Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Automated 15-minute, Aseptic Micro-Sampling of T Cells

Auto-CeSS is an automated system for aseptic 30 μL sample collection, enhancing process monitoring and reducing contamination in cell therapy manufacturing.

13 Aug 2025

Muscle Reprogramming Protein Found to Both Activate and Repress Genes

For more than 30 years, scientists have studied how the myogenic determination gene number 1 (MYOD) protein binds DNA to modify the gene expression of muscle stem cells.

11 Aug 2025

Atomic-Level Models Reveal New Class Of Protein Misfolding

New computer simulations that model every atom of a protein as it folds into its final three-dimensional form support the existence of a recently identified type of protein misfolding.

11 Aug 2025

Plant Genetics Research Reveals Dynamic and Diverse Centromere Behavior

Cell division is an essential process by which living organisms grow, replenish lost cells, and regenerate dead and damaged tissues.

8 Aug 2025

New RNA Sequencing Technology Uncovers Molecular Drivers of Cellular Differentiation

Researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, have documented their use of a new RNA sequencing technology to uncover molecular drivers of cellular differentiation that could lead to better regenerative therapies.

8 Aug 2025

New Imaging System Reveals Cellular Activity at Unprecedented Depths

Both for research and medical purposes, researchers have spent decades pushing the limits of microscopy to produce ever deeper and sharper images of brain activity, not only in the cortex but also in regions underneath such as the hippocampus.

8 Aug 2025

Integrating Microfluidics and Mass Spectrometry to Unlock Cellular Complexity

Understanding cellular heterogeneity is essential for deciphering the complexities of cellular subpopulations, differentiation processes, and microenvironmental influences.

8 Aug 2025

Mapping T Cell Targets to Fight Coronaviruses and Beyond

Most vaccines are designed to provide immunity against just one pathogen. Vaccines for chicken pox (caused by varicella-zoster virus) were only developed to fight that one disease, for example.

8 Aug 2025

Salk Scientists Use CRISPR to Uncover Microproteins Linked to Obesity

The obesity rate has more than doubled in the last 30 years, affecting more than one billion people worldwide.

8 Aug 2025

Smaller Scale Mutations in HNF1A Gene Nudge Millions Toward Type-2 Diabetes

Mutations in a single gene, HNF1A, are known to cause MODY3, a rare, early onset form of diabetes.

7 Aug 2025

Microglia Replacement Therapy Offers Hope for Genetic Disorders Affecting the Brain

Tay-Sachs and Sandhoff diseases, genetic disorders affecting the brain, have no effective treatment and are typically fatal within the first years of life.

7 Aug 2025

Parkinson’s Gene Mutation Blocks Vital Neuroprotective Signals

GBA1 mutations impair ciliary Hedgehog signaling in Parkinson's disease, reducing neuroprotective factors and highlighting a shared pathogenic pathway.

7 Aug 2025

Ribosome Levels Drop During Early Brain Development

A team led by UT Southwestern Medical Center scientists has identified a specific stage of neurodevelopment when differentiating neural cells produce fewer ribosomes, which are responsible for making proteins.

6 Aug 2025

Uncovering How Cells Precisely Control Protein Production

It's known as biology's central dogma: All living organisms' genetic information is stored in DNA, which is transcribed into RNA, which is translated into proteins that perform nearly all essential tasks in a cell.

6 Aug 2025

Simple Peptides Mimic Natural Protein Protection to Revolutionize Biomolecule Stability

A new study from researchers at the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) reveals that extremely simple peptides can mimic a biological process that protects sensitive proteins from environmental stress.

6 Aug 2025

Case Western Researchers Use Stem Cells to “Shut Off” Nerve Cell Strain

Amyotrophic lateral sclerosis (ALS), sometimes known as Lou Gehrig’s disease, is an incurable neurological disease that affects motor neurons, which are nerve cells in the brain and spinal cord that regulate voluntary muscle movement and breathing.

6 Aug 2025

Prime Editing Reverses Symptoms of Severe Childhood Neurological Disease

Scientists use a precise form of gene editing called prime editing to correct the most common genetic mutations that cause alternating hemiplegia of childhood, a rare and severe neurological disorder that begins in infancy.

From The Jackson Labs 6 Aug 2025

CD276 Antibody Strategy Offers Hope For Immune-Resistant Lung Tumors

The study highlights 8H8_SDIE's role in activating NK cells against NSCLC, offering a new strategy for patients resistant to conventional immunotherapies.

6 Aug 2025

New PCE Systems Enable Precise Genome Engineering Across Kilobase to Megabase Scales

A team of Chinese researchers led by Prof. GAO Caixia from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has developed two new genome editing technologies, known collectively as Programmable Chromosome Engineering (PCE) systems.

5 Aug 2025

Small Protein LptM Plays Key Role in Assembling Protective Outer Membrane in Bacteria

Gram-negative bacteria pose a significant threat to global health due to their high resistance to antibiotics compared to that of Gram-positive bacteria.

5 Aug 2025