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New genetic condition that raises vulnerability to opportunistic infections

An international consortium co-led by Vanderbilt University Medical Center immunogeneticist Rubén Martínez-Barricarte, PhD, has discovered a new genetic disorder that causes immunodeficiency and profound susceptibility to opportunistic infections including life-threatening fungal pneumonia.

24 Jan 2023

New computational tool for long-read RNA sequencing

An evolving RNA molecule can be cut and joined, or spliced, in various ways on the path from gene to protein before being translated into a protein. Using a technique called alternative splicing, multiple proteins can be encoded by a single gene.

24 Jan 2023

Native genome model of a “live” virus replicated

An Aston University scientist has developed the world’s first computer reconstruction of a virus, complete with its native genome.

24 Jan 2023

Digital microbe database unlocks patient response to treatment

Scientists at the University of Galway, in collaboration with APC Microbiome Ireland, a world-class SFI Research Centre, have developed a database of over 7,000 digital microbes, allowing computer simulations of how drug treatments operate and how patients may respond.

24 Jan 2023

Island populations may be a lot tougher and more complex than previously thought

It's often assumed that island plant and animal populations are just the simple, fragile cousins of those on the mainland. But now, researchers from Japan have discovered that island populations may be a lot tougher and more complex than previously thought.

23 Jan 2023

Ubiquigent collaborates with University of Glasgow on translational structural biology to accelerate drug discovery within the (de)ubiquitylation field

Ubiquigent Limited (Ubiquigent), a drug discovery and development company harnessing novel deubiquitinase (DUB) modulators as new therapeutics for areas of high unmet medical need, today announced it is supporting a Master’s student at the University of Glasgow (UoG) to undertake a research project on USP30, a DUB implicated in neurodegenerative, renal, and cardiovascular diseases.

From Ubiquigent Limited 23 Jan 2023

Research reveals the genes that likely allowed whales to grow into giant sizes

New research reveals the genes that likely allowed whales to grow to giant sizes compared to their ancestors, reports a study published in Scientific Reports.

20 Jan 2023

Study reveals how complex carbon and nutrient sources are metabolized by interacting microbes

Interactions among microorganisms in soil lead to the release of nutrients derived from complex organic matter in that soil.

20 Jan 2023

Environmental DNA analysis of microbial communities can help trace a region's water cycle

Environmental DNA analysis of microbial communities can help us understand how a particular region's water cycle works.

20 Jan 2023

Discovery of the gene responsible for rare childhood cancer

The first thorough genetic map of sarcomas, created by research led by Omico, the Garvan Institute of Medical Research, and UNSW Sydney, has revealed several genes that contribute to a rare childhood cancer.

20 Jan 2023

How do methanogens grow on toxic sulfite?

Methanogens are microbes that produce methane when there is little or no oxygen in their surroundings.

From The Max Planck Institute 20 Jan 2023

Tumor progression after immunotherapy: Molecular pathways revealed

The University of Michigan’s Rogel Cancer Center researchers discovered a mechanism that explains why a subset of patients’ tumors grows rather than shrink when treated with immunotherapy.

20 Jan 2023

Bees may be exposed to glyphosate residues in the environment

Bees may be at risk from exposure to glyphosate – an active ingredient in some of the EU's most commonly used weedkillers – via contaminated wildflower nectar, according to new research from Trinity and DCU scientists.

19 Jan 2023

New center to assist in understanding non-coding cancer genome

The MacMillan Center for the Study of the Non-Coding Cancer Genome (MCSNCG) was officially launched by the New York Genome Center (NYGC) on January 18th, 2023.

19 Jan 2023

Utilizing "cyborg cells" in environment protection and medicine

At the University of California, Davis, biomedical engineers have developed “cyborg cells” that are partially alive.

From The University of California, Davis 19 Jan 2023

Benefits of Finnish health research environment for genomic research

New findings from the FinnGen study illustrate the clear advantages of the Finnish health research environment for genomic research.

19 Jan 2023

Molecular mechanism behind microtubule dynamics in R. contractilis

Raphidocystis contractilis belongs to Heliozoa, a group of eukaryotes that is generally seen in brackish, fresh, and seawater.

19 Jan 2023

Blending multiple maps uncover new genetic causes of blindness

In a new study, Ran Elkon and Ruth Ashery-Padan of Tel Aviv University, Israel, and colleagues discovered a new genetic risk factor for adult-onset macular degeneration (AMD) by combining a map of gene regulatory sites with disease-associated loci.

18 Jan 2023

Potential to rectify various disease-causing mutations enhanced by CRISPR-based enzymes

Designing genome editing strategies for each patient’s mutation would be impractical and expensive because many genetic diseases are induced by diverse mutations spread across an entire gene.

18 Jan 2023

New revelations on the immune system’s defenses against infections

Cells competing for a place in a germinal center confront a tough admissions process. Germinal centers, which form following exposure to a pathogen or vaccine, serve as a kind of immune system training academy, assisting B cells in refining their response to the threat.

18 Jan 2023