Proteomics, Metabolomics and Lipidomics

The ‘omics revolution ensued from the surge in genetic sequencing seen in the 1990s as scientists aimed to sequence the whole human genome. Advances in sequencing and analytical technologies allowed for increased efficiency and precision, and an integrated, comprehensive approach to understanding organisms followed.
This approach is termed “’omics” and includes the following fields; genomics, transcriptomics, proteomics, fluxomics, and metabolomics. These fields collectively consider all of their respective constituents.
For example, proteomics is the large-scale study of the entire complement of proteins in cell types or organisms. Unlike it’s predecessors, genomics and transcriptomics, proteomics is more complicated as it involves the consideration of post translational modifications, such as phosphorylation. Proteomics has practical applications in protein networks where the study of ways proteins interact aids the field of systems biology, the computational and mathematical analysis and modeling of complex biological systems. Proteomic technologies can be applied to high-throughput techniques, such as mass spectroscopy.
Over the last 30 years, the ’omics have received attention from the research community, the media, and the public alike, largely owing to the advances in scientific understanding that have resulted from ‘omics research. It remains an exciting and fast-paced field of study that is set to continue expanding our knowledge of biological molecules and systems.

Global Market Report: Proteomics

In this article, we discuss the applications of proteomics and its recent developments, along with reviewing the current global market and predicting how the field may evolve in the future.

Investigating the Evolution of Microbiome Science

Interpreting Proteomics Data

What is Shotgun Lipidomics?

A Beginners Guide to Plasma Proteomics

Protein Production: Initiation, Elongation and Termination

Comparison Between Metabolic Target Analysis and Metabolic Profiling

Understanding Native Protein Characterization

How does the Proteome Differ Between Individuals?

An Overview of Quantitative Proteomics

Discovering Misfolded Proteins using Fluorescent Probes

How are Advancements in Mass Spectrometry Impacting Metabolomics Research?

See more featured articles »

How to Analyze Macromolecular Protein Complexes

What is Pharmacometabolomics?

The ‘omics’ Revolution

Protein Degradability

Exploring Biosynthetic Diversity

Role of Proteomics in COVID-19

Challenges in Metabolomic Fingerprinting

What are Prions?

What is the Metabolome?

Role of Applied Omics in Precision Medicine

Importance of Solubility and Lipophilicity in Drug Development

Effects of Filtered Coffee on Plasma Metabolites

An Overview of Protein Localization

Racial Differences in Protein Biomarkers

Ethics in Clinical Proteomics

Analyzing Proteomes Using LC-MS/MS

What is Protein Ubiquitylation?

Challenges in Environmental Metabolomics

Compound Identification for Nontargeted Metabolomics

Determining Proteins in Milk Using Dumas Analysis

Using Omics to Harness the Power of Personalized Nutrition

Liver Disease Biomarkers

Compound Identification for Nontargeted Metabolomics

Lipidomics in Food Science

A Guide to Optimizing Protein Design

Importance of Blood Serum Calorimetry in Lung Cancer Treatment

Pharmacokinetics of Cannabis and its Secondary Metabolites

What is Western Blotting?

Protein Biosynthesis

Heritability Differences in Metabolic Classes

How do we Radiolabel Proteins?

Combating Infectious Diseases Through Computational Protein Design

What is 4D Proteomics?

Eliminating American Foulbrood using Endolysins

What is Immunoliposome Therapy?

Cytometric Bead Arrays: A Breakdown of the Technique

Metabolomics in Toxicology

How are the Metabolome and Proteome Related?

What is Proteomics?

How Can Proteins Help Organisms to Tell the Time?

Studying the Metabolic Pathways Between Tissues

The Role of Metabolomics in Precision Medicine

What is Single-Cell Proteomics?

What is Forensic Proteomics?

Combating Counterfeit Green Tea with Metabolomic Profiling

Applications of Bone Proteomics

Combining Proteomics and Genomics to Eliminate Disease

Insight into the Human Proteoform Project

Importance of Lipidomics in Stem Cell Research

How is Omics Revolutionizing Cancer Research?

The Human Metabolome Project

What are G-Protein-Coupled Receptors?

Challenges with Standardization in Lipidomics

To the Bone: How Proteomics is Uncovering the Mysteries of Ancient DNA

The Steps of Protein Synthesis

What is Phosphoproteomics?

Role of Proteomic Analysis in Skin Regeneration

Quantifying Protein Diversity: Using DIA-MS to Measure Post-Translational Modifications

Applications of Peptidomics

What is Clinical Proteomics?

What Role do Proteins Play in Disease?

How have Fluorescent Proteins Transformed Science?

Global Market Overview: Metabolomics

Environmental Metabolomics

Omics Approaches to Biomarker Analysis

Understanding Neurobiology through Proteins

What is Phenomics?

