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Rethinking Model Organisms to Harness Nature’s Untapped Diversity

Recent epic leaps in genetics have created a biodiversity library. As the genetic make-up of animals, plants, fungi, bacteria, and viruses has been mapped, researchers racing to develop solutions to today's global challenges run into a question: Why be limited to a mouse?

12 Nov 2025

CellWhisperer Enables Natural Language Exploration of Single-Cell Biology

Using sophisticated RNA sequencing technology, biomedical researchers can measure the activity of our genes across millions of single cells, creating detailed maps of tissues, organs, and diseases.

12 Nov 2025

Global Constraint Principle Offers Fresh Insight into Life’s Growth Limits

A research team including a scientist of Earth-Life Science Institute (ELSI) at Institute of Science Tokyo, Japan, has identified a novel principle in biology that mathematically explains why the growth of organisms slows as nutrients become more abundant-a phenomenon known as "the law of diminishing returns."

12 Nov 2025

Deciphering PARP14's Role in Viral Pathogenesis

Researchers at the University of Kansas have identified that the human gene encoding the protein PARP14 plays a crucial role in regulating interferon, a key component of the body’s innate immune system.

12 Nov 2025

‘Forever chemicals’ build up in British Columbia sea otters

PFAS contamination in British Columbia sea otters underscores urban pollution's effects on marine life and the importance of long-term ecological monitoring.

12 Nov 2025

Pitt-Led Team Creates Fully Synthetic Bacteriophages, Speeding Up Discovery

A team led by University of Pittsburgh's Graham Hatfull has developed a method to construct bacteriophages with entirely synthetic genetic material, allowing researchers to add and subtract genes at will. The findings open the field to new pathways for understanding how these bacteria-killing viruses work, and for potential therapy of bacterial infections.

11 Nov 2025

Inter-Organelle Crosstalk Regulates Protein Biogenesis in Eukaryotic Cells

Janelia researchers have uncovered a novel way that two of the structures inside cells-the endoplasmic reticulum (ER) and lysosomes-coordinate the production of proteins, highlighting how interactions between organelles are important for regulating cellular processes.

11 Nov 2025

Uncovering the Mechanism of Chromosome Congression for Targeted Cancer Therapy

A research team from The University of Osaka, in collaboration with the Massachusetts Institute of Technology, has uncovered a new molecular mechanism underlying chromosome alignment during cell division.

11 Nov 2025

Study Exposes Critical Security Flaws in Widely Used DNA Sequencing Tech

Portable genetic sequencers used around the world to sequence DNA have critical, previously unreported security vulnerabilities that could reveal or alter genetic information without detection, according to a new study.

11 Nov 2025

Neanderthal DNA Reveals Secrets of Jaw Development

Every human face is unique, allowing us to distinguish between individuals. We know little about how facial features are encoded in our DNA, but we may be able to learn more about how our faces develop by looking at our ancient relatives, the Neanderthals.

11 Nov 2025

Bacterial Scents Behind Oak Tree Decline May Be Luring Deadly Beetles, Scientists Warn

The deadly decline of Britain’s native oak trees may be driven by an unexpected accomplice: their own smell.

11 Nov 2025

New Persimmon Genome Assembly Sheds Light on Early Flowering Ability

The genus Diospyros includes over 500 species, among which cultivated persimmon (D. kaki) holds great nutritional and economic importance.

10 Nov 2025

Dual Role of SlNOR and SlNOR-like1 Revealed in Tomato Pollen Development

Successful fertilization in flowering plants depends on healthy pollen development and structural integrity of the pollen wall.

10 Nov 2025

New Genetic Pathway Explains Why Some Citrus Fruits Taste Less Sour

The characteristic sour-sweet balance of citrus fruits is largely defined by citric acid accumulation in the vacuoles of juice sacs.

10 Nov 2025

Scientists Build a Genetic Map to Predict Bacterial Resistance Mechanisms

The bacteria Acinetobacter baumannii (A. baumannii) is a haunting presence in many hospitals in the United States, where more than one in 100 patients are treated for A. baumannii infections.

10 Nov 2025

Human Pangenome Research Opens a New Chapter in Precision Medicine

In May 2023, the Human Pangenome Reference Consortium (HPRC) released the first draft of the human pangenome reference sequence, which integrated genomic data from 47 individuals representing genetic diversity and added 119 million base pairs of euchromatic polymorphic sequences.

10 Nov 2025

Researchers Find "Hidden" Mutations by Tracing Protein Isoforms

Approximately 25 million individuals in the United States are affected by a rare genetic disorder, and a significant number of them face challenges not only due to the absence of effective treatments but also because of insufficient information regarding their condition.

10 Nov 2025