Proteomics, Metabolomics and Lipidomics

The ‘omics revolution ensued from the surge in genetic sequencing seen in the 1990s as scientists aimed to sequence the whole human genome. Advances in sequencing and analytical technologies allowed for increased efficiency and precision, and an integrated, comprehensive approach to understanding organisms followed.
This approach is termed “’omics” and includes the following fields; genomics, transcriptomics, proteomics, fluxomics, and metabolomics. These fields collectively consider all of their respective constituents.
For example, proteomics is the large-scale study of the entire complement of proteins in cell types or organisms. Unlike it’s predecessors, genomics and transcriptomics, proteomics is more complicated as it involves the consideration of post translational modifications, such as phosphorylation. Proteomics has practical applications in protein networks where the study of ways proteins interact aids the field of systems biology, the computational and mathematical analysis and modeling of complex biological systems. Proteomic technologies can be applied to high-throughput techniques, such as mass spectroscopy.
Over the last 30 years, the ’omics have received attention from the research community, the media, and the public alike, largely owing to the advances in scientific understanding that have resulted from ‘omics research. It remains an exciting and fast-paced field of study that is set to continue expanding our knowledge of biological molecules and systems.

Global Market Report: Proteomics

In this article, we discuss the applications of proteomics and its recent developments, along with reviewing the current global market and predicting how the field may evolve in the future.

How are the Metabolome and Proteome Related?

What is Proteomics?

What are Prions?

Challenges with Standardization in Lipidomics

What is 4D Proteomics?

Quantifying Protein Diversity: Using DIA-MS to Measure Post-Translational Modifications

Discovering Misfolded Proteins using Fluorescent Probes

A Guide to Optimizing Protein Design

What is Forensic Proteomics?

Interpreting Proteomics Data

Importance of Blood Serum Calorimetry in Lung Cancer Treatment

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What is Clinical Proteomics?

What is the Metabolome?

To the Bone: How Proteomics is Uncovering the Mysteries of Ancient DNA

Ethics in Clinical Proteomics

Role of Proteomic Analysis in Skin Regeneration

How are Advancements in Mass Spectrometry Impacting Metabolomics Research?

Omics Approaches to Biomarker Analysis

The Steps of Protein Synthesis

Comparison Between Metabolic Target Analysis and Metabolic Profiling

What is Shotgun Lipidomics?

Exploring Biosynthetic Diversity

What is Immunoliposome Therapy?

Protein Production: Initiation, Elongation and Termination

Importance of Solubility and Lipophilicity in Drug Development

What is Phosphoproteomics?

How do we Radiolabel Proteins?

Challenges in Environmental Metabolomics

An Overview of Quantitative Proteomics

The Role of Metabolomics in Precision Medicine

Insight into the Human Proteoform Project

What is Phenomics?

Determining Proteins in Milk Using Dumas Analysis

An Overview of Protein Localization

Understanding Native Protein Characterization

Effects of Filtered Coffee on Plasma Metabolites

Environmental Metabolomics

Studying the Metabolic Pathways Between Tissues

What is Protein Ubiquitylation?

Using Omics to Harness the Power of Personalized Nutrition

Analyzing Proteomes Using LC-MS/MS

Protein Biosynthesis

What is Pharmacometabolomics?

What is Western Blotting?

What Role do Proteins Play in Disease?

How Can Proteins Help Organisms to Tell the Time?

Cytometric Bead Arrays: A Breakdown of the Technique

Pharmacokinetics of Cannabis and its Secondary Metabolites

Combating Counterfeit Green Tea with Metabolomic Profiling

What is Single-Cell Proteomics?

Lipidomics in Food Science

Role of Applied Omics in Precision Medicine

How does the Proteome Differ Between Individuals?

Applications of Bone Proteomics

Role of Proteomics in COVID-19

Applications of Peptidomics

Eliminating American Foulbrood using Endolysins

Understanding Neurobiology through Proteins

Compound Identification for Nontargeted Metabolomics

Metabolomics in Toxicology

What are G-Protein-Coupled Receptors?

Heritability Differences in Metabolic Classes

How is Omics Revolutionizing Cancer Research?

A Beginners Guide to Plasma Proteomics

Protein Degradability

How to Analyze Macromolecular Protein Complexes

How have Fluorescent Proteins Transformed Science?

The ‘omics’ Revolution

Investigating the Evolution of Microbiome Science

Challenges in Metabolomic Fingerprinting

Combining Proteomics and Genomics to Eliminate Disease

Global Market Overview: Metabolomics

Liver Disease Biomarkers

What is 'Bottom-Up' Proteomics?

