Chemotherapy, in its most general sense, is the treatment of disease by chemicals especially by killing micro-organisms or cancerous cells. In popular usage, it refers to antineoplastic drugs used to treat cancer or the combination of these drugs into a cytotoxic standardized treatment regimen.
Researchers at The University of Texas MD Anderson Cancer Center have developed a new approach to quantify tumor-specific total mRNA levels from patient tumor samples, which contain both cancer and non-cancer cells.
Small interfering RNAs, or siRNAs, have the potential to cure tumors by targeting knocking down oncogenes that drive tumor development while avoiding the damage associated with chemotherapy.
Researchers at the University of Birmingham have identified a novel mechanism for cancer cells to repair DNA damage.
Many people believe tuberculosis (TB) is a disease of the past. Nonetheless, it claims over a million lives each year. Furthermore, the problem is escalating as Mycobacterium tuberculosis—the pathogen that causes tuberculosis develops resistance to the antibiotics used to treat the disease.
CAR T therapy, or chimeric antigen receptor T-cell therapy, has revolutionized the treatment of some blood cancers, allowing patients with relapsed or refractory disease to live longer and better lives.
Patients diagnosed with a type of brain tumor survived for longer when they were treated aggressively with surgery, radiation and chemotherapy.
Extra copies of a piece of DNA partly explain insensitivity to chemotherapy in germ cell cancer, a new study shows.
If genetics is concerned with gene sequencing, epigenetics is concerned with how genes are employed (or not) by a cell.
Combining a retrospective analysis of clinical records with in-depth laboratory studies, researchers at The University of Texas MD Anderson Cancer Center have discovered that vitamin E can enhance immunotherapy responses by stimulating the activity of dendritic cells in the tumor.
Ovarian cancer is a difficult to diagnose malignancy that is often caught at a more advanced stage. Treatments for this cancer have changed little over the past few decades, with surgery and chemotherapy being the most common therapeutic approaches.
After tumors are surgically removed, a novel biodegradable gel increases the immune system’s capacity to keep cancer away.
DNA is often likened to a blueprint. The particular sequence of As, Cs, Gs, and Ts in DNA provides information for building an organism.
The brain is composed of billions of neurons-; vulnerable cells that require a protective environment to function properly.
Human immune cells not only circulate in the blood, but can also occupy certain tissues and sometimes remain there for years.
Blocking a protein chain reaction makes childhood leukemia cells more sensitive to an existing targeted treatment, a new study shows.
The prognosis for ovarian cancer patients is grim: less than half of high-grade serous ovarian cancer (HGSC) patients survive past five years from diagnosis. Initially, the tumors typically respond well to chemotherapy but become resistant after repeated treatments, enabling the cancer to regrow.
A future vaccine providing protection against a wide range of coronaviruses that jump from their original animal hosts to humans -; including SARS-CoV-2, the cause of COVID-19 -; may be possible, say Johns Hopkins Medicine researchers, based on findings from their recent study.
Flow cytometry is a powerful and complex technology used to count, sort or measure characteristics of cells and to detect biomarkers.
We speak to Dr. Chao Ma, one of the speakers at SLAS 2022, about his groundbreaking 'leukemia-on-a-chip' technology and its future within therapy resistance.
Scientists have found a way to prove that biochemical signals sent from cell to cell play an important role in determining how those cells develop.