Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Gene-Edited Mosquitoes Block Malaria Transmission

Genetic modification of mosquitoes with the FREP1Q224 allele shows significant promise for malaria elimination, maintaining fitness and reducing infections.

31 Jul 2025

Researchers Identify Key Gene for Restoring Fertility in Hybrid Peppers

Cytoplasmic male sterility (CMS) systems have revolutionized hybrid seed production by eliminating the need for manual pollen removal.

30 Jul 2025

Bacterial Battle Strategies Involve Durable Amyloid Armor

Amyloids are perhaps best known as a key driver of Alzheimer's disease.

30 Jul 2025

PD-1 Guides T Cells to Become Long-Term Immune Defenders in the Skin

Weill Cornell Medicine researchers have discovered that PD-1—a molecule best known for putting the brakes on immune cells—also plays a critical role in helping T cells become long-term immune defenders in the skin.

30 Jul 2025

Proteins as a Natural Weapon Against Predatory Bacteria

Amyloids are perhaps best recognized as a major cause of Alzheimer’s disease.

30 Jul 2025

Blocking TG2 Could Help Immune Cells Attack Ovarian Tumors

The study reveals TG2's role in ovarian cancer metastasis, suggesting that its inhibition could re-educate the immune system for better anti-tumor efficacy.

30 Jul 2025

AI-Designed Proteins Offer New Hope for Personalized Cancer Immunotherapy

Precision cancer treatment on a larger scale is moving closer after researchers have developed an AI platform that can tailor protein components and arm the patient's immune cells to fight cancer.

29 Jul 2025

Stability in Proteins Is More Like Lego Than Jenga

Proteins are life's molecular workhorses, doing everything from turning sunlight into food to fighting viruses.

29 Jul 2025

Small Viral Protein ORF3a Reveals Big Role in SARS-CoV-2 Infectivity

In a recent study published in Nature Communications, researchers from the University of Chicago discovered that the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) uses a small but powerful protein, ORF3a, to assemble the infectious particles, making it more efficient at spreading the disease.

29 Jul 2025

Discovery of New Mitophagy Trigger Offers Hope for Parkinson’s Disease

Autophagy is essentially the 'rubbish collection' of our cells. If there are problems in this process, which is so important for our health, diseases such as Parkinson's can result. In their latest study, leading cell biologists at the Max Perutz Labs at the University of Vienna investigated mitophagy – a form of autophagy – and came to a remarkable conclusion: the researchers have described a new trigger for mitophagy.

29 Jul 2025

Multi-Omics Approaches Reveal New Insights into Colorectal Cancer Liver Metastasis

Colorectal cancer is among the most prevalent and lethal malignancies worldwide, with liver metastases occurring in nearly one-third of patients and accounting for a major share of cancer-related deaths.

29 Jul 2025

Tiny Artificial Cells Demonstrate Reliable 24-Hour Rhythms

A team of UC Merced researchers has shown that tiny artificial cells can accurately keep time, mimicking the daily rhythms found in living organisms.

29 Jul 2025

Rewriting rRNA Alters the Architecture of the Nucleolus

Ribosomes carry out the cell's most essential function-translating genetic information into proteins.

28 Jul 2025

New Insights into Yolk Protein Trafficking and Secretion in Worms

Yolk proteins (vitellogenins, VITs) are crucial lipid-carrying molecules that supply nutrients from the mother to embryos in oviparous animals.

28 Jul 2025

How DNA Packaging Shapes p53 Activity

Each cell in our bodies carries about two meters of DNA in its nucleus, packed into a tiny volume of just a few hundred cubic micrometers-about a millionth of a milliliter.

28 Jul 2025

Gene Editing Offers New Hope to Stop Malaria Transmission

Mosquitoes kill more people each year than any other animal. In 2023, the blood-sucking insects infected a reported 263 million people with malaria, leading to nearly 600,000 deaths, 80% of which were children.

24 Jul 2025

Neuron-Like Telocytes Directly Connect to Stem Cells in the Intestine

In a key advance for regenerative medicine and gut health, scientists from Duke-NUS Medical School and Nanyang Technological University, Singapore (NTU Singapore) have uncovered a precise and unexpected communication system in the gut.

24 Jul 2025

Gat3 Knockout Disrupts Visual Information Encoding in Mice

Cells called astrocytes are about as abundant in the brain as neurons, but scientists have spent much less time figuring out how they contribute to brain functions.

23 Jul 2025

New Insights into How Cilia Move and Power Cellular Motion

A team led by UT Southwestern Medical Center researchers has uncovered the atomic structure of a protein complex pivotal to the function of motile cilia, the hair-like structures extending from the surfaces of many cell types that generate their movement.

23 Jul 2025