There is still a large unmet medical need for the treatment of ulcerative colitis, despite recent improvements in the understanding of the pathogenic mechanisms of ulcerative colitis.

30 Sep 2022

Tiny DNA strand net in a low-cost test platform traps COVID-19 virus

According to a new study, tiny nets made of DNA strands can capture the spike protein of the virus that causes COVID-19, illuminating it for a quick yet accurate diagnostic test and preventing it from infecting cells, suggesting a new potential path to antiviral treatment.

26 Sep 2022

Carp virus provides significant insights into immunology

In an article published in the journal Nucleic Acids Research, the team led by Prof. Alain Vanderplasschen, a virologist and immunologist at the University of Liège, describes 10 years of research on how a carp virus uses a protein domain called Zalpha (Zα) to inhibit the host cell’s defense mechanisms.

26 Sep 2022

Novel means to prevent and treat gonorrhea

According to scientists from the Georgia State University’s Institute for Biomedical Sciences, producing a mutation that impedes the way the bacterial pathogen Neisseria gonorrhoeae transmits gonorrhea might provide a novel means to prevent and treat the disease.

26 Sep 2022

Encouraging breakthroughs in eliminating therapy-resistant cancer cells

The human immune system is notably adept at evading tumor cells, which construct physical barriers, adopt masks, and restrain the immune system with molecular ploys.

14 Sep 2022

PhoreMost enters multi-project drug target discovery collaboration with Roche

PhoreMost to deploy its SITESEEKER platform to identify novel targets for Roche’s discovery programmes

From PhoreMost 6 Sep 2022

Cell Counting Without Slides to Reduce Waste and Cost

Until recently, cells were typically counted on a reusable quartz hemocytometer. With the advent of automated cell counters 12-15 years ago, disposable slides became widespread.

From DeNovix Inc. 1 Sep 2022

Detecting multiple food poisoning bacteria based on color differences in scattered light from metals

Osaka Metropolitan University scientists have developed a simple, rapid method to simultaneously identify multiple food poisoning bacteria, based on color differences in the scattered light by nanometer-scaled organic metal nanohybrid structures (NHs) that bind via antibodies to those bacteria.

30 Aug 2022

A “stress test” with a previously unknown gene to revive the exhausted T cells

The task of battling cancer cells can fatigue T cells employed in immunotherapy treatments, or they could shut down once they penetrate tumors. Researchers at the Gladstone Institutes and UC San Francisco have strengthened the therapeutic cells’ resistance via a CRISPR-based edit on their genomes.

30 Aug 2022

Unconventional T cells migrate and influence immune responses

There are 600 to 800 lymph nodes in the human body, which are specialized organs that cause immunological reactions. Lymph nodes are connected to the various organs by lymph vessels, allowing them to receive information about infections in the body.

25 Aug 2022

Study explains the dynamics underlying liver damage

The immune system may attack the liver when fat builds up there. The chemical that triggers these responses has been discovered by Weill Cornell Medicine researchers in a recent study, and this information helps to explain the dynamics of liver damage that can accompany type 2 diabetes and obesity.

23 Aug 2022

New method identifies human gut microbes that contribute to inflammatory diseases

Researchers at Cedars-Sinai have created a way to determine the human gut microorganisms that are most likely to cause a variety of inflammatory disorders, including obesity, liver disease, inflammatory bowel disease, cancer, and several neurological conditions.

22 Aug 2022

Re-defining the limits of single batch assay stabilisation

In response to increasing demand for stabilised molecular diagnostic assays, we have significantly increased our single batch lyophilised reagent bead manufacturing throughput to 300,000 reactions per freeze drying run and are now progressing towards a capacity of 100 million tests per annum.

From Biofortuna Limited 22 Aug 2022