Microscopy

Microscopy is an umbrella term to describe techniques used to analyse small samples that cannot be viewed with the naked eye. There is a wide range of microscopy techniques and scientific instruments available that can be used depending on their applications. A microscope magnifies tiny objects or samples and can provide a wealth of vital information about their cell structure, contamination, parasites and so much more.

This hub will contain all of the information you need to know about microscopy and will include the latest news and fascinating research articles. Whether you are looking to expand your knowledge of compound microscopes or fluorescence microscopy, you will find it all here under featured articles and the latest interviews.

What is Microscopy?

The word microscope is derived from the Greek “mikros”, meaning small and, “skopein” meaning to see.

Microscopy and Artificial Intelligence

Scanning Electron Microscopy (SEM): An Overview

Investigating the Intersection between Microscopy and Healthcare

Fluorescence Microscopy: An Overview

Using Scanning Electron Microscopy to Image SARS-CoV-2

Confocal Microscopy: An Overview

Electron Microscopy: An Overview

Using Electron Microscopy to Detect Viruses

Applications of Scanning Electron Microscopy

Uses of Microscopy in Forensics

What are Polarized Light Microscopes and How Do They Work?

See more featured articles »

Role of Microscopy in Ballistics

Applications of Polarized Light Microscopy

Phase-Contrast Microscopy: An Overview

Avoiding Cell Death in Fluorescence Microscopy

Photobleaching in Fluorescence Microscopy

TEM Imaging Modes

Visualizing the 3D Architecture of Tissues

What is Confocal Imaging?

The Determination of Post-Mortem Interval (PMI) Using Transmission Electron Microscopy

The Digital Evolution of Microscopy

What is FIB-SEM?

‘Staining’ of Biological Samples when Using Electron Microscopy: Why stain density matters

Why Size Matters in Microscopy

Light Microscopy Techniques in Virology: An Overview

Identifying Corpses Using Microscopy

What is Environmental Forensic Microscopy?

Imaging Techniques in Drug Discovery

Microscopy and Artificial Intelligence

Deep Learning in Fluorescence Microscopy

Optimizing Live Cell Imaging with FRET Microscopy

‘Staining’ of Biological Samples when Using Electron Microscopy: Why stain density matters

Applications of IVIS (In Vivo Imaging Systems)

Advances in Scanning Electron Microscopy

Microscopes in Forensic Epidemiology- An Overview

What is 3D X-Ray Microscopy?

TEM Imaging Modes

Imaging Nuclear Structures Using AFM

Advances in Fluorescence Microscopy

Cryo-Electron Microscopy: An Overview

Confocal Reflection Microscopy for Cell Migration Studies

Transmission Electron Microscopy: An Overview

How do Epifluorescence Microscopes Work?

What is High-Resolution TEM (HR-TEM)?

Applications of 3D X-ray Microscopy

Two-photon Microscopy Principles and Methodology

Advantages and Limitations of Fluorescence Microscopy

Optical Microscopy: An Overview

Light Microscopy Techniques in Virology: An Overview

Optimizing Live Cell Imaging with FRET Microscopy

Using Microscopy for Deep In Vivo Brain Imaging

Microscopy’s Involvement in Brain Imaging

Differentiating Tumors using Microscopy

Expansion Microscopy in Neurology

Scanning Helium Microscopy: An Overview

X-ray Microscopy: An Overview

Diagnosing Alzheimer's Using Microscopy

Intravital Kidney Microscopy: An Overview

Investigating the Applications of Meoscopy

What is Expansion Microscopy?

Latest Microscopy News and Research

New Delivery Mechanism Brings Messenger RNA to the Point of Need in Neurons

Brain cells manufacture proteins in every corner, including their long branches. Neurons missing this ability cause severe neurological disorders like disability and epilepsy.

5 Jun 2023

Identifying How a Particular Riboswitch Regulates its Synthesis

Researchers across the world are in search of ways to combat bacteria that could evade the present arsenal of antibiotics. This is done as a measure to avoid a global health crisis.