What is Metabolomics?

What is 'Bottom-Up' Proteomics?

Latest Proteomics, Metabolomics and Lipidomics News and Research

Researchers Develop High-Throughput Technique to Decode T-Cell Receptors

Studying T cells, the immune cells most responsible for responding to infections and cancers, just received a significant boost in the form of a new technique from St. Jude Children's Research Hospital.

25 Nov 2025

Old Blood Stem Cells Regain Regenerative Capacity Through Lysosomal Intervention

Researchers at the Icahn School of Medicine at Mount Sinai have discovered how to reverse aging in blood-forming stem cells in mice by correcting defects in the stem cell's lysosomes.

25 Nov 2025

New Technique Reveals Synaptic Vesicle Dynamics in Living Brain Tissue

Researchers at Johns Hopkins Medicine say they have used a "zap-and-freeze" technology to watch hard-to-see brain cell communications in living brain tissue from mice and humans.

25 Nov 2025

Ribosome Collisions Activate Key Stress Signaling Mechanisms in Cells

LMU researchers uncover the mechanism by which ribosomes raise alarms in the cell.

25 Nov 2025

Targeting Rhoa to Restore Function in Hematopoietic Stem Cells

Aging is defined as the deterioration of function overtime, and it is one of the main risk factors for numerous chronic diseases.

25 Nov 2025

Novel Mechanism for Epigenetic Patterning in Plants

Every cell within an organism shares an identical genetic blueprint. Their distinct identities stem from epigenetics—precise chemical markers that dictate gene expression.

24 Nov 2025

Senescent Blood Vessel Cells Drive the Development of Metabolic Disorders

Investigators from the Center for Advanced Gerotherapeutics at Cedars-Sinai found that aged blood vessel cells play a key role in the development of metabolic disorders, including diabetes.

24 Nov 2025

Optogenetic Tool Uncovers Key Role of Mechanical Forces in Early Embryonic Development

Only two weeks after fertilization, the first sign of the formation of the 3 axes of the human body (head/tail, ventral/dorsal, and right/left) begins to appear.

24 Nov 2025

Discovery Offers a Potential Way to Boost Tissue Resident Memory T Cell Numbers

We owe a lot to tissue resident memory T cells (TRM). These specialized immune cells are among the body's first responders to disease.

24 Nov 2025

New Tool Maps Microbial Activity to Transform Gut Health Research

The gut microbiome is made up of trillions of microbes that play a vital role in keeping us healthy.  A disturbance in the balance of these microbes can contribute to a variety of health conditions, such as inflammatory bowel disease (IBD).

22 Nov 2025

Cancer Cells Survive Treatment and Regrow by Hijacking Cell Death Enzyme

The emergence of cancer drug resistance remains one of the most pressing problems in cancer care and there is a critical need to devise approaches to mitigate it.

22 Nov 2025

Innovative Sensor Enables Live Observation of DNA Repair in Living Cells

Cancer research, drug safety testing and ageing biology may all gain a major boost from a new fluorescent sensor developed at Utrecht University.

22 Nov 2025

Bacteriophages Facilitate the Survival of Lactic Acid Bacteria in Kimchi Fermentation

The World Institute of Kimchi (President: Hae Choon Chang), a government-funded research institute under the Ministry of Science and ICT, has confirmed in a new study that bacteriophages, which were previously considered a 'nuisance' during the process of food fermentation, actually play the role of key helpers that facilitate the survival of lactic acid bacteria (LAB).

21 Nov 2025

New Multi-Target CAR-T Cells Eradicate Glioblastoma in Preclinical Models

With a five-year survival rate of less than 5%, glioblastoma is one of the most aggressive types of brain cancer.

21 Nov 2025

New Cloaked CRISPR Technology Reveals Hidden Gene Targets for Cancer Metastasis

The immune system plays a crucial role in fighting tumors and metastases. Consequently, it is decisive to conduct cancer research in mouse models with an immune system that is as natural as possible – which is easier said than done.

21 Nov 2025

Cyanobacteria Change Their Genetic Activity After Sunset

Cyanobacteria, also referred to as blue-green algae, are found globally in diverse forms, encompassing both single-celled organisms and filamentous chains.

21 Nov 2025

Novel Active Substance Drives Cancer Cells Toward Self Destruction

A new active substance attacks a key protein in tumor cells, leading to complete degradation. In cell experiments, this caused cancer cells to lose their protection and die.

20 Nov 2025

Chaperone-Shielding Mechanism Regulates Protein Glycosylation

Proteins are often called the building blocks of cells, but even those building blocks need to be built. One of the most important steps in the process of building proteins is glycosylation, when sugar molecules (glycans) are attached to the maturing protein.

20 Nov 2025