Proteomics, Metabolomics and Lipidomics

The ‘omics revolution ensued from the surge in genetic sequencing seen in the 1990s as scientists aimed to sequence the whole human genome. Advances in sequencing and analytical technologies allowed for increased efficiency and precision, and an integrated, comprehensive approach to understanding organisms followed.
This approach is termed “’omics” and includes the following fields; genomics, transcriptomics, proteomics, fluxomics, and metabolomics. These fields collectively consider all of their respective constituents.
For example, proteomics is the large-scale study of the entire complement of proteins in cell types or organisms. Unlike it’s predecessors, genomics and transcriptomics, proteomics is more complicated as it involves the consideration of post translational modifications, such as phosphorylation. Proteomics has practical applications in protein networks where the study of ways proteins interact aids the field of systems biology, the computational and mathematical analysis and modeling of complex biological systems. Proteomic technologies can be applied to high-throughput techniques, such as mass spectroscopy.
Over the last 30 years, the ’omics have received attention from the research community, the media, and the public alike, largely owing to the advances in scientific understanding that have resulted from ‘omics research. It remains an exciting and fast-paced field of study that is set to continue expanding our knowledge of biological molecules and systems.

Global Market Report: Proteomics

In this article, we discuss the applications of proteomics and its recent developments, along with reviewing the current global market and predicting how the field may evolve in the future.

Metabolomics in Toxicology

Protein Production: Initiation, Elongation and Termination

Omics Approaches to Biomarker Analysis

The ‘omics’ Revolution

What is Metabolomics?

What is Clinical Proteomics?

A Guide to Optimizing Protein Design

How does the Proteome Differ Between Individuals?

Discovering Misfolded Proteins using Fluorescent Probes

What is Single-Cell Proteomics?

Role of Applied Omics in Precision Medicine

See more featured articles »

How do we Radiolabel Proteins?

Determining Proteins in Milk Using Dumas Analysis

Applications of Bone Proteomics

Challenges with Standardization in Lipidomics

Challenges in Environmental Metabolomics

Effects of Filtered Coffee on Plasma Metabolites

Comparison Between Metabolic Target Analysis and Metabolic Profiling

How are the Metabolome and Proteome Related?

Role of Proteomics in COVID-19

How have Fluorescent Proteins Transformed Science?

What is Phenomics?

Importance of Solubility and Lipophilicity in Drug Development

How to Analyze Macromolecular Protein Complexes

Understanding Neurobiology through Proteins

Studying the Metabolic Pathways Between Tissues

Importance of Lipidomics in Stem Cell Research

Liver Disease Biomarkers

How are Advancements in Mass Spectrometry Impacting Metabolomics Research?

What is 'Bottom-Up' Proteomics?

The Human Metabolome Project

How Can Proteins Help Organisms to Tell the Time?

To the Bone: How Proteomics is Uncovering the Mysteries of Ancient DNA

Interpreting Proteomics Data

Challenges in Metabolomic Fingerprinting

Protein Degradability

Eliminating American Foulbrood using Endolysins

Ethics in Clinical Proteomics

An Overview of Quantitative Proteomics

What is Shotgun Lipidomics?

Exploring Biosynthetic Diversity

Combining Proteomics and Genomics to Eliminate Disease

Heritability Differences in Metabolic Classes

What is Pharmacometabolomics?

What are Prions?

A Beginners Guide to Plasma Proteomics

Analyzing Proteomes Using LC-MS/MS

Compound Identification for Nontargeted Metabolomics

Using Omics to Harness the Power of Personalized Nutrition

What are G-Protein-Coupled Receptors?

The Role of Metabolomics in Precision Medicine

Cytometric Bead Arrays: A Breakdown of the Technique

Protein Biosynthesis

What is 4D Proteomics?

Environmental Metabolomics

Importance of Blood Serum Calorimetry in Lung Cancer Treatment

Combating Counterfeit Green Tea with Metabolomic Profiling

Combating Infectious Diseases Through Computational Protein Design

Role of Proteomic Analysis in Skin Regeneration

Understanding Native Protein Characterization

What is Western Blotting?

What is the Metabolome?

Quantifying Protein Diversity: Using DIA-MS to Measure Post-Translational Modifications

What is Phosphoproteomics?

What is Forensic Proteomics?

Insight into the Human Proteoform Project

What is Immunoliposome Therapy?

Racial Differences in Protein Biomarkers

Investigating the Evolution of Microbiome Science

What is Proteomics?

The Steps of Protein Synthesis

Compound Identification for Nontargeted Metabolomics

Lipidomics in Food Science

What Role do Proteins Play in Disease?

Pharmacokinetics of Cannabis and its Secondary Metabolites

What is Protein Ubiquitylation?