2 Jun 2023

Newly Identified Cellular Mechanism Enhances Photosynthesis in Marine Phytoplankton

Take a deep breath. Now take nine more. According to new research, the amount of oxygen in one of those 10 breaths was made possible thanks to a newly identified cellular mechanism that promotes photosynthesis in marine phytoplankton.

1 Jun 2023

Using High-Energy X-Rays to Image Biological Specimens Without Damage

A pollen grain showing the nanofoam within or a diatom with the individual geometric structures inside clearly visible: Using high-energy X-rays from the PETRA III synchrotron light source at DESY, a team led by CFEL scientists Saša Bajt and Henry Chapman has managed to image these structures without damaging them.

31 May 2023

High-Resolution, Stable Brain Stimulation by Ultraflexible Nanoelectrodes

Conventional implantable medical devices designed for brain stimulation are often too rigid and bulky for what is one of the body's softest and most delicate tissues.

31 May 2023

How the Disturbed Recycling Chain of Endoplasmic Reticulum Causes Neurodegenerative Diseases

Our cells are crisscrossed by a system of membrane tubes and pockets called the endoplasmic reticulum (ER). It is crucial for the production of biomolecules and is continuously built up and degraded.

29 May 2023

How Epigenetic Landscape Impacts Pioneer Transcription Factor Binding

St. Jude Children’s Research Hospital researchers are investigating how a type of transcription factor known as a pioneer transcription factor reaches DNA even when it is tightly wrapped.

25 May 2023

Blebs: How Rapidly Protrusions for Movement and Exploration Emerge in Cells

Cells need to be able to quickly alter their form if they are to migrate. Cells do this by storing additional “skin” amid folds and bumps on their surface, according to a team of researchers from the University of North Carolina in Chapel Hill.

19 May 2023

TTUHSC Professor Awarded NIH Grant for Potassium Channel Study

Each living cell has small, highly specialized conduits called potassium (K+) channels, which are responsible for the highly selective and fast transfer of K+ ions across cell membranes.

19 May 2023

Researchers Use the Bionanoprobe to Explore Role of Zinc in Follicle Development

The discovery that zinc is involved in the fertilization process earlier than initially thought was made with the help of the Bionanoprobe, a cutting-edge instrument at Argonne.

18 May 2023

Study Provides a New Picture of How Bacterial Cells Repair Faulty DNA

A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA.

17 May 2023

Long-Ignored Antibiotic may Provide Much-Needed Protection Against Multi-Drug Resistant Bacteria

An old antibiotic may provide much-needed protection against multi-drug resistant bacterial infections, according to a new study publishing May 16th in the open access journal PLOS Biology by James Kirby of Harvard Medical School, US, and colleagues.

17 May 2023

Fecal Microbiota Transplantation to Help in Clostridioides difficile Infection

In Europe, Clostridioides difficile infection results in severe diarrhea and leads to the death of around 20,000 patients, every year. It is one of the most common hospital-acquired infections.

16 May 2023

Robust AI System Identifies Protein Patterns Within Individual Cells

A highly innovative artificial intelligence (AI) system identified protein patterns within individual cells with world-leading accuracy and speed.

From University of Surrey 16 May 2023

AI Used to Create 3D Model of 'Postal Workers' in Human Cells

University of Queensland researchers have used artificial intelligence to build a 3D map of key cell components to better understand dementia and infectious diseases including COVID-19.

12 May 2023

Research Helps Better Understand How Developing Cells Break Free From Their Tissue of Origin

Cancer's ability to spread throughout the body -; a process known as metastasis -; is responsible for the vast majority of cancer deaths.

11 May 2023

Researchers Develop a System to Deliver Antioxidants to the Mitochondria

A new drug delivery system delivers an antioxidant directly to mitochondria in the liver, mitigating the effects of oxidative stress.

