Proteomics, Metabolomics and Lipidomics

The ‘omics revolution ensued from the surge in genetic sequencing seen in the 1990s as scientists aimed to sequence the whole human genome. Advances in sequencing and analytical technologies allowed for increased efficiency and precision, and an integrated, comprehensive approach to understanding organisms followed.
This approach is termed “’omics” and includes the following fields; genomics, transcriptomics, proteomics, fluxomics, and metabolomics. These fields collectively consider all of their respective constituents.
For example, proteomics is the large-scale study of the entire complement of proteins in cell types or organisms. Unlike it’s predecessors, genomics and transcriptomics, proteomics is more complicated as it involves the consideration of post translational modifications, such as phosphorylation. Proteomics has practical applications in protein networks where the study of ways proteins interact aids the field of systems biology, the computational and mathematical analysis and modeling of complex biological systems. Proteomic technologies can be applied to high-throughput techniques, such as mass spectroscopy.
Over the last 30 years, the ’omics have received attention from the research community, the media, and the public alike, largely owing to the advances in scientific understanding that have resulted from ‘omics research. It remains an exciting and fast-paced field of study that is set to continue expanding our knowledge of biological molecules and systems.

Global Market Report: Proteomics

In this article, we discuss the applications of proteomics and its recent developments, along with reviewing the current global market and predicting how the field may evolve in the future.

Lipidomics in Food Science

Analyzing Proteomes Using LC-MS/MS

What is Forensic Proteomics?

Importance of Blood Serum Calorimetry in Lung Cancer Treatment

How are the Metabolome and Proteome Related?

Protein Production: Initiation, Elongation and Termination

Role of Proteomic Analysis in Skin Regeneration

Metabolomics in Toxicology

What is Single-Cell Proteomics?

The Steps of Protein Synthesis

What is Western Blotting?

See more featured articles »

What is Proteomics?

Compound Identification for Nontargeted Metabolomics

Ethics in Clinical Proteomics

Understanding Neurobiology through Proteins

Role of Applied Omics in Precision Medicine

Challenges in Metabolomic Fingerprinting

What is Phenomics?

What is Shotgun Lipidomics?

An Overview of Quantitative Proteomics

Environmental Metabolomics

Compound Identification for Nontargeted Metabolomics

Eliminating American Foulbrood using Endolysins

How does the Proteome Differ Between Individuals?

How is Omics Revolutionizing Cancer Research?

What is Metabolomics?

An Overview of Protein Localization

Quantifying Protein Diversity: Using DIA-MS to Measure Post-Translational Modifications

How to Analyze Macromolecular Protein Complexes

Exploring Biosynthetic Diversity

Protein Biosynthesis

Determining Proteins in Milk Using Dumas Analysis

Liver Disease Biomarkers

Comparison Between Metabolic Target Analysis and Metabolic Profiling

What is the Metabolome?

Heritability Differences in Metabolic Classes

What is 4D Proteomics?

Effects of Filtered Coffee on Plasma Metabolites

How are Advancements in Mass Spectrometry Impacting Metabolomics Research?

Combating Infectious Diseases Through Computational Protein Design

Insight into the Human Proteoform Project

Applications of Peptidomics

To the Bone: How Proteomics is Uncovering the Mysteries of Ancient DNA

How do we Radiolabel Proteins?

What are Prions?

Racial Differences in Protein Biomarkers

Using Omics to Harness the Power of Personalized Nutrition

A Beginners Guide to Plasma Proteomics

What is Clinical Proteomics?

Discovering Misfolded Proteins using Fluorescent Probes

Global Market Overview: Metabolomics

Importance of Solubility and Lipophilicity in Drug Development

What is Pharmacometabolomics?

Studying the Metabolic Pathways Between Tissues

What is Protein Ubiquitylation?

Pharmacokinetics of Cannabis and its Secondary Metabolites

What is Immunoliposome Therapy?

Investigating the Evolution of Microbiome Science

The Human Metabolome Project

Role of Proteomics in COVID-19

Omics Approaches to Biomarker Analysis

Combating Counterfeit Green Tea with Metabolomic Profiling

What is Phosphoproteomics?

What Role do Proteins Play in Disease?

Protein Degradability

Importance of Lipidomics in Stem Cell Research

Challenges with Standardization in Lipidomics

The ‘omics’ Revolution

What is 'Bottom-Up' Proteomics?

Combining Proteomics and Genomics to Eliminate Disease

Understanding Native Protein Characterization

How Can Proteins Help Organisms to Tell the Time?

Challenges in Environmental Metabolomics

Cytometric Bead Arrays: A Breakdown of the Technique

How have Fluorescent Proteins Transformed Science?

A Guide to Optimizing Protein Design

Applications of Bone Proteomics

The Role of Metabolomics in Precision Medicine

What are G-Protein-Coupled Receptors?

Interpreting Proteomics Data

Latest Proteomics, Metabolomics and Lipidomics News and Research

Web-Based Platform Facilitates Chemical Structure Queries in Metabolomics

An international team led by researchers at University of California San Diego and University of California, Riverside has developed a free, web‑based platform designed to make public metabolomics data more accessible.

