Proteomics, Metabolomics and Lipidomics

The ‘omics revolution ensued from the surge in genetic sequencing seen in the 1990s as scientists aimed to sequence the whole human genome. Advances in sequencing and analytical technologies allowed for increased efficiency and precision, and an integrated, comprehensive approach to understanding organisms followed.
This approach is termed “’omics” and includes the following fields; genomics, transcriptomics, proteomics, fluxomics, and metabolomics. These fields collectively consider all of their respective constituents.
For example, proteomics is the large-scale study of the entire complement of proteins in cell types or organisms. Unlike it’s predecessors, genomics and transcriptomics, proteomics is more complicated as it involves the consideration of post translational modifications, such as phosphorylation. Proteomics has practical applications in protein networks where the study of ways proteins interact aids the field of systems biology, the computational and mathematical analysis and modeling of complex biological systems. Proteomic technologies can be applied to high-throughput techniques, such as mass spectroscopy.
Over the last 30 years, the ’omics have received attention from the research community, the media, and the public alike, largely owing to the advances in scientific understanding that have resulted from ‘omics research. It remains an exciting and fast-paced field of study that is set to continue expanding our knowledge of biological molecules and systems.

Global Market Report: Proteomics

In this article, we discuss the applications of proteomics and its recent developments, along with reviewing the current global market and predicting how the field may evolve in the future.

How is Omics Revolutionizing Cancer Research?

Cytometric Bead Arrays: A Breakdown of the Technique

Compound Identification for Nontargeted Metabolomics

Understanding Native Protein Characterization

Challenges in Environmental Metabolomics

To the Bone: How Proteomics is Uncovering the Mysteries of Ancient DNA

Analyzing Proteomes Using LC-MS/MS

What is Phenomics?

What is Protein Ubiquitylation?

What is Immunoliposome Therapy?

The ‘omics’ Revolution

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Global Market Overview: Metabolomics

Interpreting Proteomics Data

What is Metabolomics?

An Overview of Quantitative Proteomics

Determining Proteins in Milk Using Dumas Analysis

Protein Degradability

Combating Infectious Diseases Through Computational Protein Design

Protein Production: Initiation, Elongation and Termination

What is Western Blotting?

Lipidomics in Food Science

Comparison Between Metabolic Target Analysis and Metabolic Profiling

Omics Approaches to Biomarker Analysis

Using Omics to Harness the Power of Personalized Nutrition

Challenges in Metabolomic Fingerprinting

How are the Metabolome and Proteome Related?

Compound Identification for Nontargeted Metabolomics

A Guide to Optimizing Protein Design

Metabolomics in Toxicology

How have Fluorescent Proteins Transformed Science?

Protein Biosynthesis

Importance of Solubility and Lipophilicity in Drug Development

Applications of Peptidomics

The Human Metabolome Project

What is the Metabolome?

What is Single-Cell Proteomics?

How are Advancements in Mass Spectrometry Impacting Metabolomics Research?

What are G-Protein-Coupled Receptors?

Role of Applied Omics in Precision Medicine

How does the Proteome Differ Between Individuals?

Combining Proteomics and Genomics to Eliminate Disease

What is 'Bottom-Up' Proteomics?

The Role of Metabolomics in Precision Medicine

What are Prions?

Exploring Biosynthetic Diversity

Challenges with Standardization in Lipidomics

What is Phosphoproteomics?

What is 4D Proteomics?

Investigating the Evolution of Microbiome Science

Pharmacokinetics of Cannabis and its Secondary Metabolites

What is Clinical Proteomics?

How do we Radiolabel Proteins?

Insight into the Human Proteoform Project

Discovering Misfolded Proteins using Fluorescent Probes

Effects of Filtered Coffee on Plasma Metabolites

Ethics in Clinical Proteomics

What Role do Proteins Play in Disease?

Applications of Bone Proteomics

Liver Disease Biomarkers

The Steps of Protein Synthesis

Importance of Blood Serum Calorimetry in Lung Cancer Treatment

Environmental Metabolomics

Eliminating American Foulbrood using Endolysins

What is Pharmacometabolomics?

Understanding Neurobiology through Proteins

Importance of Lipidomics in Stem Cell Research

What is Shotgun Lipidomics?

Racial Differences in Protein Biomarkers

An Overview of Protein Localization

Quantifying Protein Diversity: Using DIA-MS to Measure Post-Translational Modifications

A Beginners Guide to Plasma Proteomics

Studying the Metabolic Pathways Between Tissues

Heritability Differences in Metabolic Classes

What is Forensic Proteomics?

Role of Proteomics in COVID-19

How Can Proteins Help Organisms to Tell the Time?

Role of Proteomic Analysis in Skin Regeneration

What is Proteomics?

How to Analyze Macromolecular Protein Complexes

Combating Counterfeit Green Tea with Metabolomic Profiling

Latest Proteomics, Metabolomics and Lipidomics News and Research

Epigenetic Switch Discovery Opens New Target for Cancer Therapy

Cancers emerge from many different paths. One path begins early, in embryonic development, when a protein complex called PRC2, which regulates cell differentiation, identity, and plasticity, becomes dysfunctional.

