Proteomics, Metabolomics and Lipidomics

The ‘omics revolution ensued from the surge in genetic sequencing seen in the 1990s as scientists aimed to sequence the whole human genome. Advances in sequencing and analytical technologies allowed for increased efficiency and precision, and an integrated, comprehensive approach to understanding organisms followed.
This approach is termed “’omics” and includes the following fields; genomics, transcriptomics, proteomics, fluxomics, and metabolomics. These fields collectively consider all of their respective constituents.
For example, proteomics is the large-scale study of the entire complement of proteins in cell types or organisms. Unlike it’s predecessors, genomics and transcriptomics, proteomics is more complicated as it involves the consideration of post translational modifications, such as phosphorylation. Proteomics has practical applications in protein networks where the study of ways proteins interact aids the field of systems biology, the computational and mathematical analysis and modeling of complex biological systems. Proteomic technologies can be applied to high-throughput techniques, such as mass spectroscopy.
Over the last 30 years, the ’omics have received attention from the research community, the media, and the public alike, largely owing to the advances in scientific understanding that have resulted from ‘omics research. It remains an exciting and fast-paced field of study that is set to continue expanding our knowledge of biological molecules and systems.

Global Market Report: Proteomics

In this article, we discuss the applications of proteomics and its recent developments, along with reviewing the current global market and predicting how the field may evolve in the future.

Lipidomics in Food Science

Effects of Filtered Coffee on Plasma Metabolites

The Role of Metabolomics in Precision Medicine

What is Single-Cell Proteomics?

How do we Radiolabel Proteins?

Global Market Overview: Metabolomics

What is Immunoliposome Therapy?

Metabolomics in Toxicology

An Overview of Protein Localization

Investigating the Evolution of Microbiome Science

Protein Production: Initiation, Elongation and Termination

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What is Pharmacometabolomics?

Compound Identification for Nontargeted Metabolomics

What is Western Blotting?

Protein Biosynthesis

Exploring Biosynthetic Diversity

Role of Proteomics in COVID-19

What are Prions?

Understanding Native Protein Characterization

Compound Identification for Nontargeted Metabolomics

Discovering Misfolded Proteins using Fluorescent Probes

Interpreting Proteomics Data

What is 'Bottom-Up' Proteomics?

What are G-Protein-Coupled Receptors?

Protein Degradability

How are the Metabolome and Proteome Related?

What is Phenomics?

Applications of Bone Proteomics

Importance of Solubility and Lipophilicity in Drug Development

How are Advancements in Mass Spectrometry Impacting Metabolomics Research?

The Steps of Protein Synthesis

The Human Metabolome Project

Studying the Metabolic Pathways Between Tissues

Challenges with Standardization in Lipidomics

Challenges in Environmental Metabolomics

Insight into the Human Proteoform Project

The ‘omics’ Revolution

How is Omics Revolutionizing Cancer Research?

What is Proteomics?

Importance of Blood Serum Calorimetry in Lung Cancer Treatment

Quantifying Protein Diversity: Using DIA-MS to Measure Post-Translational Modifications

Eliminating American Foulbrood using Endolysins

Determining Proteins in Milk Using Dumas Analysis

Cytometric Bead Arrays: A Breakdown of the Technique

An Overview of Quantitative Proteomics

Importance of Lipidomics in Stem Cell Research

To the Bone: How Proteomics is Uncovering the Mysteries of Ancient DNA

Challenges in Metabolomic Fingerprinting

What is Clinical Proteomics?

What Role do Proteins Play in Disease?

What is Phosphoproteomics?

Omics Approaches to Biomarker Analysis

How does the Proteome Differ Between Individuals?

A Guide to Optimizing Protein Design

What is Metabolomics?

Liver Disease Biomarkers

A Beginners Guide to Plasma Proteomics

How have Fluorescent Proteins Transformed Science?

What is the Metabolome?

Combating Counterfeit Green Tea with Metabolomic Profiling

Combating Infectious Diseases Through Computational Protein Design

Pharmacokinetics of Cannabis and its Secondary Metabolites

Environmental Metabolomics

Applications of Peptidomics

Comparison Between Metabolic Target Analysis and Metabolic Profiling

Analyzing Proteomes Using LC-MS/MS

Role of Proteomic Analysis in Skin Regeneration

Role of Applied Omics in Precision Medicine

How Can Proteins Help Organisms to Tell the Time?

Heritability Differences in Metabolic Classes

What is 4D Proteomics?

How to Analyze Macromolecular Protein Complexes

Understanding Neurobiology through Proteins

Combining Proteomics and Genomics to Eliminate Disease

What is Protein Ubiquitylation?

