Proteomics, Metabolomics and Lipidomics

The ‘omics revolution ensued from the surge in genetic sequencing seen in the 1990s as scientists aimed to sequence the whole human genome. Advances in sequencing and analytical technologies allowed for increased efficiency and precision, and an integrated, comprehensive approach to understanding organisms followed.
This approach is termed “’omics” and includes the following fields; genomics, transcriptomics, proteomics, fluxomics, and metabolomics. These fields collectively consider all of their respective constituents.
For example, proteomics is the large-scale study of the entire complement of proteins in cell types or organisms. Unlike it’s predecessors, genomics and transcriptomics, proteomics is more complicated as it involves the consideration of post translational modifications, such as phosphorylation. Proteomics has practical applications in protein networks where the study of ways proteins interact aids the field of systems biology, the computational and mathematical analysis and modeling of complex biological systems. Proteomic technologies can be applied to high-throughput techniques, such as mass spectroscopy.
Over the last 30 years, the ’omics have received attention from the research community, the media, and the public alike, largely owing to the advances in scientific understanding that have resulted from ‘omics research. It remains an exciting and fast-paced field of study that is set to continue expanding our knowledge of biological molecules and systems.

Global Market Report: Proteomics

In this article, we discuss the applications of proteomics and its recent developments, along with reviewing the current global market and predicting how the field may evolve in the future.

How Can Proteins Help Organisms to Tell the Time?

What is Metabolomics?

Role of Proteomic Analysis in Skin Regeneration

What is Phenomics?

Liver Disease Biomarkers

Investigating the Evolution of Microbiome Science

A Beginners Guide to Plasma Proteomics

Ethics in Clinical Proteomics

What is Protein Ubiquitylation?

Environmental Metabolomics

An Overview of Protein Localization

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Protein Production: Initiation, Elongation and Termination

To the Bone: How Proteomics is Uncovering the Mysteries of Ancient DNA

The Steps of Protein Synthesis

Determining Proteins in Milk Using Dumas Analysis

Combining Proteomics and Genomics to Eliminate Disease

Challenges in Environmental Metabolomics

Global Market Overview: Metabolomics

Applications of Peptidomics

Importance of Solubility and Lipophilicity in Drug Development

The Role of Metabolomics in Precision Medicine

What Role do Proteins Play in Disease?

Cytometric Bead Arrays: A Breakdown of the Technique

How does the Proteome Differ Between Individuals?

Compound Identification for Nontargeted Metabolomics

What is Shotgun Lipidomics?

Omics Approaches to Biomarker Analysis

Insight into the Human Proteoform Project

What is Single-Cell Proteomics?

Eliminating American Foulbrood using Endolysins

How are the Metabolome and Proteome Related?

Role of Applied Omics in Precision Medicine

Challenges in Metabolomic Fingerprinting

Metabolomics in Toxicology

Understanding Native Protein Characterization

Effects of Filtered Coffee on Plasma Metabolites

Analyzing Proteomes Using LC-MS/MS

Interpreting Proteomics Data

What is Clinical Proteomics?

How do we Radiolabel Proteins?

Importance of Blood Serum Calorimetry in Lung Cancer Treatment

How to Analyze Macromolecular Protein Complexes

Protein Degradability

The Human Metabolome Project

Importance of Lipidomics in Stem Cell Research

An Overview of Quantitative Proteomics

What is the Metabolome?

Protein Biosynthesis

What is Western Blotting?

Studying the Metabolic Pathways Between Tissues

What is 'Bottom-Up' Proteomics?

The ‘omics’ Revolution

What is Proteomics?

Pharmacokinetics of Cannabis and its Secondary Metabolites

How have Fluorescent Proteins Transformed Science?

What is 4D Proteomics?

Applications of Bone Proteomics

Combating Counterfeit Green Tea with Metabolomic Profiling

Heritability Differences in Metabolic Classes

Combating Infectious Diseases Through Computational Protein Design

Comparison Between Metabolic Target Analysis and Metabolic Profiling

Role of Proteomics in COVID-19

What are G-Protein-Coupled Receptors?

Quantifying Protein Diversity: Using DIA-MS to Measure Post-Translational Modifications

Discovering Misfolded Proteins using Fluorescent Probes

What are Prions?

What is Pharmacometabolomics?

What is Forensic Proteomics?

How is Omics Revolutionizing Cancer Research?

A Guide to Optimizing Protein Design

Racial Differences in Protein Biomarkers

Exploring Biosynthetic Diversity

What is Immunoliposome Therapy?

Understanding Neurobiology through Proteins

What is Phosphoproteomics?

How are Advancements in Mass Spectrometry Impacting Metabolomics Research?

Challenges with Standardization in Lipidomics

Compound Identification for Nontargeted Metabolomics

Using Omics to Harness the Power of Personalized Nutrition

Lipidomics in Food Science

Latest Proteomics, Metabolomics and Lipidomics News and Research

Changes in the Activity of KCC2 Protein Influence Reward Learning

A new finding from researchers at Georgetown University Medical Center shows that the learning process of associating cues with rewards can be altered by increased or decreased activity of a specific protein in the brain.

11 Dec 2025

Researchers Elucidate Microtubule-Mediated Cell Signal Transduction

The most diverse functions of a cell in the human body – from cell division and differentiation to motility and programmed cell death – are controlled by signaling proteins within the cell. This includes the immune system and the reading of genetic information.

11 Dec 2025

OIST Study Illuminates Cancer's Avoidance of Cellular Stress Responses

When cell division (mitosis) takes too long, it can be a sign that something is wrong with the cells, for example DNA damage or chromosomal instability.

11 Dec 2025

Scientists Discover First Human DNA-Cutting Enzyme That Responds to Tension

An international research team at the University of Hong Kong has discovered a human protein known as ANKLE1, which is recognized as the first DNA-cutting enzyme (nuclease) in mammals that can detect and respond to physical tension in DNA.

10 Dec 2025

Breaking the Interspecies Immune Barrier to Advance Human Organ Generation

Failure of human pluripotent stem cells (PSCs) to survive when grown with the PSCs of distantly related species occurs because of an innate immune reaction in the nonhuman cells, a study led by UT Southwestern Medical Center researchers suggests.

9 Dec 2025

Restoring Tenascin-C Protein Could Help Prevent Age-Related Muscle Loss

As we age, the muscles we rely on for daily activities tend to become less reliable. With enough decline, even normal movements such as getting out of bed become risky.

8 Dec 2025

Senescent Fibroblasts in the Tumor Niche Rewire Lung Cancer Metabolism and Plasticity

Senescent fibroblasts are aging cells that no longer divide and protect against tumor development. Yet two decades have gone by since cell biologist Judith Campisi, PhD, paradoxically demonstrated that these same cells can promote cancer growth in a laboratory setting.

5 Dec 2025

PLAMseq Revolutionizes Simultaneous Analysis of Genome Proteins and Their Locations

A team from the Andalusian Centre for Molecular Biology and Regenerative Medicine (CABIMER) has developed an innovative technique called PLAMseq (proximity-labelled affinity-purified mass spectrometry plus sequencing) that, for the first time, allows simultaneous analysis of chromatin-associated proteins and their location in the genome in a single experiment.

5 Dec 2025