Brain News and Research

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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Gene expression changes help understand the mechanism behind noise-induced hearing loss

A growing number of people are suffering from hearing loss due to exposure to loud noises from heavy machinery, concerts, or explosions. As a result, scientists have been working to understand the mechanism behind how the damage to hearing actually occurs.

30 Sep 2021

Stringent lineage tracing crucial for studies of nerve cell regeneration

UT Southwestern stem cell scientists find that stringent lineage tracing is crucial for studies of nerve cell regeneration. Their results, which are published in Cell, show that this tracing is far from routine in the field and suggest that earlier studies reporting "striking" regeneration results must be reexamined.

30 Sep 2021

Study examines effects of artificial sweetener on brain activity and appetite response

A synthetic aftertaste might not be the only side effect of switching to diet soda, especially if you're trying to lose weight.

29 Sep 2021

Study adds two new genetic variants to the list of glutamate receptor mutations

Researchers from Northwestern Medicine distinguished different variants of the gene GRIK2 that induces nonsyndromic neurodevelopmental disorder (NDD).

27 Sep 2021

Exploring cell and gene based therapies for Parkinson’s disease

After several decades of pre-clinical development, cell- and gene-based therapies for Parkinson's disease (PD) are now actively being explored. In this special supplement to the Journal of Parkinson's Disease on "Repairing the Parkinsonian Brain," experts highlight some of the current strategies being pursued to restore lost function and replace what is lost in the PD brain, with special emphasis on the challenges associated with translating advanced therapeutic approaches into pioneering clinical trials.

24 Sep 2021

Discovery may offer a promising new path for the study of multiple sclerosis

A surprising discovery may offer a promising new direction in the study of multiple sclerosis and other diseases of hypomyelination – when axons of neurons are not covered sufficiently in fatty sheaths (myelin), which disrupts communication between nerve cells.

23 Sep 2021

Microglial cells join together to break down toxic proteins more quickly

To break down toxic proteins more quickly, immune cells in the brain can join together to form networks when needed. This is shown by a joint study of the University of Bonn, the German Center for Neurodegenerative Diseases, and the Institut François Jacob in France.

23 Sep 2021

Naturally occurring protein that blocks inflammatory response linked to better stroke recovery in mice

A naturally occurring protein that blocks an inflammatory immune response was associated with better stroke recovery in a study conducted in mice, according to preliminary research to be presented at the American Heart Association's Vascular Discovery: From Genes to Medicine Scientific Sessions 2021.

23 Sep 2021

Study explores the benefits of the MIND diet for older adults

Scientists identified that older adults could take advantage of a specific diet named the MIND diet even when the protein deposits are developed.

23 Sep 2021

Prions may help yeast cope with rapidly changing environmental conditions

Prions are proteins found in the brain and familiar for their role in causing disease.

23 Sep 2021

Researchers reverse Kleefstra syndrome after birth in a mouse model

Scientists announced the reversal of Kleefstra syndrome—a genetic disorder leading to intellectual disability.

23 Sep 2021

Experts explore the organization of cancer cells and the influence of drug treatment

The changes that occur in individual cancer cells in due course detail the varied development of brain tumors.

23 Sep 2021

Study finds greater facial asymmetry in parents of autistic individuals

Recent research in Western Australia employs high-tech 3D facial scans to provide better knowledge of the genetic causes of autism.

21 Sep 2021

Automated computer program counts micronuclei from images of stained cells

Recently, scientists created an automated computer program that can precisely and reproducibly count micronuclei from microscope images.

21 Sep 2021

Study identifies vital factor involved in the evolution of the human brain

Humans have a huge and intricately folded neocortex, the reason for various intellectual abilities, setting apart humans from all other species.

17 Sep 2021

Hundreds of mutated tumor suppressor genes can help cancer cells evade the immune system

Hundreds of cancer-linked genes play a different role in causing disease than scientists had expected.

17 Sep 2021

Study opens new avenues for therapies against Charcot-Marie-Tooth disease

CMT, a rare hereditary condition, commences when genetic changes interrupt the transmission of nerve signals from the brain to the muscles of the extremities, specifically those of the lower limbs.

16 Sep 2021

Study uses mouse models to identify the likely cause of Alzheimer's disease

Ground-breaking new Curtin University-led research has discovered a likely cause of Alzheimer's disease, in a significant finding that offers potential new prevention and treatment opportunities for Australia's second-leading cause of death.

16 Sep 2021

Researchers reveal why nerve cell’s protein production slows down in CMT patients

A team led by MDC researcher Marina Chekulaeva has figured out why protein production slows down in the nerve cells of people suffering from Charcot-Marie-Tooth disease. This discovery could lead to a new therapeutic approach, the scientists report in the journal "Nucleic Acids Research".

16 Sep 2021

Researchers develop novel cell reprogramming strategy to slow down glioblastomas

Gliomas are the most common primary brain tumors in adults. Among them, high-grade glioblastomas (GBMs) are particularly known to be notoriously aggressive and invasive, which makes it challenging to treat them.

16 Sep 2021

Brain News and Research

Gene expression changes help understand the mechanism behind noise-induced hearing loss

Stringent lineage tracing crucial for studies of nerve cell regeneration

Study examines effects of artificial sweetener on brain activity and appetite response

Study adds two new genetic variants to the list of glutamate receptor mutations

Exploring cell and gene based therapies for Parkinson’s disease

Discovery may offer a promising new path for the study of multiple sclerosis

Microglial cells join together to break down toxic proteins more quickly

Naturally occurring protein that blocks inflammatory response linked to better stroke recovery in mice

Study explores the benefits of the MIND diet for older adults

Prions may help yeast cope with rapidly changing environmental conditions

Researchers reverse Kleefstra syndrome after birth in a mouse model

Experts explore the organization of cancer cells and the influence of drug treatment

Study finds greater facial asymmetry in parents of autistic individuals

Automated computer program counts micronuclei from images of stained cells

Study identifies vital factor involved in the evolution of the human brain

Hundreds of mutated tumor suppressor genes can help cancer cells evade the immune system

Study opens new avenues for therapies against Charcot-Marie-Tooth disease

Study uses mouse models to identify the likely cause of Alzheimer's disease

Researchers reveal why nerve cell’s protein production slows down in CMT patients

Researchers develop novel cell reprogramming strategy to slow down glioblastomas

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