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Study reports first-ever application of CRISPR-Cas12b system in plant genome engineering

Study reports first-ever application of CRISPR-Cas12b system in plant genome engineering

In a study reported recently in Nature Plants, Yiping Qi—assistant professor of Plant Science at the University of Maryland—has found a new CRISPR genome engineering system, called CRISPR-Cas12b, that is viable in plants for the first time.

10 Mar 2020

Study explores the impact of solute carriers on the activity and potency of cytotoxic drugs

Study explores the impact of solute carriers on the activity and potency of cytotoxic drugs

At the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, scientists have investigated how solute carriers (SLCs)—a large class of membrane transport proteins—affect the activity and potency of cytotoxic drugs, for example, those used to treat leukemia and other cancers.

10 Mar 2020

New chromosome-level detectors developed to monitor cellular activity

New chromosome-level detectors developed to monitor cellular activity

For researchers investigating the regulatory processes in cells that are vital to all life, an innovative system that amplifies gene expression signals could be a turning point.

10 Mar 2020

WDR74 modulates melanoma tumorigenesis and metastasis through the RPL5–MDM2–p53 pathway

WDR74 modulates melanoma tumorigenesis and metastasis through the RPL5–MDM2–p53 pathway

A team of scientists has discovered that the WDR74 protein plays a vital role in metastasis progression in lung cancer and melanoma primary tumors.

22 Feb 2020

A new study finds a potential immunotherapeutic pan-target on cancer cells

A new study finds a potential immunotherapeutic pan-target on cancer cells

In a genome-wide CRISPR-Cas9 screen published in Nature Immunology in January 2020, a group of researchers described a potential universal target on cancer cells.

12 Feb 2020

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