Proteomics, Metabolomics and Lipidomics

The ‘omics revolution ensued from the surge in genetic sequencing seen in the 1990s as scientists aimed to sequence the whole human genome. Advances in sequencing and analytical technologies allowed for increased efficiency and precision, and an integrated, comprehensive approach to understanding organisms followed.
This approach is termed “’omics” and includes the following fields; genomics, transcriptomics, proteomics, fluxomics, and metabolomics. These fields collectively consider all of their respective constituents.
For example, proteomics is the large-scale study of the entire complement of proteins in cell types or organisms. Unlike it’s predecessors, genomics and transcriptomics, proteomics is more complicated as it involves the consideration of post translational modifications, such as phosphorylation. Proteomics has practical applications in protein networks where the study of ways proteins interact aids the field of systems biology, the computational and mathematical analysis and modeling of complex biological systems. Proteomic technologies can be applied to high-throughput techniques, such as mass spectroscopy.
Over the last 30 years, the ’omics have received attention from the research community, the media, and the public alike, largely owing to the advances in scientific understanding that have resulted from ‘omics research. It remains an exciting and fast-paced field of study that is set to continue expanding our knowledge of biological molecules and systems.

Global Market Report: Proteomics

In this article, we discuss the applications of proteomics and its recent developments, along with reviewing the current global market and predicting how the field may evolve in the future.

Ethics in Clinical Proteomics

Lipidomics in Food Science

Protein Production: Initiation, Elongation and Termination

Omics Approaches to Biomarker Analysis

Applications of Peptidomics

What is Phosphoproteomics?

Discovering Misfolded Proteins using Fluorescent Probes

What is Forensic Proteomics?

Eliminating American Foulbrood using Endolysins

The Steps of Protein Synthesis

How is Omics Revolutionizing Cancer Research?

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Using Omics to Harness the Power of Personalized Nutrition

How to Analyze Macromolecular Protein Complexes

Heritability Differences in Metabolic Classes

Cytometric Bead Arrays: A Breakdown of the Technique

A Beginners Guide to Plasma Proteomics

What is Proteomics?

How do we Radiolabel Proteins?

Role of Proteomic Analysis in Skin Regeneration

What is Phenomics?

Pharmacokinetics of Cannabis and its Secondary Metabolites

Effects of Filtered Coffee on Plasma Metabolites

Combating Counterfeit Green Tea with Metabolomic Profiling

To the Bone: How Proteomics is Uncovering the Mysteries of Ancient DNA

Combating Infectious Diseases Through Computational Protein Design

Global Market Overview: Metabolomics

What is Western Blotting?

What is the Metabolome?

Compound Identification for Nontargeted Metabolomics

An Overview of Protein Localization

Studying the Metabolic Pathways Between Tissues

Exploring Biosynthetic Diversity

Challenges with Standardization in Lipidomics

The Role of Metabolomics in Precision Medicine

Liver Disease Biomarkers

How does the Proteome Differ Between Individuals?

An Overview of Quantitative Proteomics

Comparison Between Metabolic Target Analysis and Metabolic Profiling

Analyzing Proteomes Using LC-MS/MS

How are Advancements in Mass Spectrometry Impacting Metabolomics Research?

Role of Proteomics in COVID-19

Investigating the Evolution of Microbiome Science

What is Metabolomics?

Interpreting Proteomics Data

Importance of Blood Serum Calorimetry in Lung Cancer Treatment

What is 4D Proteomics?

What Role do Proteins Play in Disease?

A Guide to Optimizing Protein Design

Importance of Lipidomics in Stem Cell Research

The Human Metabolome Project

What are G-Protein-Coupled Receptors?

What is 'Bottom-Up' Proteomics?

Protein Degradability

Compound Identification for Nontargeted Metabolomics

Protein Biosynthesis

Understanding Native Protein Characterization

Challenges in Metabolomic Fingerprinting

Quantifying Protein Diversity: Using DIA-MS to Measure Post-Translational Modifications

What is Clinical Proteomics?

Combining Proteomics and Genomics to Eliminate Disease

Environmental Metabolomics

Determining Proteins in Milk Using Dumas Analysis

Metabolomics in Toxicology

Importance of Solubility and Lipophilicity in Drug Development

What are Prions?

How Can Proteins Help Organisms to Tell the Time?

What is Shotgun Lipidomics?

What is Single-Cell Proteomics?

What is Protein Ubiquitylation?

What is Pharmacometabolomics?

How are the Metabolome and Proteome Related?

Understanding Neurobiology through Proteins

Challenges in Environmental Metabolomics

The ‘omics’ Revolution

Insight into the Human Proteoform Project

Applications of Bone Proteomics

What is Immunoliposome Therapy?

Role of Applied Omics in Precision Medicine

Racial Differences in Protein Biomarkers

How have Fluorescent Proteins Transformed Science?

Latest Proteomics, Metabolomics and Lipidomics News and Research

Plant Genetics Research Reveals Dynamic and Diverse Centromere Behavior

Cell division is an essential process by which living organisms grow, replenish lost cells, and regenerate dead and damaged tissues.

