For a long time, James McKerrow, MD, PhD, dean of the Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego, has investigated neglected tropical diseases, which are chronic, disabling parasitic infections mainly affecting the poor and underserved communities in developing nations.

5 Apr 2021

Novel device can help treat type I diabetes mellitus

Type I Diabetes Mellitus, also called T1D, is an autoimmune disorder that results in an irreversible loss of insulin-producing beta-cells found in the pancreas.

2 Apr 2021

New mechanism of transcriptional regulators influences tumor development

The Wistar Institute scientists have discovered a novel mechanism of transcriptional regulation of cellular senescence that promotes the release of inflammatory molecules that, in turn, affect tumor growth by changing the surrounding microenvironment.

2 Apr 2021

New AI-based method can lead to faster, low-cost development of protein-based drugs

Thanks to a newly published study by scientists, artificial intelligence (AI) can now create novel and functionally active proteins.

1 Apr 2021

B.1.1.7 variant of SARS-CoV-2 spreading quickly in the United States

The faster-spreading B.1.1.7 variant of SARS-CoV-2 first detected in the United Kingdom, the coronavirus that causes COVID-19, is quickly on its way to becoming the dominant variant of the virus in the United States, according to a study from scientists at Scripps Research and the COVID-19 test maker Helix.

31 Mar 2021

Experimental antibody therapies for neurodegenerative diseases may lead to brain inflammation

A research team has made a novel finding that indicates that experimental antibody treatments for Alzheimer’s disease have an accidental adverse impact.

31 Mar 2021

Study shows how WAVE2 protein maintains the immune system balance

Sinai Health researchers have reported that they have uncovered a new mechanism that regulates harmful overreactions in the body’s immune system.

26 Mar 2021

Antibody used for COVID-19 therapy can no longer inhibit new SARS-CoV-2 variants

Cell culture studies show that mutated viruses are less susceptible to inhibition by antibodies from recovered or vaccinated individuals.

26 Mar 2021

Study shows SARS-CoV-2 antibodies wane at different rates

Researchers from Duke-NUS Medical School, the National Centre for Infectious Diseases (NCID), and the Agency for Science, Technology and Research (A*STAR) Infectious Diseases Labs have discovered that antibodies against SARS-CoV-2 decline at different speeds, and these antibodies last for only a few days in some people but remain for many years in other individuals.

24 Mar 2021

Specific enzyme can delay the growth and spread of neck and head carcinomas

Scientists were able to considerably delay the growth and proliferation of tumors in mice and improve the effectiveness of immunotherapy.

24 Mar 2021

Non-circulating memory T cells contribute to chronic transplant rejection

The main function of non-circulating memory T cells is to offer local protection against re-infection.

22 Mar 2021

Study identifies new biomarkers for the prognosis of gastric adenocarcinoma

A study headed by UCM reports that polymorphisms in gene TGFB1 and low plasma levels of protein TGFB1 serve as biomarkers for the gastric adenocarcinoma prognosis.

19 Mar 2021

Immune receptor proteins can help treat autoimmune diseases

TARM1 is a receptor protein, whose function in the working of the immune system is not known yet. Now, in a new research work, Japanese researchers have analyzed mouse models to investigate the promising role of TARM1 protein in the pathogenesis of rheumatoid arthritis.

18 Mar 2021

Key protein regulates cells’ innate defense mechanisms

Scientists from the University of Illinois Chicago (UIC) have found that heparanase (HPSE) is an important regulator of innate defense mechanisms of cells.

17 Mar 2021

Revealing clues about the immune system through ancient DNA

AZoLifeSciences speaks to Dr. Gaspard Kerner about tuberculosis, and how ancient DNA could help us to further understand the immune system.

12 Mar 2021

Study sheds light on how T cells specialize to combat pathogens

Scientists from the University of Basel have gained insights into the specialization of T cells.

11 Mar 2021

Spraying leaves with vitamin C can dramatically increase protein production

The production of high-value pharmaceutical proteins in plants provides benefits over other manufacturing techniques.

10 Mar 2021

Regenerating bone marrow after chemotherapy

In this interview, AZoLifeSciences speaks to Professor Masaru Ishii about his latest research that investigated how bone marrow regenerates after chemotherapy.

10 Mar 2021

Immune cells in cerebrospinal fluid could be biomarkers to predict immunotherapy response

Results from a study led by Joan Seoane, Director of Preclinical and Translational Research co-program at VHIO and ICREA Professor, show that immune cells accessing cerebrospinal fluid faithfully recapitulate the characteristics of cells identified in brain metastasis, and could therefore constitute novel biomarkers of response to immune-based therapies.

9 Mar 2021