Proteomics, Metabolomics and Lipidomics

The ‘omics revolution ensued from the surge in genetic sequencing seen in the 1990s as scientists aimed to sequence the whole human genome. Advances in sequencing and analytical technologies allowed for increased efficiency and precision, and an integrated, comprehensive approach to understanding organisms followed.
This approach is termed “’omics” and includes the following fields; genomics, transcriptomics, proteomics, fluxomics, and metabolomics. These fields collectively consider all of their respective constituents.
For example, proteomics is the large-scale study of the entire complement of proteins in cell types or organisms. Unlike it’s predecessors, genomics and transcriptomics, proteomics is more complicated as it involves the consideration of post translational modifications, such as phosphorylation. Proteomics has practical applications in protein networks where the study of ways proteins interact aids the field of systems biology, the computational and mathematical analysis and modeling of complex biological systems. Proteomic technologies can be applied to high-throughput techniques, such as mass spectroscopy.
Over the last 30 years, the ’omics have received attention from the research community, the media, and the public alike, largely owing to the advances in scientific understanding that have resulted from ‘omics research. It remains an exciting and fast-paced field of study that is set to continue expanding our knowledge of biological molecules and systems.

Global Market Report: Proteomics

In this article, we discuss the applications of proteomics and its recent developments, along with reviewing the current global market and predicting how the field may evolve in the future.

What is Shotgun Lipidomics?

Importance of Blood Serum Calorimetry in Lung Cancer Treatment

An Overview of Quantitative Proteomics

Lipidomics in Food Science

Studying the Metabolic Pathways Between Tissues

A Beginners Guide to Plasma Proteomics

What is Protein Ubiquitylation?

Effects of Filtered Coffee on Plasma Metabolites

Metabolomics in Toxicology

What is Pharmacometabolomics?

What Role do Proteins Play in Disease?

See more featured articles »

How Can Proteins Help Organisms to Tell the Time?

The Human Metabolome Project

Interpreting Proteomics Data

Discovering Misfolded Proteins using Fluorescent Probes

The ‘omics’ Revolution

Combining Proteomics and Genomics to Eliminate Disease

Understanding Neurobiology through Proteins

Using Omics to Harness the Power of Personalized Nutrition

What are G-Protein-Coupled Receptors?

How do we Radiolabel Proteins?

Applications of Bone Proteomics

What is Immunoliposome Therapy?

What are Prions?

How have Fluorescent Proteins Transformed Science?

Role of Proteomics in COVID-19

An Overview of Protein Localization

Importance of Lipidomics in Stem Cell Research

Compound Identification for Nontargeted Metabolomics

Ethics in Clinical Proteomics

What is Single-Cell Proteomics?

What is Phosphoproteomics?

Environmental Metabolomics

Cytometric Bead Arrays: A Breakdown of the Technique

Importance of Solubility and Lipophilicity in Drug Development

What is Proteomics?

What is Phenomics?

The Role of Metabolomics in Precision Medicine

How are the Metabolome and Proteome Related?

Insight into the Human Proteoform Project

Applications of Peptidomics

Protein Biosynthesis

What is Clinical Proteomics?

What is Metabolomics?

Exploring Biosynthetic Diversity

Challenges in Environmental Metabolomics

Global Market Overview: Metabolomics

Combating Counterfeit Green Tea with Metabolomic Profiling

Role of Applied Omics in Precision Medicine

Investigating the Evolution of Microbiome Science

Determining Proteins in Milk Using Dumas Analysis

Eliminating American Foulbrood using Endolysins

What is the Metabolome?

What is 4D Proteomics?

What is Western Blotting?

A Guide to Optimizing Protein Design

What is 'Bottom-Up' Proteomics?

Omics Approaches to Biomarker Analysis

What is Forensic Proteomics?

Protein Production: Initiation, Elongation and Termination

Protein Degradability

How does the Proteome Differ Between Individuals?

Challenges in Metabolomic Fingerprinting

Quantifying Protein Diversity: Using DIA-MS to Measure Post-Translational Modifications

Understanding Native Protein Characterization

Liver Disease Biomarkers

Racial Differences in Protein Biomarkers

Compound Identification for Nontargeted Metabolomics

Analyzing Proteomes Using LC-MS/MS

Role of Proteomic Analysis in Skin Regeneration

Comparison Between Metabolic Target Analysis and Metabolic Profiling

Challenges with Standardization in Lipidomics

How to Analyze Macromolecular Protein Complexes

How is Omics Revolutionizing Cancer Research?

Heritability Differences in Metabolic Classes

How are Advancements in Mass Spectrometry Impacting Metabolomics Research?

Combating Infectious Diseases Through Computational Protein Design

To the Bone: How Proteomics is Uncovering the Mysteries of Ancient DNA

The Steps of Protein Synthesis

Pharmacokinetics of Cannabis and its Secondary Metabolites

Latest Proteomics, Metabolomics and Lipidomics News and Research

Molecular Switch Found to Control Single-Celled to Multicellular Transitions

Scientists at Nagoya University in Japan have identified the genes that allow an organism to switch between living as single cells and forming multicellular structures.

8 Jan 2026

New Molecules Harness Cellular Recycling to Eliminate Cancer's Immune Shield IDO1

Cells have a remarkable housekeeping system: proteins that are no longer needed, defective, or potentially harmful are labeled with a molecular "tag" and dismantled in the cellular recycling machinery.

