Proteomics, Metabolomics and Lipidomics

The ‘omics revolution ensued from the surge in genetic sequencing seen in the 1990s as scientists aimed to sequence the whole human genome. Advances in sequencing and analytical technologies allowed for increased efficiency and precision, and an integrated, comprehensive approach to understanding organisms followed.
This approach is termed “’omics” and includes the following fields; genomics, transcriptomics, proteomics, fluxomics, and metabolomics. These fields collectively consider all of their respective constituents.
For example, proteomics is the large-scale study of the entire complement of proteins in cell types or organisms. Unlike it’s predecessors, genomics and transcriptomics, proteomics is more complicated as it involves the consideration of post translational modifications, such as phosphorylation. Proteomics has practical applications in protein networks where the study of ways proteins interact aids the field of systems biology, the computational and mathematical analysis and modeling of complex biological systems. Proteomic technologies can be applied to high-throughput techniques, such as mass spectroscopy.
Over the last 30 years, the ’omics have received attention from the research community, the media, and the public alike, largely owing to the advances in scientific understanding that have resulted from ‘omics research. It remains an exciting and fast-paced field of study that is set to continue expanding our knowledge of biological molecules and systems.

Global Market Report: Proteomics

In this article, we discuss the applications of proteomics and its recent developments, along with reviewing the current global market and predicting how the field may evolve in the future.

How do we Radiolabel Proteins?

Environmental Metabolomics

Compound Identification for Nontargeted Metabolomics

What is Shotgun Lipidomics?

Role of Applied Omics in Precision Medicine

How does the Proteome Differ Between Individuals?

Cytometric Bead Arrays: A Breakdown of the Technique

Ethics in Clinical Proteomics

Using Omics to Harness the Power of Personalized Nutrition

Importance of Solubility and Lipophilicity in Drug Development

Global Market Overview: Metabolomics

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Discovering Misfolded Proteins using Fluorescent Probes

Racial Differences in Protein Biomarkers

What are G-Protein-Coupled Receptors?

What is Protein Ubiquitylation?

What is 4D Proteomics?

The ‘omics’ Revolution

An Overview of Protein Localization

What is 'Bottom-Up' Proteomics?

Importance of Blood Serum Calorimetry in Lung Cancer Treatment

Heritability Differences in Metabolic Classes

What is Immunoliposome Therapy?

Lipidomics in Food Science

A Beginners Guide to Plasma Proteomics

How to Analyze Macromolecular Protein Complexes

Interpreting Proteomics Data

A Guide to Optimizing Protein Design

Quantifying Protein Diversity: Using DIA-MS to Measure Post-Translational Modifications

Analyzing Proteomes Using LC-MS/MS

Understanding Neurobiology through Proteins

What is Phosphoproteomics?

Importance of Lipidomics in Stem Cell Research

Protein Production: Initiation, Elongation and Termination

How are the Metabolome and Proteome Related?

Understanding Native Protein Characterization

Challenges in Metabolomic Fingerprinting

The Steps of Protein Synthesis

Studying the Metabolic Pathways Between Tissues

Applications of Bone Proteomics

Role of Proteomics in COVID-19

What is Western Blotting?

Combating Counterfeit Green Tea with Metabolomic Profiling

What are Prions?

Protein Biosynthesis

Combating Infectious Diseases Through Computational Protein Design

Protein Degradability

Combining Proteomics and Genomics to Eliminate Disease

The Role of Metabolomics in Precision Medicine

How have Fluorescent Proteins Transformed Science?

What is Phenomics?

What is Pharmacometabolomics?

How are Advancements in Mass Spectrometry Impacting Metabolomics Research?

To the Bone: How Proteomics is Uncovering the Mysteries of Ancient DNA

Metabolomics in Toxicology

What Role do Proteins Play in Disease?

What is Metabolomics?

Comparison Between Metabolic Target Analysis and Metabolic Profiling

How is Omics Revolutionizing Cancer Research?

An Overview of Quantitative Proteomics

Liver Disease Biomarkers

What is the Metabolome?

What is Proteomics?

What is Clinical Proteomics?

Investigating the Evolution of Microbiome Science

Eliminating American Foulbrood using Endolysins

Role of Proteomic Analysis in Skin Regeneration

Compound Identification for Nontargeted Metabolomics

Challenges in Environmental Metabolomics

Challenges with Standardization in Lipidomics

Applications of Peptidomics

The Human Metabolome Project

Pharmacokinetics of Cannabis and its Secondary Metabolites

Exploring Biosynthetic Diversity

Effects of Filtered Coffee on Plasma Metabolites

What is Forensic Proteomics?

Insight into the Human Proteoform Project

Omics Approaches to Biomarker Analysis

How Can Proteins Help Organisms to Tell the Time?

What is Single-Cell Proteomics?

Determining Proteins in Milk Using Dumas Analysis

Latest Proteomics, Metabolomics and Lipidomics News and Research

Study Reveals Mitochondria Plug Straight Into the Nuclear Command

For generations, textbooks have taught that a cell's energy simply drifts to wherever it is needed.

