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DNA structural changes play key role in the recovery phase after DNA damage

A research team from Cologne has discovered that a change in the DNA structure - more precisely in the chromatin - plays a decisive role in the recovery phase after DNA damage. The key is a double occupation by two methyl groups on the DNA packaging protein histone H3 (H3K4me2).

15 Oct 2020

A new protein discovered that repairs DNA

Researchers have identified a new protein that makes it possible to repair DNA. The protein in question is called cryptochrome.

15 Oct 2020

Novel mechanism restores cell function after DNA damage

Scientists have found that a modification in the DNA structure— specifically in the chromatin—plays a key role in the recovery stage following DNA damage.

15 Oct 2020

Scientists identify heart cells responsible for repairing damaged heart after infarction

A global study has discovered the heart cells responsible for repairing the damage induced to this vital organ following infarction.

15 Oct 2020

Study reveals molecular mechanism that regulates filament-like proteins in heart muscles

Heart muscle cells contain filament-like proteins that should have the same precise length, so that they can perfectly synchronize.

15 Oct 2020

A combinational approach to fight against cancer

In their quest to destroy cancer cells, researchers are turning to combinational therapies more and more. Scientists from Germany and China have now combined a chemotherapeutic and photodynamic approach.

14 Oct 2020

Scientists discover key parameters to better predict cancer-killing effect of neoantigens

Neoantigens, tiny markers that arise from cancer mutations, flag cells as cancerous and could be the key to unlocking a new generation of immunotherapies.

14 Oct 2020

Researchers unravel molecular factors that drive severity of COVID-19

While most COVID-19 cases are asymptomatic or mild, severe complications associated with acute respiratory distress have led to more than one million deaths worldwide in just several months.

14 Oct 2020

Immunotherapy using CAR NKT cells shows promise for treating solid tumors

Natural killer T (NKT) cells, a type of immune cells known for their potent anti-cancer properties in murine tumor models, have been developed into a novel form of immunotherapy to treat patients with cancer.

14 Oct 2020

Researchers discover new gene involved in the architecture of grass inflorescence

The “spikelet meristem,” or SM for short, has a crucial role to play during the development of the grass inflorescence.

14 Oct 2020

Dynamic map shows how immune cells fight microbes and remember future infections

Scientists have plotted the activity of an unlimited number of genes in the immune cells of mice over the course of an infection.

14 Oct 2020

New software helps analyze individual cells in virtual reality

New virtual reality software now enables scientists to “walk” inside and examine individual cells.

14 Oct 2020

Study could explain why some people are severely affected by Bardet-Biedl syndrome

Geneticists usually split disorders into “simple”, where mutations in several genes contribute modest quantities.

13 Oct 2020

Treatment using immune system T cells preserves vision of mice with retinoblastoma

A treatment that uses immune system T cells, combined with an immune-boosting drug packaged in an injectable gel, was found to preserve the vision of mice implanted with tissue from a human eye cancer known as retinoblastoma.

13 Oct 2020

New computational biology algorithm may enable more effective cellular therapies

Cellular therapy is a powerful strategy to produce patient-specific, personalised cells to treat many diseases, including heart disease and neurological disorders. But a major challenge for cell therapy applications is keeping cells alive and well in the lab.

13 Oct 2020

VAV1 gene mutations may promote growth of T-cell tumors in laboratory mice

Life is an exquisite orchestration of growth and change, with checks and balances that fine-tune complex entwined interactions, both intrinsic and external.

13 Oct 2020

Researchers discover a new mechanism to regulate nerve impulses

Researchers at Linköping University, Sweden, have discovered a new mechanism by which substances can open a certain type of ion channel and in this way regulate nerve impulses.

13 Oct 2020

Research focuses on understanding production of memory B cells and immune responses

The current COVID-19 climate has made vaccines, antibodies, and immune responses topics of everyday conversation. Now, it isn't just immunologists who want to know how our bodies respond to re-infections months, years, or sometimes decades after an initial immune response.

From Osaka University 13 Oct 2020

Study clarifies role of ERβ in growth and regeneration of skeletal muscle in female mice

Researchers at Kumamoto University, Japan generated mice lacking the estrogen receptor beta (ERβ) gene, both fiber-specific and muscle stem cell-specific, which resulted in abnormalities in the growth and regeneration of skeletal muscle in female mice.

13 Oct 2020

Stem cells that promote bone repair can also generate arthritic bone spurs

The same stem cells that heal broken bones can also generate arthritic bone spurs called osteophytes, according to a new study in the Annals of the Rheumatic Diseases.

13 Oct 2020

Cell News and Research

DNA structural changes play key role in the recovery phase after DNA damage

A new protein discovered that repairs DNA

Novel mechanism restores cell function after DNA damage

Scientists identify heart cells responsible for repairing damaged heart after infarction

Study reveals molecular mechanism that regulates filament-like proteins in heart muscles

A combinational approach to fight against cancer

Scientists discover key parameters to better predict cancer-killing effect of neoantigens

Researchers unravel molecular factors that drive severity of COVID-19

Immunotherapy using CAR NKT cells shows promise for treating solid tumors

Researchers discover new gene involved in the architecture of grass inflorescence

Dynamic map shows how immune cells fight microbes and remember future infections

New software helps analyze individual cells in virtual reality

Study could explain why some people are severely affected by Bardet-Biedl syndrome

Treatment using immune system T cells preserves vision of mice with retinoblastoma

New computational biology algorithm may enable more effective cellular therapies

VAV1 gene mutations may promote growth of T-cell tumors in laboratory mice

Researchers discover a new mechanism to regulate nerve impulses

Research focuses on understanding production of memory B cells and immune responses

Study clarifies role of ERβ in growth and regeneration of skeletal muscle in female mice

Stem cells that promote bone repair can also generate arthritic bone spurs

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