Proteomics, Metabolomics and Lipidomics

The ‘omics revolution ensued from the surge in genetic sequencing seen in the 1990s as scientists aimed to sequence the whole human genome. Advances in sequencing and analytical technologies allowed for increased efficiency and precision, and an integrated, comprehensive approach to understanding organisms followed.
This approach is termed “’omics” and includes the following fields; genomics, transcriptomics, proteomics, fluxomics, and metabolomics. These fields collectively consider all of their respective constituents.
For example, proteomics is the large-scale study of the entire complement of proteins in cell types or organisms. Unlike it’s predecessors, genomics and transcriptomics, proteomics is more complicated as it involves the consideration of post translational modifications, such as phosphorylation. Proteomics has practical applications in protein networks where the study of ways proteins interact aids the field of systems biology, the computational and mathematical analysis and modeling of complex biological systems. Proteomic technologies can be applied to high-throughput techniques, such as mass spectroscopy.
Over the last 30 years, the ’omics have received attention from the research community, the media, and the public alike, largely owing to the advances in scientific understanding that have resulted from ‘omics research. It remains an exciting and fast-paced field of study that is set to continue expanding our knowledge of biological molecules and systems.

Global Market Report: Proteomics

In this article, we discuss the applications of proteomics and its recent developments, along with reviewing the current global market and predicting how the field may evolve in the future.

A Guide to Optimizing Protein Design

The Steps of Protein Synthesis

Protein Degradability

How does the Proteome Differ Between Individuals?

Eliminating American Foulbrood using Endolysins

Discovering Misfolded Proteins using Fluorescent Probes

How have Fluorescent Proteins Transformed Science?

A Beginners Guide to Plasma Proteomics

What are G-Protein-Coupled Receptors?

What is Protein Ubiquitylation?

Applications of Bone Proteomics

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Omics Approaches to Biomarker Analysis

Insight into the Human Proteoform Project

How to Analyze Macromolecular Protein Complexes

What is Forensic Proteomics?

Pharmacokinetics of Cannabis and its Secondary Metabolites

Understanding Native Protein Characterization

Importance of Solubility and Lipophilicity in Drug Development

Importance of Lipidomics in Stem Cell Research

What is Phenomics?

How are Advancements in Mass Spectrometry Impacting Metabolomics Research?

Racial Differences in Protein Biomarkers

Applications of Peptidomics

Combating Infectious Diseases Through Computational Protein Design

Comparison Between Metabolic Target Analysis and Metabolic Profiling

Understanding Neurobiology through Proteins

What is Phosphoproteomics?

Global Market Overview: Metabolomics

Metabolomics in Toxicology

What is Single-Cell Proteomics?

Combining Proteomics and Genomics to Eliminate Disease

An Overview of Quantitative Proteomics

What is Proteomics?

Effects of Filtered Coffee on Plasma Metabolites

Studying the Metabolic Pathways Between Tissues

The Role of Metabolomics in Precision Medicine

Compound Identification for Nontargeted Metabolomics

Environmental Metabolomics

What Role do Proteins Play in Disease?

Challenges in Metabolomic Fingerprinting

What is Immunoliposome Therapy?

How do we Radiolabel Proteins?

Lipidomics in Food Science

Determining Proteins in Milk Using Dumas Analysis

Interpreting Proteomics Data

What is Shotgun Lipidomics?

Combating Counterfeit Green Tea with Metabolomic Profiling

Importance of Blood Serum Calorimetry in Lung Cancer Treatment

Exploring Biosynthetic Diversity

Challenges in Environmental Metabolomics

What are Prions?

What is the Metabolome?

Analyzing Proteomes Using LC-MS/MS

Investigating the Evolution of Microbiome Science

What is Western Blotting?

To the Bone: How Proteomics is Uncovering the Mysteries of Ancient DNA

Protein Biosynthesis

Protein Production: Initiation, Elongation and Termination

Cytometric Bead Arrays: A Breakdown of the Technique

Using Omics to Harness the Power of Personalized Nutrition

Compound Identification for Nontargeted Metabolomics

What is Pharmacometabolomics?

How is Omics Revolutionizing Cancer Research?

What is Clinical Proteomics?

Liver Disease Biomarkers

Ethics in Clinical Proteomics

The Human Metabolome Project

An Overview of Protein Localization

What is 4D Proteomics?

Quantifying Protein Diversity: Using DIA-MS to Measure Post-Translational Modifications

Role of Applied Omics in Precision Medicine

What is 'Bottom-Up' Proteomics?

What is Metabolomics?

Heritability Differences in Metabolic Classes

The ‘omics’ Revolution

How Can Proteins Help Organisms to Tell the Time?

