Drug Discovery, Manufacturing and Development

The process starting from the creation of a new molecule until its introduction into clinical use is broadly referred to as drug development. Drug discovery and development include a wide range of stages, including clinical trials, approval from regulatory bodies such as the food and drug administration (FDA), and finally bringing a new drug to the market.

Drug Discovery, Manufacturing, and Development

The process starting from the creation of a new molecule until its introduction into clinical use is broadly referred to as drug development.

Overview

Whether you’re looking for more information on pharmaceutical manufacturing, medicinal chemistry or anything else to do with drug production, this site is a hub for all of the latest news and research regarding drug development.

Investigating the Relationship between Pharma and Biotech within the Life Sciences

Modern Challenges of Drug Discovery

Insight into Next-Generation Protein Therapeutics

Feature Articles

From drug applications to side effects of active pharmaceutical ingredients, our featured articles are selected to bring you a range of recent case studies, new developments and interesting works on drug discovery and development.

The Current Global State of Drug Discovery

A Guide to Understanding the Drug Discovery Process

How Important is Lab Automation to Drug Discovery?

Importance of Collaboration within the Drug Discovery Sector

The Importance of Discovering New Drugs

The Importance of the Human Microbiome in Drug Discovery

In Silico Drug Design Methods

Antisense Technology in Drug Discovery

See more featured articles »

What are Microbiome-Derived Antibiotics?

Searching for New Drugs using CRISPR

The Influence of the Microbiome on Drug Action

What is a Clinical Trial?

Imaging Techniques in Drug Discovery

Applications of 3D printing in Drug Delivery

Computational Methods in Drug Discovery

Human Blood-Brain Barrier on a Chip

Drug Discovery in Plants

Peptidomimetics in Drug Discovery

Investigating the Importance of Assays in Drug Discovery and Development

Adopting AI to Boost Drug Discovery

Using Artificial Intelligence to Discover New Antibiotics

What are Biologics?

What Role Does Epigenetics Play in Drug Discovery?

Applying NMR to Study Small-Molecule Interactions in Drug Discovery

How can Quantum Computing Benefit Drug Discovery?

Applications of Ingestible Electronics

Pluripotent Stem Cells

What are Peptide Decoys?

Role of High-Content Screening in Discovering New Cancer Drugs

Role of Molecular Docking in Drug Discovery

Importance of Nanomedicine in Cancer Therapy

What Role do Disease Models Play in Accelerating Drug Development?

Importance of Drug Sensitivity Testing in Cancer

Drug Discovery, Manufacturing, and Development

What Role Does Genomics Play in Drug Repurposing?

How can Snake Venom Help Aid Drug Discovery?

Role of RNA as a Drug Target

What is Molecular Docking?

Global Market Overview: Organ-on-a-Chip

Using Artificial Intelligence to Discover New Antibiotics

What are Therapeutic Antibodies?

Applications of Ingestible Electronics

Applying NMR to Study Small-Molecule Interactions in Drug Discovery

What Role Does Epigenetics Play in Drug Discovery?

Importance of Nanomedicine in Cancer Therapy

Genome Editing Applications in Drug Discovery

Neuroprotective Drugs: Future Developments in Treating Vascular Dementia

How to Achieve Drug Solubility

What are Designer Antiviral Peptides?

Stem Cell-Derived Hepatocytes: A Brave New World?

Role of ncRNA in Drug Discovery

What is Retrometabolic Drug Design?

The Removal of Senescent Cells to Improve Organ Function

Advancements in Paper-Based Analytic Devices for Drug Analysis

Drug Analysis of Vitreous Humor

What is Lipinski's Rule of 5?

What are Protein Degraders?

How can Standardization Help to Accelerate Drug Discovery?

Identifying 'Legal Highs'

Helping Identify Novel Psychoactive Substances

What Role do Biomarkers Play in Drug Discovery?

What is Epitranscriptomics?

What are Aptamers?

What are Peptide Therapeutics?

What is DNA-Encoded Libraries Technology (DELT)?

Combating the Opioid Epidemic

What is Cancer Biotherapeutics?

How could Stem Cells be Used in Drug Discovery?

Importance of Streamlining the Drug Discovery Process

What is Pharmacovigilance?

AIs Involvement in Improving Drug Discovery

How does Increasing Drug Resistance affect Drug Discovery?

What are New Chemical Entities (NCE)?

How do DNA Nanostructures help in Drug Delivery?

Role of Hybrid Nanoplatforms in Drug Discovery

Blood-Brain Barrier Models for Oncology Research

Revealing Drug Use in Your Hair

Application of High-Throughput Screening in Drug Discovery

Role of Bioinformatics in Drug Discovery

Analyzing Cling Film Used in the Packaging of Illicit Drugs

Detecting Illicit Drug Use From your Fingerprints

Dangers of Ibuprofen and Chiral Class Drugs

What are Antibody-Drug Conjugates?

Detecting Drug Levels in Blood

Drug Detection Methods

How does Antibiotic Resistance Occur?

Discovering New Drug Targets Using High-Throughput Screening

Computer-Aided Drug Design: An Overview

Problems with Pulmonary Drug Delivery

Purpose of ADME Studies in Drug Development

Understanding Lead Optimization

Hit to Lead (H2L) Process in Drug Discovery

How is Chemoinformatics Used in Drug Discovery?

How is Additive Manufacturing Used in the Pharmaceutical Industry?

Counterfeit Drug Detection

What is Subcellular Drug Imaging?

Importance of Solubility and Lipophilicity in Drug Development

Carbon Nanotubes and Drug Delivery

Are Peptides the Future of Medicine?

What is Forensic Toxicology?

