Proteomics, Metabolomics and Lipidomics

The ‘omics revolution ensued from the surge in genetic sequencing seen in the 1990s as scientists aimed to sequence the whole human genome. Advances in sequencing and analytical technologies allowed for increased efficiency and precision, and an integrated, comprehensive approach to understanding organisms followed.
This approach is termed “’omics” and includes the following fields; genomics, transcriptomics, proteomics, fluxomics, and metabolomics. These fields collectively consider all of their respective constituents.
For example, proteomics is the large-scale study of the entire complement of proteins in cell types or organisms. Unlike it’s predecessors, genomics and transcriptomics, proteomics is more complicated as it involves the consideration of post translational modifications, such as phosphorylation. Proteomics has practical applications in protein networks where the study of ways proteins interact aids the field of systems biology, the computational and mathematical analysis and modeling of complex biological systems. Proteomic technologies can be applied to high-throughput techniques, such as mass spectroscopy.
Over the last 30 years, the ’omics have received attention from the research community, the media, and the public alike, largely owing to the advances in scientific understanding that have resulted from ‘omics research. It remains an exciting and fast-paced field of study that is set to continue expanding our knowledge of biological molecules and systems.

Global Market Report: Proteomics

In this article, we discuss the applications of proteomics and its recent developments, along with reviewing the current global market and predicting how the field may evolve in the future.

Challenges in Environmental Metabolomics

What is Phenomics?

Insight into the Human Proteoform Project

What are G-Protein-Coupled Receptors?

How is Omics Revolutionizing Cancer Research?

Heritability Differences in Metabolic Classes

What is Pharmacometabolomics?

The ‘omics’ Revolution

Combating Infectious Diseases Through Computational Protein Design

Importance of Solubility and Lipophilicity in Drug Development

Challenges with Standardization in Lipidomics

See more featured articles »

Applications of Bone Proteomics

Protein Degradability

The Role of Metabolomics in Precision Medicine

Cytometric Bead Arrays: A Breakdown of the Technique

Challenges in Metabolomic Fingerprinting

Understanding Native Protein Characterization

Role of Proteomics in COVID-19

How are the Metabolome and Proteome Related?

What are Prions?

Liver Disease Biomarkers

How Can Proteins Help Organisms to Tell the Time?

What is Shotgun Lipidomics?

What is Forensic Proteomics?

How does the Proteome Differ Between Individuals?

What is Protein Ubiquitylation?

Studying the Metabolic Pathways Between Tissues

How are Advancements in Mass Spectrometry Impacting Metabolomics Research?

How do we Radiolabel Proteins?

An Overview of Protein Localization

Investigating the Evolution of Microbiome Science

To the Bone: How Proteomics is Uncovering the Mysteries of Ancient DNA

Role of Proteomic Analysis in Skin Regeneration

Racial Differences in Protein Biomarkers

Lipidomics in Food Science

What is 'Bottom-Up' Proteomics?

What is Western Blotting?

What Role do Proteins Play in Disease?

A Beginners Guide to Plasma Proteomics

Ethics in Clinical Proteomics

What is Immunoliposome Therapy?

An Overview of Quantitative Proteomics

Analyzing Proteomes Using LC-MS/MS

Effects of Filtered Coffee on Plasma Metabolites

Global Market Overview: Metabolomics

What is Metabolomics?

What is Phosphoproteomics?

Importance of Lipidomics in Stem Cell Research

Protein Biosynthesis

Environmental Metabolomics

The Steps of Protein Synthesis

Quantifying Protein Diversity: Using DIA-MS to Measure Post-Translational Modifications

Compound Identification for Nontargeted Metabolomics

Applications of Peptidomics

Combating Counterfeit Green Tea with Metabolomic Profiling

Using Omics to Harness the Power of Personalized Nutrition

A Guide to Optimizing Protein Design

Interpreting Proteomics Data

Protein Production: Initiation, Elongation and Termination

Eliminating American Foulbrood using Endolysins

Role of Applied Omics in Precision Medicine

Pharmacokinetics of Cannabis and its Secondary Metabolites

What is Clinical Proteomics?

How to Analyze Macromolecular Protein Complexes

Exploring Biosynthetic Diversity

Compound Identification for Nontargeted Metabolomics

What is the Metabolome?

The Human Metabolome Project

Discovering Misfolded Proteins using Fluorescent Probes

What is Single-Cell Proteomics?

Metabolomics in Toxicology

What is Proteomics?

Determining Proteins in Milk Using Dumas Analysis

Comparison Between Metabolic Target Analysis and Metabolic Profiling

Combining Proteomics and Genomics to Eliminate Disease

Importance of Blood Serum Calorimetry in Lung Cancer Treatment

Understanding Neurobiology through Proteins

How have Fluorescent Proteins Transformed Science?

What is 4D Proteomics?

Omics Approaches to Biomarker Analysis

Latest Proteomics, Metabolomics and Lipidomics News and Research

Merck KGaA, Darmstadt, Germany, Agrees to Acquire Bio-Techne, Strengthening Leadership Position in Fast-Growing Life Sciences Markets

Merck KGaA, Darmstadt, Germany, a leading science and technology company, and Bio-Techne Corporation, a Minneapolis-based global provider of life science tools, analytical technologies, and consumables, today entered into a definitive agreement pursuant to which Merck KGaA, Darmstadt, Germany, will, subject to customary closing conditions, acquire Bio-Techne for US$73 per share in cash, representing a total enterprise value of approximately US$11.3 billion (EUR 9.9 billion), a 36% premium to Bio-Techne's one-month volume weighted average trading price.

