Proteomics, Metabolomics and Lipidomics

The ‘omics revolution ensued from the surge in genetic sequencing seen in the 1990s as scientists aimed to sequence the whole human genome. Advances in sequencing and analytical technologies allowed for increased efficiency and precision, and an integrated, comprehensive approach to understanding organisms followed.
This approach is termed “’omics” and includes the following fields; genomics, transcriptomics, proteomics, fluxomics, and metabolomics. These fields collectively consider all of their respective constituents.
For example, proteomics is the large-scale study of the entire complement of proteins in cell types or organisms. Unlike it’s predecessors, genomics and transcriptomics, proteomics is more complicated as it involves the consideration of post translational modifications, such as phosphorylation. Proteomics has practical applications in protein networks where the study of ways proteins interact aids the field of systems biology, the computational and mathematical analysis and modeling of complex biological systems. Proteomic technologies can be applied to high-throughput techniques, such as mass spectroscopy.
Over the last 30 years, the ’omics have received attention from the research community, the media, and the public alike, largely owing to the advances in scientific understanding that have resulted from ‘omics research. It remains an exciting and fast-paced field of study that is set to continue expanding our knowledge of biological molecules and systems.

Global Market Report: Proteomics

In this article, we discuss the applications of proteomics and its recent developments, along with reviewing the current global market and predicting how the field may evolve in the future.

What is Western Blotting?

What is Pharmacometabolomics?

Eliminating American Foulbrood using Endolysins

Protein Production: Initiation, Elongation and Termination

Pharmacokinetics of Cannabis and its Secondary Metabolites

Combining Proteomics and Genomics to Eliminate Disease

What is Shotgun Lipidomics?

Protein Biosynthesis

Applications of Bone Proteomics

Global Market Overview: Metabolomics

Applications of Peptidomics

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How are Advancements in Mass Spectrometry Impacting Metabolomics Research?

Protein Degradability

What are G-Protein-Coupled Receptors?

Determining Proteins in Milk Using Dumas Analysis

Combating Counterfeit Green Tea with Metabolomic Profiling

How Can Proteins Help Organisms to Tell the Time?

Effects of Filtered Coffee on Plasma Metabolites

Exploring Biosynthetic Diversity

Liver Disease Biomarkers

Role of Proteomic Analysis in Skin Regeneration

Lipidomics in Food Science

Analyzing Proteomes Using LC-MS/MS

How have Fluorescent Proteins Transformed Science?

To the Bone: How Proteomics is Uncovering the Mysteries of Ancient DNA

Ethics in Clinical Proteomics

What is Protein Ubiquitylation?

The Steps of Protein Synthesis

What is Phenomics?

Challenges in Metabolomic Fingerprinting

How are the Metabolome and Proteome Related?

Discovering Misfolded Proteins using Fluorescent Probes

How is Omics Revolutionizing Cancer Research?

Compound Identification for Nontargeted Metabolomics

Omics Approaches to Biomarker Analysis

Importance of Blood Serum Calorimetry in Lung Cancer Treatment

Challenges in Environmental Metabolomics

What is Clinical Proteomics?

What is Proteomics?

What is the Metabolome?

What is Forensic Proteomics?

Interpreting Proteomics Data

The ‘omics’ Revolution

A Beginners Guide to Plasma Proteomics

Understanding Native Protein Characterization

What is 4D Proteomics?

Investigating the Evolution of Microbiome Science

What is Immunoliposome Therapy?

Racial Differences in Protein Biomarkers

Role of Proteomics in COVID-19

What is Phosphoproteomics?

The Role of Metabolomics in Precision Medicine

Importance of Solubility and Lipophilicity in Drug Development

The Human Metabolome Project

Compound Identification for Nontargeted Metabolomics

A Guide to Optimizing Protein Design

What is 'Bottom-Up' Proteomics?

Insight into the Human Proteoform Project

An Overview of Quantitative Proteomics

Environmental Metabolomics

Cytometric Bead Arrays: A Breakdown of the Technique

Using Omics to Harness the Power of Personalized Nutrition

How does the Proteome Differ Between Individuals?

Role of Applied Omics in Precision Medicine

What Role do Proteins Play in Disease?

Studying the Metabolic Pathways Between Tissues

Metabolomics in Toxicology

Comparison Between Metabolic Target Analysis and Metabolic Profiling

What is Single-Cell Proteomics?

How do we Radiolabel Proteins?

What are Prions?

An Overview of Protein Localization

How to Analyze Macromolecular Protein Complexes

Quantifying Protein Diversity: Using DIA-MS to Measure Post-Translational Modifications

Combating Infectious Diseases Through Computational Protein Design

Understanding Neurobiology through Proteins

Challenges with Standardization in Lipidomics

Heritability Differences in Metabolic Classes

Importance of Lipidomics in Stem Cell Research

What is Metabolomics?

Latest Proteomics, Metabolomics and Lipidomics News and Research

New Molecular Map Traces Human Disease Genes Back to LECA

A University of Texas at Austin-led team has reconstructed the most detailed map to date of the molecular machines that carried out the functions of life in an ancient ancestor that gave rise to all complex life on Earth, including us, shedding new light on genetic causes of human diseases.

28 May 2026

OIST Scientists Uncover Key Mechanism Behind Regulated Cell Division

During animal cell division, a highly synchronized and tightly regulated dance of chromosomes takes place, ensuring the chromosomes split correctly into the two cells.

