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How the Microbiome Shapes Cancer Immunity and Therapy Response

This review examines how the human microbiome regulates anti-tumor immunity through DNA damage, inflammation, immune-cell activity, microbial metabolites, and tumor microenvironment remodeling. It highlights emerging microbiome-based strategies, including FMT, probiotics, prebiotics, engineered bacteria, and live biotherapeutics, while stressing the need for rigorous validation and clinical trials.

29 Apr 2026

New Pipeline Sharpens Single-Cell Profiling of CAR Immune Therapies

CERTOMICS is a Nextflow-based computational pipeline designed to identify and profile CAR-engineered immune cells using single-cell multiomics data. By integrating gene expression, immune receptor profiling, protein markers, CAR-aware references, and CAR-specific quality control, it supports more standardized analysis of adoptive cellular immunotherapies.

29 Apr 2026

Hackensack Meridian Center for Discovery and Innovation Enhances Skin Fibrosis Research with Efficient Serological Pipet Controller

Researchers at Hackensack Meridian Center for Discovery and Innovation (CDI) are using the PIPETBOY GENIUS serological pipet controller from INTEGRA Biosciences to enhance the efficiency of biomarker research for skin fibrosis.

From INTEGRA Biosciences 29 Apr 2026

New Pistoia Alliance Poll Finds Regulatory Teams Benefit Most from AI, But Just 1 % See Value in the Wet Lab

The Pistoia Alliance, a global, not-for-profit that advocates for greater collaboration in life sciences R&D, has released new poll data from its annual European conference, revealing that while AI use is becoming widespread across life sciences organizations, its measurable impact on drug R&D remains limited.

From The Pistoia Alliance 29 Apr 2026

Magnetic Microrobots That Could Transform Cancer Treatment

Cancer treatments and other delicate medical procedures might one day be performed using tiny microrobots that are precisely directed within the body, according to a new magnetic tool created by scientists.

29 Apr 2026

Proxygen Expands Platform Beyond Degradation to Build Next-Generation Induced Proximity Therapeutics

Proxygen, a biotechnology company pioneering the discovery of molecular glue degraders and next-generation proximity-based therapeutics, today publicly announced the expansion of its platform beyond targeted protein degradation to access a broader range of induced proximity therapeutics, while advancing two lead molecular glue degrader programs toward clinical development.

From Proxygen 29 Apr 2026

Intermediate PRRX1 Levels Drive Breast Cancer Metastasis Risk

The study identifies PRRX1 as a critical factor in breast cancer metastasis, highlighting its potential as a biomarker for predicting aggressive disease.

29 Apr 2026

Drug Development: Development of Dextran Nanoparticles for Stabilizing Delicate Proteins

Nanoscale Research Letters, an open access journal published under Springer Open, presented a study entitled "Development of Dextran Nanoparticles for Stabilizing Delicate Proteins." In this study, a Brookhaven NanoBrook 90Plus Particle Size Analyzer was used to help develop a novel approach to stabilize and encapsulate proteins into dextran nanoparticles.

From Brookhaven Instruments 29 Apr 2026

New DNA Tests Expose Spice Fraud Across Popular Herbs and Spices

Researchers interlaboratory-validated 13 DNA-based qPCR methods to quantify selected plant adulterants in paprika/chilli, saffron, turmeric, cumin, oregano, and black pepper. The methods showed strong repeatability, reproducibility, and trueness, supporting their use as confirmatory tools in official spice authenticity testing.

28 Apr 2026

MD Anderson Researchers Map DNA Replication Stress at Single-Cell Resolution

Researchers at The University of Texas MD Anderson Cancer Center have developed a new imaging method, known as RF-SIRF, that quantitatively detects and maps reversed DNA replication forks with single-cell resolution.

28 Apr 2026

High Resolution Images Reveal DNA Repair Process in Key Protein

Scientists have captured the most detailed structural images to date of a specific type of protein's DNA repair process, a finding that could reveal ways to inhibit the effects of BRCA1 and BRCA2 mutations that heighten the risk for breast, ovarian and other cancers.

28 Apr 2026

Protein Adgrl2 Regulates Brain Synapses and Blood Vessel Integrity

The communication network in the developing brain builds when neurons partner up to form contact points called synapses, allowing signals to pass form one cell to another.

28 Apr 2026

Obesity Leaves Persistent Epigenetic Marks on Immune Cells

People who live with obesity are 'tagging' a memory of being overweight on a key part of the immune system - leaving people with ongoing risk of obesity-related conditions years after losing weight, according to a 10 year-long study published in EMBO Reports.

28 Apr 2026

Key Protein Switch Activates Leptospira Virulence and Disease Spread

During infection, pathogens must adapt quickly to the conditions to thrive inside the body. A research team at the University of Basel, Switzerland, has uncovered how a key protein switches on the machinery that enables Leptospira pathogens to survive and cause disease.

28 Apr 2026

Innovative Device Enables Rapid Measurement of Cell Stiffness

Researchers from Brown University and their collaborators have developed a new way to measure the properties of cells - an important development, they say, because accurate measurements of changes in cell elasticity can be used to better understand diseases, diagnose patient symptoms and provide more accurate prognoses.

28 Apr 2026