Proteomics, Metabolomics and Lipidomics

The ‘omics revolution ensued from the surge in genetic sequencing seen in the 1990s as scientists aimed to sequence the whole human genome. Advances in sequencing and analytical technologies allowed for increased efficiency and precision, and an integrated, comprehensive approach to understanding organisms followed.
This approach is termed “’omics” and includes the following fields; genomics, transcriptomics, proteomics, fluxomics, and metabolomics. These fields collectively consider all of their respective constituents.
For example, proteomics is the large-scale study of the entire complement of proteins in cell types or organisms. Unlike it’s predecessors, genomics and transcriptomics, proteomics is more complicated as it involves the consideration of post translational modifications, such as phosphorylation. Proteomics has practical applications in protein networks where the study of ways proteins interact aids the field of systems biology, the computational and mathematical analysis and modeling of complex biological systems. Proteomic technologies can be applied to high-throughput techniques, such as mass spectroscopy.
Over the last 30 years, the ’omics have received attention from the research community, the media, and the public alike, largely owing to the advances in scientific understanding that have resulted from ‘omics research. It remains an exciting and fast-paced field of study that is set to continue expanding our knowledge of biological molecules and systems.

Global Market Report: Proteomics

In this article, we discuss the applications of proteomics and its recent developments, along with reviewing the current global market and predicting how the field may evolve in the future.

How are the Metabolome and Proteome Related?

What is Metabolomics?

What is 'Bottom-Up' Proteomics?

Lipidomics in Food Science

How are Advancements in Mass Spectrometry Impacting Metabolomics Research?

Discovering Misfolded Proteins using Fluorescent Probes

What are G-Protein-Coupled Receptors?

Studying the Metabolic Pathways Between Tissues

What Role do Proteins Play in Disease?

Challenges in Metabolomic Fingerprinting

What is Forensic Proteomics?

See more featured articles »

What is Phenomics?

Using Omics to Harness the Power of Personalized Nutrition

How is Omics Revolutionizing Cancer Research?

Environmental Metabolomics

Pharmacokinetics of Cannabis and its Secondary Metabolites

Protein Degradability

Understanding Neurobiology through Proteins

How have Fluorescent Proteins Transformed Science?

Quantifying Protein Diversity: Using DIA-MS to Measure Post-Translational Modifications

Insight into the Human Proteoform Project

To the Bone: How Proteomics is Uncovering the Mysteries of Ancient DNA

Investigating the Evolution of Microbiome Science

Determining Proteins in Milk Using Dumas Analysis

Role of Proteomics in COVID-19

Combating Counterfeit Green Tea with Metabolomic Profiling

Role of Proteomic Analysis in Skin Regeneration

Analyzing Proteomes Using LC-MS/MS

Combining Proteomics and Genomics to Eliminate Disease

Applications of Bone Proteomics

Challenges in Environmental Metabolomics

An Overview of Quantitative Proteomics

A Beginners Guide to Plasma Proteomics

What is Phosphoproteomics?

Combating Infectious Diseases Through Computational Protein Design

What is Single-Cell Proteomics?

Protein Biosynthesis

A Guide to Optimizing Protein Design

What is Pharmacometabolomics?

Challenges with Standardization in Lipidomics

The Human Metabolome Project

Racial Differences in Protein Biomarkers

What is Western Blotting?

Protein Production: Initiation, Elongation and Termination

The Role of Metabolomics in Precision Medicine

What is Proteomics?

Liver Disease Biomarkers

What is Shotgun Lipidomics?

Compound Identification for Nontargeted Metabolomics

What is Clinical Proteomics?

The Steps of Protein Synthesis

Applications of Peptidomics

How do we Radiolabel Proteins?

Exploring Biosynthetic Diversity

The ‘omics’ Revolution

What is Immunoliposome Therapy?

Cytometric Bead Arrays: A Breakdown of the Technique

What are Prions?

What is the Metabolome?

Interpreting Proteomics Data

Metabolomics in Toxicology

Understanding Native Protein Characterization

How Can Proteins Help Organisms to Tell the Time?

Comparison Between Metabolic Target Analysis and Metabolic Profiling

An Overview of Protein Localization

Global Market Overview: Metabolomics

How does the Proteome Differ Between Individuals?

Effects of Filtered Coffee on Plasma Metabolites

Importance of Solubility and Lipophilicity in Drug Development

Role of Applied Omics in Precision Medicine

Eliminating American Foulbrood using Endolysins

Heritability Differences in Metabolic Classes

How to Analyze Macromolecular Protein Complexes

Importance of Lipidomics in Stem Cell Research

What is 4D Proteomics?

What is Protein Ubiquitylation?

Importance of Blood Serum Calorimetry in Lung Cancer Treatment

Omics Approaches to Biomarker Analysis

Ethics in Clinical Proteomics

Compound Identification for Nontargeted Metabolomics

Latest Proteomics, Metabolomics and Lipidomics News and Research

How Cancer Cells Physically Adapt to Survive Within Bodies

Cancer cells that detach from a primary tumor can remain hidden in the body for years in a dormant state, avoiding immune surveillance and waiting until conditions favor the formation of a new tumor elsewhere—a process called metastasis.

