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New Model Explains How Genetic Information Maintains Cellular Order

A Moffitt Cancer Center researcher has introduced a new model that addresses one of biology's most fundamental questions: How does genetic information keep living systems organized and therefore alive?

5 May 2026

Engineered Bacteriophage Speeds up the "Training" of Plastic-Eating Bacteria

Millions of tons of plastic waste build up in landfills and oceans each year. One promising approach is to engineer microbes to break plastic down into useful chemical building blocks.

4 May 2026

MRM Health’s Lead Candidate MH002 Granted Fast Track Designation by U.S. FDA for the Treatment of Mild-to-Moderate Ulcerative Colitis

MRM Health, a clinical-stage biopharmaceutical company developing therapeutics for immune-mediated diseases, which unlock the power of the microbiome to restore immune balance, today announced that MH002, the Company’s lead rationally designed Live Biotherapeutic Product (LBP) candidate, has been granted Fast Track designation by the U.S. Food and Drug Administration (FDA) for the treatment of mild-to-moderate ulcerative colitis (UC).

From MRM Health NV 4 May 2026

Genomic Tool TRACS Improves Tracking of Microbial Transmission Patterns

The research, published today (24 April) in Nature Microbiology, describes how the new tool, called TRAnsmision Clustering of Strains (TRACS), uses genomics to distinguish between closely related bacterial strains.

4 May 2026

Host Genetics and Sex Shape Evolution of Viral Virulence

During the early stages of a pandemic, viruses tend to evolve in ways that enhance their ability to reproduce and spread, rather than to evade the host's immune system.

4 May 2026

Building a Large-Scale Atlas of Female Reproductive System Aging

Despite affecting half of the world's population, menopause has historically been understudied and misunderstood, both in biomedical research and clinical practice.

30 Apr 2026

Cells Use a Timing Mechanism to Filter Persistent Physical Forces

Scientists have discovered how cells decide when to respond to physical forces, potentially opening new avenues for tackling diseases such as cancer and fibrosis.

30 Apr 2026

Visualizing Immune Synapses in Three Dimensions Using Cryo-Expansion Microscopy

Cytotoxic T lymphocytes are the body's specialized "killer" cells, precisely eliminating infected or cancerous cells.

30 Apr 2026

Accelerating Enzyme Discovery With the SMART Single-Molecule Screening System

Enzymes are proteins that catalyze chemical reactions in living organisms. They are widely applied in industries such as food production, detergents, pharmaceuticals, and chemicals.

30 Apr 2026

Pronuclei Size Competition Maintains Gene Regulation in Early Embryos

The sperm and the egg cell's nuclei compete for size directly after fertilization and this is necessary for the proper embryonic development.

30 Apr 2026

AI Reveals Dynamic DNA Accessibility Within Nucleosome Structures

Every cell in the human body squeezes over six feet of DNA into a miniscule speck invisible to the naked eye-like compressing a whole house into a single sugar cube.

30 Apr 2026

Stage-Dependent Gene Expression Changes Reveal Cellular Aging Dynamics

A new research paper was published in Volume 18 of Aging-US on April 10, 2026, titled "Stage-dependent transcriptomic changes in human dermal fibroblast senescence model."

30 Apr 2026

Prime Assembly Approach Transforms Gene Therapy With Large DNA Inserts

New technology enables the insertion of a large segment of DNA into a genome, potentially expanding gene therapy treatment from cancellation of disease-causing mutations to replacement of an entire gene, scientists say.

30 Apr 2026

Microbead Lasers Reveal Cellular Forces in Complex Tissue Environments

Researchers have developed tiny flexible lasers that can be used to measure forces inside living cells.

30 Apr 2026

Force-Sensing Microgripper Enables Safe Handling of Cell Spheroids

In tissue engineering, the tiniest bit of improper force can harm a living culture. 3D clumps of cells - known as spheroids - can be used to model complex human tissues, because they can re-create specific cell-to-cell and cell-to-matrix interactions.

30 Apr 2026

Long Read Sequencing Uncovers Telomere Length Variation Across Chromosomes

In a new proof-of-concept study published in Nature Communications, researchers at the University of Chicago analyzed genomic data from more than 2,500 participants in the national All of Us research program to estimate chromosome-specific telomere length (csTL).

30 Apr 2026

Understanding the Origin of Early Life and Mystery of Protein Folding

How did the earliest life on Earth build complex biological machinery with so few tools? A new study explores how the simplest building blocks of proteins - once limited to just half of today's amino acids - could still form the sophisticated structures life depends on.

30 Apr 2026

Extreme Hot-Wet Weather Drove Record CO₂ Surge In 2024

The 2024 surge in atmospheric CO₂ is linked to intensified ecosystem respiration, highlighting the impact of compound climatic conditions on carbon dynamics.

30 Apr 2026

How the Microbiome Shapes Cancer Immunity and Therapy Response

This review examines how the human microbiome regulates anti-tumor immunity through DNA damage, inflammation, immune-cell activity, microbial metabolites, and tumor microenvironment remodeling. It highlights emerging microbiome-based strategies, including FMT, probiotics, prebiotics, engineered bacteria, and live biotherapeutics, while stressing the need for rigorous validation and clinical trials.

29 Apr 2026

New Pipeline Sharpens Single-Cell Profiling of CAR Immune Therapies

CERTOMICS is a Nextflow-based computational pipeline designed to identify and profile CAR-engineered immune cells using single-cell multiomics data. By integrating gene expression, immune receptor profiling, protein markers, CAR-aware references, and CAR-specific quality control, it supports more standardized analysis of adoptive cellular immunotherapies.

29 Apr 2026