Chemotherapy News and Research

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Chemotherapy, in its most general sense, is the treatment of disease by chemicals especially by killing micro-organisms or cancerous cells. In popular usage, it refers to antineoplastic drugs used to treat cancer or the combination of these drugs into a cytotoxic standardized treatment regimen.

New technology efficiently detects gene mutation in blood with low error rate

Next-generation gene sequencing (NGS) technologies --in which millions of DNA molecules are simultaneously but individually analyzed-- theoretically provides researchers and clinicians the ability to noninvasively identify mutations in the blood stream.

5 May 2021

Study reveals a compound found in avocados helps in the treatment of leukemia

According to recent research at the University of Guelph, a compound found in avocados may one day lead to improved leukemia treatment.

4 May 2021

New therapeutic target for patients with acute myeloid leukemia

According to a new study, targeting a pathway that is critical for the survival of some cases of acute myeloid leukemia could open up a new therapeutic route for patients.

3 May 2021

Increased expression of DUSP16 molecule leads to cancer chemoresistance

Chemotherapy is a drug treatment that uses powerful chemicals to kill fast-growing cancer cells in the body. It is a systemic treatment where drugs travel throughout the body and destroy cancer cells that have spread (metastasized) to parts of the body far away from the original (primary) tumour.

28 Apr 2021

Therapy using artificial metalloenzymes helps reduce tumor growth, finds study

A new study has shown that it is viable to reduce tumor growth by a therapy that involves tagging cancer cells with various therapeutic molecules.

26 Apr 2021

Innovative technique encourages cancer cells in the kidneys to self-destruct

An innovative new technique that encourages cancer cells in the kidneys to self-destruct could revolutionize the treatment of the disease, a new study in the journal Pharmaceutics reports.

15 Apr 2021

Study shows that neural stem cells age quickly

A research team has revealed that neural stem cells (NSCs)—that is, the stem cells of the nervous system—age quickly.

14 Apr 2021

Researchers identify and test drug combination that exploits a weakness in small cell lung cancer

Researchers from the National Institutes of Health have identified and tested a drug combination that exploits a weakness in small cell lung cancer (SCLC), an aggressive, dangerous cancer.

13 Apr 2021

A new way to predict positive outcomes of immunotherapy in patients with bladder cancer

Researchers have detected and validated groups of genes linked to immunotherapy resistance in patients with metastatic urothelial cancer of the bladder.

12 Apr 2021

High expression of cell death genes linked to increased risk of dying early from lung cancer

Patients with a high number of genes most associated with pathways that lead to cell death in lung cancer are at increased risk of dying early from their disease, researchers report.

6 Apr 2021

Novel, non-invasive biomarker test could help measure, track performance of senolytics

Scientists from Buck Institute have identified and are now developing an innovative, non-invasive biomarker test that could help quantify and track the performance of senolytics—a class of drugs that selectively destroy senescent cells.

5 Apr 2021

Customized tumor cell vaccine produces active immune response in melanoma, neuroblastoma models

A pre-clinical study for melanoma and neuroblastoma shows that a customized tumor cell vaccine technique that targets Myc oncogenes coupled with checkpoint therapy produces an active immune response that bypasses antigen selection and immune privilege.

5 Apr 2021

Study identifies a pair of microRNA molecules that maintain the population of cancerous stem cells

A research team from Italy has discovered a pair of microRNA molecules that assist in maintaining a population of cancerous stem cells that fuel the growth of breast cancers and trigger tumor relapse after treatment.

5 Apr 2021

Researchers use mathematical modeling to explain CAR T-cell therapy dynamics

Chimeric antigen receptor T-cell therapy, or CAR T, is a relatively new type of therapy approved to treat several types of aggressive B cell leukemias and lymphomas.

26 Mar 2021

Genetically engineered immune cells deliver anticancer signal to organs to prevent metastasis

Scientists have genetically engineered immune cells, called myeloid cells, to precisely deliver an anticancer signal to organs where cancer may spread.

25 Mar 2021

Study maps structure, mechanism of membrane enzyme that has a role in chronic inflammation, cancer

A majority of the drugs work through the membranes surrounding the cells of the body.

22 Mar 2021

New technological approach to rapidly develop new drugs without animal experiments

A team of researchers led by Professor Yaakov Nahmias, director of the Grass Center for Bioengineering at the Hebrew University of Jerusalem and founder of Tissue Dynamic, introduced a new technological approach that has the potential to rapidly develop new drugs without the need for animal experiments.

10 Mar 2021

Regenerating bone marrow after chemotherapy

In this interview, AZoLifeSciences speaks to Professor Masaru Ishii about his latest research that investigated how bone marrow regenerates after chemotherapy.

10 Mar 2021

New substance could improve the treatment of drug-resistant cancers

A new substance could improve the treatment of persistent cancers. Researchers at Martin Luther University Halle-Wittenberg and the University of Greifswald have developed a new inhibitor that makes drug-resistant tumor cells respond again to chemotherapy.

9 Mar 2021

Study identifies molecular mechanism by which HSPCs recover after chemotherapy-induced injury

Chemotherapy has a damaging effect on hematopoietic stem and progenitor cells (HSPCs) in bone marrow. However, once chemotherapy ends, HSPCs regenerate, a process that has remained unknown--until now.

8 Mar 2021

Chemotherapy News and Research

New technology efficiently detects gene mutation in blood with low error rate

Study reveals a compound found in avocados helps in the treatment of leukemia

New therapeutic target for patients with acute myeloid leukemia

Increased expression of DUSP16 molecule leads to cancer chemoresistance

Therapy using artificial metalloenzymes helps reduce tumor growth, finds study

Innovative technique encourages cancer cells in the kidneys to self-destruct

Study shows that neural stem cells age quickly

Researchers identify and test drug combination that exploits a weakness in small cell lung cancer

A new way to predict positive outcomes of immunotherapy in patients with bladder cancer

High expression of cell death genes linked to increased risk of dying early from lung cancer

Novel, non-invasive biomarker test could help measure, track performance of senolytics

Customized tumor cell vaccine produces active immune response in melanoma, neuroblastoma models

Study identifies a pair of microRNA molecules that maintain the population of cancerous stem cells

Researchers use mathematical modeling to explain CAR T-cell therapy dynamics

Genetically engineered immune cells deliver anticancer signal to organs to prevent metastasis

Study maps structure, mechanism of membrane enzyme that has a role in chronic inflammation, cancer

New technological approach to rapidly develop new drugs without animal experiments

Regenerating bone marrow after chemotherapy

New substance could improve the treatment of drug-resistant cancers

Study identifies molecular mechanism by which HSPCs recover after chemotherapy-induced injury

Developing a portable tool to detect street drug ‘spice’

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