16 Mar 2026

Solving a 50-year Bottleneck in Chemotherapy Drug Production

A multinational team of researchers has made a significant advance in the manufacturing of doxorubicin, a crucial chemotherapy drug.

16 Mar 2026

Unexpected SRC Localization Offers Promising Target for Cancer Therapies

For five decades, scientists have known about a notorious cancer-causing enzyme called SRC. But they always assumed it only appeared on the inside of cells, where it sent signals that fueled tumor growth and stayed hidden from the immune system.

16 Mar 2026

NuSAP Protein Safeguards Centriole Structure During Cell Division

Biologists at the National University of Singapore (NUS) have uncovered how the protein NuSAP safeguards tiny structures inside cells called centrioles, revealing a mechanism linked to developmental disorders such as microcephaly and mosaic variegated aneuploidy (MVA) syndrome.

13 Mar 2026

New Method Reveals How Tumors Rewire Genetic Splicing Programs

Cancer is caused by faulty genes, but what also shapes a cancer cell's behaviour is how a gene's instructions are trimmed and rearranged before they are turned into the proteins that keep a cell alive.

13 Mar 2026

Comprehensive Brain Atlas Maps Epigenetic Changes During Aging

Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to Parkinson's to ALS and beyond, is expected to double every 20 years.

13 Mar 2026

Dual Mechanism of Deep-Sea Sponge Compound Suppresses Cancer Cell Proliferation

A collaborative research team led by Professor Kaori Sakurai at Tokyo University of Agriculture and Technology, together with Associate Professor Hiroaki Itoh and Professor Masayuki Inoue at Graduate School of Pharmaceutical Sciences, the University of Tokyo, has uncovered a previously unknown mechanism of action of yaku'amide B, a structurally complex peptidic natural product derived from deep-sea sponge found in the waters near Yakushima Island, Japan.

12 Mar 2026

Study Reveals How Altering Cancer’s Protein Machinery Stimulates Antitumor Immunity

A new study led by Pierre Close's team (GIGA, Laboratory of Cancer Signaling, and WELRI Investigator) reveals how subtly disrupting the way tumors produce their proteins can trigger a potent antitumor immune response.

12 Mar 2026

Gut Microbes Reshape Ovarian Aging in Mice

Findings indicate gut microbes impact ovarian function in mice, offering insights into reproductive aging and potential microbiome-based health interventions.

12 Mar 2026

Scientists Map Protein Landscape Driving Photosynthesis in Plant Cells

Research led by scientists at Washington State University has revealed insights on how plants form a microscopic landscape of proteins crucial to photosynthesis, the basis of Earth's food and energy chain.

11 Mar 2026

Computational Tool Improves Detection of Microbes in Tumor Sequencing Data

When scientists sequence tumor DNA, they typically find small amounts of genetic code from bacteria, viruses and fungi – microorganisms that, if actually present in tumor tissues, could influence how they grow, evade immunity or respond to treatment.

11 Mar 2026

How SARS-CoV-2 Hijacks Host tRNA Chemistry to Sustain Infection

Findings reveal coronaviruses exploit stress-linked tRNA modifications, enhancing translation efficiency and offering insights for antiviral drug development.

11 Mar 2026

Whole-Cell Simulation Recreates Molecular Dynamics of Minimal Living Cell

By simulating the life cycle of a minimal bacterial cell - from DNA replication to protein translation to metabolism and cell division - scientists have opened a new frontier of computer vision into the essential processes of life.

10 Mar 2026

Setd8 Enzyme Preserves Retinal Progenitor Identity During Eye Development

The retina is a thin layer of neural tissue at the back of the eye that detects light and converts it into signals, sent to the brain.

10 Mar 2026

Optovolution Uses Light to Guide the Evolution of Dynamic Proteins

Evolution is biology's powerful method of engineering. It works by generating many variants of DNA, RNA, and proteins inside cells and letting nature "select" the organism that performs best.

9 Mar 2026

Discovery of Nuclear Metabolic Fingerprints Offers New Insights Into Cancer

More than two hundred metabolic enzymes, many of which are normally tasked with producing energy in the mitochondria, are also found sitting directly on top of human DNA, according to a study published today in Nature Communications.

9 Mar 2026

A New Framework for High-Efficiency Drug Development

A research team under the direction of the Medical University of Vienna has identified a potential new method for drug development in a recently published review.

9 Mar 2026

How Chromosomal Inversions Lock Beneficial Genes Together for Better Adaptation

When a species lives in two distinct types of habitats, individuals with traits better suited to each habitat will thrive and reproduce, naturally selecting descendants with those traits.

6 Mar 2026

Specialized Tanycyte Brain Cells Found to Play Key Role in Tau Clearance

Accumulation of the protein tau in the brain is one of the hallmarks of Alzheimer's disease. In a paper publishing March 5 in the Cell Press journal Cell Press Blue, researchers report a previously unknown mechanism that appears to enable the build-up of tau.

6 Mar 2026

Three CBX2 Molecules Found to Orchestrate Essential Stem Cell Fate Decisions

A new study has uncovered how an exceptionally scarce protein can orchestrate the assembly of large‑scale gene-silencing structures inside cells, and what happens when that process breaks down.

6 Mar 2026