Applying DART to Drug Screening

Targeting Cancer Cells using HSP90 Inhibitors

Improving the Treatment of Snakebite

Insight into Rational Drug Design

The Use of Marine Invertebrates in Drug Discovery

Detecting New Synthetic Street Drugs

The Concept of Druglikeness in Drug Discovery

Suits You; Challenges in Personalized Medicine

How Could the Assembly Theory Improve Drug Discovery?

Wastewater Analysis of Psychoactive Drugs

Improving Selectivity in Drug Design

Assembling New Molecules to Discover New Medicines

What Factors Affect the Efficiency of Drug Approval?

High-Content vs. High-Throughput Screening Technologies

What Role does Big Pharma Play in Accelerating New Technologies?

What is Pharmacognosy?

Importance of Repurposing Drugs

Why does Drug Development have such a High Failure Rate?

Advancements in the Development of Oral Therapeutics for Diabetes

Optimizing Drug Delivery Using AI

What are Polymorphs?

What Role does Collaboration have within the Drug Discovery Sector?

Investigating the Biggest Challenges in Drug Discovery

Is Synthetic Biology the Next Big Thing for Biopharma?

Investigating the Challenges Surrounding Biotherapeutics

What is High-Content Screening?

The Role of Polymers in Drug Delivery

Hotspot Mapping in Drug Design and Development

Insight into Drug Delivery Methods

What is High Throughput Screening?

What are Microbial Therapeutics?

Optimizing a Drug's Pharmacokinetics

What Role Does Molecular Dynamics play in Drug Discovery?

What is Fragment-Based Drug Discovery?

Is Targeted Protein Degradation Revolutionizing Drug Development?

Pharmacokinetic–Pharmacodynamic Modeling: Understanding Drug Behavior for Improved Drug Development

Latest Drug Discovery, Manufacturing and Development News and Research

Novel “green” synthesis of drug for inflammatory bowel disease

Steroids and antibody drugs are currently used to treat inflammatory bowel disease (IBD), which is characterized by chronic inflammation of the digestive tract.

16 Mar 2022

Researchers show how hotspot maps can detect structures contributing to compounds’ selectivity

The quantity of structural data available on protein drug targets keeps growing.

4 Mar 2022

Study finds a more sustainable way to develop pharmaceuticals

University of Bath’s chemistry researchers recently devised a novel process utilizing blue light to develop pharmaceuticals in sustainable means.

From University of Bath 19 Nov 2021

Research findings anticipated to facilitate production of novel drug candidates

Pharmaceuticals commonly available on the market are developed by linking together rings of molecules to generate drugs that treat conditions like depression.

19 Nov 2021

New visible-light-based approach to structurally modify bioactive molecules

Researchers have been working on new, sustainable techniques to synthesize chemicals by leveraging the inexhaustible, green energy of visible light.

10 Nov 2021

Researchers discover that existing drug can enhance memory

A group of scientists identified that a prevailing drug for treating constipation might boost an individual’s capability to think with better clarity.

4 Oct 2021

Study pinpoints means to restore the efficacy of drugs for acute myeloid leukemia

Researchers elucidate why certain drugs, in clinical trials, for treating a kind of acute myeloid leukemia often fail and revealed a means to restore their efficacy.

1 Oct 2021

Experts unravel inner workings of cell receptors involved in various diseases

Scientists revealed the operational mechanism of possible drug targets for numerous diseases like rheumatoid arthritis, cancer, and even COVID-19.

1 Oct 2021

Novel nanofluidic device for exosome nanoporation

A team of researchers described an innovative nanofluidic device for high-throughput preparation of exosome-based drug delivery vehicles.

8 Sep 2021

Study proposes a novel approach for developing safer analgesics

Opioids are potent painkillers; however, their use is hampered as patients become tolerant to them, necessitating more and more doses.

From The University of California, Davis 31 Aug 2021

Study pinpoints genes responsible for kidney function

Recently scientists pinpointed 182 genes likely responsible for kidney function—most of which can be targeted with existing drugs.

18 Aug 2021

Insect olfaction could be used to help develop drug screening techniques

Scientists investigated a key element of the insect olfactory system to analyze how this insight might help humans.

18 Aug 2021

Graphene covered with bactericidal molecules inhibits harmful biofilm formation

Bacterial infections associated with medical implants place a major burden on healthcare and cause great suffering to patients across the world.

11 Aug 2021

Researchers create new drug database to facilitate repurposing of drugs

Scientists developed a new open-access database with information on drug candidates and the process of metabolization of the drugs by the body.

5 Aug 2021

Study highlights novel approach for designing anti-viral drugs

Scientists are exploring a novel screening approach that concentrates on the recognition of virus-specific morphological changes in virus-infected cells.

4 Aug 2021

Researchers devise a new method for safer delivery of RNA drugs

Scientists have developed and tested a library of lipid-based compounds for the safe and effective delivery of RNA drugs to the lungs.

3 Aug 2021

Researchers develop a cost-effective and versatile approach for drug synthesis

Different factors influence the cost-effectiveness of drug synthesis, the amount of waste generated being one of those.

29 Jul 2021

Study identifies many small molecules that bind to certain areas of the SARS-CoV-2 genome

Scientists at Goethe University have now identified some regions of the SARS-CoV-2 genome that might be an ideal target for future drugs.

21 Jul 2021

$Microcrystal electron diffraction could help obtain potential pharmaceutical structures$

Microcrystal electron diffraction could help obtain potential pharmaceutical structures

In the process of drug development, solving structures of potential therapeutics with X-ray diffraction (XRD) has been a presumed, critical step so far.

16 Jul 2021

New screening method allows identification of drugs that glue proteins together

Scientists developed a new screening method that tests the effectiveness of therapeutic molecules developed to “glue” proteins together in the body.

9 Jul 2021