Gastroenterology News and Research

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Gastroenterology is the branch of medicine where the digestive system and its disorders are studied.

Mount Sinai and Regeneron Genetics Center launch a large-scale genome sequencing project

Mount Sinai Health System and the Icahn School of Medicine at Mount Sinai have launched a new human genome sequencing research project called the Mount Sinai Million Health Discoveries Program with the Regeneron Genetics Center (RGC), part of the industry-leading, New York-based biotechnology company Regeneron.

12 Aug 2022

Research highlights how microbe-free mice absorb fat using different sets of genes

According to a recent Duke research in mice, the microbes that assist break down food instruct the gut on how to do their job better.

18 May 2022

Researchers discover a protein that protects the pancreas from self-digestion

The pancreas secretes around a cup of digestive juices per day—a mixture of molecules capable of breaking down the food people consume.

22 Apr 2022

Gut viruses contribute to human health, but provoke inflammation when perturbed

Research in recent years has demonstrated the diverse roles that gut bacteria can play in health and disease, but what about contributions from viruses, which, like bacteria, perpetually reside within the human intestine?

11 Apr 2022

New scalable method to advance maturation of human pluripotent stem cell-derived cardiomyocytes

A Mount Sinai-led team has developed a reproducible and scalable method to advance maturation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs)-;cells that support heart muscle contraction, generated in the lab from human stem cell lines-;which researchers say will improve approaches for disease modeling, regenerative therapies, and drug testing.

8 Apr 2022

CDH17CAR T cells can eliminate solid tumors without damaging healthy tissues

Chimeric antigen receptor (CAR) T cells can be remarkably effective in treating leukemias and lymphomas, but there are no successful immunotherapies for neuroendocrine tumors (NETs) and gastrointestinal cancers (GICs) yet.

25 Mar 2022

Fungi residing in the intestines protect against intestinal injury, study finds

According to a recent preclinical study from Weill Cornell Medicine, a certain species of fungus found in the intestines can protect against intestinal damage.

22 Feb 2022

Experts explore the relationships between diet, gut bacteria, and metabolites

Researchers currently understand that the microorganisms that dwell in human intestines—the microbiome—have a wide range of effects on human health.

14 Feb 2022

Groundbreaking discovery could lead to the design of novel therapeutics for wound-healing

An international team led by the Case Western Reserve University School of Medicine has discovered novel properties of the protein Gasdermin B that promotes repair of cells lining the gastrointestinal tract in people with chronic inflammatory disorders like Crohn's disease and ulcerative colitis.

8 Feb 2022

New method helps distinguish bacterial DNA from human and other non-bacterial cells

For decades, a small group of cutting-edge medical researchers have been studying a biochemical, DNA tagging system, which switches genes on or off. Many have studied it in bacteria and now some have seen signs of it in, plants, flies, and even human brain tumors.

4 Feb 2022

MIT researchers develop new way to deliver RNA in a capsule

Like most vaccines, RNA vaccines have to be injected, which can be an obstacle for people who fear needles. Now, a team of MIT researchers has developed a way to deliver RNA in a capsule that can be swallowed, which they hope could help make people more receptive to them.

1 Feb 2022

Coffee found to have a stimulating effect on some digestive processes

A new scientific review, published in Nutrients, highlights coffee's effects on digestion and the gut, and its impact on organs involved in digestion.

19 Jan 2022

Risk linked to coronary arteriosclerosis may be explained by changes in gene networks

Up to 60 percent of the risk associated with coronary arteriosclerosis may be explained by changes in the activity of hundreds of genes working together in networks across several organs in the body.

17 Jan 2022

Changes in the activity of gene networks may explain arteriosclerosis risk

Up to 60 percent of the risk associated with coronary arteriosclerosis may be explained by changes in the activity of hundreds of genes working together in networks across several organs in the body.

13 Jan 2022

A genetic variation makes sugar healthy for some Greenlanders

A genetic variation among some Greenlanders makes sugar healthy – significantly more than for most people.

23 Dec 2021

Scientists find how cells remain dormant for years before awakening to create metastatic cancer

Mount Sinai researchers have solved a major mystery in cancer research: How cancer cells remain dormant for years after they leave a tumor and travel to other parts of the body, before awakening to create metastatic cancer.

14 Dec 2021

Synthetic food additive causes detrimental effects on the gut microbiota

New clinical research indicates that a widely used food additive, carboxymethylcellulose, alters the intestinal environment of healthy persons, perturbing levels of beneficial bacteria and nutrients.

1 Dec 2021

Antibodies play a major role in managing gut mycobiota, says study

According to recent research, antibody protection against harmful forms of fungi in the gut might be disrupted in some patients with Crohn’s disease.

25 Nov 2021

New drug delivery strategy could make it easier for patients to take their medications

In recent years, scientists have developed monoclonal antibodies -; proteins that mimic the body's own immune defenses -; that can combat a variety of diseases, including some cancers and autoimmune disorders such as Crohn's disease.

31 Aug 2021

Old habit-controlling neurons may also play a key role in learning new tricks

Imagine working on your computer and typing the same long password you have used for years to access your email.

26 Aug 2021