Proteomics, Metabolomics and Lipidomics

The ‘omics revolution ensued from the surge in genetic sequencing seen in the 1990s as scientists aimed to sequence the whole human genome. Advances in sequencing and analytical technologies allowed for increased efficiency and precision, and an integrated, comprehensive approach to understanding organisms followed.
This approach is termed “’omics” and includes the following fields; genomics, transcriptomics, proteomics, fluxomics, and metabolomics. These fields collectively consider all of their respective constituents.
For example, proteomics is the large-scale study of the entire complement of proteins in cell types or organisms. Unlike it’s predecessors, genomics and transcriptomics, proteomics is more complicated as it involves the consideration of post translational modifications, such as phosphorylation. Proteomics has practical applications in protein networks where the study of ways proteins interact aids the field of systems biology, the computational and mathematical analysis and modeling of complex biological systems. Proteomic technologies can be applied to high-throughput techniques, such as mass spectroscopy.
Over the last 30 years, the ’omics have received attention from the research community, the media, and the public alike, largely owing to the advances in scientific understanding that have resulted from ‘omics research. It remains an exciting and fast-paced field of study that is set to continue expanding our knowledge of biological molecules and systems.

Global Market Report: Proteomics

In this article, we discuss the applications of proteomics and its recent developments, along with reviewing the current global market and predicting how the field may evolve in the future.

How does the Proteome Differ Between Individuals?

Investigating the Evolution of Microbiome Science

Combining Proteomics and Genomics to Eliminate Disease

What is the Metabolome?

Quantifying Protein Diversity: Using DIA-MS to Measure Post-Translational Modifications

Environmental Metabolomics

Determining Proteins in Milk Using Dumas Analysis

Analyzing Proteomes Using LC-MS/MS

Importance of Solubility and Lipophilicity in Drug Development

Understanding Neurobiology through Proteins

Combating Infectious Diseases Through Computational Protein Design

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What are G-Protein-Coupled Receptors?

Eliminating American Foulbrood using Endolysins

Protein Biosynthesis

Applications of Bone Proteomics

How Can Proteins Help Organisms to Tell the Time?

Protein Degradability

The Role of Metabolomics in Precision Medicine

Combating Counterfeit Green Tea with Metabolomic Profiling

Role of Proteomics in COVID-19

Insight into the Human Proteoform Project

To the Bone: How Proteomics is Uncovering the Mysteries of Ancient DNA

What Role do Proteins Play in Disease?

Comparison Between Metabolic Target Analysis and Metabolic Profiling

Exploring Biosynthetic Diversity

Ethics in Clinical Proteomics

What is Immunoliposome Therapy?

What is 4D Proteomics?

How have Fluorescent Proteins Transformed Science?

How is Omics Revolutionizing Cancer Research?

Compound Identification for Nontargeted Metabolomics

What is Clinical Proteomics?

How are Advancements in Mass Spectrometry Impacting Metabolomics Research?

Pharmacokinetics of Cannabis and its Secondary Metabolites

What is Single-Cell Proteomics?

How do we Radiolabel Proteins?

What is Protein Ubiquitylation?

Understanding Native Protein Characterization

What is Metabolomics?

Importance of Lipidomics in Stem Cell Research

Metabolomics in Toxicology

Protein Production: Initiation, Elongation and Termination

The Human Metabolome Project

What is Phosphoproteomics?

Role of Proteomic Analysis in Skin Regeneration

An Overview of Protein Localization

What is 'Bottom-Up' Proteomics?

Racial Differences in Protein Biomarkers

A Guide to Optimizing Protein Design

What are Prions?

Cytometric Bead Arrays: A Breakdown of the Technique

What is Forensic Proteomics?

The ‘omics’ Revolution

Heritability Differences in Metabolic Classes

How to Analyze Macromolecular Protein Complexes

Interpreting Proteomics Data

Studying the Metabolic Pathways Between Tissues

What is Shotgun Lipidomics?

Effects of Filtered Coffee on Plasma Metabolites

Challenges in Metabolomic Fingerprinting

Lipidomics in Food Science

Role of Applied Omics in Precision Medicine

What is Pharmacometabolomics?

How are the Metabolome and Proteome Related?

Challenges in Environmental Metabolomics

Importance of Blood Serum Calorimetry in Lung Cancer Treatment

Applications of Peptidomics

Challenges with Standardization in Lipidomics

What is Western Blotting?

An Overview of Quantitative Proteomics

Compound Identification for Nontargeted Metabolomics

What is Proteomics?

Omics Approaches to Biomarker Analysis

Using Omics to Harness the Power of Personalized Nutrition

What is Phenomics?

Global Market Overview: Metabolomics

A Beginners Guide to Plasma Proteomics

Discovering Misfolded Proteins using Fluorescent Probes

The Steps of Protein Synthesis

Liver Disease Biomarkers

Latest Proteomics, Metabolomics and Lipidomics News and Research

Nanoplastics Accelerate Ovarian Cancer Growth At Real-World Exposure Levels

Research shows polystyrene nanoplastics accelerate ovarian cancer growth by activating CDK4/6 pathways, with Palbociclib offering a potential countermeasure.

