Breast Cancer News and Research

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Breast cancer is cancer that forms in tissues of the breast, usually the ducts (tubes that carry milk to the nipple) and lobules (glands that make milk). It occurs in both men and women, although male breast cancer is rare. When breast cancer cells spread to other parts of the body, they are called metastases. There are different kinds of breast cancer. The kind of breast cancer depends on which cells in the breast turn into cancer. Breast cancer can begin in different parts of the breast, like the ducts or the lobes.

Targeting MAPK4 in triple-negative breast cancer may lead to improved treatments

Scientific evidence supporting the involvement of the enzyme MAPK4 in cancer growth and resistance to certain therapies has been growing quickly.

12 Jan 2022

Olfactory receptor gene may drive breast cancer metastasis to the brain

An olfactory receptor gene that aids in the sense of smell may also play a role in the metastasis of breast cancer to the brain, bones and lung, researchers from Massachusetts General Hospital have found.

4 Jan 2022

Researchers develop novel technique to monitor remote immune mechanisms

The human immune system works hard to maintain an individual’s health and protect against viruses, bacteria, parasites, fungi, and cancerous cells.

17 Dec 2021

New classification method divides breast cancers into 12 distinct biological groups

Researchers at UNC Lineberger Comprehensive Cancer Center have taken a major step forward in melding two key methods for studying breast cancer: one by genetic analysis and the second by looking at the architecture of cells, or their pathology.

9 Dec 2021

Single-cell spatial analysis may provide information about neoadjuvant therapy for triple-negative breast cancer

A next-generation technology that allows the study of protein expression at the single-cell level and the location of the cells within the tumor microenvironment (TME) was feasible and provided information on the benefit of adding the immune checkpoint inhibitor atezolizumab (Tecentriq) to chemotherapy as neoadjuvant treatment for patients with early high-risk and locally advanced triple negative breast cancer (TNBC), according to results presented at the San Antonio Breast Cancer Symposium, held December 7-10, 2021.

8 Dec 2021

Researchers show that tumor cells contribute differently to the formation of metastases

A type of cell transformation known as EMT enables cancer cells to break away from the tumor and form metastases elsewhere.

30 Nov 2021

Treatment with common allergy medication linked to improved immunotherapy response

New research from The University of Texas MD Anderson Cancer Center found that treatment with antihistamines, a commonly used allergy medication, was associated with improved responses to immune checkpoint inhibitors.

29 Nov 2021

Novel therapeutic approach forces cancer cells to dormancy, prevents metastasis

A novel therapeutic approach inhibits the growth of metastatic tumors in mice by coercing cancer cells into a dormant state—where they cannot proliferate.

25 Nov 2021

Cancer cells disarm immune cells by hijacking mitochondria, says research

Researchers utilized the power of nanotechnology to identify a novel means that cancer cells use to disarm their would-be cellular attackers.

19 Nov 2021

Cancer invasion and migration can be suppressed by manipulating stiffness of cell membrane

A research collaboration has found that cancer invasion and migration in mice can be inhibited by controlling the stiffness of the cell membrane.

10 Nov 2021

Cancer cells change their shape and migration modes more often, says research

Recent research from the Oregon State University shows how malignant cells change their shape and migration techniques to attack various tissues.

29 Oct 2021

Study offers novel therapeutic opportunities to prevent breast tumor recurrence

Researchers examined tumor cells that were resistant to the original treatment and identified molecular targets for therapies that could evade breast cancer recurrence.

28 Oct 2021

Researchers uncover previously unknown interactions between proteins that drive cancers

In three studies from the Cancer Cell Map Initiative, researchers uncovered previously unknown interactions between proteins that drive cancer and combined this new data to generate a map of protein pathways informing cancer outcomes.

1 Oct 2021

Circulating tumor cells found to form clusters that cause breast cancer metastases

A new study reports that circulating tumor cells that exhibit the features of stem cells employ ICAM1 to enable the formation of CTC clusters.

24 Sep 2021

Researchers seek to point a way toward a unified theory for DNA folding

At more than 2 meters long, the human DNA molecule uses intricate folding patterns to fit into cells while locally unfolding to express genes. Such phenomena, however, are difficult to measure in experiments, and theoretical frameworks explaining them continue to be at odds with one another.

22 Sep 2021

Breast Cancer News and Research

Targeting MAPK4 in triple-negative breast cancer may lead to improved treatments

Olfactory receptor gene may drive breast cancer metastasis to the brain

Researchers develop novel technique to monitor remote immune mechanisms

New classification method divides breast cancers into 12 distinct biological groups

Single-cell spatial analysis may provide information about neoadjuvant therapy for triple-negative breast cancer

Researchers show that tumor cells contribute differently to the formation of metastases

Treatment with common allergy medication linked to improved immunotherapy response

Novel therapeutic approach forces cancer cells to dormancy, prevents metastasis

Cancer cells disarm immune cells by hijacking mitochondria, says research

Cancer invasion and migration can be suppressed by manipulating stiffness of cell membrane

Cancer cells change their shape and migration modes more often, says research

Study offers novel therapeutic opportunities to prevent breast tumor recurrence

Researchers uncover previously unknown interactions between proteins that drive cancers

Circulating tumor cells found to form clusters that cause breast cancer metastases

Researchers seek to point a way toward a unified theory for DNA folding

Scientists find two proteins that pair up to build lifelines to cancer cells

New genetic classifier can predict the sensitivity of chemotherapy for breast cancer

New treatment developed from plant virus could keep metastatic cancers at bay

Eosinophils combat cancer metastases in the lungs, says research

Scientists develop a novel approach to analyze tumor evolution

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