disease.

11 Mar 2020

Study explores the impact of solute carriers on the activity and potency of cytotoxic drugs

At the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, scientists have investigated how solute carriers (SLCs)—a large class of membrane transport proteins—affect the activity and potency of cytotoxic drugs, for example, those used to treat leukemia and other cancers.

10 Mar 2020