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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Study Suggests a Link Between DNA Methylation Disorder and Epigenetic Clocks

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 2, entitled, "Epigenetic drift underlies epigenetic clock signals, but displays distinct responses to lifespan interventions, development, and cellular dedifferentiation."

7 Feb 2024

Outsmarting Viruses: Scientists Rewire Bacteria for Biomanufacturing Revolution

Genome engineering allows scientists to modify the genetic code of microbes. Now, researchers have engineered the genome of the bacterium Escherichia coli (E. coli) to make it immune to viral infections.

6 Feb 2024

Enhanc3D Genomics Appoints Dr Daniel Turner as Chief Scientific Officer

Enhanc3D Genomics, a company developing disruptive technologies to unlock the 3D spatial genome for target and biomarker discovery, today announced the appointment of Dr Daniel Turner as Chief Scientific Officer (CSO). Dan’s deep expertise in genomics technology development and commercialisation will be key to achieving the next phase of Enhanc3D Genomics’ growth.

1 Feb 2024

Tomatoes as Nature's Antibacterial Agents

According to research published in Microbiology Spectrum, a magazine of the American Society for Microbiology, tomato juice can eliminate Salmonella Typhi and other bacteria that can damage people's digestive and urinary system health. Typhoid fever is brought on by the lethal human-specific bacterium Salmonella Typhi.

31 Jan 2024

RNA-Seq Unveils Molecular Subtypes for Tailored Pediatric B-ALL Treatment

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, representing more than 30% of all pediatric cases.

31 Jan 2024

Scientists Create "Immunologically Silent" DNA Vaccine for Potent Virus Defense

Using a virus-like delivery particle made from DNA, researchers from MIT and the Ragon Institute of MGH, MIT, and Harvard have created a vaccine that can induce a strong antibody response against SARS-CoV-2.

31 Jan 2024

Formulatrix® and Olink® Announce Collaboration to Deliver Automated Proteomics Research Solutions to Enable Protein Detection with Exceptional Precision and Speed

Formulatrix, a leader in innovative automated liquid handling technologies, announced a multi-year collaboration and supply agreement to advance the automation of Olink’s PEA (Proximity Extension Assay) technology, including the Target 96, Target 48, Flex, and Explore workflows.

From FORMULATRIX 31 Jan 2024

NLRC5 Gene Reactivation Boosts Tumor-Killing Immunity

Every human cell has class I major histocompatibility complex (MHC) molecules on its surface, which are immune complexes. The immune system needs MHC class I molecules to identify and eradicate cancer.

30 Jan 2024

51 Vertebrate Genomes Sequenced Rapidly, Offering a New Perspective on Human Evolutionary History

The mapping of genetic blueprints for 51 species, such as sharks, turtles, kangaroos, cats, penguins, and dolphins, has advanced the knowledge of evolution and the relationships between animals and people.

30 Jan 2024

Chemists Develop Two-Step Method to Create Promising Molecules for Life Sciences Research

Organic compounds in the field of chemistry range from simple hydrocarbons to complex molecules, with diverse functional groups added to the main carbon backbone.

30 Jan 2024

Asimov Launches LV Edge Packaging System to Optimize Lentivirus Production

Asimov, the synthetic biology company advancing the design and manufacture of therapeutics, today announced the launch of their LV Edge Packaging System, which improves the cost efficiency and reduces the supply chain risk of lentiviral production.

30 Jan 2024

New Horizons in Chemical Biology: A Novel Approach to Synthesize Dibenzothiophene S-Oxides

Dibenzothiophene S-oxides are important in various biochemical processes. However, their synthesis using conventional methods is not easy.

30 Jan 2024

Promoter Mutations and Their Association with Autism Risk

The RIKEN Center for Brain Science (CBS) employed genome mutation analysis to investigate the genetics of autism spectrum disorder (ASD) in people and their families. They found that the way a certain type of genetic mutation contributes to the illness differs from that of ordinary mutations.

29 Jan 2024

ISS National Lab-Sponsored Investigation Aims to Expand Genes in Space™ Toolkit on Station

For nearly a decade, Genes in Space™ has challenged students to develop spaceflight experiments that use biotechnology to address spaceflight challenges.

27 Jan 2024

High-Resolution Map Exposes Cellular Pathways to Fertility

An interdisciplinary team mapped the gene expression that takes place in mice during follicle maturation and ovulation using a state-of-the-art method of RNA tagging.

24 Jan 2024

Unveiling the Design Principles of Gene Regulatory Networks

Over the last 20 years, researchers in biology and medicine have created Boolean network models to simulate complex systems and find solutions, including new treatments for colorectal cancer.

24 Jan 2024

New Insights Into How Genetic Variation Affects Gene Expression

Chromatin accessibility and transcription factor binding are determined by genetic variation, according to a recent study from the University of Eastern Finland.

23 Jan 2024

RNAs on the Cell Surface Regulate Neutrophil Recruitment

In recent times, scientists have encountered RNAs venturing beyond their traditional cellular domains. A study conducted at Yale provides valuable insights into their activities in these unconventional locations.

23 Jan 2024

Genomic Insights Into the Evolution of Gigantism in Cetaceans

Certain gene regions in cetaceans (whales, porpoises, and dolphins) play a role in explaining the remarkable size differences among species, such as the Blue whale (Balaenoptera musculus), which can reach lengths of up to 30 m – almost 10 m longer than a bus – in contrast to the Bottlenose dolphin (Tursiops truncatus), which typically reaches a maximum length of 4 m.

23 Jan 2024

Phage Proteins Tame CRISPR-Cas3, Paving Way for Precise Gene Therapy

Through the use of CRISPR, an immune system that bacteria use to defend themselves against viruses, researchers have been able to alter genetic information within cells.

22 Jan 2024