Proteomics, Metabolomics and Lipidomics

The ‘omics revolution ensued from the surge in genetic sequencing seen in the 1990s as scientists aimed to sequence the whole human genome. Advances in sequencing and analytical technologies allowed for increased efficiency and precision, and an integrated, comprehensive approach to understanding organisms followed.
This approach is termed “’omics” and includes the following fields; genomics, transcriptomics, proteomics, fluxomics, and metabolomics. These fields collectively consider all of their respective constituents.
For example, proteomics is the large-scale study of the entire complement of proteins in cell types or organisms. Unlike it’s predecessors, genomics and transcriptomics, proteomics is more complicated as it involves the consideration of post translational modifications, such as phosphorylation. Proteomics has practical applications in protein networks where the study of ways proteins interact aids the field of systems biology, the computational and mathematical analysis and modeling of complex biological systems. Proteomic technologies can be applied to high-throughput techniques, such as mass spectroscopy.
Over the last 30 years, the ’omics have received attention from the research community, the media, and the public alike, largely owing to the advances in scientific understanding that have resulted from ‘omics research. It remains an exciting and fast-paced field of study that is set to continue expanding our knowledge of biological molecules and systems.

Global Market Report: Proteomics

In this article, we discuss the applications of proteomics and its recent developments, along with reviewing the current global market and predicting how the field may evolve in the future.

Global Market Overview: Metabolomics

What is Proteomics?

What is Single-Cell Proteomics?

Racial Differences in Protein Biomarkers

Combining Proteomics and Genomics to Eliminate Disease

Using Omics to Harness the Power of Personalized Nutrition

How is Omics Revolutionizing Cancer Research?

Insight into the Human Proteoform Project

Omics Approaches to Biomarker Analysis

The Role of Metabolomics in Precision Medicine

The Human Metabolome Project

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Role of Applied Omics in Precision Medicine

What is Metabolomics?

Challenges with Standardization in Lipidomics

To the Bone: How Proteomics is Uncovering the Mysteries of Ancient DNA

Ethics in Clinical Proteomics

Applications of Peptidomics

How do we Radiolabel Proteins?

What is Clinical Proteomics?

Understanding Native Protein Characterization

What is 'Bottom-Up' Proteomics?

What is Shotgun Lipidomics?

A Beginners Guide to Plasma Proteomics

Lipidomics in Food Science

Protein Biosynthesis

What are Prions?

Challenges in Environmental Metabolomics

Discovering Misfolded Proteins using Fluorescent Probes

Compound Identification for Nontargeted Metabolomics

Combating Infectious Diseases Through Computational Protein Design

What is Forensic Proteomics?

Eliminating American Foulbrood using Endolysins

Environmental Metabolomics

How are the Metabolome and Proteome Related?

Importance of Lipidomics in Stem Cell Research

Interpreting Proteomics Data

What Role do Proteins Play in Disease?

Metabolomics in Toxicology

What is 4D Proteomics?

What is Phosphoproteomics?

Importance of Blood Serum Calorimetry in Lung Cancer Treatment

What is Protein Ubiquitylation?

What is the Metabolome?

Applications of Bone Proteomics

What are G-Protein-Coupled Receptors?

A Guide to Optimizing Protein Design

Determining Proteins in Milk Using Dumas Analysis

Role of Proteomic Analysis in Skin Regeneration

An Overview of Protein Localization

Liver Disease Biomarkers

What is Pharmacometabolomics?

Protein Degradability

Comparison Between Metabolic Target Analysis and Metabolic Profiling

Analyzing Proteomes Using LC-MS/MS

Challenges in Metabolomic Fingerprinting

The Steps of Protein Synthesis

Effects of Filtered Coffee on Plasma Metabolites

How have Fluorescent Proteins Transformed Science?

Compound Identification for Nontargeted Metabolomics

Combating Counterfeit Green Tea with Metabolomic Profiling

Protein Production: Initiation, Elongation and Termination

What is Phenomics?

Importance of Solubility and Lipophilicity in Drug Development

How does the Proteome Differ Between Individuals?

What is Immunoliposome Therapy?

Heritability Differences in Metabolic Classes

Exploring Biosynthetic Diversity

Pharmacokinetics of Cannabis and its Secondary Metabolites

Understanding Neurobiology through Proteins

The ‘omics’ Revolution

How Can Proteins Help Organisms to Tell the Time?

Role of Proteomics in COVID-19

An Overview of Quantitative Proteomics

What is Western Blotting?

How are Advancements in Mass Spectrometry Impacting Metabolomics Research?

Studying the Metabolic Pathways Between Tissues

Quantifying Protein Diversity: Using DIA-MS to Measure Post-Translational Modifications

Investigating the Evolution of Microbiome Science

How to Analyze Macromolecular Protein Complexes

Cytometric Bead Arrays: A Breakdown of the Technique

Latest Proteomics, Metabolomics and Lipidomics News and Research

Antisense Therapy Shows Promise Against Parkinson's

Parkinson's disease (PD), as well as many other neurodegenerative disorders, has shown a link between the abnormal aggregation of a protein called α-synuclein (aSyn) and neuronal death. These aggregates, known as Lewy bodies and Lewy neurites depending on their subcellular localization, can spread by continuously causing normal endogenous aSyn to misfold.