11 May 2023

Tokyo Tech Researchers Discover How Surface Chemistry can Influence Adhesion of Bacterial Cells

The biofilm-forming bacteria E. coli adheres firmly to hydrophobic and hydrophilic protein-adsorbing self-assembling monolayers (SAMs) and weakly to hydrophilic protein-resisting SAMs, uncovered a recent study by Tokyo Tech researchers.

8 May 2023

Analyzing the Complex Sequence of Events Involved in Beta-Arrestin Interactions

Proteins that work like air traffic controllers, controlling the flow of signals in and out of human cells, have been examined in unparalleled detail for the first time using modern microscope techniques.

5 May 2023

Analyzing the Cell Division in Stem Cells

What appears to be a simple task for a cell—splitting in two—is indeed a complex series of engineering puzzles. To produce two working cells, a splitting cell has to maneuver its interiors in such a way that the appropriate components will end up in each cell.

3 May 2023

Microscopy

Overview

Feature Articles

Fluorescence Microscopy: An Overview

Using Scanning Electron Microscopy to Image SARS-CoV-2

Confocal Microscopy: An Overview

Electron Microscopy: An Overview

Using Electron Microscopy to Detect Viruses

Applications of Scanning Electron Microscopy

Uses of Microscopy in Forensics

What are Polarized Light Microscopes and How Do They Work?

Role of Microscopy in Ballistics

Applications of Polarized Light Microscopy

Phase-Contrast Microscopy: An Overview

Avoiding Cell Death in Fluorescence Microscopy

Photobleaching in Fluorescence Microscopy

TEM Imaging Modes

Visualizing the 3D Architecture of Tissues

What is Confocal Imaging?

The Determination of Post-Mortem Interval (PMI) Using Transmission Electron Microscopy

The Digital Evolution of Microscopy

What is FIB-SEM?

‘Staining’ of Biological Samples when Using Electron Microscopy: Why stain density matters

Why Size Matters in Microscopy

Light Microscopy Techniques in Virology: An Overview

Identifying Corpses Using Microscopy

What is Environmental Forensic Microscopy?

Imaging Techniques in Drug Discovery

Microscopy and Artificial Intelligence

Deep Learning in Fluorescence Microscopy

Optimizing Live Cell Imaging with FRET Microscopy

‘Staining’ of Biological Samples when Using Electron Microscopy: Why stain density matters

Applications of IVIS (In Vivo Imaging Systems)

Advances in Scanning Electron Microscopy

Microscopes in Forensic Epidemiology- An Overview

What is 3D X-Ray Microscopy?

TEM Imaging Modes

Imaging Nuclear Structures Using AFM

Advances in Fluorescence Microscopy

Cryo-Electron Microscopy: An Overview

Confocal Reflection Microscopy for Cell Migration Studies

Transmission Electron Microscopy: An Overview

How do Epifluorescence Microscopes Work?

What is High-Resolution TEM (HR-TEM)?

Applications of 3D X-ray Microscopy

Two-photon Microscopy Principles and Methodology

Advantages and Limitations of Fluorescence Microscopy

Optical Microscopy: An Overview

Light Microscopy Techniques in Virology: An Overview

Optimizing Live Cell Imaging with FRET Microscopy

Using Microscopy for Deep In Vivo Brain Imaging

Microscopy’s Involvement in Brain Imaging

Differentiating Tumors using Microscopy

Expansion Microscopy in Neurology

Scanning Helium Microscopy: An Overview

X-ray Microscopy: An Overview

Diagnosing Alzheimer's Using Microscopy

Intravital Kidney Microscopy: An Overview

Investigating the Applications of Meoscopy

What is Expansion Microscopy?

Latest Microscopy News and Research

Life Science Newsletters

Analytical Chemistry in Life Sciences

Antibodies

Biochemistry

Biotechnology

Cannabis Testing & Analysis

Cell Biology

Clinical and Lab Diagnostics

Drug Discovery and Production

Flow Cytometry

Fluorescence

Forensics & Toxicology

Genomics

Immunology

Life Science Microscopy

Metabolomics

Microbiology

Protein Analysis

Stem Cells