Proteomics, Metabolomics and Lipidomics

The ‘omics revolution ensued from the surge in genetic sequencing seen in the 1990s as scientists aimed to sequence the whole human genome. Advances in sequencing and analytical technologies allowed for increased efficiency and precision, and an integrated, comprehensive approach to understanding organisms followed.
This approach is termed “’omics” and includes the following fields; genomics, transcriptomics, proteomics, fluxomics, and metabolomics. These fields collectively consider all of their respective constituents.
For example, proteomics is the large-scale study of the entire complement of proteins in cell types or organisms. Unlike it’s predecessors, genomics and transcriptomics, proteomics is more complicated as it involves the consideration of post translational modifications, such as phosphorylation. Proteomics has practical applications in protein networks where the study of ways proteins interact aids the field of systems biology, the computational and mathematical analysis and modeling of complex biological systems. Proteomic technologies can be applied to high-throughput techniques, such as mass spectroscopy.
Over the last 30 years, the ’omics have received attention from the research community, the media, and the public alike, largely owing to the advances in scientific understanding that have resulted from ‘omics research. It remains an exciting and fast-paced field of study that is set to continue expanding our knowledge of biological molecules and systems.

Global Market Report: Proteomics

In this article, we discuss the applications of proteomics and its recent developments, along with reviewing the current global market and predicting how the field may evolve in the future.

Discovering Misfolded Proteins using Fluorescent Probes

Applications of Bone Proteomics

Challenges with Standardization in Lipidomics

Role of Proteomic Analysis in Skin Regeneration

Analyzing Proteomes Using LC-MS/MS

Lipidomics in Food Science

Insight into the Human Proteoform Project

Importance of Lipidomics in Stem Cell Research

Role of Applied Omics in Precision Medicine

Importance of Blood Serum Calorimetry in Lung Cancer Treatment

How is Omics Revolutionizing Cancer Research?

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Environmental Metabolomics

Combating Infectious Diseases Through Computational Protein Design

Understanding Native Protein Characterization

What is 4D Proteomics?

Exploring Biosynthetic Diversity

Global Market Overview: Metabolomics

What are G-Protein-Coupled Receptors?

To the Bone: How Proteomics is Uncovering the Mysteries of Ancient DNA

Studying the Metabolic Pathways Between Tissues

Role of Proteomics in COVID-19

What is Phenomics?

Applications of Peptidomics

How have Fluorescent Proteins Transformed Science?

Challenges in Metabolomic Fingerprinting

Understanding Neurobiology through Proteins

The Role of Metabolomics in Precision Medicine

How are Advancements in Mass Spectrometry Impacting Metabolomics Research?

What is Metabolomics?

Compound Identification for Nontargeted Metabolomics

Protein Degradability

An Overview of Protein Localization

A Guide to Optimizing Protein Design

What is Forensic Proteomics?

An Overview of Quantitative Proteomics

Racial Differences in Protein Biomarkers

Cytometric Bead Arrays: A Breakdown of the Technique

Heritability Differences in Metabolic Classes

Investigating the Evolution of Microbiome Science

Challenges in Environmental Metabolomics

What is Proteomics?

How Can Proteins Help Organisms to Tell the Time?

Metabolomics in Toxicology

What is Western Blotting?

Comparison Between Metabolic Target Analysis and Metabolic Profiling

Combining Proteomics and Genomics to Eliminate Disease

A Beginners Guide to Plasma Proteomics

Liver Disease Biomarkers

Protein Production: Initiation, Elongation and Termination

What is Protein Ubiquitylation?

What is Immunoliposome Therapy?

What is Phosphoproteomics?

The Human Metabolome Project

Omics Approaches to Biomarker Analysis

Importance of Solubility and Lipophilicity in Drug Development

Protein Biosynthesis

Pharmacokinetics of Cannabis and its Secondary Metabolites

How does the Proteome Differ Between Individuals?

What is Single-Cell Proteomics?

Quantifying Protein Diversity: Using DIA-MS to Measure Post-Translational Modifications

How do we Radiolabel Proteins?

Effects of Filtered Coffee on Plasma Metabolites

Interpreting Proteomics Data

What is Shotgun Lipidomics?

What is Clinical Proteomics?

The Steps of Protein Synthesis

Eliminating American Foulbrood using Endolysins

What is the Metabolome?

What is Pharmacometabolomics?

Using Omics to Harness the Power of Personalized Nutrition

How are the Metabolome and Proteome Related?

Compound Identification for Nontargeted Metabolomics

What are Prions?

The ‘omics’ Revolution

Combating Counterfeit Green Tea with Metabolomic Profiling

How to Analyze Macromolecular Protein Complexes

Determining Proteins in Milk Using Dumas Analysis

What Role do Proteins Play in Disease?

