Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

AMSBIO launches new range of biosimilar antibodies for research use

AMSBIO has launched a new range of research grade biosimilars that enable analysis of biological processes without the need to purchase expensive therapeutic-grade biologics.

From AMS Biotechnology 15 Jul 2021

Nanobody mapping using NMR proves a promising alternative for therapeutic use

Researchers used NMR techniques to determine the structure of a nanobody, facilitating a better understanding of how the protein fights against diseases.

6 Jul 2021

Experimental model reveals the protective role of antioxidants in neurodegenerative disorders

Researchers used a model to replicate the blood-brain barrier and successfully demonstrated how antibody guards the brain against inflammation.

2 Jul 2021

Mutations on SARS-CoV-2 spike proteins create antibody-resistant variants

Researchers have identified how mutations on the SARS-CoV-2 spike protein separately create variants that are potentially resistant to antibodies.

1 Jul 2021

Higher density mediates receptor activation in immune cells

Researchers from the University of Southampton have discovered how tumor necrosis factor receptors, a crucial class of immune receptors, are activated.

28 Jun 2021

Chemical fingerprints help assess the reprogramming of regular cells into stem cells

The Nobel Prize-winning revelation that ordinary cells might be induced to revert to their earliest pluripotent state heralded the start of the ethical stem cell era.

28 Jun 2021

Study may help develop multi-pronged HIV eradication strategies

A team of researchers from the University of California - Davis Health (UC Davis) has made a breakthrough discovery of a unique type of stem cell that reduces the amount of the virus that causes AIDS.

From The University of California, Davis 25 Jun 2021

Epstein-Barr virus reactivation likely to blame for long COVID symptoms

Long COVID symptoms, such as weariness, brain fog, and rashes, may be caused by Epstein-Barr virus (EBV) reactivation because of the inflammatory response to coronavirus infection, which occurs in about 30% of individuals following recovery from initial COVID-19 infection.

25 Jun 2021

Antibody treatment reactivates the immune defense in advanced-stage cancer patients

Researchers at the University of Turku, Finland, showed that the antibody treatment reactivates the immune defense in patients with advanced-stage cancer. The treatment alters the function of the body's phagocytes and facilitates extensive activation of the immune system.

4 Jun 2021

Neutralizing antibodies are produced after SARS-CoV-2 infection

A research group from Osaka University led by Professor Hisashi Arase and consisting of researchers from the Research Institute for Microbial Diseases, the Institute for Protein Research, the Immunology Frontier Research Center, the Center for Infectious Diseases, and the Graduate School of Medicine has discovered for the first time that both neutralizing antibodies that protect against infection as well as infection-enhancing antibodies that increase infectivity are produced after infection with SARS-CoV-2 by analyzing antibodies derived from COVID-19 patients.

From Osaka University 26 May 2021

Study reveals urine protein biomarkers of bladder cancer

Oncotarget published "Urine protein biomarkers of bladder cancer arising from 16-plex antibody-based screens" which reported that the current study examines urine samples from 66 subjects, comprising of 31 Urology clinic controls and 35 bladder cancer patients, using a Luminex based screening platform.

24 May 2021

New probe allows real-time imaging of molecular orientations in live cells

Monitoring alignments of the building blocks of cells is important to understand how the cells are built. By collaborating with imaging scientists at the MBL, researchers from Japan have developed a new probe which they call POLArIS, allowing real-time imaging of molecular orientations in live cells.

17 May 2021

Newly designed higher affinity monoclonal antibody for cancer treatment

Recently, Prof. XIE Can from the High Magnetic Field Laboratory of the Hefei Institutes of Physical Science (HFIPS), in a collaboration with Prof. YAN Xiyun's lab from the Institute of Biophysics, reported the structural basis of mAb AA98's inhibition on CD146-mediated endothelial cells (EC) activation and designed higher affinity monoclonal antibody HA98 for cancer treatment.

10 May 2021

Low-dose administration of MERS DNA vaccine protects against COVID-19

The Wistar Institute has developed a synthetic DNA vaccine candidate for Middle East respiratory syndrome coronavirus (MERS-CoV).

26 Apr 2021

Natural molecule can effectively block the binding of human antibodies to SARS-CoV-2

Researchers have found that a natural molecule can effectively block the binding of a subset of human antibodies to SARS-CoV-2. The discovery may help explain why some COVID-19 patients can become severely ill despite having high levels of antibodies against the virus.

23 Apr 2021

SARS-CoV-2 infection produces antibodies that can destroy infected cells

Research teams investigated the antibodies generated in people with symptomatic or asymptomatic SARS-CoV-2 infection.

From Institut Pasteur 23 Apr 2021

Study finds raised levels of specific immune cells in asymptomatic people with COVID-19

The largest study of its type in the UK has identified differences in the immune response to COVID-19, between people with no symptoms, compared to those suffering a more serious reaction to the virus.

21 Apr 2021

Key discovery could prevent treatment failure in people with severe hemophilia A

Recently, researchers achieved a crucial discovery that could mitigate and eliminate immune responses causing treatment failure in people with hemophilia A.

20 Apr 2021

Antibodies may not inhibit SARS-CoV-2 variants from minks

It has been known for about a year that minks can become infected with SARS-CoV-2. The virus had been transmitted from humans to farmed mink and mutated in infected animals. Mutations were acquired in the spike protein, which is crucial for the entry of the virus into host cells and represents the central point of attack for antibodies.