Combating Infectious Diseases Through Computational Protein Design

What is Metabolomics?

Importance of Lipidomics in Stem Cell Research

Racial Differences in Protein Biomarkers

The Human Metabolome Project

Compound Identification for Nontargeted Metabolomics

Latest Proteomics, Metabolomics and Lipidomics News and Research

New Research Reveals Cellular Switches Driving Physical Adaptation in Marine Species

In the animal kingdom, only those who adapt to their environment will survive. This adaptation comes in a wide range of forms, from invisible internal shifts in gene expression to dramatic anatomical changes, such as tadpoles growing legs and transitioning to life on land as frogs.

8 Aug 2026

Mapping Alternative RNA Splice Isoforms to Identify Novel Therapeutic Targets

Proteogenomics represents a transformative approach in cancer research that bridges the gap between genomic alterations and their functional consequences at the protein level.

8 Aug 2026

Research Reevaluates Crucial Microtubule Stabilizing Protein in Dementia Progression

A protein named tau, which has been highly implicated in the world's No. 1 cause of dementia - Alzheimer's disease - and several other neurodegenerative disorders, may spur these diseases in a way that differs greatly from the pathological pathway usually ascribed to it.

7 Aug 2026

Fruit Fly Genetics Explain How Early Embryos Dictate Head Development

One of the most important milestones in the early life of an organism is when the embryo breaks symmetry and arranges itself to form the head (anterior) at one end and tail (posterior) at the other end.

7 Aug 2026

Emerging m6A RNA Biology Explains Brain Vulnerability to Environmental Hazards

A growing understanding of RNA biology is reshaping how scientists view the relationship between environmental toxicants, brain development, and neurodegenerative disease.

7 Aug 2026

Living Organisms Depend on Bacterial Production of Critical Vitamin B12

All living organisms need a little bit of it to form red blood cells and DNA, as well as to build and support brain and nerve cells. But it's hard to come by: Humans don't make it. Animals don't make it. Plants don't make it.

7 Aug 2026

Modulating T Cell Exhaustion Offers Novel Therapeutic Pathways in Transplantation

A comprehensive new review examines the complex role of T cell exhaustion in organ transplantation, highlighting how this dysfunctional immune state can both promote graft tolerance and create vulnerabilities to infection and malignancy.

7 Aug 2026

Localized Biochemical Halos Shield Pancreatic Beta Cells From Rejection

A protein known as interleukin 10 (IL-10) is the lynchpin of a new method to protect transplanted cells from host immune system aggression.

6 Aug 2026

Tireless Stem Cells Drive Continuous Renewal Across High Friction Human Intestines

Digestion is hard on the cells that line the human gut, and they are constantly being shed and replaced. This renewal is driven by a population of tireless stem cells. These stem cells can both replace the various types of intestinal cells that have been lost as well as renew themselves.

6 Aug 2026

Systematic Platform Accelerates Identification of Novel Protein Degradation Drug Candidates

Investigators at Dana-Farber Cancer Institute have developed a platform for systematically discovering molecular glues that could become protein degradation drug candidates.

6 Aug 2026

Shuttling Gene Activating Proteins Through Packed Histones Treats Neurodegenerative Disease

Cells can switch off genes by tightly packaging DNA around proteins called histones.

6 Aug 2026

Newly Identified Protein Prevents T Cells From Destroying Cancer Cells

Researchers at Mayo Clinic have identified a protein that cancer cells use to suppress the body's immune response, a finding that could support the development of new treatments to improve the effectiveness of cancer immunotherapies.

5 Aug 2026

Protein Discovery Sheds Light on Scarring Diseases

UK and US scientists have uncovered an important piece of the puzzle on the signaling pathway that causes damaging scar tissue to build up in the body, raising hopes for future treatments.

5 Aug 2026

Sustained Stretching Reshapes Keratin Cytoskeleton in Epithelial Cells

Prolonged mechanical stress induces a dramatic keratin reorganization, affecting nuclear protection and offering insights into cellular resilience mechanisms.

5 Aug 2026

Macrophages Release Brain Protein Beacon Drawing Nerves Into Breast Tumors

New research from the University of Oklahoma demonstrates how an aggressive form of breast cancer co-opts the body's own immune system to attract nerves that fuel tumor growth.

5 Aug 2026

Malaria Infection Causes Permanent Damage to Resident Splenic CD163 Macrophages

Macrophages formed in the bone marrow can only assume the function of embryonal phagocytes, or "scavenger cells," to a certain degree according to a study by the University of Bonn and the Peter Doherty Institute for Infection and Immunity at the University of Melbourne.

5 Aug 2026