Proteomics, Metabolomics and Lipidomics

The ‘omics revolution ensued from the surge in genetic sequencing seen in the 1990s as scientists aimed to sequence the whole human genome. Advances in sequencing and analytical technologies allowed for increased efficiency and precision, and an integrated, comprehensive approach to understanding organisms followed.
This approach is termed “’omics” and includes the following fields; genomics, transcriptomics, proteomics, fluxomics, and metabolomics. These fields collectively consider all of their respective constituents.
For example, proteomics is the large-scale study of the entire complement of proteins in cell types or organisms. Unlike it’s predecessors, genomics and transcriptomics, proteomics is more complicated as it involves the consideration of post translational modifications, such as phosphorylation. Proteomics has practical applications in protein networks where the study of ways proteins interact aids the field of systems biology, the computational and mathematical analysis and modeling of complex biological systems. Proteomic technologies can be applied to high-throughput techniques, such as mass spectroscopy.
Over the last 30 years, the ’omics have received attention from the research community, the media, and the public alike, largely owing to the advances in scientific understanding that have resulted from ‘omics research. It remains an exciting and fast-paced field of study that is set to continue expanding our knowledge of biological molecules and systems.

Global Market Report: Proteomics

In this article, we discuss the applications of proteomics and its recent developments, along with reviewing the current global market and predicting how the field may evolve in the future.

Global Market Overview: Metabolomics

What is Proteomics?

What is Single-Cell Proteomics?

Racial Differences in Protein Biomarkers

Combining Proteomics and Genomics to Eliminate Disease

Using Omics to Harness the Power of Personalized Nutrition

How is Omics Revolutionizing Cancer Research?

Insight into the Human Proteoform Project

Omics Approaches to Biomarker Analysis

The Role of Metabolomics in Precision Medicine

The Human Metabolome Project

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Role of Applied Omics in Precision Medicine

What is Metabolomics?

Challenges with Standardization in Lipidomics

To the Bone: How Proteomics is Uncovering the Mysteries of Ancient DNA

Ethics in Clinical Proteomics

Applications of Peptidomics

How do we Radiolabel Proteins?

What is Clinical Proteomics?

Understanding Native Protein Characterization

What is 'Bottom-Up' Proteomics?

What is Shotgun Lipidomics?

A Beginners Guide to Plasma Proteomics

Lipidomics in Food Science

Protein Biosynthesis

What are Prions?

Challenges in Environmental Metabolomics

Discovering Misfolded Proteins using Fluorescent Probes

Compound Identification for Nontargeted Metabolomics

Combating Infectious Diseases Through Computational Protein Design

What is Forensic Proteomics?

Eliminating American Foulbrood using Endolysins

Environmental Metabolomics

How are the Metabolome and Proteome Related?

Importance of Lipidomics in Stem Cell Research

Interpreting Proteomics Data

What Role do Proteins Play in Disease?

Metabolomics in Toxicology

What is 4D Proteomics?

What is Phosphoproteomics?

Importance of Blood Serum Calorimetry in Lung Cancer Treatment

What is Protein Ubiquitylation?

What is the Metabolome?

Applications of Bone Proteomics

What are G-Protein-Coupled Receptors?

A Guide to Optimizing Protein Design

Determining Proteins in Milk Using Dumas Analysis

Role of Proteomic Analysis in Skin Regeneration

An Overview of Protein Localization

Liver Disease Biomarkers

What is Pharmacometabolomics?

Protein Degradability

Comparison Between Metabolic Target Analysis and Metabolic Profiling

Analyzing Proteomes Using LC-MS/MS

Challenges in Metabolomic Fingerprinting

The Steps of Protein Synthesis

Effects of Filtered Coffee on Plasma Metabolites

How have Fluorescent Proteins Transformed Science?

Compound Identification for Nontargeted Metabolomics

Combating Counterfeit Green Tea with Metabolomic Profiling

Protein Production: Initiation, Elongation and Termination

What is Phenomics?

Importance of Solubility and Lipophilicity in Drug Development

How does the Proteome Differ Between Individuals?

What is Immunoliposome Therapy?

Heritability Differences in Metabolic Classes

Exploring Biosynthetic Diversity

Pharmacokinetics of Cannabis and its Secondary Metabolites

Understanding Neurobiology through Proteins

The ‘omics’ Revolution

How Can Proteins Help Organisms to Tell the Time?

Role of Proteomics in COVID-19

An Overview of Quantitative Proteomics

What is Western Blotting?

How are Advancements in Mass Spectrometry Impacting Metabolomics Research?

Studying the Metabolic Pathways Between Tissues

Quantifying Protein Diversity: Using DIA-MS to Measure Post-Translational Modifications

Investigating the Evolution of Microbiome Science

How to Analyze Macromolecular Protein Complexes

Cytometric Bead Arrays: A Breakdown of the Technique

Latest Proteomics, Metabolomics and Lipidomics News and Research

New Blood Test Could Revolutionize Alzheimer’s Diagnosis

Research confirms the Lumipulse serum p-tau217 assay's effectiveness in diagnosing Alzheimer's, paving the way for accessible blood-based testing in healthcare.