8 Jan 2026

Synthetic Biology and Metabolic Engineering Drive Microbial L-Tryptophan Biomanufacturing

This review synthesizes progress in pathway optimization, regulatory rewiring, and microbial cell factory design that has driven L-Trp titers to industrially relevant levels while enabling the biosynthesis of downstream products ranging from neurotransmitters and plant hormones to dyes and complex alkaloids.

8 Jan 2026

USU Researchers Discover CRISPR Cas12a3's Potential for Viral Protein Inhibition

Across all domains of life, immune defenses foil invading viruses by making it impossible for the viruses to replicate. Most known CRISPR systems target invading pathogens' DNA and chop it up to disable and modify genes, heading off infections at the (cellular) pass.

8 Jan 2026

Mitochondria Transfer Eases Chronic Nerve Pain

For millions living with nerve pain, even a light touch can feel unbearable. Scientists have long suspected that damaged nerve cells falter because their energy factories known as mitochondria don't function properly.

8 Jan 2026

Turning Human Fat into Insulin-Producing Organoids That Reverse Diabetes

By preserving fat tissue architecture, researchers created organoids that restore insulin function, paving the way for advancements in diabetes treatment.

8 Jan 2026

Identifying Molecules That Activate and Inhibit Key Protein Function

Researchers at Northwestern University have discovered a concealed molecular "control switch" within a protein that plays a crucial role in the body's ability to perceive taste, regulate blood sugar, and protect the gut.

7 Jan 2026

Microneedle Patches May Unlock Safer, Localized Cancer Immunotherapy

This review highlights the potential of natural polysaccharide microneedles in cancer immunotherapy, focusing on localized treatment and immune activation.

7 Jan 2026

Blocking Retinoic Acid Pathway Improves Dendritic Cell Anti-Tumor Function

Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by which a metabolic derivative of vitamin A-all-trans retinoic acid-compromises both the body's normal anti-cancer immune response and, in a different context, the efficacy of a promising type of cancer vaccine.

6 Jan 2026

Hidden Molecular "Control Switch" Uncovered Inside TRPM5 Protein

Northwestern University scientists have uncovered a hidden molecular "control switch" inside a protein that helps the body sense taste, control blood sugar and defend the gut.

6 Jan 2026

Aging Alters a Common Set of RNA Splicing and Processing Genes Across Tissues

A new research paper featured as the cover of Volume 17, Issue 12 of Aging-US was published on December 22, 2025, titled "A combination of differential expression and network connectivity analyses identifies a common set of RNA splicing and processing genes altered with age across human tissues."

6 Jan 2026

Study Resolves Ancient Genome Duplication History of Flowering Plants

Angiosperms, also known as flowering plants, represent the most diverse group of seed plants, and their origin and evolution have long been a central question in plant evolutionary biology.

5 Jan 2026

Scientists Develop Noise Controller to Tame Random Cell Behavior

Why does cancer sometimes recur after chemotherapy? Why do some bacteria survive antibiotic treatment? In many cases, the answer appears to lie not in genetic differences, but in biological noise - random fluctuations in molecular activity that occur even among genetically identical cells.

5 Jan 2026

Interferon Response in Female Brains Linked to Alzheimer's Progression

More than seven million Americans have Alzheimer's disease, and two-thirds of them are women, according to the Alzheimer's Association. The O'Banion Lab at the Del Monte Institute for Neuroscience at the University of Rochester has long been studying this disease and is looking more closely at the differences between male and female brains.

30 Dec 2025

Mitochondrial Protein That “Erases” Huntington’s Aggregates

DGIST has made a groundbreaking announcement: a research team, under the guidance of professors Jiwon Um and Jaewon Ko, has achieved a global first by elucidating the function of ‘ClpB.’

29 Dec 2025

Researchers Find Enzyme That Controls Fat Production, Offering New Drug Target

Obesity is a global epidemic and a major cause of morbidity and mortality because it increases the risk for comorbidities, including heart disease and fatty liver disease (MASLD). Rates of these disorders have risen as the world increasingly adopts energy-dense diets and sedentary lifestyles.

24 Dec 2025

Genetic Factor "Fru" Influences Bees' Cooperative Food-Seeking Behavior

A team of biologists from Heinrich Heine University Düsseldorf (HHU), along with researchers from Bochum and Paris, has uncovered a genetic component underlying intricate social behaviors in bees.

24 Dec 2025

UT Southwestern Researchers Design Tau Protein to Combat Neurodegenerative Diseases

A designer version of the tau protein, developed by a team led by UT Southwestern Medical Center researchers, maintains its biological function while resisting aggregation, a pathological trait linked to neurodegenerative diseases called tauopathies. These findings, reported in Structure, could lead to new treatments for conditions including Alzheimer's disease, frontotemporal dementia, chronic traumatic encephalopathy (CTE), and progressive supranuclear palsy.

24 Dec 2025

Kinetic Traps Explain Differences in GPCR Drug Efficacy

G-protein coupled receptors (GPCRs) are proteins triggered by ligands (protein-binding chemicals) from outside cells to transmit signals inside the cell.

23 Dec 2025

Passive Adaptation Balances Protein Synthesis and Degradation in Cells

Every cell depends on proteins to function and stay healthy. These proteins are made inside the cell from amino acids but cannot simply accumulate inside the cell forever.

23 Dec 2025