Drug Discovery, Manufacturing and Development

Drug Discovery, Manufacturing, and Development

The process starting from the creation of a new molecule until its introduction into clinical use is broadly referred to as drug development.

Overview

A Guide to Understanding the Drug Discovery Process

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The Importance of Discovering New Drugs

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Antisense Technology in Drug Discovery

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Feature Articles

Searching for New Drugs using CRISPR

The Influence of the Microbiome on Drug Action

What is a Clinical Trial?

Imaging Techniques in Drug Discovery

Applications of 3D printing in Drug Delivery

Computational Methods in Drug Discovery

Drug Discovery in Plants

Adopting AI to Boost Drug Discovery

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Using Artificial Intelligence to Discover New Antibiotics

What Role Does Epigenetics Play in Drug Discovery?

Applying NMR to Study Small-Molecule Interactions in Drug Discovery

Applications of Ingestible Electronics

Pluripotent Stem Cells

What are Peptide Decoys?

Role of Molecular Docking in Drug Discovery

Importance of Nanomedicine in Cancer Therapy

Drug Discovery, Manufacturing, and Development

What is Molecular Docking?

Using Artificial Intelligence to Discover New Antibiotics

What are Therapeutic Antibodies?

Applications of Ingestible Electronics

Applying NMR to Study Small-Molecule Interactions in Drug Discovery

What Role Does Epigenetics Play in Drug Discovery?

Importance of Nanomedicine in Cancer Therapy

Neuroprotective Drugs: Future Developments in Treating Vascular Dementia

How to Achieve Drug Solubility

What are Designer Antiviral Peptides?

Role of ncRNA in Drug Discovery

The Removal of Senescent Cells to Improve Organ Function

Drug Analysis of Vitreous Humor

What are Protein Degraders?

Identifying 'Legal Highs'

Helping Identify Novel Psychoactive Substances

What is Epitranscriptomics?

What are Aptamers?

What are Peptide Therapeutics?

What is DNA-Encoded Libraries Technology (DELT)?

What is Cancer Biotherapeutics?

How could Stem Cells be Used in Drug Discovery?

AIs Involvement in Improving Drug Discovery

How does Increasing Drug Resistance affect Drug Discovery?

How do DNA Nanostructures help in Drug Delivery?

Role of Hybrid Nanoplatforms in Drug Discovery

Revealing Drug Use in Your Hair

Application of High-Throughput Screening in Drug Discovery

Role of Bioinformatics in Drug Discovery

Analyzing Cling Film Used in the Packaging of Illicit Drugs

Detecting Illicit Drug Use From your Fingerprints

Dangers of Ibuprofen and Chiral Class Drugs

What are Antibody-Drug Conjugates?

Detecting Drug Levels in Blood

Drug Detection Methods

How does Antibiotic Resistance Occur?

Discovering New Drug Targets Using High-Throughput Screening

Problems with Pulmonary Drug Delivery

Purpose of ADME Studies in Drug Development

Understanding Lead Optimization

Hit to Lead (H2L) Process in Drug Discovery

How is Chemoinformatics Used in Drug Discovery?

How is Additive Manufacturing Used in the Pharmaceutical Industry?

Counterfeit Drug Detection

Importance of Solubility and Lipophilicity in Drug Development

Carbon Nanotubes and Drug Delivery

What is Forensic Toxicology?

Applying DART to Drug Screening

Latest Drug Discovery, Manufacturing and Development News and Research

Genetically encoded sensor helps detect hallucinogenic substances

Genetically encoded sensor helps detect hallucinogenic substances

Researchers at the University of California, Davis, have created a genetically encoded sensor for detecting hallucinogenic substances.

29 Apr 2021

Developing a portable tool to detect street drug ‘spice’

Developing a portable tool to detect street drug ‘spice’

AZoLifeSciences speaks to researchers from the University of Bath about their latest research that led to the development of a device that can detect 'spice'.

28 Apr 2021

Novel test detects HIV reservoir in patients more accurately

Novel test detects HIV reservoir in patients more accurately

An innovative test that determines the quality and quantity of inactive HIV viruses in the genes of HIV patients may ultimately give scientists a better idea of effective drugs.

14 Apr 2021

New method can improve the drug testing process

New method can improve the drug testing process

When developing a new drug, the first question is, “does it work?” and the second question is, “is it harmful?”

9 Apr 2021

Researchers take a key step toward new drugs and vaccines for combating COVID-19

Researchers take a key step toward new drugs and vaccines for combating COVID-19

Scientists have achieved a huge step toward new vaccines and drugs for fighting against COVID-19.

6 Apr 2021

New AI-based method can lead to faster, low-cost development of protein-based drugs

New AI-based method can lead to faster, low-cost development of protein-based drugs

Thanks to a newly published study by scientists, artificial intelligence (AI) can now create novel and functionally active proteins.

