Breast Cancer News and Research

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Breast cancer is cancer that forms in tissues of the breast, usually the ducts (tubes that carry milk to the nipple) and lobules (glands that make milk). It occurs in both men and women, although male breast cancer is rare. When breast cancer cells spread to other parts of the body, they are called metastases. There are different kinds of breast cancer. The kind of breast cancer depends on which cells in the breast turn into cancer. Breast cancer can begin in different parts of the breast, like the ducts or the lobes.

Anchor proteins inhibit a key metabolic driver involved in cancer and neuronal diseases

Certain anchor proteins inhibit a key metabolic driver that plays an important role in cancer and developmental brain disorders.

27 Jan 2021

New CAR T therapy could be more effective and less toxic against neuroblastoma

CAR T therapy has transformed the treatment for leukemia. Regrettably, the therapy is not effective enough to treat solid tumors, like neuroblastoma.

22 Jan 2021

Study defines the most crucial genes that Increase risk of breast cancer

Genetic inheritance affects the likelihood of developing breast cancer. Some genes are already known to increase cancer risk; other genes are suspected to be involved, but not to what extent. It is crucial to clarify this issue to improve prevention since it opens the way to more personalized follow-up and screening programs.

22 Jan 2021

Functions of gamma delta T cells are regulated by sugars and fat Gene, shows study

The team led by Bruno Silva Santos, Principal Investigator and Deputy Director of the Instituto de Medicina Molecular João Lobo Antunes (iMM) and Professor at the Faculdade de Medicina da Universidade de Lisboa, discovered that the functions of a subtype of white blood cells - gamma delta T cells - are regulated by metabolic resources, namely sugars and fat.

20 Jan 2021

Study shows how nonmalignant cells adapt to harsh tumor microenvironment

Cells need energy to survive and thrive. Generally, if oxygen is available, cells will oxidize glucose to carbon dioxide, which is very efficient, much like burning gasoline in your car. However, even in the presence of adequate oxygen, many malignant cells choose instead to ferment glucose to lactic acid, which is a much less efficient process.

20 Jan 2021

Researchers define cancer invasion machinery orchestrated by cancer gene

Researchers at the University of Helsinki have defined a cancer invasion machinery, which is orchestrated by a frequently mutated cancer gene called Ras. When signaling from Ras protein becomes abnormally high, like it does in many cancers, this switches on the cellular machinery that helps the cancer cells to depart from the tissue from which the cells have developed.

20 Jan 2021

New computational technique accurately differentiates between normal and cancer cells

Scientists have created a new method to precisely differentiate between data from a wide range of normal cells and cancer cells found inside tumor samples.

19 Jan 2021

Study reveals unusual chemical steps involved in the synthesis of antibiotics

Pictures of a protein that plays a key role in the production of a potent antibiotic have disclosed the first unusual steps involved in the synthesis of antibiotics.

From Penn State University 19 Jan 2021

Targeting RNA splicing can trigger antiviral immune pathways in triple-negative breast cancers

Researchers at Baylor College of Medicine have discovered how therapeutics targeting RNA splicing can activate antiviral immune pathways in triple negative breast cancers (TNBC) to trigger tumor cell death and signal the body's immune response.

15 Jan 2021

Microbe found in the colon may promote breast cancers

A microbe found in the colon and commonly associated with the development of colitis and colon cancer also may play a role in the development of some breast cancers, according to new research from investigators with the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

7 Jan 2021

Combination method can boost immunotherapy for breast cancer

According to a new study performed by scientists from the University of North Carolina, stimulating an immune signaling pathway, which is best known for combating bacterial and viral infections, can increase the potential of genetically engineered T cells to remove breast cancer in mice.

4 Jan 2021

Chromosomal instability is associated with cancer's aggressiveness

Cancer cells are known for spreading genetic chaos. As cancer cells divide, DNA segments and even whole chromosomes can be duplicated, mutated, or lost altogether.

29 Dec 2020

Researchers detect new immune cells that act as major driver of breast cancer growth

Several breast cancer immunotherapies have had only minimal success in treating the aggressive forms of this disease.

17 Dec 2020

Scientists invent new RNA drug-discovery tool for undruggable diseases

Imagine trying to throw a bullseye when the dartboard lies buried within a crumpled box. That's the challenge faced by scientists working to make new medicines for some "undruggable" diseases, including a type of metastatic breast cancer.

16 Dec 2020

New genomic tool can accurately assess the risk of breast cancer

Breast cancer is the most commonly diagnosed disease in women and is the main cause of cancer-related mortalities in this group of population.

15 Dec 2020

Study reveals new target to make breast cancer more sensitive to immunotherapy

Although immunotherapy has been effective in treating different kinds of cancer, it is still unsuccessful when it comes to treating breast cancers.

11 Dec 2020

Appendiceal cancer among young patients harbors a distinct biology, shows study

The first study to compare molecular landscapes of early-onset and late-onset appendiceal cancer has revealed distinct non-silent mutations in the tumors of younger patients, setting the stage for the development of potential therapeutic advances for this rare disease.

From Vanderbilt University 10 Dec 2020

Breast Cancer News and Research

Anchor proteins inhibit a key metabolic driver involved in cancer and neuronal diseases

New CAR T therapy could be more effective and less toxic against neuroblastoma

Study defines the most crucial genes that Increase risk of breast cancer

Functions of gamma delta T cells are regulated by sugars and fat Gene, shows study

Study shows how nonmalignant cells adapt to harsh tumor microenvironment

Researchers define cancer invasion machinery orchestrated by cancer gene

New computational technique accurately differentiates between normal and cancer cells

Study reveals unusual chemical steps involved in the synthesis of antibiotics

Targeting RNA splicing can trigger antiviral immune pathways in triple-negative breast cancers

Microbe found in the colon may promote breast cancers

Combination method can boost immunotherapy for breast cancer

Chromosomal instability is associated with cancer's aggressiveness

Researchers detect new immune cells that act as major driver of breast cancer growth

Scientists invent new RNA drug-discovery tool for undruggable diseases

New genomic tool can accurately assess the risk of breast cancer

Study reveals new target to make breast cancer more sensitive to immunotherapy

Appendiceal cancer among young patients harbors a distinct biology, shows study

CTC dynamics related to overall survival in patients with metastatic breast cancer

Environmental and exogenous compounds can interact with therapeutic drugs, shows study

Researchers identify key target that allows cancer cells to spread more efficiently

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