With CRISPR-Cas9 technology, humans can now rapidly change the evolutionary course of animals or plants by inserting genes that can easily spread through entire populations.

29 Mar 2023

Using better probiotics to maintain a healthy gut microbiome

Bacteria have thousands of genes and functions that we, the human host, do not have. For instance, bacteria can help us digest fiber, provide support to our immune systems, and absorb important nutrients. But reaping the benefits of "good bacteria" is easier said than done.

29 Mar 2023

Study provides a feasible tool to evaluate vesicular endocytosis of NPC1L1-cargos and cholesterol absorption

Excessive cholesterol absorption from intestinal lumen contributes to the pathogenesis of hypercholesterolemia, which is a well-established risk factor for atherosclerotic cardiovascular disease.

29 Mar 2023

New DNA editing tool could rapidly accelerate the design of custom microbes

A DNA editing tool adapted by Oak Ridge National Laboratory scientists makes engineering microbes for everything from bioenergy production to plastics recycling easier and faster.

29 Mar 2023

Evolution driven by genetic engineering should be known as ‘genetic welding’ to draw scientific and ethical scrutiny

In an opinion paper, evolutionary geneticist Asher Cutter highlights the importance of coining the term ‘genetic welding’ for the anthropogenic manipulation of genetic drive made possible by tools such as CRISPR-Cas9.

29 Mar 2023

Analyzing the GmZF351 transgenic soybean plants and their stress tolerance

Across the globe, soybean is considered to be an important food, oil, and feed crop worldwide.

29 Mar 2023

New project addresses the lack of standards for optimal management of Lp(a)

According to a recent scientific statement gathered from American Heart Association, high levels of lipoprotein(a) [Lp(a)] are known to be a separate, chiefly inherited and causal risk factor for cardiovascular disease, known to be the leading cause of death and disability around the world.

29 Mar 2023

The proper implementation of stem cell-based disease models

Scientists have learned how to manufacture induced pluripotent stem cells (iPSC) from regular cells through genetic reprogramming during the last ten years.

29 Mar 2023

Determining the structure of protein pumps using cryo-EM

A rare, genetic disorder known as Hailey-Hailey disease causes patches of blisters to develop mainly in the folds of skin under the breasts, in the groin, and the armpits.

29 Mar 2023

Myeloid cells contribute to a long-lived HIV reservoir, study shows

A subset of white blood cells, known as myeloid cells, can harbor HIV in people who have been virally suppressed for years on antiretroviral therapy, according to findings from a small study supported by the National Institutes of Health.

28 Mar 2023

Human cells shed light on basic squid biology

Squids and octopuses are masters of camouflage, blending into their environment to evade predators or surprise prey.

28 Mar 2023

Finding how the global regulation factor reshapes the cell-fate-decision landscape

Determining cell differentiation trajectories has been done by genes and the regulation relationships among them creating complicated networks.

28 Mar 2023

Resistance genes in human gut influenced by national trends in antibiotic consumption

According to a new study performed at the Earlham Institute and Quadram Institute in Norwich, the community of microbes living in and on human bodies might be serving as a reservoir for antibiotic resistance.

28 Mar 2023

Newest variant of mScarlet3 to help track protein movements in living cells

Biologists frequently utilize a method to figure out why a cell divides, secretes hormones, or sends a signal to another cell. They attach colored lights to the proteins of interest so that they can see their motions and interactions in living cells under a microscope.

28 Mar 2023