Genome Editing News and Research

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Researchers use genome editing to facilitate drug discovery based on natural fungus

Rice University scientists have won federal support for their pursuit of novel drugs to treat human disease.

11 Aug 2020

Olympus and Cytosurge collaborate to deliver a complete single-cell and CRISPR genetic manipulation solution in the Americas

Olympus, a leading manufacturer of high-end research microscopes, and Cytosurge, a precision manufacturer of cell manipulation technologies, have entered a co-marketing agreement to become a complete system provider to the scientific community’s growing need for next-generation single-cell and CRISPR genetic manipulation solutions.

From Cytosurge AG 29 Jul 2020

Genome editing technologies can help understand disease-associated genetic mutations

Scientists have developed novel genome-editing technology that could help understand disease-related genetic mutations based on C-to-G single base variations.

27 Jul 2020

New startup launched to overcome the challenge of delivering next-generation therapeutics

Harvard University's Office of Technology Development (OTD) and the Harvard T.H. Chan School of Public Health today announced the launch of Vesigen Therapeutics, a startup company that aims to overcome the challenge of delivering next-generation therapeutics, such as gene-editing complexes, RNA molecules, and other large proteins, to intracellular targets in specific tissues of interest.

23 Jul 2020

Small, compact Cas proteins found in bacteriophages are ideal for gene editing

The DNA-cutting proteins central to CRISPR-Cas9 and related gene-editing tools originally came from bacteria, but a newfound variety of Cas proteins apparently evolved in viruses that infect bacteria.

20 Jul 2020

Hypercompact CRISPR enzyme from bacteriophages expands genome editing toolbox

A recently discovered hypercompact CRISPR enzyme found only in huge bacteriophages, and known as CRISPR-CasΦ, is functional, a new study by Patrick Pausch, Jennifer Doudna and colleagues reports, and it provides a powerful new tool in the CRISPR genome editing toolbox, including because it can target a wider range of genetic sequences compared to Cas9 and Cas12

17 Jul 2020

Scientists develop new genome editing methods for better crop yield

Although crop hybrid technologies have played a key role in considerably improving crop yield across the world in the past decades, developing and maintaining a hybrid production line has invariably been laborious and complex.

13 Jul 2020

New type of molecular editor can make precise changes in mitochondrial DNA

The genome in mitochondria -- the cell's energy-producing organelles -- is involved in disease and key biological functions, and the ability to precisely alter this DNA would allow scientists to learn more about the effects of these genes and mutations.

9 Jul 2020

RDP1 gene regulates the production of pollen grains

An international study has discovered a gene in the plant model Arabidopsis that reduces the number of pollen grains.

9 Jun 2020

Study reveals the relationship between genome folding and cellular functions

According to a study, the 3D structure of the human genome is fundamental to provide a quick and strong inflammatory response.

9 Jun 2020

Study investigates how cancer adapts its metabolism to overcome treatment

Knowing what cancer will do next could lessen the likelihood of it becoming resistant to treatment. A new Canadian study investigates how cancer adapts its metabolism to potentially overcome therapies still in development.

From University of Toronto 9 Jun 2020

C19ORF57 gene could advance reproductive medicine

The gene C19ORF57 has been identified to play a major role in meiosis by the Institute of Molecular Embryology and Genetics at Kumamoto University.

5 Jun 2020

New CRISPR-Cas9 based method for directed protein evolution

"Directed evolution" is the process by which scientists produce tailor-made proteins for cell biology, physiology and biomedicine in the laboratory.

28 May 2020

Using CRISPR/Cas molecular scissors to recombine entire chromosomes

The CRISPR/Cas molecular scissors work like a fine surgical instrument and can be used to modify genetic information in plants.

27 May 2020

Study shows how DNA mimic protein helps phages to attack their victims

A research team from the Severinov Laboratory at Skoltech, together with their collaborators from Israel and Switzerland, has analyzed a bacterial BREX defense mechanism that was poorly studied to date.

29 Apr 2020

Novel protein facilitates a critical event in mammalian fertilization

Fertilization is a fundamental process in sexual reproduction when the combination of male and female gametes blends genetic material to create a new unique individual. Now, researchers from Japan have identified a new factor that may help orchestrate this vitally complex life event.

From Osaka University 17 Apr 2020