1 Apr 2021

Study provides clues for designing more effective antiviral drugs

Study provides clues for designing more effective antiviral drugs

An international research team from the University of Turku based in Finland and PennState University based in the United States has solved an ancient puzzle of how living organisms differentiate between DNA and RNA building blocks at the time of gene expression, offering new possibilities for designing novel antiviral medications.

18 Mar 2021

Natural compound acts as reversible male contraceptive pill

Natural compound acts as reversible male contraceptive pill

Researchers have developed a novel approach that has resulted in the discovery of a natural compound that acts as a male contraceptive agent.

5 Mar 2021

New simplified approach for producing pharmaceutical substances

New simplified approach for producing pharmaceutical substances

Tetrahydroisoquinolines (THIQ) are organic compounds, whose structure includes a benzene ring merged with a nitrogen-containing cycle.

11 Feb 2021

Scientists identify new drug target for treating Hutchinson-Gilford progeria syndrome

Scientists identify new drug target for treating Hutchinson-Gilford progeria syndrome

Researchers have discovered a promising treatment method for Hutchinson-Gilford progeria syndrome (HGPS)—a debilitating genetic disorder that accounts for rapid and premature aging in children.

3 Feb 2021

Researchers identify a new compound for creating a new class of diabetes drugs

Researchers identify a new compound for creating a new class of diabetes drugs

A new study headed by the Ohio State University Wexner Medical Center and the College of Medicine has found a new compound that could form the base for creating a new class of diabetes drugs.

28 Jan 2021

Non-steroidal anti-inflammatory drugs reduce antibody and inflammatory responses to COVID-19

Non-steroidal anti-inflammatory drugs reduce antibody and inflammatory responses to COVID-19

According to a new study, non-steroidal anti-inflammatory drugs (NSAIDs) decreased both inflammatory and antibody responses to SARS-CoV-2 infection in mice.

26 Jan 2021

Novel compounds may lead to potential treatment for rare terminal childhood illness

Novel compounds may lead to potential treatment for rare terminal childhood illness

Researchers have discovered a method to “rescue” genetically mutated cells, providing opportunities to develop a new treatment for mitochondrial disease.

21 Dec 2020

Study demonstrates drug repurposing can be used to treat genetic diseases

Study demonstrates drug repurposing can be used to treat genetic diseases

A new study by researchers at the University of Illinois Chicago describes a potential technique of using drug repurposing for the treatment of genetic diseases.

18 Dec 2020

Scientists identify new target to deliver anti-cancer drugs to tumor cells

Scientists identify new target to deliver anti-cancer drugs to tumor cells

With the evolution of cancer, the quest for identifying efficient treatment techniques for cancer patients has remained challenging.

17 Dec 2020

Study shows metabolic state of disease-causing parasite influences its resistance to drugs

Study shows metabolic state of disease-causing parasite influences its resistance to drugs

A new study has revealed how a disease-causing parasite is able to resist the present range of therapies. The study was recently published in eLife.

2 Dec 2020

Researchers identify potential new treatments for blindness

Researchers identify potential new treatments for blindness

Vision loss associated with inherited genetic disease or aging is predicted to affect as many as 16 million people in the world.

27 Nov 2020

Study shows how drug-like small molecules regulate the activity of ion channels

Study shows how drug-like small molecules regulate the activity of ion channels

Researchers have recently discovered how the function of therapeutically relevant ion channels is regulated by drug-like small molecules.

24 Nov 2020

Interpretable machine learning models create new options for drug discovery

Interpretable machine learning models create new options for drug discovery

Machine learning has been extensively utilized in the chemical sciences for a wide range of processes, including drug design.

19 Nov 2020

New protein imaging technique may lead to advanced tissue analysis

New protein imaging technique may lead to advanced tissue analysis

Researchers have defined a new protein imaging technique that may result in novel discoveries in disease, cell analysis, biological tissue, and more.

18 Nov 2020

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Developing a portable tool to detect street drug ‘spice’

Dr. Chris Pudney

AZoLifeSciences speaks to researchers from the University of Bath about their latest research that led to the development of a device that can detect 'spice'.

Developing a portable tool to detect street drug ‘spice’

National DNA Day: Importance of DNA in Research

National Human Genome Research Institute

To celebrate National DNA Day, AZoLifeSciences speaks to Belen Hurle from the National Human Genome Research Institute about the importance of DNA in research.

National DNA Day: Importance of DNA in Research

National DNA Day 2021: An Interview with Professor George Church

Professor George Church

In celebration of National DNA Day, AZoLifeSciences interviews renowned DNA expert Professor George Church about his life-long career in DNA research.

National DNA Day 2021: An Interview with Professor George Church