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DiffInvex Reveals Genetic Escape Routes Used by Tumors Against Treatment

Just as species adapt over generations, our body's cells accumulate DNA changes throughout life. Most are harmless, yet a few "driver" mutations give a cell a competitive edge and can spark cancer.

14 May 2025

Study Reveals Muscle Memory at the Protein Level

Researchers have delved into the quantities of thousands of muscle proteins, uncovering a potential new explanation for the phenomenon of muscle memory.

16 Apr 2025

Hidden Causal Interaction Network Found in Cervical Cancer Cells

A Japanese research team has discovered a novel global cooperative phenomena of cell interactions in cervical cancer cells. Their findings suggest that the cells are metabolically connected in a functional network.

26 Mar 2025

New Chromosome Identification System Revolutionizes Alfalfa Research

In a recent study, scientists have developed a revolutionary chromosome identification system for alfalfa, one of the world's most economically vital forage crops.

19 Mar 2025

Genomics can Transform Care for Children with Rare Diseases

A simple genomics blood test could improve treatment and care for childhood epilepsy, but more investment is needed to make access fair and securely join up the data, finds a new study involving researchers at University College London (UCL) and Great Ormond Street Hospital for Children (GOSH).

8 Mar 2025

Rare Gene Variants Increase Type 2 Diabetes Prevalence in Asian Indian Families

A new study published in Communications Medicine, a Nature publication, details the discovery of rare gene variants that increase the prevalence of Type 2 diabetes in multiple generations of Asian Indian people.

27 Feb 2025

BioMed X and Merck Partnership Makes Significant Strides in Understanding ecDNA Biology

German independent research institute BioMed X announces the successful completion of its oncology research project in partnership with Merck. The data generated by this project has been acquired by Merck for further development, potentially leading to new therapeutic approaches in precision oncology.

10 Feb 2025

Uncovering the Ancient Genetic Secrets of Hornworts

Over 450 million years ago, plants began the epic transition from water to dry land. Among the first pioneers were the ancestors of humble hornworts, a group of small, unassuming plants that have persisted to this day.

7 Jan 2025

New Treatment Targets Tumor Microenvironment to Fight Breast Cancer

"Build your enemy a golden bridge to retreat across" is a piece of advice offered by Sun Tzu in his ancient military treatise, The Art of War. It turns out that cancerous growths adopt this strategy in their battle against the immune system.

24 Dec 2024

Biomaterials to Regenerate the Nervous System: Carl Zeiss Foundation Sponsors InteReg Project at Mainz University

Collaborative project involving Johannes Gutenberg University Mainz, the Max Planck Institute for Polymer Research, and the Leibniz Institute for Resilience Research will receive EUR 6 million.

11 Dec 2024

Mapping the Circadian Clock in the Drosophila Brain

All animals including humans are subject to daily rhythms in their activity and sleep, hunger, metabolism, and reproduction.

6 Dec 2024

Rising Temperatures Linked to Immune Decline in Capuchin Monkeys

The immune performance of wild capuchin monkeys declines when the animals experience higher temperatures, and younger monkeys seem to be particularly vulnerable to heat, according to a University of Michigan study.

2 Dec 2024

Researchers Discover GAME15's Role in Steroidal Compound Biosynthesis

Researchers at the Max Planck Institute for Chemical Ecology have identified GAME15 as a key protein that regulates the biosynthesis of both steroidal glycoalkaloids and steroidal saponins in plants of the genus Solanum.

21 Oct 2024

Living Microbes Unearthed in 2-Billion-Year-Old Rock

Pockets of microbes have been found living within a sealed fracture in 2-billion-year-old rock. The rock was excavated from the Bushveld Igneous Complex in South Africa, an area known for its rich ore deposits. This is the oldest example of living microbes being found within ancient rock so far discovered.

4 Oct 2024

COI1 Proteins in Maize Show Unexpected Functions for Crop Improvement

Maize (corn) is one of the most important staple crops in the world and has been extensively studied. Yet, many aspects of the genetic mechanisms regulating its growth and development remain unexplored.

19 Sep 2024

Genetic Mapping of Lyme Disease Bacteria Offers New Diagnostic and Treatment Possibilities

A genetic analysis of Lyme disease bacteria may pave the way for improved diagnosis, treatment and prevention of the tick-borne ailment.

19 Aug 2024

Unveiling the Genetic Secrets of Bacterial Iridescence

An international team of researchers has investigated the mechanism that makes some types of bacteria reflect light without using pigments.

10 Jul 2024

New Guidelines Address Ethical Concerns of Stem Cell Embryo Research in the UK

The UK’s first guidelines for research with stem cell-grown embryo models state that all studies involving these models should be overseen by a dedicated committee.

8 Jul 2024

Researchers Decode Impact of Every Possible Alteration in Critical Cancer Gene

Scientists at the Francis Crick Institute have mapped all possible outcomes of changes to a tumor-suppressing gene called VHL, as the first step in a massive research project to unravel the consequences of tens of thousands of genetic variations in genes linked to cancer.

4 Jul 2024

Ancestry Bias can Cause CRISPR Screens to Miss Cancer Dependencies

CRISPR/Cas9 gene editing has made possible a multitude of biomedical experiments including studies that systematically turn off genes in cancer cells to look for ones that the cancer cells heavily depend on to survive and grow.

17 Jun 2024