Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

New Method Reveals How Tumors Rewire Genetic Splicing Programs

Cancer is caused by faulty genes, but what also shapes a cancer cell's behaviour is how a gene's instructions are trimmed and rearranged before they are turned into the proteins that keep a cell alive.

13 Mar 2026

Comprehensive Brain Atlas Maps Epigenetic Changes During Aging

Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to Parkinson's to ALS and beyond, is expected to double every 20 years.

13 Mar 2026

Dual Mechanism of Deep-Sea Sponge Compound Suppresses Cancer Cell Proliferation

A collaborative research team led by Professor Kaori Sakurai at Tokyo University of Agriculture and Technology, together with Associate Professor Hiroaki Itoh and Professor Masayuki Inoue at Graduate School of Pharmaceutical Sciences, the University of Tokyo, has uncovered a previously unknown mechanism of action of yaku'amide B, a structurally complex peptidic natural product derived from deep-sea sponge found in the waters near Yakushima Island, Japan.

12 Mar 2026

Study Reveals How Altering Cancer’s Protein Machinery Stimulates Antitumor Immunity

A new study led by Pierre Close's team (GIGA, Laboratory of Cancer Signaling, and WELRI Investigator) reveals how subtly disrupting the way tumors produce their proteins can trigger a potent antitumor immune response.

12 Mar 2026

Gut Microbes Reshape Ovarian Aging in Mice

Findings indicate gut microbes impact ovarian function in mice, offering insights into reproductive aging and potential microbiome-based health interventions.

12 Mar 2026

Scientists Map Protein Landscape Driving Photosynthesis in Plant Cells

Research led by scientists at Washington State University has revealed insights on how plants form a microscopic landscape of proteins crucial to photosynthesis, the basis of Earth's food and energy chain.

11 Mar 2026

Computational Tool Improves Detection of Microbes in Tumor Sequencing Data

When scientists sequence tumor DNA, they typically find small amounts of genetic code from bacteria, viruses and fungi – microorganisms that, if actually present in tumor tissues, could influence how they grow, evade immunity or respond to treatment.

11 Mar 2026

How SARS-CoV-2 Hijacks Host tRNA Chemistry to Sustain Infection

Findings reveal coronaviruses exploit stress-linked tRNA modifications, enhancing translation efficiency and offering insights for antiviral drug development.

11 Mar 2026

Whole-Cell Simulation Recreates Molecular Dynamics of Minimal Living Cell

By simulating the life cycle of a minimal bacterial cell - from DNA replication to protein translation to metabolism and cell division - scientists have opened a new frontier of computer vision into the essential processes of life.

10 Mar 2026

Setd8 Enzyme Preserves Retinal Progenitor Identity During Eye Development

The retina is a thin layer of neural tissue at the back of the eye that detects light and converts it into signals, sent to the brain.

10 Mar 2026

Optovolution Uses Light to Guide the Evolution of Dynamic Proteins

Evolution is biology's powerful method of engineering. It works by generating many variants of DNA, RNA, and proteins inside cells and letting nature "select" the organism that performs best.

9 Mar 2026

Discovery of Nuclear Metabolic Fingerprints Offers New Insights Into Cancer

More than two hundred metabolic enzymes, many of which are normally tasked with producing energy in the mitochondria, are also found sitting directly on top of human DNA, according to a study published today in Nature Communications.

9 Mar 2026

A New Framework for High-Efficiency Drug Development

A research team under the direction of the Medical University of Vienna has identified a potential new method for drug development in a recently published review.

9 Mar 2026

How Chromosomal Inversions Lock Beneficial Genes Together for Better Adaptation

When a species lives in two distinct types of habitats, individuals with traits better suited to each habitat will thrive and reproduce, naturally selecting descendants with those traits.

6 Mar 2026

Specialized Tanycyte Brain Cells Found to Play Key Role in Tau Clearance

Accumulation of the protein tau in the brain is one of the hallmarks of Alzheimer's disease. In a paper publishing March 5 in the Cell Press journal Cell Press Blue, researchers report a previously unknown mechanism that appears to enable the build-up of tau.

6 Mar 2026