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Tick-Borne Parasite Treatment Benefits From Replacing Infected Red Cells

In a multicenter study, researchers at Mass General Brigham found that exchange transfusion was associated with markedly improved outcomes compared with standard treatment for a potentially life-threatening tick-borne infection

31 Mar 2026

Advanced Testing Methods Uncover Previously Hidden Bacterial Genetic Variants

Scientists at Houston Methodist Research Institute have discovered that a fast‑rising strep bacterium comes in more forms than expected, including ones that may lead to life-threatening infections.

31 Mar 2026

Novel Immunotherapy Disrupts the Protective Tumor Microenvironment Ecosystem

Chimeric antigen receptor T-cell therapy - CAR T for short - has been a major advance in treating blood cancers like leukemia and lymphoma. But the immunotherapy has struggled against solid tumors for two main reasons: tumor cells often don't share one consistent surface target, and many solid tumors are protected by a dense network of scar tissue and immune-suppressive cells that blocks T cells.

31 Mar 2026

Sweat Peptide Dermcidin Prevents Flu Virus Entry Into Cells

A research team led by the Fisabio Foundation has demonstrated that dermcidin, an antimicrobial peptide produced constitutively by the human body, also exhibits antiviral activity against the influenza virus. The study also shows that people who do not develop flu-like symptoms have higher baseline levels of this molecule, which could be associated with lower susceptibility to infection.

31 Mar 2026

Study Highlights the Vast Untapped Potential Within the Global Protein Universe

The number of known proteins is infinitely small in comparison to the universe of possible proteins which could in theory be realized. Yet these known proteins are the only major training ground for future protein design. Understanding how representative these proteins are of the overall potential diversity can therefore help inform strategies for a wide range of applications, including therapeutic, biocatalysis, or biomaterials development.

31 Mar 2026

Autism-Associated Genes are Largely the Same Across Different Global Ancestries

A new study, co-led by researchers at the Icahn School of Medicine at Mount Sinai and published March 30 in Nature Medicine, demonstrates that genes associated with autism risk are largely the same across people of different ancestries.

31 Mar 2026

New Computational Tools Improve Gene Function Determination Within Fungal Organisms

While RNA sequencing (RNA-seq) has become a standard tool for profiling which genes are active in an organism, determining the actual biological functions of those genes in fungi remains a significant technical challenge. Most existing software tools are designed to cover a broad range of species, often lacking the specificity required for the unique genetic landscape of fungi.

31 Mar 2026

New Genetic Pathways and Compounds Identified to Prevent Cone Degeneration

Scientists led by Botond Roska at the Institute of Molecular and Clinical Ophthalmology Basel (IOB) and collaborators have identified genetic pathways and compounds capable of protecting cone photoreceptors from the degeneration that underlies conditions like age-related macular degeneration.

30 Mar 2026

Identifying the Cellular Origin of MS-Related Neuroinflammation

Signals from the gut have been linked to autoimmune inflammation, but fundamental cellular processes remain poorly understood.

30 Mar 2026

New Technology Enables Whole-Body Analysis of Gene Expression

Understanding gene expression within the body has been a boon for 21st century biology and therapeutics, but most discoveries that use these technologies only focus on one organ or one small area of tissue.

30 Mar 2026

Study Explains How LACTIN-V Reduces Recurrent Bacterial Vaginosis

A new study from the Kwon Lab at the Ragon Institute, published in Cell Host & Microbe, provides the most detailed picture yet of how a promising bacterial therapy works to prevent recurrent bacterial vaginosis (BV) and why it works better for some women than others.

30 Mar 2026

New Neural Organoid System Enables Scalable Brain Network Studies

Neural organoids have been heralded as having huge potential for advancing our knowledge of the brain in several fields.

30 Mar 2026

Implantable Cell Factory Device Delivers Sustained Biologic Drug Production

Implanting living cells as long-term drug producers could transform treatment for numerous diseases, but it is difficult to house the tiny workers in quantities high enough to ensure dosage needs are met while also keeping the cells alive and thriving.

28 Mar 2026

New Platform Models Cancer Metastasis and Cell Cluster Survival

Metastasis, the spread of cancer from a primary tumor to other parts of the body, is difficult to study in the lab, in part because researchers lack reliable ways to recreate the conditions cancer cells encounter as they travel through the bloodstream.

28 Mar 2026

Genetic Study Reveals Insecticide Resistance in Malaria Vector Mosquitoes

Anopheles darlingi mosquitoes-a major vector of malaria in South America-are evolving in response to insecticides, which may make them harder to kill and malaria more difficult to control, according to a new study led by Harvard T.H. Chan School of Public Health.

28 Mar 2026

Biodegradable Plastic Byproducts Impair Fetal Growth in Mouse Study

When the "eco-friendly" bioplastic, polylactic acid (PLA), biodegrades, the resulting nanoplastics can accumulate in the fetuses of pregnant mice and interfere with fetal growth. Yichao Huang and De-Xiang Xu of Anhui Medical University, China, and Mingliang Fang of Fudan University, China, report these findings in a new study published March 26th in the open-access journal PLOS Biology.

28 Mar 2026

Global Experiment Tracks Real-Time Plant Evolution in Changing Climates

For decades, ever since biologists recognized the potential environmental harms from climate change, they have worried that plants will not be able to evolve fast enough to adapt to a rapidly warming planet.

28 Mar 2026

Computational Chemistry Maps Spliceosome Dynamics at Atomic Resolution

A new study from the Italian Institute of Technology (IIT), in collaboration with Uppsala University (Sweden) and AstraZeneca, shows how computational chemistry and supercomputers can help scientists better understand the fundamental mechanisms of life, specifically those of human cells.

28 Mar 2026

Genome-Wide Screen Reveals Drivers of Ciprofloxacin Tolerance Mechanisms

Persisters are a bacterial subpopulation that exhibits tolerance to antibiotics and plays a critical role in chronic and recurrent infections.

28 Mar 2026

Fusion Protein Rewires Brain Development to Trigger Pediatric Cancer

A team of researchers at Baylor College of Medicine, St. Jude Children's Research Hospital, Texas Children's Hospital and collaborating institutions reveal in the journal Nature a novel mechanism that drives the development of pediatric supratentorial ependymoma (EPN), the third most common pediatric brain tumor.

28 Mar 2026