Clinical biobanks that combine genomic data with electronic health records (EHRs) have become powerful resources for discovering genetic variants associated with disease.

28 Jul 2026

Scientists Discover Molecular Mechanism Behind Red and Green Color Vision

Human color vision depends on three types of cone cells in the retina. Although all three contain the same light-absorbing molecule, 11-cis-retinal, differences in the surrounding protein determine sensitivity to red, green, or blue light.

28 Jul 2026

Dengue Virus Replicates Inside Memory B Cells to Evade Immunity

Researchers at the University of Vermont Robert Larner, M.D. College of Medicine and Upstate Medical University in Syracuse, NY, have discovered that dengue virus can infect and replicate inside memory B cells, immune cells traditionally understood to help protect the body from infection.

28 Jul 2026

Research Decodes How Gut Microbes Process Plant-Based Nutrients

Plant-based diets are good for you. They promote gut, immune, metabolic and cardiovascular health, in part by cultivating a diverse community of intestinal bacteria.

28 Jul 2026

3D Mapping of Tonsil Genetic Structures Unlocks Antibody Optimization

About 2 meters worth of genetic material must fit into the nucleus of each and every one of most of our trillions of cells, coiling and winding to form what looks like a tangled mess.

28 Jul 2026

Molecular Insights Into Fungal Effectors Disabling Host Immune Transcription Factors

Plants defend themselves through a layered innate immune system: pathogen-associated molecular pattern-triggered immunity (PTI) and effector-triggered immunity (ETI), mediated by pattern recognition receptors (PRRs) and nucleotide-binding leucine-rich repeat (NLR) receptors, respectively.

28 Jul 2026

Uncovering Plant Discrimination and Dose Responses to Beneficial Soil Microbes

For years, beneficial Bacillus bacteria have been used to promote plant growth and protect crops, yet most studies treat these microbes as functionally interchangeable.

28 Jul 2026

Type I CRISPR Systems Regulate Embedded Innate Immunity Genes in Neisseria

The main function of CRISPR-Cas systems, the revolutionary tool scientists now employ to edit genes, is to defend bacteria against threats such as viruses called bacteriophages. Researchers have continued to study all flavors of CRISPR-Cas systems (to date, 2 classes, 7 types and 46 subtypes have been identified) to understand all their capabilities.

27 Jul 2026

Study Uncovers Two Distinct Embryonic Macrophage Populations with Different Repair Abilities

In leukemia's most aggressive forms, the blood cell factories in our bone marrow falter. Instead of dividing and multiplying at their usual prolific pace, generating hundreds of billions of new cells daily, some precursor cells stall out at an immature stage.

27 Jul 2026

Engineered Probiotic Bacteria Deliver Immune Therapy Directly Into Pancreatic Tumors

Cancer immunotherapies have transformed treatment for many cancers, but pancreatic cancer remains especially difficult to treat. One major reason is that pancreatic tumors often create a "cold" tumor microenvironment, where the tumor prevents immune cells from mounting a strong attack.

27 Jul 2026

Synthetic Biology Breakthrough Rebuilds Basic Features of Cellular Life

Nature is beautiful, powerful and essential. But nature is not always gentle. The same biological world that gives rise to forests, coral reefs and human life also produces infections, cancer, genetic disease, crop blights and toxins.

24 Jul 2026

Scientists Uncover Unexpected Mechanism Behind Extreme Antibiotic Resistance

A patient with a severe infection is prescribed a potent antibiotic. Hopes for improvement are high, but just after treatment is given, resistance to the drug increases thousands of times. How could this happen?

24 Jul 2026

New Research Links CALB2 Gene to Mechanoresistance in Metastatic Prostate Cancer

When a cancer cell leaves the original tumor to spread to a new, far away location, it first has to survive what most cells cannot: periodic high force moments in the vessels and heart of up to 5,000 dynes per centimeter squared as it circulates throughout the body.

24 Jul 2026

Study Reveals How Genome Regulation Changes During Brain Aging

Researchers have discovered that the human brain undergoes widespread age-related changes in genome regulation beginning in midlife that may help explain why aging is the greatest risk factor for neurodegenerative diseases such as Alzheimer's.

24 Jul 2026

AI-Assisted Protein Tools Guide Design of Synthetic Plant Immune Receptors

Crop production faces threats from plant pathogens. Traditional disease-resistance breeding relies heavily on natural plant resistance genes that encode immune receptors adapted to particular pathogens.

24 Jul 2026

Scientists Discover Altered 3D Genome Structure in Alzheimer’s Brains

Researchers from Carnegie Mellon University's School of Computer Science, the University of Pittsburgh School of Medicine and the University of Washington shed new light on Alzheimer's disease that could point to new directions for treatment.

24 Jul 2026

Researchers Find New Bacterial Mechanism for Evading Antibiotic Exposure

Antibiotics are a medical marvel, but many microbes are gaining the ability to resist and tolerate these therapeutics.

24 Jul 2026

Chemotherapy Leaves Distinct DNA Changes in Childhood Tumors

Nearly half of childhood tumors treated with common types of chemotherapy showed detectable DNA changes linked to treatment within 18 months, according to a new international study led by The Hospital for Sick Children (SickKids).

24 Jul 2026

Tapeworm Makes Ants Live Longer

A tapeworm fundamentally changes the lives of ants: Workers of the species Temnothorax nylanderi that are infected with the tapeworm Anomotaenia brevis live several times longer than their uninfected nestmates.

24 Jul 2026

Basement Membrane Remodeling Drives Melanocyte Dedifferentiation in Vitiligo Skin Lesions

Vitiligo is an autoimmune disease in which the body's immune system attacks and destroys melanocytes, the cells that produce the skin pigment melanin. Once the melanocytes are gone, the skin turns white, leading to the characteristic skin patches of the disease.

23 Jul 2026