Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Novel Strategy for Combating High-Fat Diet-Induced Metabolic Dysfunction

Research on receptor FFA2 reveals how different activators influence metabolic processes, paving the way for innovative treatments for diabetes and obesity.

20 Jun 2025

Study Reveals TRF's Role in Reshaping Gut Microbiome and Metabolism

Metatranscriptomics uncovers how time-restricted feeding restores gut microbial cycles, offering insights into improving metabolic health and disease treatment.

20 Jun 2025

Organotypic Model of the Human Gut Epithelium Demonstrates Genetic Determinants of Shigella Colonization

A study in Nature Genetics uses organotypic gut models to reveal genome-wide genetic determinants of Shigella colonization, spotlighting type III secretion system effectors as crucial for early infection.

20 Jun 2025

Targeting RNA Polymerase 1 Rewires Cancer Cell Splicing and Halts Growth

Researchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences uncovered a new tumor-suppressive response that could lead to novel therapies targeting hard-to-treat cancers.

19 Jun 2025

Quantifying Breast Cancer Heterogeneity Through Single-Cell Transcriptomics

Tumors are complex systems characterized by variations across genetic, transcriptomic, phenotypic, and microenvironmental levels.

18 Jun 2025

New Inherited Disorder Impairs DNA Repair and Raises Cancer Risk

A new hereditary condition has been discovered that affects patients' ability to repair DNA – leaving them both at greater risk of developing blood cancer, and unable to repair some of the damage caused by chemotherapy treatments.

18 Jun 2025

Histone Variant H2AZ1 Identified as Key Driver of Stem Cell Aging

Cellular senescence-a state of irreversible growth arrest accompanied by chronic inflammation-is a major contributor to aging and tissue degeneration.

18 Jun 2025

Ancient Immune Sensor STING Found to Regulate Gut Microbe Tolerance

Thousands of bacterial and other microbial species live in the human gut, supporting healthy digestion, immunity, metabolism and other functions.

18 Jun 2025

Bio-Rad Extends Anti-Idiotypic Antibody and SpyCatcher Reagent Ranges for Bioanalysis and Antibody Drug Development

Bio-Rad Laboratories, Inc., a global leader in life science research and clinical diagnostics products, today extended its range of recombinant monoclonal anti-idiotypic antibodies with the introduction of antibodies specific to pertuzumab (Perjeta), guselkumab (Tremfya), canakinumab (Ilaris), belimumab (Benlysta), and the bispecific drug emicizumab (Hemlibra).

18 Jun 2025

Novel Tool moPepGen Uncovers Hidden Genetic Variants at the Protein Level

Scientists at UCLA and the University of Toronto have developed an advanced computational tool, called moPepGen, that helps identify previously invisible genetic mutations in proteins, unlocking new possibilities in cancer research and beyond.

17 Jun 2025

Evosep Joins P4ML to Power World’s Largest Multi-Omic Human Health Study of Two Million Samples

Evosep, a global leader in robust, high-throughput proteomics technologies, has been selected as the proteomics platform provider for the P4ML - OMICAssist Study—the world's largest multi-omic precision medicine initiative, launched by P4ML alongside its strategic academic, health regulatory, and semi-state partners in the United Arab Emirates.

From Evosep 17 Jun 2025

TUM Scientists Develop Breakthrough Method to Monitor CAR-T Cells

In modern immunotherapy, modified immune cells are introduced into the body to attack tumors and other targets.

16 Jun 2025

Llama Antibodies Provide Broad Protection Against Multiple Coronaviruses

Researchers identify small llama-derived antibodies that neutralize multiple coronaviruses, targeting a stable region of the spike protein for broad protection.

16 Jun 2025

Targeting iRhom2 to Control ADAM17-Related Diseases

The atomic structures of ADAM17 and iRhom2, revealed by UC researchers, offer new avenues for developing precise treatments for chronic inflammatory conditions.

16 Jun 2025

Study Shows Fibronectin Tension Loss Correlates With Breast Cancer Progression

Fibronectin fibers lose tension in invasive breast cancer, unlike in healthy or DCIS tissues, suggesting a mechanical marker for tumor progression.

16 Jun 2025

Study Reveals RNA Polymerase I Stalling Mechanism at Abasic DNA Damage Sites

New study shows RNA polymerase I halts at abasic DNA damage, helping prevent faulty rRNA production and exposing lesions for repair in dividing cells.

16 Jun 2025

Frog Egg Extracts Illuminate the Untangling Mechanism of DNA Knots

Research reveals how G-quadruplex DNA structures are untangled, highlighting a role for RNA in genome stability and potential cancer therapy strategies.

13 Jun 2025

Scientists Uncover Cyanobacteria’s Circadian Clockwork

The study uncovers how KaiC regulates circadian rhythms in cyanobacteria through a unique phosphorylation mechanism, offering insights into biological clocks.

13 Jun 2025

Semaphorin 3E Emerges as a Key Factor in Female Reproduction

The discovery of the Sema3E pathway in ovulation by Cornell researchers could enhance understanding of infertility and improve reproductive health strategies.

13 Jun 2025

Femtosecond Crystallography Reveals Cryptochrome Mechanisms

Research on cryptochromes using femtosecond crystallography uncovers rapid structural changes, enhancing our understanding of light-driven biological processes.

11 Jun 2025