How is Omics Revolutionizing Cancer Research?

An Overview of Protein Localization

Applications of Peptidomics

Global Market Overview: Metabolomics

Latest Proteomics, Metabolomics and Lipidomics News and Research

Visualizing Real-Time DNA Transcription in a Living Mouse

DNA can be regarded as an extensive library that contains all genetic information. Cells do not utilize this information simultaneously.

30 Jan 2026

Cellular Garbage Collector Shields Neurons From Alzheimer’s Damage

Researchers at UC San Francisco have identified a hazardous waste collector in the brain that disposes of the toxic clumps of tau protein that can lead to dementia.

29 Jan 2026

Natural Molecular Brake Prevents Uncontrolled DNA Replication in Cells

For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a cell divides – which they need to do constantly. Without this process, we would die.

29 Jan 2026

Unraveling the “Dark Energy” Found in the Structural Protein Universe

Astronomers use the term dark energy to refer to energy in the universe that is unaccounted for by ordinary matter but necessary to explain cosmology.

28 Jan 2026

Understanding the Complex Biosynthetic Pathway of O-Mannose Glycans in the Brain

Gifu University scientists have uncovered how a brain-specific enzyme reshapes protein-linked sugar chains to facilitate the formation of complex glycans essential for normal brain function.

28 Jan 2026

Advanced 3D Tumor Organoids Reveal How Glioblastoma Responds to Immunotherapy

UCLA scientists have developed advanced miniature 3D tumor organoid models that make it possible to study glioblastoma tumors in a setting that closely mirrors the human brain, shedding light on how the aggressive cancer interacts with surrounding brain cells and the immune system to become more invasive and resistant to therapy.

28 Jan 2026

Using a Powerful Technology to Track Body's Most Elusive Proteins

What can a single molecule in just one of the body's cells reveal about a person's health? Quite a lot if you can find it. Cedars-Sinai investigators are doing just that.

28 Jan 2026

Scientists Discover Self-Repair Mechanism of Spindle Microtubules

Every second, millions of cells in your body divide in two. In the space of an hour, they duplicate their DNA and grow a web of protein fibers around it called a spindle.

28 Jan 2026

Expanding CRISPR to Tackle Incurable Skin Diseases

Gene-editing techniques such as CRISPR have enabled new treatments for previously incurable diseases. Researchers at the University of British Columbia are now expanding those capabilities to include the skin for the first time.

28 Jan 2026

Blood protein test helps spot hidden cancers in patients with vague symptoms

Plasma protein profiling offers a promising tool for cancer risk stratification in patients with non-specific symptoms, potentially reducing diagnostic delays.

28 Jan 2026

AI-Designed CytoTape Records Cellular Events Over Time With High Resolution

Unraveling the mysteries of how biological organisms function begins with understanding the molecular interactions within and across large cell populations.

27 Jan 2026

Melbourne Scientists Use AI to Tame CRISPR

Last year a ten-month old baby in the US was the first person in the world to have their rare genetic disease effectively cured through the use of CRISPR gene editing technology.

27 Jan 2026

Gut Bacteria Use Protein Injection to Influence Human Immune System

Bacteria in the human gut can directly deliver proteins into human cells, actively shaping immune responses.

27 Jan 2026

Novel Epigenetic Regulator Enhances Downy Mildew Resistance in Brassica rapa

Downy mildew is a major constraint on Brassica crop production worldwide, especially during early developmental stages when plants are highly vulnerable to infection.

27 Jan 2026

MYC Gene's Dual Role in Cancer Growth and Immune Suppression

The cancer gene MYC camouflages tumors by suppressing alarm signals that normally activate the immune system.

24 Jan 2026

New Method Designs Highly Active and Stable Enzymes

Enzymes with specific functions are becoming increasingly important in industry, medicine and environmental protection.

24 Jan 2026

Protein Translation Enzyme Governs Macrophage Maturation and Tissue Homeostasis

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health found that an enzyme involved in protein translation is essential for circulating immune cells, called monocytes, to mature into tissue-resident macrophages, a specialized population of immune cells that maintain organ health by clearing dead cells and debris.

24 Jan 2026

Why the Brain Never Stops Trying to Replace Myelin-Producing Cells

Researchers from Johns Hopkins Medicine, utilizing mouse models, reveal that oligodendrocyte precursor cells differentiate at a consistent, extensive rate throughout adulthood.

23 Jan 2026

Cytomegalovirus can Hijack a Central 'Traffic Controller' for Immune Cells

In a major scientific breakthrough, researchers from Monash University and the Lions Eye Institute have discovered a tissue protein that acts as a central 'traffic controller' for immune cells and can be hijacked by a virus to weaken immune responses.

22 Jan 2026