Proteomics, Metabolomics and Lipidomics

The ‘omics revolution ensued from the surge in genetic sequencing seen in the 1990s as scientists aimed to sequence the whole human genome. Advances in sequencing and analytical technologies allowed for increased efficiency and precision, and an integrated, comprehensive approach to understanding organisms followed.
This approach is termed “’omics” and includes the following fields; genomics, transcriptomics, proteomics, fluxomics, and metabolomics. These fields collectively consider all of their respective constituents.
For example, proteomics is the large-scale study of the entire complement of proteins in cell types or organisms. Unlike it’s predecessors, genomics and transcriptomics, proteomics is more complicated as it involves the consideration of post translational modifications, such as phosphorylation. Proteomics has practical applications in protein networks where the study of ways proteins interact aids the field of systems biology, the computational and mathematical analysis and modeling of complex biological systems. Proteomic technologies can be applied to high-throughput techniques, such as mass spectroscopy.
Over the last 30 years, the ’omics have received attention from the research community, the media, and the public alike, largely owing to the advances in scientific understanding that have resulted from ‘omics research. It remains an exciting and fast-paced field of study that is set to continue expanding our knowledge of biological molecules and systems.

Global Market Report: Proteomics

In this article, we discuss the applications of proteomics and its recent developments, along with reviewing the current global market and predicting how the field may evolve in the future.

What are Prions?

Global Market Overview: Metabolomics

What is Pharmacometabolomics?

What is Single-Cell Proteomics?

Omics Approaches to Biomarker Analysis

What Role do Proteins Play in Disease?

An Overview of Protein Localization

Discovering Misfolded Proteins using Fluorescent Probes

Importance of Blood Serum Calorimetry in Lung Cancer Treatment

Using Omics to Harness the Power of Personalized Nutrition

Heritability Differences in Metabolic Classes

See more featured articles »

Applications of Bone Proteomics

Understanding Neurobiology through Proteins

What is Phosphoproteomics?

Liver Disease Biomarkers

Metabolomics in Toxicology

Protein Production: Initiation, Elongation and Termination

Racial Differences in Protein Biomarkers

What is Forensic Proteomics?

Comparison Between Metabolic Target Analysis and Metabolic Profiling

What is 'Bottom-Up' Proteomics?

To the Bone: How Proteomics is Uncovering the Mysteries of Ancient DNA

Role of Proteomic Analysis in Skin Regeneration

What is Proteomics?

Determining Proteins in Milk Using Dumas Analysis

How are the Metabolome and Proteome Related?

Role of Applied Omics in Precision Medicine

Eliminating American Foulbrood using Endolysins

Insight into the Human Proteoform Project

Lipidomics in Food Science

What is Phenomics?

Combating Infectious Diseases Through Computational Protein Design

The Human Metabolome Project

What is Protein Ubiquitylation?

Compound Identification for Nontargeted Metabolomics

What is Western Blotting?

The Role of Metabolomics in Precision Medicine

Quantifying Protein Diversity: Using DIA-MS to Measure Post-Translational Modifications

How have Fluorescent Proteins Transformed Science?

How does the Proteome Differ Between Individuals?

Importance of Solubility and Lipophilicity in Drug Development

Effects of Filtered Coffee on Plasma Metabolites

How is Omics Revolutionizing Cancer Research?

What is the Metabolome?

Investigating the Evolution of Microbiome Science

Environmental Metabolomics

Combating Counterfeit Green Tea with Metabolomic Profiling

Studying the Metabolic Pathways Between Tissues

Ethics in Clinical Proteomics

The Steps of Protein Synthesis

Challenges in Metabolomic Fingerprinting

How Can Proteins Help Organisms to Tell the Time?

A Beginners Guide to Plasma Proteomics

Exploring Biosynthetic Diversity

How are Advancements in Mass Spectrometry Impacting Metabolomics Research?

Applications of Peptidomics

What is Clinical Proteomics?

Challenges with Standardization in Lipidomics

A Guide to Optimizing Protein Design

What is Metabolomics?

The ‘omics’ Revolution

Importance of Lipidomics in Stem Cell Research

What is Immunoliposome Therapy?

Analyzing Proteomes Using LC-MS/MS

Interpreting Proteomics Data

Challenges in Environmental Metabolomics

How do we Radiolabel Proteins?

What is 4D Proteomics?

Protein Degradability

How to Analyze Macromolecular Protein Complexes

What are G-Protein-Coupled Receptors?

Understanding Native Protein Characterization

Combining Proteomics and Genomics to Eliminate Disease

Compound Identification for Nontargeted Metabolomics

Role of Proteomics in COVID-19

Protein Biosynthesis

An Overview of Quantitative Proteomics

Pharmacokinetics of Cannabis and its Secondary Metabolites

Cytometric Bead Arrays: A Breakdown of the Technique

What is Shotgun Lipidomics?

