Cysteine is one of the main building blocks that cells use to make proteins. But this amino acid is a double-edged sword–too much cysteine is toxic to the cell.

24 Sep 2026

A Tiny Worm Helps Scientists Unravel a Genetic Clue to Kidney Disease

A microscopic worm that has no kidneys is helping Rutgers scientists understand a genetic change suspected of causing a serious inherited kidney disease.

24 Sep 2026

Study Uncovers Two-Protein Repair Mechanism Preserving Circular ecDNA Stability

Researchers at Memorial Sloan Kettering Cancer Center (MSK) and their colleagues have discovered that a type of rogue DNA found in aggressive cancers has a hidden structural weakness - and that blocking a single repair protein can cause it to fall apart, suggesting a new therapeutic opportunity.

24 Sep 2026

Trans-spliceosome Architecture Maps Evolutionary Divergence in Eukaryotic RNA Processing

A study conducted between the University of Liège and Rockefeller University reveals, with near-atomic precision, the three-dimensional structure and function of a gigantic molecular machine essential to the survival of trypanosomatid parasites, which cause serious diseases in humans, animals and plants.

24 Sep 2026

Researchers Simulate Microgravity to Isolate Gravity's Impact on Human Chromatin

The Human Genome Project was launched in 1990, preceded by decades of breakthroughs in genetics. It eventually gave us a sequence of the human genome.

24 Sep 2026

Latent HIV Viral Proteins Drive Persistent Low-Grade Brain Inflammation During ART

Antiretroviral drugs let people with HIV live full-length lives, but cognitive problems often persist. Some studies have found cognitive impairment in as many as half of people receiving antiretroviral therapy, although estimates vary and many cases do not interfere with daily activities.

24 Sep 2026

Phage Tail Fiber Flexibility Bypasses Bacterial Immune Evasion Through Pili Diversification

Bacteriophages - or phages, for short - are viruses that kill bacteria, and scientists have been studying them for decades as a possible solution to antibiotic-resistant infections.

24 Sep 2026

Cambridge Researchers Look Inside Living Antarctic Cells for First Time

Engineers have built the first microscope to see inside living cells in sub-zero conditions, revealing secrets of Antarctic fish survival.

23 Sep 2026

Strength Training Induces Fat Breakdown in Obese Mice Without Weight Loss

Just seven days of strength training increased visceral fat burning in obese mice, even before any weight loss could be seen on a scale. In an experiment conducted at the State University of Campinas (UNICAMP), researchers observed that a short period of strength training activated mechanisms involved in fat breakdown, reduced fat cell size, and decreased fat around the animals' intestines.

23 Sep 2026

KAIST Researchers Develop NUDGE to Steer Cell States Without Permanent Alteration

Which genes need to be controlled to guide a stem cell toward a desired cell type, or to modulate an immune cell's inflammatory response? A Korean research team has developed a general-purpose computational framework that identifies the key targets needed to steer a cell toward a desired state with a single temporary intervention, without permanently altering its genes.

23 Sep 2026

Mitochondrial RNA May Explain How Tumors Become Resistant to Immunotherapy

Research highlights mitochondrial RNA's influence on interferon signaling, linking chronic exposure to tumor growth and offering new avenues for immunotherapy.

22 Sep 2026

Blocking Mitochondrial Iron Transport Protects Cells Against Elevated Cysteine Toxicity

Cysteine is one of the main building blocks that cells use to make proteins.

22 Sep 2026

Tumor Suppressor Pathways Remain Intact but Hyperactive During Progressive Tissue Aging

A new review was published in Volume 18 of Aging on August 31, 2026, titled "The guardian paradox: DNA damage response overactivation as an integrative driver of aging – a tumor suppressor–negative regulator framework."

22 Sep 2026

Breakthrough Study Explains Developmental Origins of the Human Brain

For centuries, scientists have thought of the brain as a single, unified organ. But new research led by Stanford Medicine reveals that what we call the brain is two distinct organs that evolved independently over hundreds of millions of years.

21 Sep 2026

Novel Base-Editing Approach Shows Promise for Inherited Motor Neuron Disorders

A team of researchers led by Professor Haruhisa Inoue (Center for iPS Cell Research and Application, Kyoto University) and Professor Yuishin Izumi (Tokushima University) demonstrated that adenine base editing can correct a disease-causing genetic mutation and alleviate neurodegeneration in hereditary motor and sensory neuropathy with proximal dominant involvement (HMSN-P), providing proof of concept for a precision gene therapy for inherited motor neuron diseases.

21 Sep 2026

Study Maps Precise Anatomical Circuits Within the Brainstem Locus Coeruleus

Deep in the brainstem sits a small but important cluster of neurons known as the locus coeruleus (LC), Latin for "blue place."

21 Sep 2026

New Research Reveals Complex Protein Dynamics Within Human Red Blood Cells

They account for nearly 83% of all cells in the human body, yet red blood cells are often portrayed as little more than bags of hemoglobin ferrying oxygen from the lungs to the heart and beyond. But new research from the University of Colorado Anschutz reveals that they are vastly more complex with far reaching consequences for health, exercise and fitness.

21 Sep 2026