A clinician-led research team has developed a gene-editing platform that could give doctors more control over cell therapies, making them more practical for patients with complex immune conditions.

20 Oct 2026

Study Details Genetic Divergence Between Astrocytomas and Oligodendrogliomas

Treatment-resistant brain cancers develop different mutations as they become more aggressive, according to new research from Yale School of Medicine.

20 Oct 2026

Functional Genomics Platform Connects Candidate Genes to Pest Defense Phenotypes

Cowpea (Vigna unguiculata) supplies dietary protein, livestock feed, and income in tropical and subtropical regions, while its nitrogen-fixing ability adds agricultural value. Genome sequencing has provided researchers with numerous candidate genes, and genetic transformation has enabled studies of traits such as drought and heat tolerance.

20 Oct 2026

Dendritic Cell STING Activation Licenses Cytotoxic T Lymphocyte Priming

Immune checkpoint inhibitors (ICIs) have transformed cancer care, yet only a subset of patients benefit. A major barrier is tumor microenvironment (TME) heterogeneity: "hot" tumors are enriched with cytotoxic T lymphocytes (CTLs) and respond better, while "cold" tumors lack T-cell infiltration or are shielded by immunosuppressive barriers.

20 Oct 2026

Cold Responsive Transcription Factor Binding Overlaps Open Chromatin at Gene Promoters

Rice originated in subtropical environments, yet its cultivation has expanded into regions where low temperatures threaten growth, development, and yield. Japonica rice generally tolerates cold better than indica rice, and researchers have linked this adaptation to changes in stress-responsive gene expression. Much attention has focused on C-repeat binding factors, a group of transcription factors that help coordinate plant cold responses.

20 Oct 2026

Stable Isotope Carbon Tracing Proves Uncoupling Inhibits De Novo Purine Synthesis

Mitochondrial serine catabolic pathway (MSCP), also called serine, glycine, and one-carbon metabolism, is essential for cancer cells to produce amino acids, one-carbon units, and reducing equivalents.

20 Oct 2026

Live Organelle Imaging Catches Early Neuronal Stress Before Cell Death

Scientists studying amyotrophic lateral sclerosis (ALS), Parkinson's, Alzheimer's and other neurological diseases are getting unprecedented views inside brain cells, using powerful new microscopes to uncover changes that may begin long before neurons die.

20 Oct 2026

Mayo Clinic Study Advances Detection of Somatic DNA Mutations

Researchers in a Mayo Clinic-led study have shown how to detect a broad range of DNA mutations in noncancerous human tissues and across the genome.

16 Oct 2026

Mobile Genetic Elements and Reservoir Type Drive Resistance-Gene Abundance in Water Sources

Aquatic environments are recognized as reservoirs and pathways for antimicrobial resistance, receiving antibiotic residues and resistant microorganisms from sewage, livestock farming, and aquaculture. Previous studies have detected resistance genes in drinking water sources and shown that conventional treatment may remove them incompletely.

16 Oct 2026

Three Genes Identified to Prioritize Genetic Drug Testing in China

A research team has identified three genes that could help prioritize pharmacogenomic testing for older adults in China who receive multiple medications.

16 Oct 2026

Machine Learning Tool Pinpoints Crucial Gene Regulation Changes

Changes in our genes affect health risks from heart disease to cancer, but how those genes are turned on and off is just as crucial to health.

16 Oct 2026

Novel Molecular Pathway Identified to Combat T-Cell Exhaustion in Cancer

Researchers at the UCLA Health Jonsson Comprehensive Cancer Center used a CRISPR screen to identify a key molecular pathway that drives exhaustion in cancer-fighting immune cells, limiting their ability to keep tumors under control.

16 Oct 2026

Could mRNA Vaccine Technology Help Repair Damaged Livers?

Research indicates that brief cellular reprogramming and mRNA nanoparticles can enhance liver repair, offering new strategies for acute liver injury recovery.

16 Oct 2026

Cell Division Actively Reshapes Crowded Epithelial Tissue, Study

Every time a tissue grows or renews itself, cells must divide inside an already crowded environment.

16 Oct 2026

Plant Circadian Clock Drives Molecular Salt Stress Defenses

Salty soil is a growing threat to crops worldwide. Hotter, drier weather has increased evaporation rates, drawing moisture from the soil and leaving behind concentrated mineral salts.

16 Oct 2026

Artificial Intelligence Integrates Multi-Omic Data to Predict HPV Lesion Progression

Infection with human papillomavirus (HPV) is extremely common and, in the vast majority of cases, clears up on its own. However, in some people, it persists and can develop into precancerous lesions or even cancer.

16 Oct 2026

Scientists Discover Molecular Chain Reaction Behind Sound Wave Healing

Researchers from Capital Medical University, Beijing, China, have identified a CaN/NFATC3/Id3/E2A/Bmp4 signaling pathway that helps explain how low-intensity pulsed ultrasound (LIPUS) promotes bone regeneration.

16 Oct 2026

Non-Dominant Bacterial Networks Drive Stability and Resilience in Gut Microbiome

The stability of the human gut microbiome relies on interactions between different bacterial species. However, the specific molecular mechanisms of these interactions, particularly among non-dominant species, remain largely unexplored.

16 Oct 2026

Genomic Adaptation Reveals How Candida auris Resists Potent Antifungal Drug Treatments

New research has revealed an unexpected new mechanism through which the killer fungus Candida auris is resisting antifungal drug treatment.

15 Oct 2026

Gene Amplification Unexpectedly Increases Bacterial Susceptibility to Frontline Antibiotics

This study was led by Yuqin Song and Jie Feng from the Institute of Microbiology, Chinese Academy of Sciences. The researchers investigated how insertion sequence (IS)-mediated gene amplification contributes to the adaptability of Acinetobacter baumannii, an important nosocomial pathogen known for its multidrug resistance and persistence in clinical environments.

15 Oct 2026