8 Aug 2025

New RNA Sequencing Technology Uncovers Molecular Drivers of Cellular Differentiation

Researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, have documented their use of a new RNA sequencing technology to uncover molecular drivers of cellular differentiation that could lead to better regenerative therapies.

8 Aug 2025

New Imaging System Reveals Cellular Activity at Unprecedented Depths

Both for research and medical purposes, researchers have spent decades pushing the limits of microscopy to produce ever deeper and sharper images of brain activity, not only in the cortex but also in regions underneath such as the hippocampus.

8 Aug 2025

Integrating Microfluidics and Mass Spectrometry to Unlock Cellular Complexity

Understanding cellular heterogeneity is essential for deciphering the complexities of cellular subpopulations, differentiation processes, and microenvironmental influences.

8 Aug 2025

Mapping T Cell Targets to Fight Coronaviruses and Beyond

Most vaccines are designed to provide immunity against just one pathogen. Vaccines for chicken pox (caused by varicella-zoster virus) were only developed to fight that one disease, for example.

8 Aug 2025

Salk Scientists Use CRISPR to Uncover Microproteins Linked to Obesity

The obesity rate has more than doubled in the last 30 years, affecting more than one billion people worldwide.

8 Aug 2025

Smaller Scale Mutations in HNF1A Gene Nudge Millions Toward Type-2 Diabetes

Mutations in a single gene, HNF1A, are known to cause MODY3, a rare, early onset form of diabetes.

7 Aug 2025

Microglia Replacement Therapy Offers Hope for Genetic Disorders Affecting the Brain

Tay-Sachs and Sandhoff diseases, genetic disorders affecting the brain, have no effective treatment and are typically fatal within the first years of life.

7 Aug 2025

Parkinson’s Gene Mutation Blocks Vital Neuroprotective Signals

GBA1 mutations impair ciliary Hedgehog signaling in Parkinson's disease, reducing neuroprotective factors and highlighting a shared pathogenic pathway.

7 Aug 2025

Ribosome Levels Drop During Early Brain Development

A team led by UT Southwestern Medical Center scientists has identified a specific stage of neurodevelopment when differentiating neural cells produce fewer ribosomes, which are responsible for making proteins.

6 Aug 2025

Uncovering How Cells Precisely Control Protein Production

It's known as biology's central dogma: All living organisms' genetic information is stored in DNA, which is transcribed into RNA, which is translated into proteins that perform nearly all essential tasks in a cell.

6 Aug 2025

Simple Peptides Mimic Natural Protein Protection to Revolutionize Biomolecule Stability

A new study from researchers at the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) reveals that extremely simple peptides can mimic a biological process that protects sensitive proteins from environmental stress.

6 Aug 2025

Case Western Researchers Use Stem Cells to “Shut Off” Nerve Cell Strain

Amyotrophic lateral sclerosis (ALS), sometimes known as Lou Gehrig’s disease, is an incurable neurological disease that affects motor neurons, which are nerve cells in the brain and spinal cord that regulate voluntary muscle movement and breathing.

6 Aug 2025

Prime Editing Reverses Symptoms of Severe Childhood Neurological Disease

Scientists use a precise form of gene editing called prime editing to correct the most common genetic mutations that cause alternating hemiplegia of childhood, a rare and severe neurological disorder that begins in infancy.

From The Jackson Labs 6 Aug 2025

CD276 Antibody Strategy Offers Hope For Immune-Resistant Lung Tumors

The study highlights 8H8_SDIE's role in activating NK cells against NSCLC, offering a new strategy for patients resistant to conventional immunotherapies.

6 Aug 2025

New PCE Systems Enable Precise Genome Engineering Across Kilobase to Megabase Scales

A team of Chinese researchers led by Prof. GAO Caixia from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has developed two new genome editing technologies, known collectively as Programmable Chromosome Engineering (PCE) systems.

5 Aug 2025

Small Protein LptM Plays Key Role in Assembling Protective Outer Membrane in Bacteria

Gram-negative bacteria pose a significant threat to global health due to their high resistance to antibiotics compared to that of Gram-positive bacteria.

5 Aug 2025

Scientists Uncover New Activation Mechanism of the Human Sweet Taste Receptor

Sweet taste receptors are proteins in taste buds that detect sugar and other sweeteners, but the mechanism underlying how they elicit a sweet response has been unclear.

5 Aug 2025

Small Changes in Brain Enzyme May Have Shaped Modern Human Behavior

The evolutionary success of our species may have hinged on minute changes to our brain biochemistry after we diverged from the lineage leading to Neanderthals and Denisovans about half a million years ago.

5 Aug 2025

Hemostatic Dressing Developed for Severe Burn Injuries

A team led by Dr. Chao Zhong and Bolin An of the Chinese Academy of Sciences' Shenzhen Institute of Advanced Technology, along with Dr. Yan Liu of Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, created a novel hemostatic dressing based on bacterial cellulose (BC) that allows for quick and long-lasting bleeding control.

4 Aug 2025