Proteomics, Metabolomics and Lipidomics

The ‘omics revolution ensued from the surge in genetic sequencing seen in the 1990s as scientists aimed to sequence the whole human genome. Advances in sequencing and analytical technologies allowed for increased efficiency and precision, and an integrated, comprehensive approach to understanding organisms followed.
This approach is termed “’omics” and includes the following fields; genomics, transcriptomics, proteomics, fluxomics, and metabolomics. These fields collectively consider all of their respective constituents.
For example, proteomics is the large-scale study of the entire complement of proteins in cell types or organisms. Unlike it’s predecessors, genomics and transcriptomics, proteomics is more complicated as it involves the consideration of post translational modifications, such as phosphorylation. Proteomics has practical applications in protein networks where the study of ways proteins interact aids the field of systems biology, the computational and mathematical analysis and modeling of complex biological systems. Proteomic technologies can be applied to high-throughput techniques, such as mass spectroscopy.
Over the last 30 years, the ’omics have received attention from the research community, the media, and the public alike, largely owing to the advances in scientific understanding that have resulted from ‘omics research. It remains an exciting and fast-paced field of study that is set to continue expanding our knowledge of biological molecules and systems.

Global Market Report: Proteomics

In this article, we discuss the applications of proteomics and its recent developments, along with reviewing the current global market and predicting how the field may evolve in the future.

Metabolomics in Toxicology

Discovering Misfolded Proteins using Fluorescent Probes

Role of Applied Omics in Precision Medicine

To the Bone: How Proteomics is Uncovering the Mysteries of Ancient DNA

What is Shotgun Lipidomics?

Challenges with Standardization in Lipidomics

Analyzing Proteomes Using LC-MS/MS

What is Protein Ubiquitylation?

Challenges in Metabolomic Fingerprinting

An Overview of Protein Localization

Protein Biosynthesis

See more featured articles »

Exploring Biosynthetic Diversity

The ‘omics’ Revolution

An Overview of Quantitative Proteomics

What is Phosphoproteomics?

What are G-Protein-Coupled Receptors?

How does the Proteome Differ Between Individuals?

Comparison Between Metabolic Target Analysis and Metabolic Profiling

What are Prions?

How are Advancements in Mass Spectrometry Impacting Metabolomics Research?

Liver Disease Biomarkers

A Guide to Optimizing Protein Design

What is Pharmacometabolomics?

Combining Proteomics and Genomics to Eliminate Disease

Eliminating American Foulbrood using Endolysins

Importance of Blood Serum Calorimetry in Lung Cancer Treatment

Understanding Neurobiology through Proteins

Applications of Bone Proteomics

What is Phenomics?

What is Western Blotting?

Challenges in Environmental Metabolomics

Heritability Differences in Metabolic Classes

A Beginners Guide to Plasma Proteomics

What is Clinical Proteomics?

Importance of Solubility and Lipophilicity in Drug Development

What is the Metabolome?

Role of Proteomics in COVID-19

Understanding Native Protein Characterization

Determining Proteins in Milk Using Dumas Analysis

The Human Metabolome Project

Interpreting Proteomics Data

The Role of Metabolomics in Precision Medicine

Environmental Metabolomics

How have Fluorescent Proteins Transformed Science?

Ethics in Clinical Proteomics

Studying the Metabolic Pathways Between Tissues

How do we Radiolabel Proteins?

What Role do Proteins Play in Disease?

Global Market Overview: Metabolomics

Investigating the Evolution of Microbiome Science

Importance of Lipidomics in Stem Cell Research

Omics Approaches to Biomarker Analysis

Compound Identification for Nontargeted Metabolomics

Using Omics to Harness the Power of Personalized Nutrition

Quantifying Protein Diversity: Using DIA-MS to Measure Post-Translational Modifications

What is 'Bottom-Up' Proteomics?

Cytometric Bead Arrays: A Breakdown of the Technique

How are the Metabolome and Proteome Related?

Effects of Filtered Coffee on Plasma Metabolites

What is Immunoliposome Therapy?

Racial Differences in Protein Biomarkers

What is 4D Proteomics?

Applications of Peptidomics

Role of Proteomic Analysis in Skin Regeneration

The Steps of Protein Synthesis

Combating Infectious Diseases Through Computational Protein Design

Combating Counterfeit Green Tea with Metabolomic Profiling

How Can Proteins Help Organisms to Tell the Time?

How is Omics Revolutionizing Cancer Research?

Protein Degradability

What is Proteomics?

Insight into the Human Proteoform Project

Lipidomics in Food Science

Pharmacokinetics of Cannabis and its Secondary Metabolites

What is Forensic Proteomics?

Compound Identification for Nontargeted Metabolomics

What is Metabolomics?

How to Analyze Macromolecular Protein Complexes

Protein Production: Initiation, Elongation and Termination

What is Single-Cell Proteomics?

Latest Proteomics, Metabolomics and Lipidomics News and Research

The First Parent-Of-Origin Gene Atlas of The Mammary Gland

This study maps dynamic gene expression in mouse mammary glands, revealing insights into lactation, maternal health, and breast cancer risk through imprinting.

