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Human immune system may play a key role in shaping the microbiome composition

The gut is an unusually noisy place, where hundreds of species of bacteria live alongside whatever microbes happen to have hitched a ride in on your lunch.

30 Oct 2020

'Training’ the innate immunity may improve the success of immunotherapy

Immunotherapies, such as checkpoint inhibitor drugs, have made worlds of difference for the treatment of cancer. Most clinicians and scientists understand these drugs to act on what's known as the adaptive immune system, the T cells and B cells that respond to specific threats to the body.

30 Oct 2020

Scientists discover new anti-cancer molecule

A group of Moscow scientists has discovered and explained the activity mechanism of a new anti-cancer molecule -- diphenylisoxazole. This molecule has been shown to be effective against human cancer cells. The research, published in the journal Bioorganic & Medicinal Chemistry Letters, makes it possible to produce an affordable cancer treatment drug.

30 Oct 2020

Severe ulcerative colitis linked to newly-discovered strain of oral bacteria

Severe ulcerative colitis - a form of inflammatory bowel disease (IBD) - has been linked to a newly-discovered strain of oral bacteria, a study led by UNSW Sydney has found.

From The University of New South Wales (UNSW) 30 Oct 2020

Researchers describe how drug use change specific brain cells responsible for motivation

In the October 28, 2020 issue of the Journal of Neuroscience, researchers from the Medical University of South Carolina and the National Institutes of Health describe how reminders of drug use can change specific brain cells responsible for motivation, increasing the desire to seek drugs.

30 Oct 2020

Scientists reveal molecular mechanism that increases the invasiveness of radioresistant cancer cells

Scientists have revealed the molecular mechanism regulating the trafficking of lysosomes that increases the invasiveness of radioresistant cancer cells following radiotherapy.

30 Oct 2020

Scientists sequence full genome of ornamental variety of miscanthus

An international research team has sequenced the full genome of an ornamental variety of miscanthus, a wild perennial grass emerging as a prime candidate for sustainable bioenergy crops.

30 Oct 2020

Scientists discover link between two signaling pathways crucial to growth of colon cancer

In breakthrough colon cancer research, scientists at ChristianaCare's Helen F. Graham Cancer Center & Research Institute have discovered a link between two key signaling pathways crucial to the development and growth of colon cancer. The study is published today in the journal PLOS ONE.

29 Oct 2020

Individuals infected with mild-to-moderate COVID 19 mount a robust antibody response

The vast majority of individuals infected with mild-to-moderate COVID 19 mount a robust antibody response that is relatively stable for at least five months, according to research conducted at the Icahn School of Medicine at Mount Sinai and published October 28, in the journal Science.

29 Oct 2020

Sodium bicarbonate can reprogram T cells in leukemia patients

Scientists have discovered that sodium bicarbonate - also known as baking soda or bicarbonate of soda - can reprogram T cells in leukemia patients to resist the immune-suppressing effects of cancer cells, which can drive leukemia relapse after stem cell transplants.

29 Oct 2020

Researchers receive $2.6 million grant to examine tau-glycan interactions involved in Alzheimer's disease

Tangles of misfolded tau proteins in the brain are closely associated with memory loss in patients with Alzheimer's disease.

29 Oct 2020

Researchers develop RNA catalyst that sheds light on evolution

Enzymes enable biochemical reactions that would otherwise not take place on their own. In nature, it is mostly proteins that function as enzymes.

29 Oct 2020

Scientists develop controllable system for mimicking biochemical reaction cascades in cells

Researchers at the University of Basel have developed a precisely controllable system for mimicking biochemical reaction cascades in cells. Using microfluidic technology, they produce miniature polymeric reaction containers equipped with the desired properties.

29 Oct 2020

Genetic predispositions affect the efficacy of COVID-19 drugs

A paper recently uploaded to bioRxiv* aimed to utilize genome-wide CRISPR screening to identify genes involved in modulating the activity of COVID-19 drugs.

29 Oct 2020

Myeloid cell can suppress the immune response to tumor cells

For a long time, researchers had believed that the brain reduces inflammation by protecting itself from an aggressive immune response.

28 Oct 2020

Scientists use new model to develop specific cancer immunotherapy

The function of the body’s immune system is to defeat diseases by detecting foreign invaders and then mounting a response against these pathogens.

28 Oct 2020

Study shows how cancer remodels human chromosomes for its own purposes

Scientists have shown that cancer rebuilds the architecture of human chromosomes, which allows the disease to take hold and spread.

28 Oct 2020

Researchers map molecular structure of CV30 antibody to neutralize coronavirus

Scientists at Fred Hutchinson Cancer Research Center in Seattle have shown that a potent antibody from a COVID-19 survivor interferes with a key feature on the surface of the coronavirus's distinctive spikes and induces critical pieces of those spikes to break off in the process.

28 Oct 2020

Scientists identify physiological mechanism that maintains regenerative capacity of muscle stem cells

Researchers at UPF, the National Centre for Cardiovascular Research, ICREA and Ciberned have identified a physiological mechanism that maintains the regenerative capacity of muscle stem cells, and surprisingly resists the passage of time far more than expected, until geriatric age.

28 Oct 2020

Researchers use new technique to find undetectable ‘hot spots’ inside aggressive breast cancer

Using a new technique, a team of McGill University researchers has found tiny and previously undetectable 'hot spots' of extremely high stiffness inside aggressive and invasive breast cancer tumors.

28 Oct 2020

Cell News and Research

Human immune system may play a key role in shaping the microbiome composition

'Training’ the innate immunity may improve the success of immunotherapy

Scientists discover new anti-cancer molecule

Severe ulcerative colitis linked to newly-discovered strain of oral bacteria

Researchers describe how drug use change specific brain cells responsible for motivation

Scientists reveal molecular mechanism that increases the invasiveness of radioresistant cancer cells

Scientists sequence full genome of ornamental variety of miscanthus

Scientists discover link between two signaling pathways crucial to growth of colon cancer

Individuals infected with mild-to-moderate COVID 19 mount a robust antibody response

Sodium bicarbonate can reprogram T cells in leukemia patients

Researchers receive $2.6 million grant to examine tau-glycan interactions involved in Alzheimer's disease

Researchers develop RNA catalyst that sheds light on evolution

Scientists develop controllable system for mimicking biochemical reaction cascades in cells

Genetic predispositions affect the efficacy of COVID-19 drugs

Myeloid cell can suppress the immune response to tumor cells

Scientists use new model to develop specific cancer immunotherapy

Study shows how cancer remodels human chromosomes for its own purposes

Researchers map molecular structure of CV30 antibody to neutralize coronavirus

Scientists identify physiological mechanism that maintains regenerative capacity of muscle stem cells

Researchers use new technique to find undetectable ‘hot spots’ inside aggressive breast cancer

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