Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Single-Molecule Optical Tweezers Visualize Real-Time Dynamic Protein and DNA Interactions

A protein that's essential to every cell's ability to turn off unnecessary genes is well known for its key function of compacting genes and its connection to cancer when it undergoes mutation.

1 Oct 2026

Electron Microscopy Imaging Confirms Piezo1-Dependent Axonal Sheath Structural Remodeling

Researchers at Upstate Medical University have identified a key mechanism that helps determine the length of myelin, the protective coating that surrounds many nerve fibers and allows signals to travel efficiently through the nervous system.

1 Oct 2026

Single-Molecule Optical Tweezers Visualize Real-Time Dynamic Protein and DNA Interactions

A protein that's essential to every cell's ability to turn off unnecessary genes is well known for its key function of compacting genes and its connection to cancer when it undergoes mutation. But until now, scientists weren't quite sure how the protein gets where it needs to go to keep genes bound up so they aren't activated.

1 Oct 2026

Single-Cell Metabolic Profiling Identifies Key Bioenergetic Targets in Human Tumor Tissue

Immune cells can reach head and neck tumors, but once there, many stop functioning. This helps explain why immunotherapy with immune checkpoint inhibitors - which have transformed treatment for some cancers - benefit only 17%–23% of patients with head and neck squamous cell carcinoma. These are cancers that arise from cells lining the mouth, throat and voicebox.

1 Oct 2026

Kupffer Cells Increase Apolipoprotein Secretion in Response to Indigestible Plastics

Microplastics appear capable of significantly impairing the function of phagocytes in the liver, at least in mice. In turn, this disrupts the metabolism of this vital organ and increases the build-up of fat inside it. These are the key findings from a joint German-Austrian study led by the University of Bonn, details of which have now been published in the journal "Nature Metabolism."

1 Oct 2026

A Flash of Blue Light Helped Cells Overcome a Major Division Defect

Cell division represents a complex process. Central to this intricacy is a cellular structure devoid of a membrane, known as the centrosome, consisting of over 200 different components.

30 Sep 2026

Innovative OpenFISH Technique Enables Integrated Spatial Molecular Imaging in Tissues

Spatial transcriptomics (ST) shows which genes are being expressed and where within a tissue. Spatial metabolomics (SM), on the other hand, maps the location of metabolites—small molecules produced or used by cells—within tissue.

30 Sep 2026

Gut-Derived Neutral Ceramidase Regulates MASH Through Microbial and Epithelial Signaling

Metabolic dysfunction-associated steatohepatitis (MASH) is often viewed through the lens of hepatic lipid accumulation, inflammation and fibrosis.

30 Sep 2026

Targeted Y Chromosome Deletions Disrupt Key Cellular Immune Response Pathways

A new study found that cancer cells selectively chip away gene-rich sections of the Y chromosome, triggering ripples that regulate tumor growth.

29 Sep 2026

Study Establishes Immune Cell Trafficking as Viable Alzheimer's Target

There is no treatment available today to stop the death of brain cells in neurodegenerative diseases known as tauopathies, including Alzheimer's disease, in which twisted clumps of a protein called tau accumulate in the brain.

29 Sep 2026

Single-Cell Sequencing Confirms Epigenetic Remodeling Across Diverse Cardiac Cell Types

The adult human heart is a reliable and resilient engine fueling our everyday lives while also being responsive enough to supercharge a Usain Bolt sprint or sustain a three-week bike race in the French Alps and Pyrenees.

29 Sep 2026

Scientists Pinpoint the Brain Circuit That Regulates Metabolism

As the body’s temperature decreases, it compensates by utilizing additional energy to produce heat and stimulating the desire to eat to replenish the energy expended for warmth.

28 Sep 2026

Post-Translational Modification Crosstalk Regulates Oncogenic Protein Stability and Activity

A review published in Genes & Diseases highlights the complex interplay between protein arginine methylation and ubiquitination, two forms of protein modification that can profoundly influence cancer development, progression and treatment response. The article brings together current understanding of how these interconnected molecular processes regulate proteins involved in cancer and identifies opportunities for future therapeutic approaches.

