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Rhizosphere Metabolites Play Key Role in Regulating the Distribution of Antibiotic Resistance Genes

Their study reveals that rhizosphere metabolites-substances secreted by plant roots-play a crucial role in regulating the distribution of manure-derived ARGs in both the soil and plant tissues.

27 Oct 2025

Enhancing Ovarian Cancer Treatment with Multi-Modal Immunotherapy Approach

Results of a study led by researchers at Roswell Park Comprehensive Cancer Center show that combining two types of immunotherapy - engineered T cells that secrete bispecific T cell engagers (BiTEs) and an immune checkpoint inhibitor - can alter the tumor microenvironment to launch a stronger attack against ovarian cancer and reduce the risk of relapse.

27 Oct 2025

First Chromosome-Scale Genome Assembly of Blackcurrant Reveals Drought Adaptation Strategies

Drought stress disrupts plant growth, metabolism, and reproduction, with devastating effects on crop productivity worldwide.

27 Oct 2025

Mitochondria and Lysosomes Orchestrate Metabolic States of Regulatory T Cells

Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system.

27 Oct 2025

Simple Genetic Switch can Underlie Temperature-Mediated Plasticity in Butterfly Wing Patterns

Scientists from the National University of Singapore (NUS) have discovered a simple DNA "switch" that helps tropical butterflies adjust the size of their wing eyespots in response to seasonal temperatures, shedding light on the evolution of environmental sensitivity.

27 Oct 2025

Understanding Interplay of Physiological Processes as the Brain Shifts from Wakefulness to Sleep

Findings from Mass General Brigham investigators highlight the intricate interplay of diverse physiological processes as the brain shifts from wakefulness to sleep.

27 Oct 2025

Study Reveals How TR4 Fungus Silences Banana Defense Genes

Bananas rank among the world's most valuable staple crops, yet their production faces severe losses from Fusarium wilt caused by Fusarium oxysporum f. sp. cubense (Foc) tropical race 4 (TR4).

24 Oct 2025

RNA-Based Molecular Switch Enhances Disease Resistance in Pears

In recent years, scientists have uncovered the remarkable regulatory power of long non-coding RNAs (lncRNAs) - RNA molecules once dismissed as "genetic dark matter."

24 Oct 2025

Disrupted Circadian Rhythms Alter Gene Activity in Alzheimer’s Disease

Alzheimer's disease is notorious for scrambling patients' daily rhythms. Restless nights with little sleep and increased napping during the day are early indicators of disease onset, while sundowning, or confusion later in the day, is typical for later stages of the disease.

24 Oct 2025

Hidden RNA Inside a Gene Solves Decades-Old Telomere Mystery in Roundworms

An international research team led by Hiroki Shibuya at RIKEN Center for Biosystems Dynamics Research (BDR) in Japan has solved a genetic mystery and revealed a previously unknown way that DNA can control what cells do.

24 Oct 2025

New Retron-Based Gene Editing Method Corrects Multiple Disease-Causing Mutations

Some genetic disorders-such as cystic fibrosis, hemophilia and Tay Sachs disease-involve many mutations in a person's genome, often with enough variation that even two individuals who share the same disorder might have a different combination of mutations.

24 Oct 2025

Study Shows Flatulence Gas Hydrogen is Crucial for Gut Health

Farts are causing a stink in the research world, but in a positive way.

24 Oct 2025

GemPharmatech Teams Up With Memorial Sloan Kettering to Advance Antibody Innovation

GemPharmatech, a global leader in preclinical research solutions and genetically-engineered mouse models, today announced a collaboration with Memorial Sloan Kettering Cancer Center (MSK) to accelerate the discovery of new therapeutic antibodies.

24 Oct 2025

Breakthrough Cryo-EM Study Maps Herpes Replication Protein in New Detail

An international research team has successfully identified the initial high-resolution structures of the herpes simplex virus origin-binding protein (OBP), which is an essential element in viral DNA replication that has remained structurally uncharacterized for the past forty years.

24 Oct 2025

Scientists Reveal How Nanovaccines Boost the Immune Fight Against Aggressive Breast Cancers

Nanovaccines show promise in breast cancer therapy, enhancing immune activation and targeting cold tumors, particularly in challenging triple-negative cases.

24 Oct 2025

DNA Cassettes Enable Long-Lasting Antibody Production Directly Inside Patients

A multidisciplinary team of scientists led by The Wistar Institute, including Perelman School of Medicine at the University of Pennsylvania, AstraZeneca and Inovio Pharmaceuticals, published today in Nature Medicine a breakthrough in biologic antibody production that happens directly in human subjects in this encouraging first clinical trial of its kind.

23 Oct 2025

Life Science News

Rhizosphere Metabolites Play Key Role in Regulating the Distribution of Antibiotic Resistance Genes

Enhancing Ovarian Cancer Treatment with Multi-Modal Immunotherapy Approach

First Chromosome-Scale Genome Assembly of Blackcurrant Reveals Drought Adaptation Strategies

Mitochondria and Lysosomes Orchestrate Metabolic States of Regulatory T Cells

Simple Genetic Switch can Underlie Temperature-Mediated Plasticity in Butterfly Wing Patterns

Understanding Interplay of Physiological Processes as the Brain Shifts from Wakefulness to Sleep

Study Reveals How TR4 Fungus Silences Banana Defense Genes

RNA-Based Molecular Switch Enhances Disease Resistance in Pears

Disrupted Circadian Rhythms Alter Gene Activity in Alzheimer’s Disease

Hidden RNA Inside a Gene Solves Decades-Old Telomere Mystery in Roundworms

New Retron-Based Gene Editing Method Corrects Multiple Disease-Causing Mutations

Study Shows Flatulence Gas Hydrogen is Crucial for Gut Health

GemPharmatech Teams Up With Memorial Sloan Kettering to Advance Antibody Innovation

Breakthrough Cryo-EM Study Maps Herpes Replication Protein in New Detail

Scientists Reveal How Nanovaccines Boost the Immune Fight Against Aggressive Breast Cancers

DNA Cassettes Enable Long-Lasting Antibody Production Directly Inside Patients

Research Pinpoints HMGN1 as Cause of Trisomy 21-Related Heart Abnormalities

Hungry Female Mice Turn Aggressive Toward Pups Only in Specific Hormonal States

Biological Bulldozer Mechanism Explains Ants’ Powerful Sense of Smell

Fully Automated 3D Framework Accurately Maps Fruit Microstructure

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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