19 Nov 2025

Sabotaging T Cell Exhaustion for Cancer Therapy

Like all hardworking things, the cytotoxic T lymphocytes (CTLs) of the immune system charged with detecting and destroying cancer cells tend to get very tired-so much so, in fact, that they can even die from exhaustion.

18 Nov 2025

Neurons and Other Nondividing Cells Respond Differently to CRISPR-Cas9 Gene Editing

The gene editing tool known as CRISPR-Cas9 is changing what's possible for treating a wide range of diseases caused by genetic mutations.

18 Nov 2025

Researchers Discover Molecular Switch That Helps Breast Cancer Cells Survive Stress

Cells are regularly faced with environmental stresses that may damage or destroy them. To survive, they quickly adjust their gene expression to protect themselves.

18 Nov 2025

Blocking a Hidden Tumor Pathway Revives the Immune System

A new study has discovered a molecular signal that tumors exploit to exhaust the T cells meant to destroy them-and how silencing that signal could revive the body's immunity.

18 Nov 2025

New Tool Studies Kinase Activity During DNA Damage

Cornell researchers have developed a powerful new biosensor that reveals, in unprecedented detail, how and where kinases – enzymes that control nearly all cellular processes – turn on and off inside living cells.

14 Nov 2025

Evosep Unveils Open Innovation Initiative to Expand Standardization in Proteomics

Evosep, a global leader in proteomics solutions, is proud to announce a new initiative at HUPO 2025 aimed at solving one of LCMS based proteomics most persistent challenges: sample preparation.

14 Nov 2025

Bringing Accessible NGS-Based Proteomics to Even More Labs

At Olink, our mission has always been clear: to make high-quality proteomics accessible to every lab.

From Olink®- Part of Thermo Fisher Scientific 13 Nov 2025

Animals Evolved Similar Genetic Tools to Conquer Land Across Distant Lineages

Animals from completely different branches of the tree of life such as insects, worms and vertebrates independently evolved similar genetic solutions to survive on land, according to a new study from researchers at the University of Bristol and University of Barcelona.

13 Nov 2025

AlphaSync Brings Continuous Updates to Global Protein Structure Predictions

The shape, or structure, of proteins determines how they work, making it essential for researchers to have access to high-quality structural models.

12 Nov 2025

Rare Stress-Sensitive Neurons Hold the Key to Healthy Brain Blood Flow

While the exact causes of neurodegenerative brain diseases like Alzheimer's and dementia are still largely unknown, researchers have been able to identify a key characteristic in affected brains: reduced blood flow.

12 Nov 2025

Deciphering PARP14's Role in Viral Pathogenesis

Researchers at the University of Kansas have identified that the human gene encoding the protein PARP14 plays a crucial role in regulating interferon, a key component of the body’s innate immune system.

12 Nov 2025

‘Forever chemicals’ build up in British Columbia sea otters

PFAS contamination in British Columbia sea otters underscores urban pollution's effects on marine life and the importance of long-term ecological monitoring.

12 Nov 2025

Inter-Organelle Crosstalk Regulates Protein Biogenesis in Eukaryotic Cells

Janelia researchers have uncovered a novel way that two of the structures inside cells-the endoplasmic reticulum (ER) and lysosomes-coordinate the production of proteins, highlighting how interactions between organelles are important for regulating cellular processes.

11 Nov 2025

Uncovering the Mechanism of Chromosome Congression for Targeted Cancer Therapy

A research team from The University of Osaka, in collaboration with the Massachusetts Institute of Technology, has uncovered a new molecular mechanism underlying chromosome alignment during cell division.

11 Nov 2025

Neanderthal DNA Reveals Secrets of Jaw Development

Every human face is unique, allowing us to distinguish between individuals. We know little about how facial features are encoded in our DNA, but we may be able to learn more about how our faces develop by looking at our ancient relatives, the Neanderthals.

11 Nov 2025

Dual Role of SlNOR and SlNOR-like1 Revealed in Tomato Pollen Development

Successful fertilization in flowering plants depends on healthy pollen development and structural integrity of the pollen wall.

10 Nov 2025

New Genetic Pathway Explains Why Some Citrus Fruits Taste Less Sour

The characteristic sour-sweet balance of citrus fruits is largely defined by citric acid accumulation in the vacuoles of juice sacs.

10 Nov 2025

Human Pangenome Research Opens a New Chapter in Precision Medicine

In May 2023, the Human Pangenome Reference Consortium (HPRC) released the first draft of the human pangenome reference sequence, which integrated genomic data from 47 individuals representing genetic diversity and added 119 million base pairs of euchromatic polymorphic sequences.

10 Nov 2025

Researchers Find "Hidden" Mutations by Tracing Protein Isoforms

Approximately 25 million individuals in the United States are affected by a rare genetic disorder, and a significant number of them face challenges not only due to the absence of effective treatments but also because of insufficient information regarding their condition.

10 Nov 2025