16 Jan 2026

A Week of 40-Hz Sound Triggers Long-Lasting Amyloid Changes in Monkeys

Forty-hertz auditory stimulation in aged monkeys doubles CSF amyloid-β levels, offering insights into non-invasive strategies for Alzheimer's disease treatment.

15 Jan 2026

Rare EBV-Driven B Cell Event May Spark Multiple Sclerosis Onset

Autoimmune diseases such as multiple sclerosis arise when the immune system turns against the body itself.

14 Jan 2026

Intelectin-2: A Dual-Action Lectin Fortifies Gut Barrier and Fights Bacteria

The mucosal surfaces that line the body are embedded with defensive molecules that help keep microbes from causing inflammation and infections.

14 Jan 2026

Scientists Identify TRPM4 as Key Molecular Switch Controlling Intestinal Fluid Balance

Although constipation and diarrhea may seem like opposite problems, they both hinge on the same underlying issue: how much fluid moves into the gut. These common issues affect millions of people in the U.S. each year, yet scientists have not fully understood what regulates intestinal fluid balance.

12 Jan 2026

Scientists Discover Tug-of-War Mechanism Driving Bacteria Flagella Direction Switching

Scientists have uncovered a new explanation for how swimming bacteria change direction, providing fresh insight into one of biology's most intensively studied molecular machines.

12 Jan 2026

Population-Specific Proteomic Analysis Advances Precision Medicine for Type 2 Diabetes

Researchers have conducted the most comprehensive analysis to date linking plasma proteins to genetic variation in individuals from continental Africa.

9 Jan 2026

Deep Learning–Based Codon Optimization Framework Boosts Protein Expression in E. coli

By combining Transformer-based sequence modeling with a novel conditional probability strategy, the approach overcomes long-standing trade-offs between maximizing expression metrics and maintaining translational features critical for proper protein folding.

9 Jan 2026

Parallel Molecular Routes Ensure Accurate Centromere Specification During Cell Division

Despite the immense amount of genetic material present in each cell, around three billion base pairs in humans, this material needs to be accurately divided in two and allocated in equal quantities.

9 Jan 2026

Ancient WUS Genes and Expression Thresholds Shape Shoot Regeneration

Unlike animals, plants generate most organs after embryogenesis through stem cell–driven meristems, enabling lifelong growth and regeneration.

9 Jan 2026

Molecular Switch Found to Control Single-Celled to Multicellular Transitions

Scientists at Nagoya University in Japan have identified the genes that allow an organism to switch between living as single cells and forming multicellular structures.

8 Jan 2026

New Molecules Harness Cellular Recycling to Eliminate Cancer's Immune Shield IDO1

Cells have a remarkable housekeeping system: proteins that are no longer needed, defective, or potentially harmful are labeled with a molecular "tag" and dismantled in the cellular recycling machinery.

8 Jan 2026

Synthetic Biology and Metabolic Engineering Drive Microbial L-Tryptophan Biomanufacturing

This review synthesizes progress in pathway optimization, regulatory rewiring, and microbial cell factory design that has driven L-Trp titers to industrially relevant levels while enabling the biosynthesis of downstream products ranging from neurotransmitters and plant hormones to dyes and complex alkaloids.

8 Jan 2026

USU Researchers Discover CRISPR Cas12a3's Potential for Viral Protein Inhibition

Across all domains of life, immune defenses foil invading viruses by making it impossible for the viruses to replicate. Most known CRISPR systems target invading pathogens' DNA and chop it up to disable and modify genes, heading off infections at the (cellular) pass.

8 Jan 2026

Mitochondria Transfer Eases Chronic Nerve Pain

For millions living with nerve pain, even a light touch can feel unbearable. Scientists have long suspected that damaged nerve cells falter because their energy factories known as mitochondria don't function properly.

8 Jan 2026

Turning Human Fat into Insulin-Producing Organoids That Reverse Diabetes

By preserving fat tissue architecture, researchers created organoids that restore insulin function, paving the way for advancements in diabetes treatment.

8 Jan 2026

Identifying Molecules That Activate and Inhibit Key Protein Function

Researchers at Northwestern University have discovered a concealed molecular "control switch" within a protein that plays a crucial role in the body's ability to perceive taste, regulate blood sugar, and protect the gut.

7 Jan 2026

Microneedle Patches May Unlock Safer, Localized Cancer Immunotherapy

This review highlights the potential of natural polysaccharide microneedles in cancer immunotherapy, focusing on localized treatment and immune activation.

7 Jan 2026

Blocking Retinoic Acid Pathway Improves Dendritic Cell Anti-Tumor Function

Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by which a metabolic derivative of vitamin A-all-trans retinoic acid-compromises both the body's normal anti-cancer immune response and, in a different context, the efficacy of a promising type of cancer vaccine.

6 Jan 2026

Hidden Molecular "Control Switch" Uncovered Inside TRPM5 Protein

Northwestern University scientists have uncovered a hidden molecular "control switch" inside a protein that helps the body sense taste, control blood sugar and defend the gut.

6 Jan 2026