Overview

PhotoDextran® from Advanced Matrix is known to be a 1 gm of lyophilized methacrylated dextran. PhotoDextran® offers 3D hydrogels that could be made at multiple concentrations and photocrosslinked (needs a photoinitiator).

This is done to offer several gel stiffnesses. Also, it could be mixed with other photocrosslinkable ECMs.

Advanced BioMatrix provides PhotoDextran®, a methacrylated dextran for photocrosslinkable hydrogels or integrating inside photocrosslinkable hydrogels (like PhotoCol, PhotoGel, or PhotoHA).

PhotoDextran® offers native-like 3D gels with special attributes: It could be made at several concentrations and photocrosslinked in a range of methods to offer a truly tunable gel stiffness. PhotoDextran® could be ordered by itself (1 gm lyophilized sterile powder), or as a kit that is available with a photoinitiator for photocrosslinking.

PhotoDextran®

Image Credit: Advanced Matrix

Table 1. Source: Advanced Matrix

Item Catalog Number Photoinitiator Included
PhotoDextran #5311 N/A
PhotoDextran with Irgacure #5331 Irgacure (365 nm)
PhotoDextran with LAP #5332 LAP (405 nm)
PhotoDextran with Ruthenium #5333 Ruthenium (400-450 nm)

 

As soon as it is solubilized, the PhotoDextran® could be stored at 2 to 10 °C for almost one month.

Table 2. Source: Advanced Matrix

Parameter, Testing, and Method Methacrylated Dextran #5311
Sterilization Method Filtration
Sterility - USP modified No growth
Form Lyophilized Powder
Package Size 1 gram
Storage Temperature -20 °C
Shelf Life Minimum of 6 months from date of receipt
Shelf Life After Reconstitution 1 Month
Degree of Methacrylation 45-65%
Molecular Weight 35,000-50,000 Da
Endotoxin - IU/g <10

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