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Researchers Capture the Most Detailed Images of Molecules in Chromatin Condensates

A team of researchers led by HHMI Investigator Michael Rosen has captured the most detailed images yet of the molecules in chromatin condensates — droplet-like structures of compacted DNA.

5 Dec 2025

Senescent Fibroblasts in the Tumor Niche Rewire Lung Cancer Metabolism and Plasticity

Senescent fibroblasts are aging cells that no longer divide and protect against tumor development. Yet two decades have gone by since cell biologist Judith Campisi, PhD, paradoxically demonstrated that these same cells can promote cancer growth in a laboratory setting.

5 Dec 2025

PLAMseq Revolutionizes Simultaneous Analysis of Genome Proteins and Their Locations

A team from the Andalusian Centre for Molecular Biology and Regenerative Medicine (CABIMER) has developed an innovative technique called PLAMseq (proximity-labelled affinity-purified mass spectrometry plus sequencing) that, for the first time, allows simultaneous analysis of chromatin-associated proteins and their location in the genome in a single experiment.

5 Dec 2025

New Microscopy Reveals How Cells Actively Capture the Flu Virus

Researchers at ETH Zurich have achieved an unprecedented live, high-resolution visualization of influenza virus infection within living cells.

5 Dec 2025

Nearly 1/3 of Pesticides and Industrial Chemicals Harm Gut Bacteria

A study reveals that common pesticides and industrial chemicals inhibit gut bacteria, highlighting risks to health and the need for revised safety assessments.

5 Dec 2025

Cells Use Condensates to Save RNA Messages During Stress

All cells need to sense and respond to their environment, to know when to activate genes, build proteins, and carry out their basic functions.

4 Dec 2025

New Tool Predicts Which Intrinsically Disordered Regions Drive Condensate Formation

Fusion oncoproteins arise when a gene fuses with another gene and acquires new abilities. Such abilities can include the formation of biomolecular condensates, "droplets" of concentrated proteins, DNA or RNA.

4 Dec 2025

Circular Single-Stranded DNA Molecule Can Simultaneously Silence Multiple MicroRNAs

Professor Dongsheng Liu of Tsinghua University, Professor Ziyang Hao of Capital Medical University, and Researcher Yuanchen Dong of the Institute of Chemistry, Chinese Academy of Sciences, have collaborated to develop a circular single-stranded DNA molecule capable of simultaneously silencing multiple miRNAs.

4 Dec 2025

Benchmarking DNA Language Models for Precision Genomics

Researchers at The University of Texas MD Anderson Cancer Center have performed a comprehensive evaluation of five artificial intelligence (AI) models trained on genomic sequences, known as DNA foundation language models.

4 Dec 2025

Epigenetic Signatures Explain How Andean Highlanders Thrive in Low Oxygen

DNA sequencing technology makes it possible to explore the genome to learn how humans adapted to live in a wide range of environments.

4 Dec 2025

Study Uncovers Principles Guiding Replication Initiation Across the Human Genome

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular aging, cancer, and genetic disorders.

4 Dec 2025

Study Reveals How Cells Compensate for Missing Chromosomes

A hallmark of cancerous cells is an abnormal number of chromosomes or chromosome arms, known as aneuploidy.

4 Dec 2025

New Comprehensive Atlas Transforms Understanding of Neutrophil Diversity

Neutrophils are the most abundant immune cells in the body and the first to respond to infection or tissue damage.

4 Dec 2025

New Evidence Shows Complex Life Began Far Earlier Than Previously Believed

Complex life began to develop earlier, and over a longer span of time, than previously believed, a groundbreaking new study has revealed.

4 Dec 2025

Single-Cell RNA Imaging Uncovers Four Distinct Neuron Bands in the Hippocampus

Researchers at the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC have identified a previously unknown pattern of organization in one of the brain's most important areas for learning and memory.

4 Dec 2025

Study Exposes Ancestry Biases in Current Gene Annotations

Human gene maps contain major blind spots because they were built largely from the DNA sequences of people with European ancestry, according to a study published today in Nature Communications.

4 Dec 2025

Engineered Gut Bacteria With MiRNA Nanoparticles To Reverse IBD

Biomimetic nanoparticles delivering microRNA to gut bacteria enhance protective metabolites, repair intestinal barriers, and alleviate colitis symptoms.

3 Dec 2025

Rentschler Biopharma and Coriolis Pharma Announce Strategic Collaboration for Integrated Biopharma Solutions

Rentschler Biopharma, a leading global contract development and manufacturing organization (CDMO) for biopharmaceuticals, and Coriolis Pharma, a globally operating contract research and development organization (CRDO) and a leader in formulation research and development for biopharmaceuticals, today announced a strategic collaboration.

2 Dec 2025

Light-Activated AR3 Triggers Alkalinity-Driven Apoptosis in Cancer Cells

One of the hallmarks of cancer cells is their ability to evade apoptosis, or programmed cell death, through changes in protein expression.

2 Dec 2025

Harnessing Triploid Loquat to Unlock Aneuploid Diversity for Advanced Breeding

Triploid plants are widely valued in horticulture for desirable traits such as seedlessness, yield improvement, and stress resilience.

2 Dec 2025

Life Science News

Researchers Capture the Most Detailed Images of Molecules in Chromatin Condensates

Senescent Fibroblasts in the Tumor Niche Rewire Lung Cancer Metabolism and Plasticity

PLAMseq Revolutionizes Simultaneous Analysis of Genome Proteins and Their Locations

New Microscopy Reveals How Cells Actively Capture the Flu Virus

Nearly 1/3 of Pesticides and Industrial Chemicals Harm Gut Bacteria

Cells Use Condensates to Save RNA Messages During Stress

New Tool Predicts Which Intrinsically Disordered Regions Drive Condensate Formation

Circular Single-Stranded DNA Molecule Can Simultaneously Silence Multiple MicroRNAs

Benchmarking DNA Language Models for Precision Genomics

Epigenetic Signatures Explain How Andean Highlanders Thrive in Low Oxygen

Study Uncovers Principles Guiding Replication Initiation Across the Human Genome

Study Reveals How Cells Compensate for Missing Chromosomes

New Comprehensive Atlas Transforms Understanding of Neutrophil Diversity

New Evidence Shows Complex Life Began Far Earlier Than Previously Believed

Single-Cell RNA Imaging Uncovers Four Distinct Neuron Bands in the Hippocampus

Study Exposes Ancestry Biases in Current Gene Annotations

Engineered Gut Bacteria With MiRNA Nanoparticles To Reverse IBD

Rentschler Biopharma and Coriolis Pharma Announce Strategic Collaboration for Integrated Biopharma Solutions

Light-Activated AR3 Triggers Alkalinity-Driven Apoptosis in Cancer Cells

Harnessing Triploid Loquat to Unlock Aneuploid Diversity for Advanced Breeding

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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