Chemotherapy News and Research

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Chemotherapy, in its most general sense, is the treatment of disease by chemicals especially by killing micro-organisms or cancerous cells. In popular usage, it refers to antineoplastic drugs used to treat cancer or the combination of these drugs into a cytotoxic standardized treatment regimen.

Cell nucleus may enable the cells to evade crowded environments

Like people, cells in the human body protect their personal space. They seem to know how much space they need, and if it gets too tight, most cells prefer to break free.

20 Oct 2020

New nanoparticles can destroy drug-resistant cancer cells

Multidrug resistance, or MDR, is a process in which tumors become impervious to numerous drugs and is a major cause of failure in cancer chemotherapy.

19 Oct 2020

Treatment using immune system T cells preserves vision of mice with retinoblastoma

A treatment that uses immune system T cells, combined with an immune-boosting drug packaged in an injectable gel, was found to preserve the vision of mice implanted with tissue from a human eye cancer known as retinoblastoma.

13 Oct 2020

Immune cell biomarker may help identify patients at risk for graft-versus-host disease

A recent report published in Science Translational Medicine by MUSC Hollings Cancer Center investigator Sophie Paczesny, M.D., Ph.D., sheds light on immune cell biomarkers that may reveal which patients are most at risk for graft-versus-host disease (GVHD), a life-threatening condition that can arise after hematopoietic stem cell transplantation (HSCT) for treatment of liquid cancers such as leukemia.

8 Oct 2020

New drug shows promise in the treatment of neuroblastoma

A drug has shown great promise in the treatment of neuroblastoma, an aggressive form of childhood cancer. The study was led by researchers at Lund University in Sweden, and is published in the journal Science Translational Medicine.

7 Oct 2020

Genetic test identifies patients with invasive lobular carcinoma at high risk of recurrence

New results to be presented at the 12th European Breast Cancer Conference show that a test, which looks at the activity of 70 genes in breast cancer tissue, is possible to use in the clinic to identify patients with invasive lobular carcinoma (ILC) that is at high risk of recurring and progressing.

1 Oct 2020

Researchers identify key molecules that contribute to radioresistance in glioblastoma

Scientists have identified key molecules that mediate radioresistance in glioblastoma multiforme; these molecules are a potential target for the treatment of this brain cancer.

1 Oct 2020

Scientists identify a novel approach to regulate cell plasticity

Cell plasticity is a property by which a cell can take on different and reversible identities. Cell plasticity is also essential for embryo development and for the correct function of the immune system.

29 Sep 2020

New precision drug targeting cancer's ability to repair DNA shows promise

A new precision drug which stops cancer from repairing its DNA has shown promise in an early-stage clinical trial - highlighting the potential of a new class of drugs known as ATR inhibitors.

29 Sep 2020

T-cell-based vaccine strategy provides broader protection against influenza

As Americans begin pulling up their sleeves for an annual flu vaccine, researchers at the University of Wisconsin-Madison have provided new insights into an alternative vaccine approach that provides broader protection against seasonal influenza.

24 Sep 2020

New data shows immunotherapy is beneficial for patients with gastric, esophageal cancers

New data presented at ESMO 2020 have shown that immunotherapy is beneficial for patients with gastric and esophageal cancers who currently have poor survival. (1-3)

24 Sep 2020

Study identifies genetic factors linked to higher risk of capecitabine-induced hand-foot syndrome

Capecitabine is a chemotherapy drug used for breast and colorectal Cancer cancer. It can extend survival rate by nearly 10%.

22 Sep 2020

Study shows how components of body's immune system find intruding cells

Research led by Dr. Wonmuk Hwang has led to a better understanding of how components of the body's immune system find intruding or damaged cells, which could lead to novel approaches to viral and cancer treatments.

17 Sep 2020

Inherited variation in GATA3 gene associated with relapse in children with leukemia

Scientists at St. Jude Children's Research Hospital are investigating the inherited genetics of childhood leukemia and how particular gene variations can affect treatment outcomes. The research showed that an inherited variation in the GATA3 gene strongly influences early response to chemotherapy and is linked to relapse in children with acute lymphoblastic leukemia (ALL).

14 Sep 2020

Researchers develop statistical model that predicts risk of developing esophageal cancer

Globally, esophageal cancer is said to be the eighth most common cancer and it usually develops from a condition known as Barrett’s esophagus.

9 Sep 2020

Honeybee venom rapidly destroys aggressive breast cancer cells

Using the venom from 312 honeybees and bumblebees in Perth Western Australia, Ireland and England, Dr Ciara Duffy from the Harry Perkins Institute of Medical Research and The University of Western Australia, tested the effect of the venom on the clinical subtypes of breast cancer, including triple-negative breast cancer, which has limited treatment options.

2 Sep 2020

Chemotherapy News and Research

Cell nucleus may enable the cells to evade crowded environments

New nanoparticles can destroy drug-resistant cancer cells

Treatment using immune system T cells preserves vision of mice with retinoblastoma

Immune cell biomarker may help identify patients at risk for graft-versus-host disease

New drug shows promise in the treatment of neuroblastoma

Genetic test identifies patients with invasive lobular carcinoma at high risk of recurrence

Researchers identify key molecules that contribute to radioresistance in glioblastoma

Scientists identify a novel approach to regulate cell plasticity

New precision drug targeting cancer's ability to repair DNA shows promise

T-cell-based vaccine strategy provides broader protection against influenza

New data shows immunotherapy is beneficial for patients with gastric, esophageal cancers

Study identifies genetic factors linked to higher risk of capecitabine-induced hand-foot syndrome

Study shows how components of body's immune system find intruding cells

Inherited variation in GATA3 gene associated with relapse in children with leukemia

Researchers develop statistical model that predicts risk of developing esophageal cancer

Honeybee venom rapidly destroys aggressive breast cancer cells

Natural killer cells could be a powerful weapon for fighting lung cancer

Researchers identify protein that causes adverse side effects in gastric cancer patients

DNA repair enzymes offer potential drug targets for personalized cancer therapies

New approach could slow colon cancer metastasis

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