Drug Discovery, Manufacturing and Development

Drug Discovery, Manufacturing, and Development

The process starting from the creation of a new molecule until its introduction into clinical use is broadly referred to as drug development.

Overview

A Guide to Understanding the Drug Discovery Process

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The Importance of Discovering New Drugs

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The Importance of the Human Microbiome in Drug Discovery

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Feature Articles

In Silico Drug Design Methods

Antisense Technology in Drug Discovery

Searching for New Drugs using CRISPR

The Influence of the Microbiome on Drug Action

What is a Clinical Trial?

Imaging Techniques in Drug Discovery

Applications of 3D printing in Drug Delivery

Computational Methods in Drug Discovery

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Drug Discovery in Plants

Adopting AI to Boost Drug Discovery

Using Artificial Intelligence to Discover New Antibiotics

What Role Does Epigenetics Play in Drug Discovery?

Applying NMR to Study Small-Molecule Interactions in Drug Discovery

Applications of Ingestible Electronics

Pluripotent Stem Cells

What are Peptide Decoys?

Role of Molecular Docking in Drug Discovery

Importance of Nanomedicine in Cancer Therapy

Drug Discovery, Manufacturing, and Development

Role of RNA as a Drug Target

What is Molecular Docking?

Using Artificial Intelligence to Discover New Antibiotics

What are Therapeutic Antibodies?

Applications of Ingestible Electronics

Applying NMR to Study Small-Molecule Interactions in Drug Discovery

What Role Does Epigenetics Play in Drug Discovery?

Importance of Nanomedicine in Cancer Therapy

Neuroprotective Drugs: Future Developments in Treating Vascular Dementia

How to Achieve Drug Solubility

What are Designer Antiviral Peptides?

Role of ncRNA in Drug Discovery

The Removal of Senescent Cells to Improve Organ Function

Drug Analysis of Vitreous Humor

What are Protein Degraders?

Identifying 'Legal Highs'

Helping Identify Novel Psychoactive Substances

What is Epitranscriptomics?

What are Aptamers?

What are Peptide Therapeutics?

What is DNA-Encoded Libraries Technology (DELT)?

Combating the Opioid Epidemic

What is Cancer Biotherapeutics?

How could Stem Cells be Used in Drug Discovery?

AIs Involvement in Improving Drug Discovery

How does Increasing Drug Resistance affect Drug Discovery?

How do DNA Nanostructures help in Drug Delivery?

Role of Hybrid Nanoplatforms in Drug Discovery

Revealing Drug Use in Your Hair

Application of High-Throughput Screening in Drug Discovery

Role of Bioinformatics in Drug Discovery

Analyzing Cling Film Used in the Packaging of Illicit Drugs

Detecting Illicit Drug Use From your Fingerprints

Dangers of Ibuprofen and Chiral Class Drugs

What are Antibody-Drug Conjugates?

Detecting Drug Levels in Blood

Drug Detection Methods

How does Antibiotic Resistance Occur?

Discovering New Drug Targets Using High-Throughput Screening

Problems with Pulmonary Drug Delivery

Purpose of ADME Studies in Drug Development

Understanding Lead Optimization

Hit to Lead (H2L) Process in Drug Discovery

How is Chemoinformatics Used in Drug Discovery?

How is Additive Manufacturing Used in the Pharmaceutical Industry?

Counterfeit Drug Detection

Importance of Solubility and Lipophilicity in Drug Development

Carbon Nanotubes and Drug Delivery

What is Forensic Toxicology?

Applying DART to Drug Screening

Targeting Cancer Cells using HSP90 Inhibitors

Latest Drug Discovery, Manufacturing and Development News and Research

Researchers discover that existing drug can enhance memory

Researchers discover that existing drug can enhance memory

A group of scientists identified that a prevailing drug for treating constipation might boost an individual’s capability to think with better clarity.

4 Oct 2021

Study pinpoints means to restore the efficacy of drugs for acute myeloid leukemia

Study pinpoints means to restore the efficacy of drugs for acute myeloid leukemia

Researchers elucidate why certain drugs, in clinical trials, for treating a kind of acute myeloid leukemia often fail and revealed a means to restore their efficacy.

1 Oct 2021

Experts unravel inner workings of cell receptors involved in various diseases

Experts unravel inner workings of cell receptors involved in various diseases

Scientists revealed the operational mechanism of possible drug targets for numerous diseases like rheumatoid arthritis, cancer, and even COVID-19.