26 Jul 2024

DNA Sequence Variants Drive Link Between Methylation and Gene Expression

The relationship between DNA methylation and gene expression is driven by sequence variants, according to a recent study conducted by researchers at deCODE Genetics, an Amgen subsidiary.

25 Jul 2024

Probing Plasma Membrane Dynamics with Cryo-Electron Microscopy

Cell membranes play a crucial role in maintaining the integrity and functionality of cells. However, the mechanisms by which they perform these roles are not yet fully understood.

25 Jul 2024

Study Reveals Titin Mutation Effects on Cardiac Development and Atrial Fibrillation

Millions of adults have atrial fibrillation -; an irregular beating of the upper chambers of the heart that yields increased risk of heart failure, stroke and death.

25 Jul 2024

New Assay Fast-Tracks Virucidal Testing

An innovative technique that can quickly ascertain whether a virus is contagious or not has the potential to completely transform how humans respond to pandemics in the future.

24 Jul 2024

Understanding Gibberellin's Dual Role in Legume Nodule Development

Researchers at the University of Cambridge demonstrate that the plant hormone gibberellin (GA) is essential for the formation and maturation of nitrogen-fixing root nodules in legumes and can also increase nodule size.

24 Jul 2024

New Tool GeneMAP Unveils Key Insights into Cell Metabolism

There's a glaring gap in our knowledge of cell metabolism: in many cases, we still don't know exactly how nutrients are transported into the cell.

24 Jul 2024

Study Shows the Impact of Exposome on Serum Metabolites in Children

The combined effect of environmental exposures and unhealthy lifestyle habits can affect children's cardiometabolic health in a way that exceeds their separate effects.

24 Jul 2024

Novel ATP Imaging System Reveals Insights into Kidney Energy Metabolism

The prevalence of kidney disease has been increasing in Japan, with it now affecting one in eight adults, but developing effective treatment remains a challenge.

24 Jul 2024

Decoding Dengue: The Use of Less Efficient Codons for Viral Advantage

Mosquito-borne viral infections once confined to tropical regions are spreading. Dengue virus infects up to 400 million people worldwide each year according to World Health Organization estimates, and no available treatments exist for this disease.

24 Jul 2024

Study Shows the Ability of Protein 'Signatures' to Predict Onset of 67 Diseases

Research on thousands of proteins measured from a drop of blood demonstrates the ability of proteins to predict the onset of many diverse diseases.

24 Jul 2024

RNA Technology Enables Precise Control of Gene Networks

Scientists have created a smart RNA that can control networks in response to different signals by converting guide RNAs, which normally direct enzymes. The scholarly community is paying close attention to this ground-breaking study.

23 Jul 2024

Machine Learning and Infrared Light Unlock Health Insights

Researchers at Ludwig-Maximilians-Universität München (LMU) and the Max Planck Institute of Quantum Optics (MPQ), in collaboration with Helmholtz Zentrum München, are pioneering a new approach to health screening.

22 Jul 2024

Researchers Capture Protein Tangle Formation in Real-Time

Protein tangles known as amyloid-beta (A-beta) aggregates are most famously linked to neurodegenerative illnesses like Alzheimer's. Nevertheless, despite its frequent attention, scientists have not been able to fully comprehend how A-beta assembles and disassembles.

22 Jul 2024

UNC Charlotte Study: SARS-CoV-2 Variants BA.2.86 and JN.1 Show Minimal Immune Evasion

New research from UNC Charlotte's Center for Computational Intelligence to Predict Health and Environmental Risks (CIPHER) has found that the two recent and prevalent strains of the virus that cause COVID-19, SARS-CoV-2 variants BA.2.86 and JN.1, are not significantly better than their predecessor Omicron at evading immune responses and causing infections despite having a high number of mutations compared to Omicron.

22 Jul 2024

Rhythmic Gene Expression Regulates Root Nodule Formation in Legumes

Legumes thrive in low-nitrogen environments by partnering with rhizobia, soil bacteria that convert atmospheric nitrogen into ammonium, a usable form for the plants.

22 Jul 2024

Rice Scientists Unveil the Mechanisms Behind Viral Release Timing

New research from Rice University scientists is shedding light on how viruses ensure their survival by precisely timing the release of new viruses.

22 Jul 2024

Ginseng Genome Map Unlocks New Possibilities for Medicinal Applications

A landmark study has successfully decoded the complete ginseng genome, unveiling the genetic mechanisms that govern saponin biosynthesis. This detailed genetic map illuminates the evolutionary and metabolic pathways of Panax ginseng, a staple in traditional medicine.

19 Jul 2024

Flu Virus Exploits Immune System Weakness to Infect Cells

The majority of influenza viruses enter animal or human cells through particular surface-based pathways. It has recently been found by researchers at the University of Zurich that some influenza viruses, both human and avian, can also enter cells through a second entry point that involves an immune system protein complex.

18 Jul 2024