Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Exploring the Flexible Structure of Sulfite Reductase Enzyme

Visualization of sulfite reductase's structure offers insights into sulfur chemistry, aiding in drug development and understanding bacterial energy sources.

28 May 2025

Study Reveals How APOE Isoforms Impact Brain Microglia

A study reveals how APOE isoforms influence microglial activity in Alzheimer's, highlighting the need for targeted interventions based on genetic risk factors.

28 May 2025

Epigenome Editing: Enhancing Endonuclease Protein Design for In Vivo Applications

Researchers have engineered a compact, high-specificity IscB variant, NovaIscB, for safe, persistent in vivo epigenome editing using AAV delivery, offering a powerful tool for gene regulation without DNA breaks.

28 May 2025

Cold Adaptation in Rice Offers New Insights into Evolution

Chinese researchers recently discovered molecular evidence supporting Lamarckism, a long-debated theory from the early 19th century that suggests acquired traits can be inherited.

27 May 2025

Peptide Metabolites: A New Frontier in Antiviral Therapies

Interest in antiviral treatments has grown significantly since the COVID-19 pandemic. Effective peptide treatments made from natural substances are in high demand right now due to the increased attention being paid to peptide-based drugs like Wegovy.

27 May 2025

Study Shows How Age-Related Metabolic Decline Impairs the Efficacy of CAR-T Cell Therapy

A Ludwig Cancer Research study has discovered that the metabolic decline that accompanies aging impairs the efficacy of CAR-T cell therapy, an immunotherapy in which T cells of the immune system are taken from patients, engineered to target cancer cells and reinfused into the same patients for treatment.

26 May 2025

New LLNL Method Accelerates Protein Screening for Drug Discovery

Machine learning and supercomputing have brought about a revolution in computational drug discovery.

24 May 2025

New Stem Cell Islet Model Mimics Pancreatic Function More Accurately

Researchers led by Maike Sander, Scientific Director of the Max Delbrück Center, have developed a vascularized organoid model of hormone secreting cells in the pancreas.

24 May 2025

RNA Editing and Transcriptional Switching Shape Fungal Antiviral Response

The expression of symptoms of viral infections is a byproduct of complex virus-host molecular pathways. These remain largely unknown, especially in the case of fungus-virus pathogen systems.

24 May 2025

Machine Learning Reveals Molecular Profile Differences in Colorectal Cancer Patients

Scientists aiming to advance cancer diagnostics have developed a machine learning tool that is able to identify metabolism-related molecular profile differences between patients with colorectal cancer and healthy people.

24 May 2025

Chemical Warfare Between Algae Threatens Kelp Forest Recovery

As the ocean warms across its temperate regions, kelp forests are collapsing and turf algae species are taking over.

24 May 2025

Scientists Engineer Proteins That Morph Like Nature’s Own

The ability to engineer shapeshifting proteins opens new avenues for medicine, agriculture, and beyond.

24 May 2025

Study Reveals How Introns Multiply and Move Across Genomes

DNA is the genetic code that provides the biological instructions for every living species, but not every bit of DNA helps the species survive. Some pieces of DNA are more like parasites, along for the ride and their own survival.

24 May 2025

Natural Deep Eutectic Solvents Enhance Yield and Antibacterial Activity of Zanthoxylum bungeanum

NADES treatments significantly boost essential oil yield and antibacterial activity in Zanthoxylum bungeanum, offering a natural solution to food contamination.

23 May 2025

Waters Acquires Halo Labs, Expanding Biological Analysis Portfolio

Waters Corporation today announced that it has acquired Halo Labs™, an innovator of specialized imaging technologies to detect, identify, and count interfering materials (particles) in therapeutic products, such as cell, protein, and gene therapies.

23 May 2025

Scientists Develop Method to Overcome Key Limitations of Cryo-EM

Sample loss has been a persistent problem in cryo-EM, a high-tech method for creating 3D models of molecules that reveals their inner structures.

22 May 2025

New Bacterial Consortium can Inhibit Bacterial Pathogens in Aquaculture

A new study by Danish researchers has demonstrated that it is possible to develop a consortium of bacteria that can inhibit bacterial pathogens in aquaculture.

22 May 2025

Unraveling the Co-Evolution of Human Height and Basal Metabolic Rate

Taller stature and a higher basal metabolic rate are two characteristics that distinguish modern humans from non-human primates. A genetic variant that helped these traits co-evolve was discovered by researchers and published in Cell Genomics.

22 May 2025

Cell Painting Technology Reveals Potential Cancer-Fighting Flavonoids

A team led by researchers at Baylor College of Medicine has identified flavonoids, natural compounds found in plants, that are toxic to bladder cancer cells cultured in the lab.

21 May 2025

Study Unveils Molecular Mechanism Behind Synapse Maturation

Researchers from the lab led by Prof. Joris De Wit (VIB-KU Leuven) have discovered an important clue to how connections between brain cells, known as synapses, mature.

21 May 2025