What is 'Bottom-Up' Proteomics?

Ethics in Clinical Proteomics

Latest Proteomics, Metabolomics and Lipidomics News and Research

USP15 Protein May Help Ovarian Cancer Resist Chemotherapy

Blocking USP15 in ovarian cancer cells disrupts growth and enhances chemotherapy sensitivity, revealing a potential target for overcoming treatment resistance.

1 Oct 2026

Experts Extend Lives of Animals By Activating ‘Energy Saver’ Mode

The study, published today in Aging Cell, found strong evidence that triggering a protein governing energy level may help organisms live longer, in some cases by over 25%.

1 Oct 2026

Single-Molecule Optical Tweezers Visualize Real-Time Dynamic Protein and DNA Interactions

A protein that's essential to every cell's ability to turn off unnecessary genes is well known for its key function of compacting genes and its connection to cancer when it undergoes mutation.

1 Oct 2026

Electron Microscopy Imaging Confirms Piezo1-Dependent Axonal Sheath Structural Remodeling

Researchers at Upstate Medical University have identified a key mechanism that helps determine the length of myelin, the protective coating that surrounds many nerve fibers and allows signals to travel efficiently through the nervous system.

1 Oct 2026

Single-Molecule Optical Tweezers Visualize Real-Time Dynamic Protein and DNA Interactions

A protein that's essential to every cell's ability to turn off unnecessary genes is well known for its key function of compacting genes and its connection to cancer when it undergoes mutation. But until now, scientists weren't quite sure how the protein gets where it needs to go to keep genes bound up so they aren't activated.

1 Oct 2026

Single-Cell Metabolic Profiling Identifies Key Bioenergetic Targets in Human Tumor Tissue

Immune cells can reach head and neck tumors, but once there, many stop functioning. This helps explain why immunotherapy with immune checkpoint inhibitors - which have transformed treatment for some cancers - benefit only 17%–23% of patients with head and neck squamous cell carcinoma. These are cancers that arise from cells lining the mouth, throat and voicebox.

1 Oct 2026

Kupffer Cells Increase Apolipoprotein Secretion in Response to Indigestible Plastics

Microplastics appear capable of significantly impairing the function of phagocytes in the liver, at least in mice. In turn, this disrupts the metabolism of this vital organ and increases the build-up of fat inside it. These are the key findings from a joint German-Austrian study led by the University of Bonn, details of which have now been published in the journal "Nature Metabolism."

1 Oct 2026

A Flash of Blue Light Helped Cells Overcome a Major Division Defect

Cell division represents a complex process. Central to this intricacy is a cellular structure devoid of a membrane, known as the centrosome, consisting of over 200 different components.

30 Sep 2026

Innovative OpenFISH Technique Enables Integrated Spatial Molecular Imaging in Tissues

Spatial transcriptomics (ST) shows which genes are being expressed and where within a tissue. Spatial metabolomics (SM), on the other hand, maps the location of metabolites—small molecules produced or used by cells—within tissue.

30 Sep 2026

Gut-Derived Neutral Ceramidase Regulates MASH Through Microbial and Epithelial Signaling

Metabolic dysfunction-associated steatohepatitis (MASH) is often viewed through the lens of hepatic lipid accumulation, inflammation and fibrosis.

30 Sep 2026

Targeted Y Chromosome Deletions Disrupt Key Cellular Immune Response Pathways

A new study found that cancer cells selectively chip away gene-rich sections of the Y chromosome, triggering ripples that regulate tumor growth.

29 Sep 2026

Study Establishes Immune Cell Trafficking as Viable Alzheimer's Target

There is no treatment available today to stop the death of brain cells in neurodegenerative diseases known as tauopathies, including Alzheimer's disease, in which twisted clumps of a protein called tau accumulate in the brain.

29 Sep 2026

Single-Cell Sequencing Confirms Epigenetic Remodeling Across Diverse Cardiac Cell Types

The adult human heart is a reliable and resilient engine fueling our everyday lives while also being responsive enough to supercharge a Usain Bolt sprint or sustain a three-week bike race in the French Alps and Pyrenees.

29 Sep 2026

Scientists Pinpoint the Brain Circuit That Regulates Metabolism

As the body’s temperature decreases, it compensates by utilizing additional energy to produce heat and stimulating the desire to eat to replenish the energy expended for warmth.

28 Sep 2026

Post-Translational Modification Crosstalk Regulates Oncogenic Protein Stability and Activity

A review published in Genes & Diseases highlights the complex interplay between protein arginine methylation and ubiquitination, two forms of protein modification that can profoundly influence cancer development, progression and treatment response. The article brings together current understanding of how these interconnected molecular processes regulate proteins involved in cancer and identifies opportunities for future therapeutic approaches.

28 Sep 2026