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New Study Reveals Antibiotic Mismanagement in Aged Care Facilities

There is an urgent need for more careful antibiotic management to protect older people living in residential aged care from the dangerous spread of antibiotic-resistant bacteria or 'superbugs', researchers from Flinders University and SAHMRI warn.

29 Aug 2024

The Influence of 'Silent' Mutations on Genetic Disorders

Genetic disorders -; like cystic fibrosis and Huntington's disease -; are considered incurable, with gene mutations occurring in essentially every cell of the body.

29 Aug 2024

Nutrient Deprivation Strategy Kills Breast Cancer Cells by Blocking Adaptive Pathways

Cancer cells have voracious appetites. And there are certain nutrients they can't live without. Scientists have long hoped they might stop tumors in their tracks by cutting off an essential part of cancer cells' diet. But these cells are crafty and often find a new way to get what they need. How? By reprogramming their metabolism and switching to backup food supplies.

29 Aug 2024

New Map Reveals Hidden Interactions Between Receptors and Proteins

A single superfamily of receptors found on the surface of human cells is the target of one out of every three FDA-approved medications.

28 Aug 2024

Clock Genes Drive Evolutionary Split in Two Moth Species

Investigating moth speciation, this research highlights the impact of clock genes on behavior, providing a rare glimpse into evolutionary processes.

28 Aug 2024

Stem Cell Research Sheds Light on Rare Pediatric Condition

Scientists have identified mutations in the DENND5A gene that cause severe neurodevelopmental issues in infants, leading to improper brain cell division during development.

28 Aug 2024

RNA Interference Drugs Offer Faster, More Effective Alternative to Traditional Drug Discovery

Alnylam's RNA interference platform accelerates drug discovery by targeting RNA transcripts, addressing complex diseases with innovative therapeutic strategies.

28 Aug 2024

Cryo-EM Study Sheds Light on HSV Drug Resistance Mechanisms Through Protein Movement

All organisms -; from fungi to mammals -; have the capacity to evolve and adapt to their environments. But viruses are master shapeshifters with an ability to mutate greater than any other organism. As a result, they can evade treatments or acquire resistance to once-effective antiviral medications.

28 Aug 2024

CDCA7's Role in DNA Methylation Maintenance Revealed in Recent Study

DNA methylation is a process in which a methyl group is attached to the cytosine base of the DNA molecule, and a major way that DNA is epigenetically marked. Epigenetic modifications can act as on-off switches to regulate gene expression and help generate diverse cell types without changing the underlying DNA sequence. It is how the body ensures that brain-related genes don't get turned on in heart cells, for example.

28 Aug 2024

Pesticide Exposure Strongly Correlated with Fewer Wild Bee Sightings

Whether you're strolling through a garden, wandering a park, or simply enjoying an open space in the United States, you're likely to notice bees buzzing about the flowers. While honeybees, imported from Europe in the 17th century to produce honey, are the most recognizable, they aren't the only bees at work. If you're a keen observer, you might spot some of the thousands of less familiar, native bee species that call these spaces home.

28 Aug 2024

EMBL Researchers Develop Novel Photoacoustic Probes to Monitor Brain Activity

To understand the brain better, we need new methods to observe its activity.

28 Aug 2024

High-Resolution Structures Illuminate the Chloroplast Protein Import Machinery in Plants

Two groundbreaking studies published in the journal Cell shed light on the assembly, function and evolutionary diversity of the chloroplast protein import system.

28 Aug 2024

NIR Spectroscopy Offers a New Frontier in Crop Analysis

In the agricultural and food industry, determining the chemical composition of raw materials is important for production efficiency, application, and price. Traditional laboratory testing is time-consuming, complicated, and expensive. New research from the University of Illinois Urbana-Champaign demonstrates that near-infrared (NIR) spectroscopy and machine learning can provide quick, accurate, and cost-effective product analysis.

28 Aug 2024

Unraveling the Molecular Mechanism Behind Neocapritermes taracua's Explosive Defense

Researchers from the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, in cooperation with colleagues from the Faculty of Tropical AgriScience of the Czech University of Life Sciences in Prague, are unraveling the mysteries of the life of termites.

28 Aug 2024

A Breakthrough in RNA Therapy for Heart and Nervous System Diseases

Researchers at the University of California San Diego have developed new techniques to sculpt RNA molecules into circles that may result in more potent and long-lasting treatments.

27 Aug 2024

Gut Microbiota Modulates Rotavirus Vaccine Effectiveness

Scientists at Georgia State University's Institute for Biomedical Sciences have shown that some gut flora can reduce the effectiveness of the rotavirus vaccine.

27 Aug 2024

Innovative Stem Cell Research Unveils Glial Cell Dynamics in Multiple Sclerosis

Researchers from The New York Stem Cell Foundation (NYSCF) Research Institute and Case Western Reserve University have discovered novel ways in which glia, by using the largest known collection of stem cell models from MS patients, essential brain support cells contribute to the disease.

27 Aug 2024