28 May 2026

Molecular Blueprint Shows How Vital Gene Regulation Complexes Form

While scientists have known for over two decades that all cells use a strategy called RNA interference to regulate gene expression, a new study is the first to describe how a specific protein manages the step-by-step process of assembling the molecular complex that performs the regulatory job.

27 May 2026

Extracellular Acidosis Disrupts Internal Transport Systems of Living Cells

A new scientific study led by the Universidad Carlos III de Madrid (UC3M) describes the mechano-chemical mechanism by which the acidity of the cellular environment destabilizes microtubules, the "avenues" that organize internal cellular traffic.

27 May 2026

Structural Discovery Solves Long Standing Mystery in T Cell Biology

Researchers at VIB, Ghent University, and VUB have uncovered how two proteins essential for immune cell development work together at the molecular level.

27 May 2026

Ovarian Cancer Fluid Helps Tumors Evade Cell Death

Ascites in ovarian cancer rewires tumor metabolism, protecting cells from ferroptosis and promoting metastasis, revealing potential therapeutic targets.

27 May 2026

Study Identifies Potential Metabolic Biomarkers for Metastatic Castration-Resistant Tumors

Ceramides-lipid molecules in cells that affect many physiological functions including cell differentiation, migration, and death-and their metabolites have been implicated in the development of cancer and other conditions.

26 May 2026

Researchers Link Brain Extracellular Matrix Deterioration to Postmenopausal Memory Loss

A largely overlooked space between cells in women's brains may hold the key to understanding memory loss tied to estrogen decline after menopause, reports a new preclinical Northwestern Medicine study.

26 May 2026

Genomewide CRISPR Screen Reveals Unexpected Structural Protein Link Behind Chronic Colon Inflammation

Since a landmark 2009 study, researchers have known that a common gut bacterium, Bacteroides fragilis, drives colon tumor formation, potentially leading to colorectal cancer, by secreting a toxin that damages the lining of the colon. But until now, the exact mechanism the toxin uses to latch onto those cells remained a mystery.

25 May 2026

Genetically Engineered Gene Deletions Reveal Unexpected Links Between Ghrelin and Blood Glucose Stability

Hormones influence how we feel - happy, sad or hungry - and profoundly shape how our bodies function and respond to disease.

25 May 2026

Study Connects Lysosomal Lipid Movement Directly to Cellular Growth Signaling

While many American adults are trying to reduce cholesterol levels, certain cancerous tumors have a relentless appetite for the metabolite. Some tumor cells use as much cholesterol as they can access to accelerate their growth beyond the capabilities of normal cells.

25 May 2026

Inflammatory Cytokines Trigger Higher Protein Levels as a Natural Defense Mechanism Against Disease

A new study from researchers at the University of Chicago provides important insight into how the pancreas protects itself during inflammation, pointing to promising new directions for treating pancreatitis.

23 May 2026

Specialized Intative Cells Release Peptide Hormones to Rapidly Signal an Amino Acid Deficiency

Eating is not only about getting enough calories. Animals also need to choose the right nutrients. When the body lacks protein, it must seek essential amino acids - the protein building blocks that cannot be made internally and must come from food.

23 May 2026

Synthetic Biology and Artificial Intelligence Transform the Discovery of Mysterious Orphan Receptors

A new review highlights how synthetic biology, AI, and spatial omics could transform ligand-receptor discovery from one-by-one searches into network-level mapping

23 May 2026

Researchers Use Yeast Sugar Molecules to Extend COVID Vaccine Immunity in Mice

In a new study published in Nature Immunology, researchers at Boston Children's Hospital demonstrated that pairing the original COVID-19 mRNA vaccine with an immune system enhancer, known as an adjuvant, extended the duration of the vaccine's protection in mice from a few months up to two years. The combo also showed a more pronounced response against omicron viral components than the vaccine alone.

23 May 2026

AI Designs Custom Miniproteins to Precisely Control Cell Receptors

G protein-coupled receptors, or GPCRs, sit in the plasma membrane, the boundary that defines the inside and outside of a living cell. They communicate with nearly every physiological process in our bodies - from the ability to see and smell, to sensing of adrenaline, insulin, nutrients and medicines.

22 May 2026

Essential Keratin Guides Embryonic Cell Movement in Developing Zebrafish

Hair, nails, and horns, all made up of keratin, are some of the hardest and most resilient structures in animals. Inside zebrafish cells, keratin plays a distinct role, giving them the strength they need to move together as a coherent tissue while modulating the driving forces behind their movement during early development. But what happens when keratin is missing?

22 May 2026

Scientists Capture Live-Action Footage of Housekeeping Immune Cells Engulfing Melanoma

Scientists at the Garvan Institute of Medical Research have captured, for the first time, 'housekeeping' immune cells actively attacking and engulfing live melanoma cells – a discovery that could change the way we approach treatment for one of Australia's most common and deadly cancers.

22 May 2026

High Protein Levels Bypass Functional BRCA Defenses to Generate Toxic Double-Strand Genomic Breaks

When it comes to cancer, tumor suppressor genes are usually thought of as the "good guys." These genes make proteins that protect and repair DNA in cells.

22 May 2026

Dental Pulp Stem Cell Subsets Triggers Rapid Cellular Senescence and Tooth Decay

With age, teeth get increasingly brittle and susceptible to damage from tooth decay, which can eventually lead to tooth loss. Teeth have an intrinsic capability to regenerate, a process which is driven by dental pulp stem cells (DPSCs) which replenish the dental pulp including the dentin-producing cells called odontoblasts.

22 May 2026