11 Jun 2026

New Cell Therapy Modifies Natural Killer Cells Against Cancer

Scientists have made great progress in harnessing the body's own immune cells to treat so-called liquid tumors, cancers of the blood and lymphatic system.

11 Jun 2026

Tail Region of mRNAs Found to Act as Protein Chaperone

Proteins are how cells get work done. They carry out nearly every important cellular task, from ferrying messages to controlling which genes are turned on or off.

10 Jun 2026

DNA Barcode Technology Enables Massive Simultaneous Drug Candidate Validation

A Korean research team has launched a public drug discovery service capable of screening and validating tens of millions of compounds simultaneously.

10 Jun 2026

Auxin-Induced Transcriptional Complex Regulates Garlic Somatic Embryogenesis

Garlic (Allium sativum L.) is usually propagated through bulbs rather than seeds, a pattern that can lead to variety degeneration, low multiplication rates, and the accumulation of viral diseases.

10 Jun 2026

Researchers Outline Dynamic Protein Control Systems for Better Clinical Decisions

Cancer has often been explained through mutations in deoxyribonucleic acid (DNA) or changes in ribonucleic acid (RNA), but these layers do not fully explain why tumors with similar genetic profiles can behave differently.

10 Jun 2026

Mylpf Protein Identified as a Linchpin for Healthy Muscle Formation

University of Maine researchers have published new findings about how muscles form, why certain muscle diseases develop and why symptoms may not appear until years after muscle degeneration begins.

9 Jun 2026

Coffee Can Now Serve as a Biological Switch for Medicines

For many of us, a warm cup of coffee is how we start our day. For Texas A&M Health researchers, it may also offer a new way to control engineered cells in future medicines.

9 Jun 2026

Salk Researchers Uncover Specialized Plant Protein for DNA Repair

Similar to the way DNA damage can contribute to human diseases like cancer, it can also disrupt growth, development, and survival in plants.

9 Jun 2026

New Open Access Connectome Unveils Intricate Fruit Fly Neural Connections

In a first, a large, international team led by multiple labs at Harvard Medical School and Princeton University has published a complete wiring diagram of all the connections between neurons in the central nervous system of an adult fruit fly.

9 Jun 2026

Scientists Identify EHMT2 Enzyme as Main Cause of 5-FU Failure

One of the most widely used chemotherapeutic agents for colorectal cancer is 5-fluorouracil (5-FU), a cornerstone treatment that has improved outcomes for countless patients.

9 Jun 2026

Creatine Linked to Cancer-Fighting Dendritic Cell Function

According to recent UCLA research, creatine, the organic acid that athletes and bodybuilders frequently use as a supplement, supercharges a crucial class of immune cells that activate and prime the body's primary cancer-fighting agents.

8 Jun 2026

Label-Free Raman Spectroscopy Accelerates Precision Phage Therapy

This study was led by Prof. Jian Xu (Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences) in collaboration with Prof. Hongzhou Lu (Shenzhen Third People's Hospital) and Prof. Jiadong Huang (University of Jinan).

8 Jun 2026

New Method Dissects Light Signaling and Heme Pathways in Chloroplast Formation

For plants, light is an important environmental factor not only as a source of energy for photosynthesis but also as a signal for capturing environmental information. Light signals are sensed by photoreceptor proteins called phytochrome. The amino acids that make up proteins are transparent and cannot absorb visible light.

8 Jun 2026

Study Shows Environmental Mixing Drives Primitive RNA to Extinction

Recent research showed that an artificially constructed RNA self-replicating system modeling primitive life at the origin of life evolved to become more prone to extinction under certain experimental conditions.

8 Jun 2026

Antibody-Directed Xenophagy Pathway Blocks Intracellular Infections From Spreading

Scientists have revealed the process by which cells can internally digest bacteria and viruses.

5 Jun 2026

Microbes Reveal Missing Link in Space Manufacturing

Manufacturing materials in space may hinge on a simple problem: feeding microbes.

5 Jun 2026

Blood Signature Found to Predict Lung Cancer Risk Years Before Diagnosis

Researchers have identified a blood signature that can predict lung cancer risk years before diagnosis – significant findings that could enhance prevention strategies for Australia’s biggest cancer killer.

5 Jun 2026

Researchers Reconstruct the Billion Year History of Osmotrophic Eukaryotic Evolution

Decomposers are crucial for keeping Earth habitable, breaking down dead biomass and returning key nutrients, like carbon, nitrogen and phosphorus, back into the ecosystem.

5 Jun 2026

New Antibiotic Compound Blocks Ribosome to Starve Dangerous Pathogens

Researchers at McMaster University have discovered a new antibiotic that kills some of the world's most dangerous and drug-resistant bacteria - and does so by targeting a previously unknown vulnerability, opening the door to an entirely new class of treatments.

5 Jun 2026