What is Forensic Proteomics?

Ethics in Clinical Proteomics

What is Shotgun Lipidomics?

Using Omics to Harness the Power of Personalized Nutrition

Racial Differences in Protein Biomarkers

Latest Proteomics, Metabolomics and Lipidomics News and Research

Genome-Wide Screening Approach Uncovers Genetic Brakes on Blood Cancer Growth

Australian researchers have used an innovative genome-wide screening approach to identify genes, and their encoded proteins, that play critical roles in the prevention of lymphoma development, revealing new potential treatment targets for these blood cancers.

22 Aug 2025

Ancient Interbreeding Provided Modern Humans with Useful Genetic Variation

A new study provides fresh evidence that ancient interbreeding with archaic human species may have provided modern humans with genetic variation that helped them adapt to new environments as they dispersed across the globe.

22 Aug 2025

Discovery of Lysosomal Vacuolation Mechanism Sheds Light on Aging and Disease

New research, published today in the journal Science, shows how lysosomes - organelles that act like cells' waste disposal system - respond to stress by becoming abnormally bloated, a process called lysosomal vacuolation that is associated with numerous diseases.

22 Aug 2025

Breakthrough Technique Enables Large-Scale Study of Polar and Ionic Metabolites

Researchers from the McCullagh Group in Oxford University's Department of Chemistry have published an innovative method in Nature Protocols today (22 August) that provides comprehensive analysis of metabolites found in cells, tissues and biofluids.

22 Aug 2025

Epigenetic Noise Enables Cells to Shift Identity and Influence Immunity

All cells in the body contain the same DNA, but different cell types express different genes; skin cells express genes for the skin, liver cells express liver genes, and so on.

21 Aug 2025

Computational Modeling Creates a Database for Improved Detection of Designer Drugs

How do you identify something no one has a test for? Designer drugs replicate the effects of known, illicit drugs but evade law enforcement.

21 Aug 2025

How Primary Cilia Shape the Fate of Fat Precursor Cells

Too much fat can be unhealthy: how fat cells, so-called adipocytes, develop, is crucial for the function of the fat tissue.

21 Aug 2025

New Tool Offers Insight Into When Genes Turn On and Off in the Brain

A Yale research team has created a new computer tool that can pinpoint when exactly genes turn on and off over time during brain development - a finding that may one day help doctors identify the optimal window to deploy gene therapy treatments.

20 Aug 2025

New Technology Maps Over 140 Proteins Across Human Tissues

Each organ in the human body contains different types of cells arranged in specific ways.

20 Aug 2025

MIT Researchers Unlock the Hidden Features of Protein Language Models

Within the past few years, models that can predict the structure or function of proteins have been widely used for a variety of biological applications, such as identifying drug targets and designing new therapeutic antibodies.

20 Aug 2025

Feline Dementia May Explain Synapse Loss in Alzheimers

The study uncovers amyloid-beta's role in glial-mediated synapse loss in feline cognitive dysfunction, enhancing understanding of Alzheimer's disease.

20 Aug 2025

New Insights Reveal Bacterial Roots of Key Plant Hormone Enzymes

Terpenoids play vital roles in plant ecology-from repelling pests to attracting pollinators-and are produced by terpene synthases (TPSs) enzymes.

19 Aug 2025

Missing Microexons Disrupt Synapse-Related Proteins in Pediatric Glioma

A new study, led by researchers at Children's Hospital of Philadelphia (CHOP), identified tiny pieces of messenger RNA that are missing in pediatric high-grade glioma tumors but not in normal brain tissues.

19 Aug 2025

Amino Acids as Key Mediators in the Tumor Immune Dialogue

The tumor microenvironment is not just a site of cancer growth—it is a high-stakes metabolic contest where tumor and immune cells vie for limited resources.

19 Aug 2025

New Enzyme Technology Illuminates Hidden Sugar Patterns on Cells

Sugars known as glycans form dense envelopes around cells. But they're often ignored in biological investigations because, unlike DNA, proteins and other cellular components, tools to study them are lacking.

18 Aug 2025

Fruit Fly Courtship Behavior Transferred Through Single Gene Manipulation

Researchers in Japan have genetically transferred a unique courtship behavior from one fruit fly species to another.

18 Aug 2025

New Method Enables Human Cells to Initiate Meiosis Outside the Body

More than one-sixth of adults around the world experience infertility in their lifetime. There is a high unmet need not only for increased access to affordable, high-quality fertility care for those in need but, importantly, also for new biomedical solutions that can address the root causes of infertility.

18 Aug 2025