18 Sep 2025

CRISPR Breakthrough Makes Cacao Plants More Resistant To Deadly Disease

This study shows CRISPR-Cas9 modifications to the TcNPR3 gene in cacao reduce Phytophthora susceptibility, supporting eco-friendly agricultural practices.

17 Sep 2025

Microarray Profiling Identifies LINC00974 as a Sensitive Marker for Breast Cancer Risk

In the post-genomic era, long non-coding RNAs (lncRNAs) have emerged as critical regulators in various cancers and hold potential as minimally invasive diagnostic biomarkers.

16 Sep 2025

Soil DNA Reveals Hundreds of Unknown Bacterial Genomes

Most bacteria cannot be cultured in the lab-and that's been bad news for medicine. Many of our frontline antibiotics originated from microbes, yet as antibiotic resistance spreads and drug pipelines run dry, the soil beneath our feet has a vast hidden reservoir of untapped lifesaving compounds.

16 Sep 2025

Study Reveals Stabilizing Effect of Small Molecules on Proteins

For decades, amino acids have been added to medical formulations like insulin as stabilizers: these small molecules keep proteins (i.e. larger particles) from interacting in undesirable ways.

16 Sep 2025

Microbial Molecule Controls Cancer Progression and Boosts Chemotherapy

An international team of scientists led by researchers from the MRC Laboratory of Medical Sciences (LMS), Imperial College London, and the University of Cologne discovered that microbes associated with tumors produce a molecule that can control cancer progression and improve chemotherapy efficacy.

15 Sep 2025

A Molecular Magnifying Glass for Tracking Protein Misfolding in Living Cells

A novel strategy developed at Rice University allows scientists to zoom in on tiny segments of proteins inside living cells, revealing localized environmental changes that could indicate the earliest stages of diseases such as Alzheimer's, Parkinson's and cancer.

15 Sep 2025

Researchers Decipher the Rules Behind Cellular Quality Control In Humans

A research team at the University of Cologne and the Max Delbrück Center in Berlin has deciphered in detail the rules behind an important mechanism of cellular quality control in humans.

13 Sep 2025

Electrical Jolt Speeds Fermentation of Food Waste into Valuable Chemicals

Adding an electrical jolt to fermentation of industrial food waste speeds up the process and increases the yield of platform chemicals that are valuable components in a wide range of products, new research shows.

13 Sep 2025

Molecular Simulations and AI Reveal Rapid Activation of Catch-Bonds Under Force

Imagine tugging on a Chinese finger trap. The harder you pull, the tighter it grips. This counterintuitive behavior also exists in biology.

13 Sep 2025

Study Identifies Dcir as a Brake on Immune Responses to Aspergillus Infection

People are exposed to millions of fungal spores every day, even potentially harmful ones like those from Aspergillus fumigatus.

13 Sep 2025

Engineered Base Editor Corrects ACTA2 Mutation in Rare Childhood Disease

Multisystemic smooth muscle dysfunction syndrome (MSMDS) is a rare condition associated with stroke, aortic dissection (tearing) and death in childhood.

13 Sep 2025

Built Oral Biofilm Models Reveal How Peri-Implantitis Develops

The study establishes in vitro biofilm models, revealing key insights into dysbiosis in peri-implantitis and paving the way for diagnostic advancements.

12 Sep 2025

Understanding How Bacteria Exploit Plant Growth Hormones to Attack Crops

Aphids, grasshoppers and other bugs aren't the only pests that can quickly wipe out a crop. Many harmful bacteria have evolved ways to bypass a plant's defenses.

11 Sep 2025

Specialized Protein Structures Essential for Correct Sperm Function

There are many potential causes of infertility, and it can be challenging to pin down just what the problem is when a couple is having trouble getting pregnant.

11 Sep 2025

PhoBITs Enable Unprecedented Control of Cellular Pathways with Blue Light

Imagine being able to flip a light switch to control disease pathways inside a living cell. A team of visionary researchers at the Texas A&M University Health Science Center (Texas A&M Health) is making this dream a reality with their groundbreaking genetic tools known as photo-inducible binary interaction tools, or PhoBITs.

10 Sep 2025

Predicting Protein Metal Binding with New Artificial Intelligence Model

Biologists and computational scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory recently refined two artificial intelligence (AI) programs originally built by Meta, the company that owns Facebook, to predict protein shapes.

10 Sep 2025

New Method Discovers Genetic Switches More Quickly

Researchers led by Dubravka Vučićević at the Max Delbrück Center have developed a new method for discovering how DNA controls genes. Published in “Cell Genomics,” their technique can reveal the genetic “switches” that regulate important genes more quickly than existing methods.

10 Sep 2025

Tracing Origins of Wnt Signaling Through the Lipocone Superfamily

Researchers have described a large set of previously unrecognized enzymatic domains – named the Lipocone superfamily – and outlined their evolutionary pathway from bacterial defense molecules to key players in human development.

10 Sep 2025

Scientists Engineer E. Coli To Produce Plastic-Building Chemical

This study reveals a novel pathway in E. coli for synthesizing 2,5-pyridinedicarboxylate from glucose, offering a sustainable alternative to fossil fuels.

10 Sep 2025