1 Oct 2021

Novel nanofluidic device for exosome nanoporation

Novel nanofluidic device for exosome nanoporation

A team of researchers described an innovative nanofluidic device for high-throughput preparation of exosome-based drug delivery vehicles.

8 Sep 2021

Study proposes a novel approach for developing safer analgesics

Study proposes a novel approach for developing safer analgesics

Opioids are potent painkillers; however, their use is hampered as patients become tolerant to them, necessitating more and more doses.

31 Aug 2021

Study pinpoints genes responsible for kidney function

Study pinpoints genes responsible for kidney function

Recently scientists pinpointed 182 genes likely responsible for kidney function—most of which can be targeted with existing drugs.

18 Aug 2021

Insect olfaction could be used to help develop drug screening techniques

Insect olfaction could be used to help develop drug screening techniques

Scientists investigated a key element of the insect olfactory system to analyze how this insight might help humans.

18 Aug 2021

Graphene covered with bactericidal molecules inhibits harmful biofilm formation

Graphene covered with bactericidal molecules inhibits harmful biofilm formation

Bacterial infections associated with medical implants place a major burden on healthcare and cause great suffering to patients across the world.

11 Aug 2021

Researchers create new drug database to facilitate repurposing of drugs

Researchers create new drug database to facilitate repurposing of drugs

Scientists developed a new open-access database with information on drug candidates and the process of metabolization of the drugs by the body.

5 Aug 2021

Study highlights novel approach for designing anti-viral drugs

Study highlights novel approach for designing anti-viral drugs

Scientists are exploring a novel screening approach that concentrates on the recognition of virus-specific morphological changes in virus-infected cells.

4 Aug 2021

Researchers devise a new method for safer delivery of RNA drugs

Researchers devise a new method for safer delivery of RNA drugs

Scientists have developed and tested a library of lipid-based compounds for the safe and effective delivery of RNA drugs to the lungs.

3 Aug 2021

Researchers develop a cost-effective and versatile approach for drug synthesis

Researchers develop a cost-effective and versatile approach for drug synthesis

Different factors influence the cost-effectiveness of drug synthesis, the amount of waste generated being one of those.

29 Jul 2021

Study identifies many small molecules that bind to certain areas of the SARS-CoV-2 genome

Study identifies many small molecules that bind to certain areas of the SARS-CoV-2 genome

Scientists at Goethe University have now identified some regions of the SARS-CoV-2 genome that might be an ideal target for future drugs.

21 Jul 2021

$Microcrystal electron diffraction could help obtain potential pharmaceutical structures$

Microcrystal electron diffraction could help obtain potential pharmaceutical structures

In the process of drug development, solving structures of potential therapeutics with X-ray diffraction (XRD) has been a presumed, critical step so far.

16 Jul 2021

New screening method allows identification of drugs that glue proteins together

New screening method allows identification of drugs that glue proteins together

Scientists developed a new screening method that tests the effectiveness of therapeutic molecules developed to “glue” proteins together in the body.

9 Jul 2021

Emerging variants of COVID-19 could be treated with a new anticoagulant drug

Emerging variants of COVID-19 could be treated with a new anticoagulant drug

The capacity of the COVID-19 virus’s spikes to bind to human cells may be hampered by molecules from the same family as the anticoagulant medication heparin.

9 Jul 2021

New technique boosts the efficacy of future malaria vaccines

New technique boosts the efficacy of future malaria vaccines

A new technique for obtaining pure malaria parasites from infected mosquitos could speed up the development of novel, more powerful malaria vaccinations.

21 Jun 2021

New process reinvigorates the search for natural drugs to treat cancers

New process reinvigorates the search for natural drugs to treat cancers

A research team has devised a new method that might revitalize the hunt for natural product medications to treat viral infections, cancer, and other diseases.

4 Jun 2021

Researchers prove that drugs designed for bacteria have the potential to act on human cells

Researchers prove that drugs designed for bacteria have the potential to act on human cells

Antibiotics used to treat common bacterial infections may potentially be used to treat human illnesses such as cancer, at least theoretically.

27 May 2021

Single fingerprint can help determine whether someone has touched or ingested class A drugs

Single fingerprint can help determine whether someone has touched or ingested class A drugs

A research team explains how they were able to distinguish between the fingerprints of those who handled cocaine with those who have taken the medicine.

20 May 2021

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