Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

New computational tool for long-read RNA sequencing

An evolving RNA molecule can be cut and joined, or spliced, in various ways on the path from gene to protein before being translated into a protein. Using a technique called alternative splicing, multiple proteins can be encoded by a single gene.

24 Jan 2023

Digital microbe database unlocks patient response to treatment

Scientists at the University of Galway, in collaboration with APC Microbiome Ireland, a world-class SFI Research Centre, have developed a database of over 7,000 digital microbes, allowing computer simulations of how drug treatments operate and how patients may respond.

24 Jan 2023

Ubiquigent collaborates with University of Glasgow on translational structural biology to accelerate drug discovery within the (de)ubiquitylation field

Ubiquigent Limited (Ubiquigent), a drug discovery and development company harnessing novel deubiquitinase (DUB) modulators as new therapeutics for areas of high unmet medical need, today announced it is supporting a Master’s student at the University of Glasgow (UoG) to undertake a research project on USP30, a DUB implicated in neurodegenerative, renal, and cardiovascular diseases.

From Ubiquigent Limited 23 Jan 2023

Study reveals how complex carbon and nutrient sources are metabolized by interacting microbes

Interactions among microorganisms in soil lead to the release of nutrients derived from complex organic matter in that soil.

20 Jan 2023

How do methanogens grow on toxic sulfite?

Methanogens are microbes that produce methane when there is little or no oxygen in their surroundings.

From The Max Planck Institute 20 Jan 2023

New center to assist in understanding non-coding cancer genome

The MacMillan Center for the Study of the Non-Coding Cancer Genome (MCSNCG) was officially launched by the New York Genome Center (NYGC) on January 18th, 2023.

19 Jan 2023

Molecular mechanism behind microtubule dynamics in R. contractilis

Raphidocystis contractilis belongs to Heliozoa, a group of eukaryotes that is generally seen in brackish, fresh, and seawater.

19 Jan 2023

Potential to rectify various disease-causing mutations enhanced by CRISPR-based enzymes

Designing genome editing strategies for each patient’s mutation would be impractical and expensive because many genetic diseases are induced by diverse mutations spread across an entire gene.

18 Jan 2023

Using fungi to transform ocean plastic waste into key pharmaceutical components

Research on fungi underway at the University of Kansas has helped transform tough-to-recycle plastic waste from the Pacific Ocean into key components for making pharmaceuticals.

18 Jan 2023

Role of clonal hematopoiesis as a broad driver of atherosclerosis

A group at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), collaborating with institutions in the USA, has shown that acquired mutations in the gene encoding the protein p53 contribute to the onset of atherosclerotic cardiovascular disease.

18 Jan 2023

Grasping how a biological pathway causes stem cells to regenerate or die

According to a recent study conducted by Cedars-Sinai and the University of California, San Francisco (UCSF), altering a cellular process can cause stem cells, which are the cells that give rise to all other types of body cells, to either die or regenerate.

18 Jan 2023

Electrochemical biosensor for detecting antibodies

Although it frequently necessitates a challenging laboratory procedure, the quantitative detection of specific antibodies in complex samples like blood can provide information on a variety of diseases.

18 Jan 2023

Innovative approach to mRNA delivery

A group of scientists spearheaded by The University of Texas MD Anderson Cancer Center has created a unique messenger RNA (mRNA) delivery system utilizing extracellular vesicles (EVs).

16 Jan 2023

Study suggests new strategies for controlling plant biochemistry

Plant biochemists at the U.S. Department of Energy's Brookhaven National Laboratory have discovered a new level of regulation in the biochemical "machinery" that plants use to convert organic carbon derived from photosynthesis into a range of ring-shaped aromatic molecules.

12 Jan 2023

The continued functioning of circadian clock of cells even after starvation

According to a study that was just published in eLife, cells that have a functioning molecular clock are better able to adapt to changes in glucose supply and can recover from long-term starvation more quickly.

11 Jan 2023

Analyzing the regulatory mechanisms of enzyme production in mold

Filamentous fungi have long been a close ally of sake brewers, but they may soon become associates of environmentalists as well. Scientists from Osaka Metropolitan University discovered the regulatory mechanisms of enzyme synthesis in a filamentous fungus, allowing for the effective degradation of plant biomass, an alternative energy resource to petroleum.

11 Jan 2023

New gene helps drive the development of the common lung cancer type

At the NYU Langone Health’s Perlmutter Cancer Center, a team headed by scientists has determined a gene that forces the development of the second most common type of lung carcinoma.

From New York University (NYU) 11 Jan 2023

New open-access database provides a map of the proteome signature

The recently released cancer protein profile database, which was created using AI and machine learning, has helped with cancer prediction medicine. The new open-access Disease Blood Atlas, unveiled by KTH Royal Institute of Technology Professor Mathias Uhlén, gives the first-ever map of the proteome signature in cancer patients’ blood.

11 Jan 2023

Effective anticancer strategy for selective killing of cancer cells

A study team headed by Dr Yuanliang Zhai from The University of Hong Kong’s (HKU) School of Biological Sciences and his associates from The Hong Kong University of Science and Technology (HKUST) and Institut Curie in France discovered a new mechanism of the human MCM2-7 complex in controlling replication initiation, which can be employed as a unique and effective anticancer method with the potential for selective death of cancer cells.

11 Jan 2023

Chilling tolerance trait in rice with the codon repeats at a single site

A recent study performed by Professor Chong Kang’s group from the Institute of Botany of the Chinese Academy of Sciences (CAS) has disclosed a fact that a novel cold domesticated repair mechanism for DNA damage in rice.

11 Jan 2023