Proteomics, Metabolomics and Lipidomics

The ‘omics revolution ensued from the surge in genetic sequencing seen in the 1990s as scientists aimed to sequence the whole human genome. Advances in sequencing and analytical technologies allowed for increased efficiency and precision, and an integrated, comprehensive approach to understanding organisms followed.
This approach is termed “’omics” and includes the following fields; genomics, transcriptomics, proteomics, fluxomics, and metabolomics. These fields collectively consider all of their respective constituents.
For example, proteomics is the large-scale study of the entire complement of proteins in cell types or organisms. Unlike it’s predecessors, genomics and transcriptomics, proteomics is more complicated as it involves the consideration of post translational modifications, such as phosphorylation. Proteomics has practical applications in protein networks where the study of ways proteins interact aids the field of systems biology, the computational and mathematical analysis and modeling of complex biological systems. Proteomic technologies can be applied to high-throughput techniques, such as mass spectroscopy.
Over the last 30 years, the ’omics have received attention from the research community, the media, and the public alike, largely owing to the advances in scientific understanding that have resulted from ‘omics research. It remains an exciting and fast-paced field of study that is set to continue expanding our knowledge of biological molecules and systems.

Global Market Report: Proteomics

In this article, we discuss the applications of proteomics and its recent developments, along with reviewing the current global market and predicting how the field may evolve in the future.

Environmental Metabolomics

What is Protein Ubiquitylation?

Understanding Native Protein Characterization

The ‘omics’ Revolution

Liver Disease Biomarkers

Combating Infectious Diseases Through Computational Protein Design

What is 'Bottom-Up' Proteomics?

Applications of Bone Proteomics

Compound Identification for Nontargeted Metabolomics

Role of Proteomics in COVID-19

The Steps of Protein Synthesis

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Role of Applied Omics in Precision Medicine

Ethics in Clinical Proteomics

How does the Proteome Differ Between Individuals?

An Overview of Quantitative Proteomics

What is the Metabolome?

Racial Differences in Protein Biomarkers

Omics Approaches to Biomarker Analysis

What is Proteomics?

What is Single-Cell Proteomics?

What is Clinical Proteomics?

What is Forensic Proteomics?

Combining Proteomics and Genomics to Eliminate Disease

An Overview of Protein Localization

How Can Proteins Help Organisms to Tell the Time?

Applications of Peptidomics

A Guide to Optimizing Protein Design

Heritability Differences in Metabolic Classes

The Human Metabolome Project

What is Immunoliposome Therapy?

Metabolomics in Toxicology

Comparison Between Metabolic Target Analysis and Metabolic Profiling

Determining Proteins in Milk Using Dumas Analysis

Studying the Metabolic Pathways Between Tissues

What are Prions?

Eliminating American Foulbrood using Endolysins

Analyzing Proteomes Using LC-MS/MS

Understanding Neurobiology through Proteins

What is Phosphoproteomics?

Combating Counterfeit Green Tea with Metabolomic Profiling

Challenges in Metabolomic Fingerprinting

Insight into the Human Proteoform Project

Quantifying Protein Diversity: Using DIA-MS to Measure Post-Translational Modifications

Role of Proteomic Analysis in Skin Regeneration

Interpreting Proteomics Data

Protein Production: Initiation, Elongation and Termination

Global Market Overview: Metabolomics

To the Bone: How Proteomics is Uncovering the Mysteries of Ancient DNA

Using Omics to Harness the Power of Personalized Nutrition

Challenges in Environmental Metabolomics

Exploring Biosynthetic Diversity

Effects of Filtered Coffee on Plasma Metabolites

Compound Identification for Nontargeted Metabolomics

Pharmacokinetics of Cannabis and its Secondary Metabolites

How is Omics Revolutionizing Cancer Research?

What is 4D Proteomics?

How are the Metabolome and Proteome Related?

Discovering Misfolded Proteins using Fluorescent Probes

Investigating the Evolution of Microbiome Science

Cytometric Bead Arrays: A Breakdown of the Technique

Protein Biosynthesis

What is Shotgun Lipidomics?

What is Western Blotting?

What is Metabolomics?

What is Pharmacometabolomics?

How do we Radiolabel Proteins?

Importance of Lipidomics in Stem Cell Research

Lipidomics in Food Science

Challenges with Standardization in Lipidomics

Protein Degradability

How to Analyze Macromolecular Protein Complexes

What is Phenomics?

The Role of Metabolomics in Precision Medicine

What are G-Protein-Coupled Receptors?

Importance of Blood Serum Calorimetry in Lung Cancer Treatment

How are Advancements in Mass Spectrometry Impacting Metabolomics Research?

A Beginners Guide to Plasma Proteomics

Importance of Solubility and Lipophilicity in Drug Development

How have Fluorescent Proteins Transformed Science?

What Role do Proteins Play in Disease?

