Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Novel Approach Provides a Flexible Foundation for Measuring Coronavirus Protease Activity

A research team has computationally designed a synthetic peptide that enables modular detection of the enzymatic activity of coronavirus 3C-like protease (3CLPro), an enzyme essential for viral replication and maturation.

13 Aug 2026

Study Reveals Why People Are At Greater Risk of Fungal Infections Than Others

A study on Candida albicans uncovers immune mechanisms that prevent systemic infections, emphasizing the role of IL-1 cytokines and neutrophil response.

13 Aug 2026

Genomic Database Analysis Identifies New Target for Triple-Negative Breast Tumors

Triple-negative breast cancer accounts for approximately 15% of all breast cancer cases. It is characterized by the absence of estrogen receptor, progesterone receptor, and HER2 expression, rendering it insensitive to conventional endocrine and targeted therapies.

13 Aug 2026

Cells Deploy Specialized Quality Control Factors When Protein Synthesis Fails

Scientists at the Center for Molecular Medicine Cologne (CMMC) and the CECAD Cluster of Excellence on Aging Research have demonstrated in a biomedical study that ribosomes, the protein factories of our cells, face an unusually tough challenge when building large, membrane‑embedded proteins.

13 Aug 2026

New Roadmap Fixes Cellular Waste Accumulation to Halt Brain Degeneration

Researchers at University of California San Diego and their colleagues have identified a key cellular pathway that drives brain degeneration in both a rare childhood disorder and the far more common Alzheimer's disease.

13 Aug 2026

New Oral Nanomedicine Leverages Gut Metabolites to Destroy Tumors

A joint research team-led by Professor Young Seok Cho from the School of Medicine, alongside Professor James J. Moon from the University of Michigan-has successfully developed the world's first oral, microbiome-based nanomedicine.

12 Aug 2026

Scientists Map Overlapping Fluorescent Proteins Using Advanced Lifetime Microscopy Techniques

Fluorescent protein imaging is an indispensable tool in life science research, enabling visualization of protein movement and localization, gene expression, signaling pathways, protein-protein interactions, and more.

12 Aug 2026

Ancient Mitochondrial Signaling Pathway Regulates Vital Cellular Heme Levels

Heme, a bioactive form of iron, has numerous essential functions in the cell. As a key component of hemoglobin, it enables oxygen transport in the blood.

12 Aug 2026

Neural Stem Cell Protein CCN1 Guides Microglial Distribution During Development

The development of the central nervous system (CNS) depends on the coordinated interactions between neural stem cells (NSCs) and resident immune cells to regulate neurogenesis, tissue organization, and brain maturation.

12 Aug 2026

Batista Lab Identifies Crucial Protein Targets to Extend Malaria Vaccine Efficacy

A study reveals how targeting specific protein regions in malaria vaccines could enhance efficacy, potentially saving more lives in vulnerable populations.

11 Aug 2026

New Study Reveals How Genetic Mutations Hijack the Parkinson's LRRK2 Switch

Researchers at Weill Cornell Medicine have uncovered how a key Parkinson's protein called LRRK2 shifts between inactive and active forms, revealing the structural changes that enable certain mutations to push the protein into an overactive state.

11 Aug 2026

McMaster Team Identifies Natural Immune Defense Against Advanced Fatty Liver Disease

Researchers at McMaster University have discovered that a naturally occurring hormone best known for suppressing appetite and promoting weight loss also helps protect the liver from inflammation through a previously unknown signaling pathway, opening new possibilities for treating advanced fatty liver disease.

11 Aug 2026

Researchers Engineer AI Framework to Solve Longstanding Protein Isoform Mystery

A single human gene can produce multiple protein isoforms through alternative splicing, greatly expanding the functional diversity of the proteome.

11 Aug 2026

Researchers Uncover Molecular Defenses in Cold-Resilient Loquat

Loquat (Eriobotrya japonica) is an evergreen fruit tree whose winter growth and flowering make it especially vulnerable to sudden freezes.

10 Aug 2026

Bone Marrow T Cells Exhibit Conditional Preparedness Against Cancer

A team led by researchers from the German Cancer Research Center (DKFZ), the HI-STEM Stem Cell Institute, and Medical Clinic V at Heidelberg University Hospital (UKHD) has characterized T cells in the bone marrow in cases of multiple myeloma and acute myeloid leukemia: A specific group of tumor-reactive T cells can recognize and, in principle, fight cancer cells, but is often not sufficiently activated.

10 Aug 2026

New Research Reveals Cellular Switches Driving Physical Adaptation in Marine Species

In the animal kingdom, only those who adapt to their environment will survive. This adaptation comes in a wide range of forms, from invisible internal shifts in gene expression to dramatic anatomical changes, such as tadpoles growing legs and transitioning to life on land as frogs.

8 Aug 2026

Mapping Alternative RNA Splice Isoforms to Identify Novel Therapeutic Targets

Proteogenomics represents a transformative approach in cancer research that bridges the gap between genomic alterations and their functional consequences at the protein level.

8 Aug 2026

Research Reevaluates Crucial Microtubule Stabilizing Protein in Dementia Progression

A protein named tau, which has been highly implicated in the world's No. 1 cause of dementia - Alzheimer's disease - and several other neurodegenerative disorders, may spur these diseases in a way that differs greatly from the pathological pathway usually ascribed to it.

7 Aug 2026

Fruit Fly Genetics Explain How Early Embryos Dictate Head Development

One of the most important milestones in the early life of an organism is when the embryo breaks symmetry and arranges itself to form the head (anterior) at one end and tail (posterior) at the other end.

7 Aug 2026

Emerging m6A RNA Biology Explains Brain Vulnerability to Environmental Hazards

A growing understanding of RNA biology is reshaping how scientists view the relationship between environmental toxicants, brain development, and neurodegenerative disease.

7 Aug 2026