Chronic inflammation, indicated by GlycA levels, has been linked to heart changes and increased cardiovascular risk, highlighting genetic and environmental interactions.

25 Sep 2026

Cryo-ET Reveals Native Membrane Architecture of Synchronous RyR1 Calcium Channels

Using cryo-electron microscopy, researchers at the Max Delbrück Center have revealed how muscle cell calcium channels open synchronously. The findings, published in "Nature Communications," may explain a mechanism behind serious muscle diseases.

25 Sep 2026

Engineered E. coli Strains Validate Putrescine Uptake and Systemic Host Conversion

Gut microbiota influences multiple aspects of host physiology, including metabolic and immune functions. Many metabolites produced by gut bacteria can cross the intestinal epithelium (which the bacteria may not be able to cross) and enter host tissues, providing a pathway through which microbial activity can influence host physiology.

25 Sep 2026

3D Stem-Cell miBrains Model Complex Neurovascular Pathology in Human Tissue

Mount Sinai researchers have identified how APOE4, the strongest genetic risk factor for Alzheimer's disease, damages the brain's blood vessels and promotes the buildup of abnormal proteins linked to neurodegenerative disease.

25 Sep 2026

Cancer Cells Hijack Embryonic Repair Mechanisms to Seed Liver Metastases

Most colon cancer deaths are caused by the spread of tumor cells beyond the colon, usually to the liver. In a new study, MIT biologists identified a cellular pathway necessary for colorectal cancer metastasis.

25 Sep 2026

Multi-Receptor Blocking Achieves Superior Antifibrotic Response Over Single-Receptor Inhibition

Three adenosine receptor subtypes that normally send different signals were found to converge on a common pathway that activates cardiac fibroblasts, the scar-forming cells in the heart. Blocking the receptors together produced a much stronger antifibrotic effect than blocking them one at a time.

25 Sep 2026

Ultra-High-Resolution 3D Microscopy Captures Distinct Presynaptic Protein Organization States

A new study led by researchers at the University of Wisconsin School of Medicine and Public Health examines how different versions of the same protein can alter neuronal communication.

25 Sep 2026

Garvan Researchers Uncover Genetic Causes of Inherited Muscle Disease

A world-first test developed by researchers at the Garvan Institute of Medical Research has identified the genetic cause of inherited muscle disease in people who remained without answers after years, sometimes decades, of standard testing.

25 Sep 2026

Scientists Discover Why High Levels of the Amino Acid Cysteine Are Toxic to Cells

Cysteine is one of the main building blocks that cells use to make proteins. But this amino acid is a double-edged sword–too much cysteine is toxic to the cell.

24 Sep 2026

A Tiny Worm Helps Scientists Unravel a Genetic Clue to Kidney Disease

A microscopic worm that has no kidneys is helping Rutgers scientists understand a genetic change suspected of causing a serious inherited kidney disease.

24 Sep 2026

Study Uncovers Two-Protein Repair Mechanism Preserving Circular ecDNA Stability

Researchers at Memorial Sloan Kettering Cancer Center (MSK) and their colleagues have discovered that a type of rogue DNA found in aggressive cancers has a hidden structural weakness - and that blocking a single repair protein can cause it to fall apart, suggesting a new therapeutic opportunity.

24 Sep 2026

Trans-spliceosome Architecture Maps Evolutionary Divergence in Eukaryotic RNA Processing

A study conducted between the University of Liège and Rockefeller University reveals, with near-atomic precision, the three-dimensional structure and function of a gigantic molecular machine essential to the survival of trypanosomatid parasites, which cause serious diseases in humans, animals and plants.

24 Sep 2026

Researchers Simulate Microgravity to Isolate Gravity's Impact on Human Chromatin

The Human Genome Project was launched in 1990, preceded by decades of breakthroughs in genetics. It eventually gave us a sequence of the human genome.

24 Sep 2026

Latent HIV Viral Proteins Drive Persistent Low-Grade Brain Inflammation During ART

Antiretroviral drugs let people with HIV live full-length lives, but cognitive problems often persist. Some studies have found cognitive impairment in as many as half of people receiving antiretroviral therapy, although estimates vary and many cases do not interfere with daily activities.

24 Sep 2026

Phage Tail Fiber Flexibility Bypasses Bacterial Immune Evasion Through Pili Diversification

Bacteriophages - or phages, for short - are viruses that kill bacteria, and scientists have been studying them for decades as a possible solution to antibiotic-resistant infections.

24 Sep 2026

Cambridge Researchers Look Inside Living Antarctic Cells for First Time

Engineers have built the first microscope to see inside living cells in sub-zero conditions, revealing secrets of Antarctic fish survival.

23 Sep 2026

Strength Training Induces Fat Breakdown in Obese Mice Without Weight Loss

Just seven days of strength training increased visceral fat burning in obese mice, even before any weight loss could be seen on a scale. In an experiment conducted at the State University of Campinas (UNICAMP), researchers observed that a short period of strength training activated mechanisms involved in fat breakdown, reduced fat cell size, and decreased fat around the animals' intestines.

23 Sep 2026

KAIST Researchers Develop NUDGE to Steer Cell States Without Permanent Alteration

Which genes need to be controlled to guide a stem cell toward a desired cell type, or to modulate an immune cell's inflammatory response? A Korean research team has developed a general-purpose computational framework that identifies the key targets needed to steer a cell toward a desired state with a single temporary intervention, without permanently altering its genes.

23 Sep 2026

Mitochondrial RNA May Explain How Tumors Become Resistant to Immunotherapy

Research highlights mitochondrial RNA's influence on interferon signaling, linking chronic exposure to tumor growth and offering new avenues for immunotherapy.

22 Sep 2026