Latest Proteomics, Metabolomics and Lipidomics News and Research

Why the Brain Never Stops Trying to Replace Myelin-Producing Cells

Researchers from Johns Hopkins Medicine, utilizing mouse models, reveal that oligodendrocyte precursor cells differentiate at a consistent, extensive rate throughout adulthood.

23 Jan 2026

Cytomegalovirus can Hijack a Central 'Traffic Controller' for Immune Cells

In a major scientific breakthrough, researchers from Monash University and the Lions Eye Institute have discovered a tissue protein that acts as a central 'traffic controller' for immune cells and can be hijacked by a virus to weaken immune responses.

22 Jan 2026

Coordinated Gene Regulation Drives Saponin Production

Triterpenoid saponins are widely valued for their diverse pharmacological activities and also play important defensive roles in plants.

22 Jan 2026

DHPS Enzyme Deficiency Impairs Macrophage Development and Tissue Repair

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health found that an enzyme involved in protein translation is essential for circulating immune cells, called monocytes, to mature into tissue-resident macrophages, a specialized population of immune cells that maintain organ health by clearing dead cells and debris.

22 Jan 2026

Freeze Thaw Cycles Reveal How Lipid Membranes Shape Early Protocell Evolution

Modern cells are complex chemical entities with cytoskeletons, finely regulated internal and external molecules, and genetic material that determines nearly every aspect of their functioning.

21 Jan 2026

Hidden Sperm RNA Remodeling With Age May Impact Next Generation

Increasing paternal age has been linked to elevated health risks for the next generation, including higher risks of obesity and stillbirth. But what drives this increased risk remains unknown.

21 Jan 2026

Yeast-Based Platform Achieves Animal-Free High Quality Chondroitin Sulfate

By systematically redesigning multiple metabolic modules inside Komagataella phaffii, the researchers achieved both high product yield and high sulfation quality, two goals that have long been difficult to reach at the same time.

21 Jan 2026

Engineering Escherichia coli for Sustainable Biosynthesis of Lauryl Glucoside

By reconstructing a non-natural metabolic route in Escherichia coli, the researchers demonstrated that simple sugars can be biologically converted into lauryl glucoside through the coordinated production of its fatty alcohol precursor and a final glycosylation step.

21 Jan 2026

Rigid Protein Molecular Rulers Enable Precise Control of Antibody Conformation

By extending a naturally rigid bacterial protein by 50% while preserving geometry and stability, the study introduces protein-based "molecular rulers" that could probe antibody shape, limit unwanted motion, and support safer, more effective antibody drug design.

21 Jan 2026

How Far-Red Light Stops Biofilms in Drug-Resistant Bacteria

Light is a fundamental signal affecting every form of life. Cycles of light and dark help set the biological clocks in organisms from unicellular bacteria to humans.

21 Jan 2026

Engineered Human Skin Acts as a Living Biosensor for Inflammation

Implanted living skin-based biosensors offer a breakthrough in inflammation tracking, providing real-time biomarker monitoring without invasive procedures.

21 Jan 2026

Dr Adam Davenport Appointed as CSO to Strengthen Leadership in Integrated Drug Discovery

We are pleased to announce the appointment of Dr Adam Davenport as Chief Scientific Officer to spearhead our integrated drug discovery offering for biotech and pharmaceutical partners.

From Concept Life Sciences 19 Jan 2026

Decoding the Molecular Logic of Histamine Signaling in the Brain

Many people are familiar with histamine, a biological molecule, that serves as a key driver of allergic reactions and other immune responses.

19 Jan 2026

A Hidden Nanomachine Behind Constant Cellular Secretion

Scientists uncover the tiny machine that delivers essential molecular packages to the cell surface, a fundamental activity for maintaining healthy cells.

19 Jan 2026

Mapping the Human E3 Ligase Landscape

Maintaining cellular order is a major logistical challenge: Individual mammalian cells contain billions of protein molecules, which must be synthesized, deployed, and removed with precision.

19 Jan 2026

Model Proteins Could Bring Order to Protein Science

Protein scientists could improve reproducibility and coordination across the field by rallying around a small, shared set of "model proteins," according to a new Perspective by Connecticut College chemist Marc Zimmer.

19 Jan 2026

Replacing Large Mouse Gene Regions with Human DNA

Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes with entire human sequences has posed significant technical challenges.

19 Jan 2026

Study Overturns Understanding About How T Cells Recognize Lipid Antigens

A new discovery about how cells communicate with each other in the body's immune system has revealed deeper insights for an international team of scientists into fundamental immune system function.

16 Jan 2026

Unveiling How a Respiratory Bacterium Obtains Lipids and Targets Fatty Tissues

A multidisciplinary team has uncovered a key mechanism that allows the human bacterium Mycoplasma pneumoniae-responsible for atypical pneumonia and other respiratory infections-to obtain cholesterol and other essential lipids directly from the human body.

16 Jan 2026