Latest Proteomics, Metabolomics and Lipidomics News and Research

New Protein Superfamily Redefines Bacterial Interactions

A newly identified bacterial protein, PopA, reveals complex interactions in bacteria, challenging existing models of membrane protein formation.

9 Jul 2025

New Software Boosts Genome Editing Accuracy for Genetic Therapies

This innovative software, CRISPRware, optimizes guide RNA design for genome editing, supporting research on genetic disorders and uncharacterized peptides.

9 Jul 2025

Improved Bacterial Rubisco Offers Hope for Enhancing Plant Photosynthesis

During photosynthesis, an enzyme called rubisco catalyzes a key reaction - the incorporation of carbon dioxide into organic compounds to create sugars.

8 Jul 2025

Obesity-Related Cognitive Deficits Improved Through Astrocyte Modulation

Fatty diets and obesity affect the structure and function of astrocytes, the star-shaped brain cells located in the striatum, a brain region involved in the perception of pleasure generated by food consumption.

8 Jul 2025

Cryo-EM Uncovers How Tiny Protein Enzyme Precisely Trims tRNA

To build proteins, cells rely on a molecule called transfer RNA, or tRNA. tRNAs act like protein-building couriers, where they read the genetic instructions from messenger RNA, mRNA, and deliver the right amino acids to ribosomes, the cell's protein-making factories.

8 Jul 2025

Mediterranean Bacteria Offer New Weapon Against Mosquito-Borne Diseases

Mosquito-borne diseases kill more than 700,000 people every year, according to the World Health Organization, and the mosquitos that spread the disease are difficult to control.

8 Jul 2025

Reinvigorating T Cells Offers Hope for More Effective Cancer Immunotherapy

CD8⁺ T cells are the immune system's frontline warriors, charged with detecting and eliminating cancer cells. But in the hostile and chronic environment of tumors, these cells often falter.

8 Jul 2025

Scientists Discover Unique Bacterial Protein That Traps Membrane Lipids

Scientists have identified a new type of protein in bacteria that could change our understanding of how these organisms interact with their environments.

8 Jul 2025

New AI Tool Illuminates Bacterial Impact on Body Chemistry

Gut bacteria are well-known for playing an important role in a variety of health issues. However, their quantity and variety are immense, as are the ways in which they interact with the body’s chemistry and with one another.

7 Jul 2025

Aligned Stem Cell Sheets Show Boosted Healing Potential

A new way to grow stem cells may help them release more of the signaling proteins they use to repair tissue, potentially improving future treatments.

4 Jul 2025

Breakthrough Method Rapidly Generates Lung Repair Cells From Fibroblasts

Researchers in Japan have successfully generated lung cells similar to alveolar epithelial type 2 (AT2) cells from mouse embryonic fibroblasts without using stem cell technology.

4 Jul 2025

New Multi Omics Database Advances Chrysanthemum Research and Breeding

The Asteraceae family boasts more than 25,000 species, with chrysanthemums ranking among its most iconic and economically valuable members. Having been cultivated for over three millennia in China and beyond, these plants hold deep cultural, medicinal, and horticultural significance.

4 Jul 2025

Study Links Cell Surface Receptor Pairing to Proper Embryonic Body Shape

During animal development, cells divide and arrange themselves in a coordinated way, eventually forming the embryo.

4 Jul 2025

Small Genetic Change in Humans Weakens Immune Attack on Solid Tumors

New research from UC Davis Comprehensive Cancer Center has uncovered an evolutionary change that may explain why certain immune cells in humans are less effective at fighting solid tumors compared to non-human primates.

4 Jul 2025

Uncovering the Gut Virome's Role in Health and Disease

The human gut is home to trillions of microbes, yet scientific understanding has largely focused on bacteria, leaving the virome—the community of viruses—relatively uncharted.

4 Jul 2025

Flavoproteins Become Built-in Sensors for Studying Cellular Processes

Cornell researchers have found a new and potentially more accurate way to see what proteins are doing inside living cells - using the cells' own components as built-in sensors.

3 Jul 2025

Animal-Free 3D Fat-Immune Cell Model to Study Inflammation

Researchers developed a human adipocyte-macrophage co-culture model in GG hydrogels to study adipose tissue inflammation and test anti-inflammatory strategies.

3 Jul 2025

Combining AI with Robotics and Synthetic Biology to Improve Industrial Enzymes

By combining artificial intelligence with automated robotics and synthetic biology, researchers at the University of Illinois Urbana-Champaign have dramatically improved performance of two important industrial enzymes - and created a user-friendly, fast process to improve many more.

2 Jul 2025

Mapping Thousands of Conserved Gene Groups Across Grasses

A new computational biology pipeline has mapped out over 13,000 groups of protein-coding genes conserved across grasses, offering a powerful tool for researchers investigating gene function in these economically and ecologically vital species.

2 Jul 2025

New Clues Reveal How Multicellularity Evolved in Early Animals

Animals, from worms and sponges to jellyfish and whales, contain anywhere from a few thousand to tens of trillions of nearly genetically identical cells.

2 Jul 2025