15 May 2026

Animals Adapt Rapidly Through Protein Networks, Not Genes

UT Southwestern Medical Center researchers have discovered a key molecular mechanism that allows animals to adapt to changing environmental conditions without altering their genes – an ability known as phenotypic plasticity.

15 May 2026

Novel RNA Analysis Method Supports Antiviral Drug Discovery

Researchers from A*STAR Genome Institute of Singapore (A*STAR GIS) have developed a new method, called 'sm-PORE-cupine', to study individual RNA molecules and reveal how their structures influence gene regulation, a fundamental process that affects how cells function in health and disease.

15 May 2026

Scientists Discover How DNA Damage Modulates the Tumor Microenvironment for Therapy

Researchers have identified a pathway that triggers an immune response in cells with defective DNA repair.

14 May 2026

Restricted Interaction Peptides Change Shape to Lock Therapy Inside Solid Tumors

Medications are designed to treat diseased tissues while sparing healthy ones, often by attaching the drug to something that helps guide it directly to its target.

14 May 2026

A Possible Brain Fluid Recycling System In Humans

A study shows cerebrospinal fluid circulates in the brain, enhancing waste clearance and offering insights into aging and neurodegenerative disease mechanisms.

14 May 2026

Inherited Genetic Pathways Shape Individual Cancer Risk and Outcomes

Why do two people with the same cancer diagnosis-the same stage, the same cell type, and the same clinical profile-often have completely different outcomes? For decades, scientists have studied acquired mutations in cancer to find answers, but mutations alone explain only part of the story.

12 May 2026

DNA Study Reveals the Personal Pathways Behind Different Tumors

Why do two individuals with the identical cancer diagnosis—the same cell type, the same stage, and the same clinical profile—often experience very different outcomes? Scientists have been researching acquired mutations in cancer for decades in an effort to uncover solutions, but mutations by themselves only account for a part of the problem.

11 May 2026

New Analysis Uncovers Evolutionary Adaptations Within Human Gut Bacteria

The human gut harbors a complex ecosystem of trillions of microorganisms (the microbiome), which influences digestion, the immune system and metabolism.

8 May 2026

New CRISPR System Destroys Diseased Cells With High Precision

A new kind of CRISPR that destroys cells rather than gene editing them has shown potential for killing sick cells while leaving healthy cells untouched.

8 May 2026

Why Women Face a Much Higher Risk of Autoimmune Disease

A recent study has identified biological abnormalities that make the female immune system more likely to mistakenly attack the body's own healthy tissues, providing insight into why women are significantly more likely than men to experience autoimmune diseases.

8 May 2026

Cell Swelling Found to Trigger Inflammatory Immune Responses

As part of the body's first line of defense against foreign invaders, macrophages play an integral role in the innate immune system.

8 May 2026

Scientists Discover Viral Strategy That Disables Bacterial CRISPR Immunity

Bacteria fend off invading viruses with molecular scissors that slice up viral DNA - a system called CRISPR that's become indispensable to gene editing.

8 May 2026

How Genetic Bonuses Help Gut Bacteria Adapt to Industrialization

Billions of microorganisms-primarily bacteria, viruses, and fungi-colonize our gut. This complex community is known as the microbiome.

7 May 2026

UNC Professor Receives Grant to Investigate Origins of the Genetic Code

Over the course of natural history, animals and plants have evolved to adapt to an ever-changing environment and increase the chances of survival. So, too, has our own DNA.

7 May 2026

Tardigrade Proteins Allow Synthetic Cells to Survive Extreme Dehydration

A protein found only in microscopic tardigrades, one that allows them to survive extreme conditions like dehydration, can convey similar durability in synthetic cells, according to new research from University of Michigan Engineering and the University of Chicago Pritzker School of Molecular Engineering.

7 May 2026

New Single-Cell Technique Reveals Why Bacteria Survive Antibiotics

SinBactM's innovative approach to single-bacterium metabolomics reveals distinct metabolic states, enhancing understanding of antibiotic resistance in bacteria.

6 May 2026

Discovery Shows How Plants Prevent Excess Immune Responses

Salicylic acid, the active molecule in aspirin and some acne medications, is a hormone in plants that is essential for immunity, but it's a double-edged sword: Too much can cause autoimmunity and stunt growth.

5 May 2026

Metabolic Pathway Loss Makes Cancer Cells Vulnerable to PARP Drugs

Loss of an enzyme necessary for a process called lipoylation disrupts the way cancer cells copy their DNA, increasing their vulnerability to a class of anticancer drugs known as PARP inhibitors, a study led by UT Southwestern Medical Center researchers shows.

5 May 2026

New Model Explains How Genetic Information Maintains Cellular Order

A Moffitt Cancer Center researcher has introduced a new model that addresses one of biology's most fundamental questions: How does genetic information keep living systems organized and therefore alive?

5 May 2026