From Bio-Techne 26 Jun 2026

New Karyoptosis Mechanism Linked to Alzheimer's and Frontotemporal Dementia

Markers of a new mechanism for cell death, called karyoptosis, have been found in brains of patients with Alzheimer's disease and frontotemporal dementia (FTD).

26 Jun 2026

Self-Propelled Actin Structures Drive Shape Changes in Human Cells

Every time a white blood cell engulfs a bacterium, a neuron extends a projection to connect with a neighboring cell, or when a cancer cell forcefully squeezes through tissue to spread, the cell must change its shape to accommodate the movement.

26 Jun 2026

Antibiotics Trigger Accelerated Protein Sharing Among Genetically Identical Bacterial Populations

When bacteria are under antibiotic attack, it is not 'every man for himself.' Researchers at Baylor College of Medicine and colleagues from collaborating institutions have discovered that bacterial populations work as a team to survive antibiotics.

26 Jun 2026

Stanford Researchers Find Dual Protein Mechanism Driving Psoriasis Inflammation

Two proteins with opposing functions orchestrate the development and maintenance of healthy skin, Stanford Medicine researchers have found.

26 Jun 2026

Scientists Decode 3D Structure of Vision Proteins to Fight Blindness

They allow us to see the world in thousands of colors: red strawberries, green leaves, the blue sky.

26 Jun 2026

Scientists Discover Hidden Protein Variant Driving Severe COVID-19 and Lung Fibrosis

A genetic difference carried by nearly one in three people may increase the risk of severe COVID-19 and lung fibrosis by disrupting the function of a previously unknown protein, according to a new study.

25 Jun 2026

Ancient Proteins Uncover Potential Female Burial Site in Homo naledi Population

Scientists have extracted and analyzed the first-ever ancient proteins from the fossils of Homo naledi, revealing a potential all female burial site.

25 Jun 2026

Researchers Discover Molecules Targeting Vital Cell Signaling Proteins

To function normally, nearly every cell in the human body relies on G-protein coupled receptors (GPCRs) to receive and send signals. That's why GPCRs are targeted by roughly one-third of all FDA‑approved drugs.

25 Jun 2026

Novel Cellular Discoveries Offer New Potential Treatment Strategies for Arthritis

Researchers at Hospital for Special Surgery (HSS) have identified a specialized population of immune cells that play a central role in driving abnormal tissue growth in rheumatoid arthritis (RA), offering new insight into disease progression and potential treatment strategies.

25 Jun 2026

Automated Cell-Free Systems Boost Protein Production Performance Five-Fold

A research team led by Professor Joongoo Lee in the Department of Chemical Engineering at POSTECH (Pohang University of Science and Technology) has developed an automated, modular method for assembling reconstituted cell-free systems, which are test-tube systems that can produce proteins outside living cells.

25 Jun 2026

NVIDIA Announces BioNeMo Agent Toolkit — Tools for Agents to Accelerate Scientific Discovery

NVIDIA today announced NVIDIA BioNeMo Agent Toolkit, which provides domain-specific tools and skills for the agentic life sciences era.

From Benchling 25 Jun 2026

Modified Mediterranean Diet Improves Lifespan and Metabolic Health

A plant- and fish-based, low-protein diet paired with small amounts of an amino acid commonly found in eggs, meat and dairy increased healthy lifespan and decreased frailty and fat mass in mice, according to a new USC study published today in the journal Cell Metabolism.

24 Jun 2026

Real-Time Molecular Tool Observes Complex Immune System Changes

A lot of things need to go right on a molecular level for immune cells to launch an adaptive response to an infection.

24 Jun 2026

Immune Pathway Breakthrough Reveals Critical Sex Differences in Female Glioblastoma

Researchers have identified a critical biological difference in how glioblastoma develops in male and female laboratory models, pinpointing an immune pathway that fuels tumor growth only in females.

24 Jun 2026

Study Reveals How Arsenic Pollution Alters Bacterial Metabolism and Detoxification

As arsenic levels increased, bacterial richness and diversity declined, while arsenic-tolerant groups such as Proteobacteria became more abundant. The study also found that bacteria strengthened stress-response pathways, including signal transduction and cell motility, and upregulated arsenic-resistance genes such as arsC2 and arsB.

23 Jun 2026

Cryo-EM Imaging Uncovers the Structure of a Mysterious Molecular "Gate"

How large, fully folded proteins can pass through cell membranes without destroying them has long been one of the open questions in cell biology. Using cryo-electron microscopy (cryo‑EM), Leonid Sazanov and Ziyu Zhao at the Institute of Science and Technology Austria (ISTA) have now uncovered new details about a molecular "gate." Their findings were published in Molecular Cell.

23 Jun 2026

Scientists Discover Hidden Brain Development Signaling Pathway

The cytoskeleton gives cells their shape and helps them move. Researchers at Helmholtz Munich and the Ludwig Maximilian University now show that, in neural stem cells, proteins of the cytoskeleton are also found in the cell nucleus, where they can influence developmental programs.

23 Jun 2026

Scripps Research Identifies Erucamide Molecule as Shield Against Blindness

Many conditions that cause vision loss share a common feature: the gradual breakdown of the retina, the light-sensing tissue at the back of the eye.

23 Jun 2026

Decoding Hidden Metabolic Tissue Crosstalk via Advanced Proteomic Tracking

The body's organs are in constant communication. Fat tissue tells the liver when to store or release energy, the immune system signals localized inflammation, and thousands of proteins carry these messages to organs throughout the body.

23 Jun 2026