28 Sep 2026

Engineered 3D miBrains Model Human Neurovascular Units and Pathology

Mount Sinai researchers have identified how APOE4, the strongest genetic risk factor for Alzheimer's disease, damages the brain's blood vessels and promotes the buildup of abnormal proteins linked to neurodegenerative disease.

26 Sep 2026

Researchers Engineer Synthetic Plant Receptors to Supercharge Crop Immunity

Nanyang Technological University, Singapore (NTU Singapore) scientists have developed a way to "supercharge" a plant's natural immune response.

26 Sep 2026

AI-Designed Synthetic Polymers Mimic Natural Peptides to Beat Superbug Resistance

Swimming through the blood, sweat, cells, and tears of all humans are tiny proteins referred to as peptides.

25 Sep 2026

Chronic Inflammation Linked to Heart Changes and Risks

Chronic inflammation, indicated by GlycA levels, has been linked to heart changes and increased cardiovascular risk, highlighting genetic and environmental interactions.

25 Sep 2026

Cryo-ET Reveals Native Membrane Architecture of Synchronous RyR1 Calcium Channels

Using cryo-electron microscopy, researchers at the Max Delbrück Center have revealed how muscle cell calcium channels open synchronously. The findings, published in "Nature Communications," may explain a mechanism behind serious muscle diseases.

25 Sep 2026

Engineered E. coli Strains Validate Putrescine Uptake and Systemic Host Conversion

Gut microbiota influences multiple aspects of host physiology, including metabolic and immune functions. Many metabolites produced by gut bacteria can cross the intestinal epithelium (which the bacteria may not be able to cross) and enter host tissues, providing a pathway through which microbial activity can influence host physiology.

25 Sep 2026

3D Stem-Cell miBrains Model Complex Neurovascular Pathology in Human Tissue

25 Sep 2026

Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Single-Molecule Optical Tweezers Visualize Real-Time Dynamic Protein and DNA Interactions

Electron Microscopy Imaging Confirms Piezo1-Dependent Axonal Sheath Structural Remodeling

Single-Molecule Optical Tweezers Visualize Real-Time Dynamic Protein and DNA Interactions

Single-Cell Metabolic Profiling Identifies Key Bioenergetic Targets in Human Tumor Tissue

Kupffer Cells Increase Apolipoprotein Secretion in Response to Indigestible Plastics

A Flash of Blue Light Helped Cells Overcome a Major Division Defect

Innovative OpenFISH Technique Enables Integrated Spatial Molecular Imaging in Tissues

Gut-Derived Neutral Ceramidase Regulates MASH Through Microbial and Epithelial Signaling

Targeted Y Chromosome Deletions Disrupt Key Cellular Immune Response Pathways

Study Establishes Immune Cell Trafficking as Viable Alzheimer's Target

Single-Cell Sequencing Confirms Epigenetic Remodeling Across Diverse Cardiac Cell Types

Scientists Pinpoint the Brain Circuit That Regulates Metabolism

Post-Translational Modification Crosstalk Regulates Oncogenic Protein Stability and Activity

Engineered 3D miBrains Model Human Neurovascular Units and Pathology

Researchers Engineer Synthetic Plant Receptors to Supercharge Crop Immunity

AI-Designed Synthetic Polymers Mimic Natural Peptides to Beat Superbug Resistance

Chronic Inflammation Linked to Heart Changes and Risks

Cryo-ET Reveals Native Membrane Architecture of Synchronous RyR1 Calcium Channels

Engineered E. coli Strains Validate Putrescine Uptake and Systemic Host Conversion

3D Stem-Cell miBrains Model Complex Neurovascular Pathology in Human Tissue

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Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Omics eBook

The Future of Vision Restoration With ReVision Implant

How a Single List Is Changing Visibility for Women in Science

How Avatar Medical's 3D Technology Is Transforming How We Visualize the Human Body

RecentIndustryFocuses

Editorial Focus eBook - Biopharmaceuticals (2nd edition)

Improving Cell Culture Efficiency with Image-Guided Automation

Improving Scalability in Organoid Research

Cosmetic Formulation and Manufacturing

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