Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

New Research Explains How Alcohol Inhibits Gut Health

Alcohol-associated liver disease (ALD) is a leading cause of liver transplantation and mortality globally, and its effect is only increasing.

27 Aug 2025

How Defined Microbes Decide Chocolate Flavor

This study links microbial activity and fermentation conditions to cocoa flavor profiles, advancing techniques for producing premium chocolate consistently.

27 Aug 2025

New Imaging Method Reveals Lipid Distribution in Tiny Worms with High Precision

Understanding how fat molecules are distributed and function in living organisms is key to uncovering mechanisms of aging, disease, and metabolism.

25 Aug 2025

Scientists Use Single-Cell Proteomics to Track Blood Cell Differentiation

In the past decade there has been significant interest in studying the expression of our genetic code down to the level of single cells, to identify the functions and activities of any cell through the course of health or disease.

25 Aug 2025

Exploring the Regulatory Potential of "Junk DNA"

The non-coding genome, once referred to as "junk DNA," is now understood to be a fundamental regulator of gene expression and a key factor in understanding complex diseases.

25 Aug 2025

Genome-Wide Screening Approach Uncovers Genetic Brakes on Blood Cancer Growth

Australian researchers have used an innovative genome-wide screening approach to identify genes, and their encoded proteins, that play critical roles in the prevention of lymphoma development, revealing new potential treatment targets for these blood cancers.

22 Aug 2025

Ancient Interbreeding Provided Modern Humans with Useful Genetic Variation

A new study provides fresh evidence that ancient interbreeding with archaic human species may have provided modern humans with genetic variation that helped them adapt to new environments as they dispersed across the globe.

22 Aug 2025

Discovery of Lysosomal Vacuolation Mechanism Sheds Light on Aging and Disease

New research, published today in the journal Science, shows how lysosomes - organelles that act like cells' waste disposal system - respond to stress by becoming abnormally bloated, a process called lysosomal vacuolation that is associated with numerous diseases.

22 Aug 2025

Breakthrough Technique Enables Large-Scale Study of Polar and Ionic Metabolites

Researchers from the McCullagh Group in Oxford University's Department of Chemistry have published an innovative method in Nature Protocols today (22 August) that provides comprehensive analysis of metabolites found in cells, tissues and biofluids.

22 Aug 2025

Epigenetic Noise Enables Cells to Shift Identity and Influence Immunity

All cells in the body contain the same DNA, but different cell types express different genes; skin cells express genes for the skin, liver cells express liver genes, and so on.

21 Aug 2025

Computational Modeling Creates a Database for Improved Detection of Designer Drugs

How do you identify something no one has a test for? Designer drugs replicate the effects of known, illicit drugs but evade law enforcement.

21 Aug 2025

How Primary Cilia Shape the Fate of Fat Precursor Cells

Too much fat can be unhealthy: how fat cells, so-called adipocytes, develop, is crucial for the function of the fat tissue.

21 Aug 2025

New Tool Offers Insight Into When Genes Turn On and Off in the Brain

A Yale research team has created a new computer tool that can pinpoint when exactly genes turn on and off over time during brain development - a finding that may one day help doctors identify the optimal window to deploy gene therapy treatments.

20 Aug 2025

New Technology Maps Over 140 Proteins Across Human Tissues

Each organ in the human body contains different types of cells arranged in specific ways.

20 Aug 2025

MIT Researchers Unlock the Hidden Features of Protein Language Models

Within the past few years, models that can predict the structure or function of proteins have been widely used for a variety of biological applications, such as identifying drug targets and designing new therapeutic antibodies.

20 Aug 2025

Feline Dementia May Explain Synapse Loss in Alzheimers

The study uncovers amyloid-beta's role in glial-mediated synapse loss in feline cognitive dysfunction, enhancing understanding of Alzheimer's disease.

20 Aug 2025

New Insights Reveal Bacterial Roots of Key Plant Hormone Enzymes

Terpenoids play vital roles in plant ecology-from repelling pests to attracting pollinators-and are produced by terpene synthases (TPSs) enzymes.

19 Aug 2025

Missing Microexons Disrupt Synapse-Related Proteins in Pediatric Glioma

A new study, led by researchers at Children's Hospital of Philadelphia (CHOP), identified tiny pieces of messenger RNA that are missing in pediatric high-grade glioma tumors but not in normal brain tissues.

19 Aug 2025

Amino Acids as Key Mediators in the Tumor Immune Dialogue

The tumor microenvironment is not just a site of cancer growth—it is a high-stakes metabolic contest where tumor and immune cells vie for limited resources.

19 Aug 2025

New Enzyme Technology Illuminates Hidden Sugar Patterns on Cells

Sugars known as glycans form dense envelopes around cells. But they're often ignored in biological investigations because, unlike DNA, proteins and other cellular components, tools to study them are lacking.

18 Aug 2025