Colorectal News and Research

RSS

Gut Microbiota Signatures Linked to KRAS Mutations in Colorectal Cancer Patients

For about 40% of people diagnosed with colorectal cancer (CRC), the tumor carries a mutation in a gene called KRAS. Many of those mutations have been linked to shorter survival and more aggressive forms of disease.

5 Apr 2024

Machine Learning Reveals Cancer-Causing DNA Repeats

It has been difficult to identify and characterize repeats of DNA sequences, also known as “junk DNA” or “dark matter,” that are found in chromosomes and may be involved in cancer or other diseases.

14 Mar 2024

'lncREST' RNA Unveiled as Key Player in DNA Replication Stress Response

Researchers at Cima Universidad de Navarra have discovered that a ribonucleic acid that does not contain information to make proteins (long non-coding RNA) plays a crucial role in signalling and repairing errors in DNA replication during cell division.

5 Mar 2024

SOX17 Gene Identified as Critical for Immune Evasion in Early-Stage Colon Cancer

One of the immune system's primary roles is to detect and kill cells that have acquired cancerous mutations.

29 Feb 2024

Unveiling the Design Principles of Gene Regulatory Networks

Over the last 20 years, researchers in biology and medicine have created Boolean network models to simulate complex systems and find solutions, including new treatments for colorectal cancer.

24 Jan 2024

AI Program Reveals Cellular Neighborhoods in Cancer Microenvironments

A novel AI-powered program has been developed by researchers at Children's Hospital of Philadelphia (CHOP) to assist in comprehending how various cells arrange themselves into certain tissues and communicate with one another.

9 Jan 2024

AI Tool Offers a Deep Dive Into Tissues, Boosting Cancer Detection and Treatment

A new artificial intelligence tool that interprets medical images with unprecedented clarity does so in a way that could allow time-strapped clinicians to dedicate their attention to critical aspects of disease diagnosis and image interpretation.

3 Jan 2024

Study Identifies Risk Genes and Regulatory Variants for Colorectal Cancer by Integrating Multi-Omics Data

This study was led by Prof. Xiao-Ping Miao' team from the School of Public Health, Wuhan University, in collaboration with Prof. Shaokai Zhang from the Henan Cancer Hospital.

2 Nov 2023

Regulator Gene for Intestinal Stem Cells Discovered

When a cell dies, a new one has to be formed in its place. This is a regular occurrence in the intestines, where cells are especially exposed to harmful effects.

9 Oct 2023

Key Proteins in Human Breast Milk Crucial for Baby’s Healthy Gut

The abundance of two species of bacteria known to be good for human health and used as probiotics, Clostridium butyricum and Parabacteroides distasonis, has been linked to high concentrations of key proteins in human breast milk, particularly osteopontin and κ-casein.

13 Sep 2023

Mainz Biomed Announces Live Launch of ColoAlert® with Marylebone Laboratory in the United Kingdom

Mainz Biomed NV (“Mainz Biomed” or the “Company”), a molecular genetics diagnostic company specializing in the early detection of cancer, announced today that London-based Marylebone Laboratory (Marylebone Lab Ltd) has introduced ColoAlert®, Mainz Biomed’s flagship product—a highly effective and user-friendly at-home detection test for colorectal cancer (CRC) - to its extensive UK and international customer base.

2 Aug 2023

Analyzing DNA Damage-Induced NF-κB Targeted by Novel Small Molecule Inhibitors

Chemotherapy and radiotherapy aim to destroy cancer cells by inducing DNA double-strand breaks – damage that, once inflicted, usually causes the cells to die. But damage to a cell's genetic material also activates a signaling pathway called IKK/NF-κB that helps prevent cell death, thus limiting the success of these treatments in patients.

28 Jul 2023

New Method Facilitates Early Detection and Localization of Tumors

To help with early tumor diagnosis and tumor localization, researchers have devised a technology that concurrently detects many cancer-specific DNA circulating hallmarks.

26 Jul 2023

Study Reveals Key Insights Into the Evolution of Tumor Microenvironment in Gastric Cancer

A new study led by researchers at The University of Texas MD Anderson Cancer Center provides a deeper understanding of the evolution of the tumor microenvironment during gastric cancer progression.

7 Jul 2023

New Nanoparticle Developed Helps Improve the Delivery of mRNA-Based Vaccines

Johns Hopkins Medicine scientists say they have developed a nanoparticle -; an extremely tiny biodegradable container -; that has the potential to improve the delivery of messenger ribonucleic acid (mRNA)-based vaccines for infectious diseases such as COVID-19, and vaccines for treating non-infectious diseases including cancer.

29 Jun 2023

Colorectal News and Research

Gut Microbiota Signatures Linked to KRAS Mutations in Colorectal Cancer Patients

Machine Learning Reveals Cancer-Causing DNA Repeats

'lncREST' RNA Unveiled as Key Player in DNA Replication Stress Response

SOX17 Gene Identified as Critical for Immune Evasion in Early-Stage Colon Cancer

Unveiling the Design Principles of Gene Regulatory Networks

AI Program Reveals Cellular Neighborhoods in Cancer Microenvironments

AI Tool Offers a Deep Dive Into Tissues, Boosting Cancer Detection and Treatment

Study Identifies Risk Genes and Regulatory Variants for Colorectal Cancer by Integrating Multi-Omics Data

Regulator Gene for Intestinal Stem Cells Discovered

Key Proteins in Human Breast Milk Crucial for Baby’s Healthy Gut

Mainz Biomed Announces Live Launch of ColoAlert® with Marylebone Laboratory in the United Kingdom

Analyzing DNA Damage-Induced NF-κB Targeted by Novel Small Molecule Inhibitors

New Method Facilitates Early Detection and Localization of Tumors

Study Reveals Key Insights Into the Evolution of Tumor Microenvironment in Gastric Cancer

New Nanoparticle Developed Helps Improve the Delivery of mRNA-Based Vaccines

Discovering a Major Factor Causing Aggressive Cancer

Pancreatic Cancer Cells Use a New Nutrient Source to Grow, Study Finds

Fecal Microbiota Transplantation to Help in Clostridioides difficile Infection

Understanding How Cell-to-Cell Communication Networks Drive Pancreatic Cancer Development

Patient-Derived Organoids can Help Identify Effective Personalized Cancer Therapies

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Commercializing Innovation in a Life Sciences Ecosystem

Latest in Genomics