Antibodies and Immunology

What are Therapeutic Antibodies?

Recent years have seen therapeutic antibodies, specifically, monoclonal antibodies, grow rapidly in their use in treating a range of diseases and illnesses.

Research Developments in Monoclonal Antibodies

Antibody-Antigen Recognition- How Does it Work?

Creating a Nanobody Library with PCR

Purifying Antibodies Using Ion Exchange Chromatography

VHH Antibodies (Nanobodies) Advantages and Limitations

Latest Antibodies and Immunology News and Research

Researchers design antibody to identify pathogens of Alzheimer's disease

Researchers have found a way to design an antibody that can identify the toxic particles that destroy healthy brain cells - a potential advance in the fight against Alzheimer's disease.

26 May 2020

A 'Switch' That Turns Autoimmunity Drugs Into Powerful Anti-Cancer Treatments

Scientists have discovered a way to transform antibody drugs into antibodies with powerful anti-cancer activity through a simple molecular "switch".

22 May 2020

New flow cytometry technique to quantify protein production in T-cells

A team of scientists from Hollings Cancer Center at the Medical University of South Carolina has developed a novel flow cytometry technique that can, for the first-time, quantify protein production in T-cells.

21 May 2020

X-ray experiments reveal antibody to block entry of SARS-CoV-2

As scientists across the globe race to develop a vaccine against SARS-CoV-2, the coronavirus that causes COVID-19, an international team led by Davide Corti at Vir Biotechnology and David Veesler at the University of Washington has been working around the clock on a complementary approach - identifying neutralizing antibodies that could be used as a preventative treatment or as a post-exposure therapy.

20 May 2020

ChIP kits for high throughput antibody validation

Porvair Sciences report how its Chromatrap® ChIP kits provide an outstanding solution for antibodies suppliers looking to validate the performance of the antibodies they produce for chromatin immunoprecipitation (ChIP) assay kits.

From Porvair Sciences Limited 20 May 2020

Cross-neutralization of SARS and COVID-19 coronaviruses by an antibody

An antibody first identified in a blood sample from a patient who recovered from Severe Acute Respiratory Syndrome in 2003 inhibits related coronaviruses, including the cause of COVID-19.

19 May 2020

Study shows coronavirus does not induce cross-protective immune antibodies

According to researchers, patients infected with severe acute respiratory syndrome coronavirus (SARS-CoV) or SARS-CoV-2 generate antibodies that adhere to the other coronavirus; however, the cross-reactive antibodies are not actually cross-protective, as far as cell-culture experiments are concerned.

19 May 2020

A New Imaging Approach To See Multiple Proteins Simultaneously

Degenerative diseases such as Alzheimer's often involve complex interactions between multiple proteins and other biomolecules.

19 May 2020

The Global Hunt To Block COVID-19

A molecular biologist is working with a world leader in artificial intelligence-based drug discovery to help find a molecule that could prevent SARS-CoV-2.

19 May 2020

Study offers a benchmark for testing potential vaccines for COVID-19

Globally, researchers are racing against time to design a vaccine to guard against the COVID-19 infection, and epidemiologists are taking efforts to predict the way the coronavirus pandemic will spread until the availability of such a vaccine.

18 May 2020

Computational methods can help design protein-based vaccines

Vaccines are regarded as an effective intervention to stop the spread of infectious diseases. They produce antibodies by activating the immune system.

18 May 2020

Blood Cells Could Serve As A 'Thermometer' To Detect Breast Cancer

Immune system cells in the blood of breast cancer patients undergo alterations early in the disease course, according to a study.

18 May 2020

ChIP kits for high throughput antibody validation

From Porvair Sciences Limited 15 May 2020

Coronavirus attacking microRNA numbers reduce with age

A group of tiny RNA that should attack the virus causing COVID-19 when it tries to infect the body are diminished with age and chronic health problems, a decrease that likely helps explain why older individuals and those with preexisting medical conditions are vulnerable populations, investigators report.

14 May 2020

Researchers identify missing component of innate immune signaling

How cells recognize pathogens and alert the immune system swiftly is a fundamental process of high importance for the survival of any species, including humans.

14 May 2020

A New Plant-Based System For The Mass Production Of Allergens For Immunotherapy

Allergen immunotherapy provides long-lasting relief to people suffering from allergies, but the therapy can last years and requires large amounts of allergen.

13 May 2020

The microbiome regulates our immune system's fitness

Working alongside colleagues in Mainz, Bern, Hannover and Bonn, researchers from Charité - Universitätsmedizin Berlin, the Berlin Institute of Health and the German Rheumatism Research Center Berlin were able to show how the microbiome helps to render the immune system capable of responding to pathogens.

13 May 2020

New type of antigen-presenting immune cell discovered

With a discovery that could rewrite the immunology textbooks, an international group of scientists, including the teams of Bart Lambrecht, Martin Guilliams, Hamida Hammad, and Charlotte Scott (all from the VIB-UGent Center for Inflammation Research) identified a new type of antigen-presenting immune cell.

12 May 2020

Selectively eliminating leukemic and hematopoietic stem cells

Acute myeloid leukemia is an aggressive cancer of the blood-forming system. It affects the hematopoietic stem cells, or blood stem cells, of various white blood cells and of the red blood cells and platelets.

11 May 2020

Novel mechanism allows the immune system to control autoimmunity, cancer

Scientists at the Department of Infection and Immunity of the Luxembourg Institute of Health (LIH) revealed a novel mechanism through which the immune system can control autoimmunity and cancer.

7 May 2020