How are the Metabolome and Proteome Related?

Challenges with Standardization in Lipidomics

Role of Proteomic Analysis in Skin Regeneration

Role of Proteomics in COVID-19

Latest Proteomics, Metabolomics and Lipidomics News and Research

New Understanding of Brain Circuitry Genes Opens Door for Targeted OCD Therapies

A Rutgers-led international team co-authored a study, which was published in Nature Neuroscience, revealing 36 genes significantly increasing the risk for obsessive-compulsive disorder (OCD) and chronic tic disorders. This research offers the most comprehensive biological insight into the development of these conditions and potential future treatments.

4 Sep 2026

Historic Parchment Unlocks Ancient Genetic History of Sheeppox Virus

Some of Europe's most well-known historic manuscripts, including the York Gospels, have proven to be biological time capsules for uncovering the 3,500-year history of the sheeppox virus (SPPV).

4 Sep 2026

Genetic Prediction Tools May Misjudge Mutation Risks, Study Finds

When a patient has their DNA read, it gets compared against a reference version of the human genome. It allows geneticists and rare disease experts to look at a list of places where the patient's DNA differs.

4 Sep 2026

Many Misfolded Proteins Manage to Evade the Cellular Maintenance Crew

As proteins are made in a cell, they are folded into the 3-D structure that allows them to work, but sometimes this process can go wrong.

4 Sep 2026

Fruit Fly Egg Chambers Reveal Secrets of Collective Cell Movement

Scientists have long wondered how cells that are organized into sheets begin to move together to form organs, especially when the sheets form closed, sphere-like surfaces and tissues with no edges to direct motion.

3 Sep 2026

Study Reveals Hidden Mutational Process in Colorectal Cancer

The discovery of SBS111 in colorectal cancer offers new perspectives on mutational processes and DNA repair, emphasizing its significance in tumor biology.

3 Sep 2026

AI-Designed Protein Vehicle Enables Lower RNA Dosing While Maximizing Therapeutic Protein Expression

Researchers at Helmholtz Munich and TUM have developed Synthetic Transfer Vehicles (STVs), an entirely new class of RNA transporters. To do so, they combined naturally occurring protein building blocks with synthetic protein structures designed using generative AI.

3 Sep 2026

Scientists Identify Dark Genome Library Containing Over Thirty Thousand Chimeric mRNAs

For decades, scientists have understood that each of the roughly 20,000 genes in the human body carries the instructions for a single kind of protein.

3 Sep 2026

Optical Metabolic Imaging Profiles Single-Cell Metabolic Fitness in Blood Without Dye Labeling

A routine blood sample contains a diverse collection of immune cells that can reveal important clues about health and disease. These cells, known as peripheral blood mononuclear cells (PBMCs), are widely used to study infections, autoimmune disorders, cancer, and the immune system's response to treatment.

3 Sep 2026

Unexpected Mechanism Shows Muscle Cells Limit Rather Than Drive Membrane Growth

Every movement we make, from blinking to sprinting, depends on the ability of muscle fibers to contract in a rapid and coordinated way. Achieving this precision requires an intricate internal membrane network known as the transverse tubule, or T-tubule, system.

3 Sep 2026

Study Reveals How Fungal Enzymes and Clotting Proteins Clog Human Airways

Asthma affects more than 300 million people worldwide, and while many can control their symptoms with inhaled steroid medications, about 10% develop a more severe form that does not respond well to these treatments. This steroid-resistant asthma is one of the most difficult forms of the disease to manage.

3 Sep 2026

New Platform Links Dysfunctional Biomolecular Condensates to Microcephaly and Neurodevelopment

When you add drops of oil to water, the oil and water remain separate. Within cells, biological molecules cluster together in a similar way, separating themselves from the rest of the cell. And while they don't have a membrane, they are their own distinct compartments.

3 Sep 2026

Researchers Unlock Key Potassium Channel That Controls Plant Stalk Elongation

Potassium (K) is one of the three essential nutrients for plants. It plays a critical role in a wide range of processes, including cell growth, photosynthesis, and regulation of water balance. Plants take up K from the soil and circulate it throughout their bodies via molecules called K+ channels.

3 Sep 2026

UNC Researcher Wins Mathers Foundation Grant to Study T-Cell Metabolism

Jessica Thaxton, PhD, MsCR, associate professor in the Department of Cell Biology and Physiology at the UNC School of Medicine and co-leader of the Cancer Cell Biology Research Program at UNC Lineberger Comprehensive Cancer Center, has been awarded a prestigious $700,000 grant from the Mathers Foundation to support research into the role of the endoplasmic reticulum in T-cell metabolism and cancer development.

2 Sep 2026