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New machine learning model accurately predicts base editing outcomes

Gene editing technology is getting better and growing faster than ever before. New and improved base editors--an especially efficient and precise kind of genetic corrector--inch the tech closer to treating genetic diseases in humans.

15 Jun 2020

New research pairs spectroscopy with classic plant pathology diagnostics

Kaitlin (Katie) Gold is an assistant professor within the Plant Pathology and Plant-Microbe Biology section of the School of Integrative Plant Science at Cornell University. At her lab, the Grape Sensing, Pathology, and Extension Lab at Cornell AgriTech, she studies the fundamental and applied science of plant disease sensing.

11 Jun 2020

New minimally invasive method allows cells to be sampled over time

At any given moment, a variety of dynamic processes occur inside a cell, with many developing over time. Because current research methods for gene profiling or protein analysis destroy the cell, study is confined to just that one moment in time, and researchers are unable to return to the cell to examine how things change beyond that snapshot.

27 May 2020

Innovative tool to speed up the drug discovery process

A better understanding of the interaction between a molecule and the organism is important to consider its therapeutic potential.

21 May 2020

Researchers develop new AI model to bridge biology and chemistry

Insilico Medicine announces the publication of a new research paper titled "Molecular Generation for Desired Transcriptome Changes With Adversarial Autoencoders" in Frontiers in Pharmacology.

20 May 2020

The brain suppresses outside information during dreaming phase

Scientists from the CNRS and the ENS-PSL in France and Monash University in Australia have shown that the brain suppresses information from the outside world, such as the sound of a conversation, during the sleep phase linked to dreaming.

18 May 2020

AI accelerates drug discovery to fight COVID-19

A global race is underway to discover a vaccine, drug, or combination of treatments that can disrupt the SARS-CoV-2 virus, which causes the COVID-19 disease, and prevent widespread deaths.

24 Apr 2020

New database of 14,000 known macrolactones could aid future drug discovery

Researchers from North Carolina State University and Collaborations Pharmaceuticals have created a free-to-use database of 14,000 known macrolactones - large molecules used in drug development - which contains information about the molecular characteristics, chemical diversity and biological activities of this structural class.

22 Apr 2020

Identifying Potential Drugs Earlier In Discovery

Scientists have developed a technique that could significantly reduce the time of discovering potential new antibody-based drugs to treat disease.

16 Apr 2020

New method can improve access to sophisticated microscopy data

Researchers from the University of Michigan Life Sciences Institute (LSI) have created a novel data-processing method that offers a simpler yet faster way to data produced by cryo-electron microscopy (Cryo-EM) instruments, thus making it possible to adopt this robust method at a wider scale.

16 Apr 2020