Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Scientists Develop Method to Overcome Key Limitations of Cryo-EM

Sample loss has been a persistent problem in cryo-EM, a high-tech method for creating 3D models of molecules that reveals their inner structures.

22 May 2025

New Bacterial Consortium can Inhibit Bacterial Pathogens in Aquaculture

A new study by Danish researchers has demonstrated that it is possible to develop a consortium of bacteria that can inhibit bacterial pathogens in aquaculture.

22 May 2025

Unraveling the Co-Evolution of Human Height and Basal Metabolic Rate

Taller stature and a higher basal metabolic rate are two characteristics that distinguish modern humans from non-human primates. A genetic variant that helped these traits co-evolve was discovered by researchers and published in Cell Genomics.

22 May 2025

Cell Painting Technology Reveals Potential Cancer-Fighting Flavonoids

A team led by researchers at Baylor College of Medicine has identified flavonoids, natural compounds found in plants, that are toxic to bladder cancer cells cultured in the lab.

21 May 2025

Study Unveils Molecular Mechanism Behind Synapse Maturation

Researchers from the lab led by Prof. Joris De Wit (VIB-KU Leuven) have discovered an important clue to how connections between brain cells, known as synapses, mature.

21 May 2025

Compression Drives Aggressive Behavior in Liver Cancer Cells

Yale researchers are providing new insights into how physical forces, such as cells being compressed in physically restrictive environments, play key roles in cancer progression.

21 May 2025

TEAD Proteins Switch Partners to Drive Neural Cell Maturation

The basic mechanisms that control neural development are intricate, and as research from St. Jude Children's Research Hospital shows, the underlying motivations may even seem contradictory.

21 May 2025

Tracing the Evolution of Cyanobacterial Circadian Clocks Through Earth's History

Investigating ancient cyanobacterial timekeeping systems sheds light on the evolution of circadian rhythms and their significance in Earth's ecosystems.

21 May 2025

Zebrafish Study Warns of Ecological Risk from Tire-Related Water Contaminants

Emerging contaminants from rubber tires N-(1,3-Dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD) and its oxidation product 6PPD-quinone (6PPDQ)-are raising new red flags for aquatic ecosystems.

20 May 2025

Autophagy: A Double-Edged Sword in Cancer and Protein Conformational Disorders

A new FEBS Letters review explores the dual role of autophagy in cancer and protein misfolding diseases—highlighting its potential as a therapeutic target and the challenges of tipping the balance between protection and harm.

20 May 2025

Trace the Evolution of Malaria Parasite Proteins

Researchers at the Francis Crick Institute and the Gulbenkian Institute for Molecular Medicine (GIMM) have discovered that the evolution of a family of exported proteins in the malaria-causing parasite Plasmodium falciparum allowed it to infect people.

20 May 2025

How LEM-3 Cleaves DNA Bridges During Cell Division Revealed

If DNA bridges remain between chromosomes after cell division, chromosomes become improperly segregated, resulting in genetic instability and cancer.

20 May 2025

Study Resolves Longstanding Mystery of Ashwell-Morell Receptor

Study applies new techniques to reexamine a receptor linked to sepsis and resolve contradictions regarding its binding interactions with other proteins.

19 May 2025

Liver Energy Storage Tied to Genetic Activity in PPP1R3B

A new study published in Science Advances reveals that a single gene plays a big role in how the liver stores energy, a process that's critical for overall health and for managing diseases like type 2 diabetes.

19 May 2025

Addressing Protein Leakage in Cells to Improve the Accuracy of Single-Cell Proteomic Data

A new study in Nature Communications presents a solution to protein leakage in single-cell proteomics, improving data quality by identifying and excluding permeabilized cells using a machine learning classifier.

19 May 2025

Novel Bacterial Immune Weapon that Starves Viral Invaders

The discovery of Cat1 reveals how CARF effectors use complex structures to inhibit viral replication, advancing our understanding of bacterial immune responses.

19 May 2025

Molecular Mechanism Revealed by Stop-Motion Electron Microscopy

Using electron microscopy, researchers illustrate FusB's role in antibiotic resistance, providing a molecular-level understanding of fusidic acid interactions.

19 May 2025

Decoding a 3-Billion-Year-Old Cyanobacterial Nanodevice

Scientists unveil the structure of a light-harvesting nanodevice in ancient cyanobacteria, revealing insights into early oxygen-producing photosynthesis.

19 May 2025

Single Cell Sequencing Uncovers Hidden Drivers of Severe Celiac Disease

Scientists have identified mutated immune cell clones that could point to improved treatment for refractory celiac disease.

17 May 2025

New 3D Stem Cell Model Mimics Human Amniotic Sac Development

Researchers at the Francis Crick Institute have developed a new stem cell model of the mature human amniotic sac, which replicates development of the tissues supporting the embryo from two to four weeks after fertilization.

16 May 2025