18 Apr 2025

Revealing Noise-Filtering in Basic Circadian Networks

New research has revealed that a simple circadian clock network possesses advanced noise-filtering capabilities, which improves the understanding of how biological circuits maintain accuracy in dynamic environmental contexts.

16 Apr 2025

Study Reveals Muscle Memory at the Protein Level

Researchers have delved into the quantities of thousands of muscle proteins, uncovering a potential new explanation for the phenomenon of muscle memory.

16 Apr 2025

Inherited Genes Play Key Role in Cancer Development

A groundbreaking study has revealed how inherited genetic abnormalities, known as germline variants, play a vital role in the progression of cancer.

16 Apr 2025

ORNL Scientists Develop Fluorescent Biosensor to Track RNA in Plants

Scientists at Oak Ridge National Laboratory have developed a first-ever method of detecting ribonucleic acid, or RNA, inside plant cells using a technique that results in a visible fluorescent signal.

16 Apr 2025

Tumor Recurrence Prediction from Multi-Omics Information by Deep Learning

MULGONET combines deep learning and multi-omics analysis to predict tumor recurrence, addressing interpretability and enhancing cancer prognosis understanding.

16 Apr 2025

Peptide Imitation is the Sincerest Form of Plant Flattery

Industrial farming practices often deplete the soil of important nutrients and minerals, leaving farmers to rely on artificial fertilizers to support plant growth. In fact, fertilizer use has more than quadrupled since the 1960s, but this comes with serious consequences.

16 Apr 2025

Crucial Details in DNA Repair Processes

Researchers at the University of Birmingham have discovered answers that offer detail to explain two distinct DNA repair pathways that have long been debated.

15 Apr 2025

Novel Compound Targets Salmonella's Infection Mechanism

Pathogenic Salmonella strains inject effector proteins into gastrointestinal tract cells, allowing them to infiltrate and grow. Bacteria are often consumed with contaminated food.

15 Apr 2025

How P. syringae Outsmarts Amoeba with Chemical Surveillance and Strikes

Pseudomonas syringae's chemical sensing system allows it to kill amoeba predators, showcasing its evolutionary strategies for survival and plant infection.

14 Apr 2025

Complete Reference Genomes Unlocked for Six Ape Species

Comprehensive reference genomes have now been assembled for six ape species: siamang (a Southeast Asian gibbon), Sumatran orangutan, Bornean orangutan, gorilla, bonobo and chimpanzee.

12 Apr 2025

Unraveling the Mystery of Inefficient Split Inteins in Protein Splicing

Proteins serve as the fundamental components of life, composed of folded peptide chains made up of a sequence of amino acids.

11 Apr 2025

Japanese Researchers Develop New Assay to Detect Epigenetic Toxicity

Chemicals used as food preservatives, flavoring agents, dyes, pesticides, cosmetics, cleaners, and other industrial materials are being increasingly recognized as a health hazard.

11 Apr 2025

Breakthrough Delivery System Advances CRISPR-Based Treatments

A research team from Helmholtz Munich and the Technical University of Munich has developed an advanced delivery system that transports gene-editing tools based on the CRISPR/Cas9 gene-editing system into living cells with significantly greater efficiency than before.

10 Apr 2025

Unraveling the Interaction Between Mitochondrial Proteins HAX1 and CLPB

A recent study published in Magnetic Resonance Letters has revealed for the first time the interaction mechanism between the mitochondrial proteins HAX1 and CLPB, filling the research gap between these two key proteins in the field of structural dynamics and functional association.

10 Apr 2025

New Protein Identified as Regulator of Mitochondrial Calcium Transport

Calcium transport into and out of mitochondria – the powerhouses of cells – is central to cellular energy production and cell death.

9 Apr 2025

QRICH1 Protein Found to Control T Cell Activation in Cancer and Autoimmune Diseases

In a study of the immune systems of mice, scientists at Johns Hopkins Medicine say they have found a new role for a protein, QRICH1, which could become a target for drugs to dial up or down the activation of T cells to fight cancers and autoimmune diseases.

9 Apr 2025

DNA Computing Circuits Move Closer to Real-Time Function Inside Living Cells

A comprehensive review titled "From the Test Tube to the Cell: A Homecoming for DNA Computing Circuits?" published Mar. 4 in Intelligent Computing, a Science Partner Journal, highlights progress in operating DNA computing circuits for operation within living cells.

9 Apr 2025

Placenta-Derived Signals Improve Liver Organoid Size and Function

Organoids, which are designed to mimic human organs, hold promise for both research and treatment;

9 Apr 2025

New Research Further Translates the Language of the Genome

New research has uncovered more about the complexity of human gene regulation by identifying certain sequences of proteins called transcription factors that bind to DNA and regulate the expression of human genes.

9 Apr 2025