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Experts Unravel the Crystal Structure of CENP-E

Anticancer drugs are essential in cancer treatment, but their toxicity is not always restricted to cancer cells, resulting in serious side effects.

5 Apr 2023

Astrocytes Pull the Handbrake to Drive the Brain to a More Relaxed State

A brimming inbox on Monday morning sets your head spinning. You take a moment to breathe and your mind clears enough to survey the emails one by one.

5 Apr 2023

Novel Genes Could Serve as Predictive Biomarkers for PARP Inhibitor Response in Prostate Cancer

Prostate cancer tumors harboring BRCA1/2 mutations are exceptionally sensitive to PARP inhibitors, while genomic alterations in other DNA damage response (DDR) genes are less responsive.

5 Apr 2023

Potential Treatment Pathway for IBD Emerges from Microbe-Gut Signaling Study

Fresh insights into how our bodies interact with the microbes living in our guts suggest that a two-drug combination may offer a new way to treat inflammatory bowel diseases such as Crohn's disease and ulcerative colitis.

4 Apr 2023

Using Purified Curcumin to Create Probiotic Yogurt that Contains No Artificial Preservatives

Researchers have succeeded for the first time in adding a highly purified form of curcumin to yogurt in a way that ensures it remains dissolved in the dairy product and preserves it, while tasting good.

4 Apr 2023

Jumping Genes in Various Cancers may be Used to Direct Novel Immunotherapies to Tumors

New research from Washington University School of Medicine in St. Louis suggests that transposable elements in various cancers potentially may be used to harness novel immunotherapies against tumors that don't typically respond to immune-based treatments. Shown is a 3D rendering of cancer cells.

4 Apr 2023

Designing a Lipid Nanoparticle to Safely Deliver mRNA to the Pancreas

Therapeutics that use mRNA-;like some of the COVID-19 vaccines-;have enormous potential for the prevention and treatment of many diseases.

4 Apr 2023

Newly Identified Rare Genetic Variants Could Point to One of the General Mechanisms Driving AMD

A study from the National Eye Institute (NEI) identified rare genetic variants that could point to one of the general mechanisms driving age-related macular degeneration (AMD), a common cause of vision loss in older adults.

3 Apr 2023

Newly developed toolkit uses small molecules to control the activity of synthetic RNA

The Okinawa Institute of Science and Technology, in collaboration with Astellas Pharma Inc., has developed a new toolkit that uses small molecules to control the activity of a piece of synthetic RNA, and ultimately regulate gene expression.

31 Mar 2023

Maternal vaginal microbiome does not substantially influence the infant stool microbiome

It has been a longstanding assumption that birth mode and associated exposure of newborns to their mothers' vaginal microbiome during delivery greatly affects the development of babies' gut microbiome.

31 Mar 2023

New nanoparticles can deliver mRNA encoding CRISPR/Cas9 components to the lungs

Engineers at MIT and the University of Massachusetts Medical School have designed a new type of nanoparticle that can be administered to the lungs, where it can deliver messenger RNA encoding useful proteins.

31 Mar 2023

Immune cells in human blood produce acetylcholine that regulates blood pressure and inflammation

Acetylcholine regulates blood flow, but the source of blood acetylcholine has been unclear. Now, researchers at Karolinska Institutet have discovered that certain T cells in human blood can produce acetylcholine, which may help regulate blood pressure and inflammation.

31 Mar 2023

Clearance of senescent cells by boosting anti-viral immune response

Aging, or senescent cells, which stop dividing but don't die, can accumulate in the body over the years and fuel chronic inflammation that contributes to conditions such as cancer and degenerative disorders.

31 Mar 2023

Neutrophils can affect the success of immunotherapy in treating cancer, study shows

Cancer immunotherapies that recruit a patient's own immune system to destroy tumors have transformed the treatment of many types of cancer. Yet these therapies do not elicit universally good treatment responses.

31 Mar 2023

BGI Genomics and Zentya collaborate to launch COLOTECT in Slovakia

BGI Genomics is pleased to announce the launch of COLOTECTTM 1.0 in Slovakia, in collaboration with its local partner, Zentya. Zentya is a Slovak-based healthcare solution provider that is passionate about providing patients with the latest technology in the field of genetic screening, aiming to help identify and facilitate timely treatments of genetic diseases.

31 Mar 2023

Harnessing a natural bacterial system to deliver proteins in mice and human cells

Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have harnessed a natural bacterial system to develop a new protein delivery approach that works in human cells and animals.

30 Mar 2023

Single monoclonal antibody infusion can strengthen the body's fight against yellow fever

New research from Oregon Health & Science University and collaborators indicates lab-made antibodies may be able to cure people infected with yellow fever, a virus for which there is no treatment.

30 Mar 2023

COVID-19 vaccines boost the levels of T cells in immunocompromised hematology patients

Researchers found that, despite being heavily immunocompromised, hematology patients generate strong cellular immune responses against SARS-CoV-2 after vaccination, on par with that of healthy individuals.

30 Mar 2023

FDA-approved compound promotes photoreceptor survival in lab models of inherited retinal ciliopathy

A National Eye Institute-led team has identified a compound already approved by the U.S. Food and Drug Administration that keeps light-sensitive photoreceptors alive in three models of Leber congenital amaurosis type 10 (LCA 10), an inherited retinal ciliopathy disease that often results in severe visual impairment or blindness in early childhood.

30 Mar 2023

Study reports a new target to fight against antibiotic-resistant pneumonia

Increases in multidrug-resistance in the bacteria Streptococcus pneumoniae have made it the fourth-leading cause of death associated with antibiotic resistance.

30 Mar 2023

Clinical News and Research

Experts Unravel the Crystal Structure of CENP-E

Astrocytes Pull the Handbrake to Drive the Brain to a More Relaxed State

Novel Genes Could Serve as Predictive Biomarkers for PARP Inhibitor Response in Prostate Cancer

Potential Treatment Pathway for IBD Emerges from Microbe-Gut Signaling Study

Using Purified Curcumin to Create Probiotic Yogurt that Contains No Artificial Preservatives

Jumping Genes in Various Cancers may be Used to Direct Novel Immunotherapies to Tumors

Designing a Lipid Nanoparticle to Safely Deliver mRNA to the Pancreas

Newly Identified Rare Genetic Variants Could Point to One of the General Mechanisms Driving AMD

Newly developed toolkit uses small molecules to control the activity of synthetic RNA

Maternal vaginal microbiome does not substantially influence the infant stool microbiome

New nanoparticles can deliver mRNA encoding CRISPR/Cas9 components to the lungs

Immune cells in human blood produce acetylcholine that regulates blood pressure and inflammation

Clearance of senescent cells by boosting anti-viral immune response

Neutrophils can affect the success of immunotherapy in treating cancer, study shows

BGI Genomics and Zentya collaborate to launch COLOTECT in Slovakia

Harnessing a natural bacterial system to deliver proteins in mice and human cells

Single monoclonal antibody infusion can strengthen the body's fight against yellow fever

COVID-19 vaccines boost the levels of T cells in immunocompromised hematology patients

FDA-approved compound promotes photoreceptor survival in lab models of inherited retinal ciliopathy

Study reports a new target to fight against antibiotic-resistant pneumonia

Expert Insights: HiMedia Labs on Advancing Nucleic Acid Extraction Across Industries

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

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