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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Unraveling the Complexities of X Chromosome Inheritance

A new study published in Nature Genetics by the Lymphoid Development Group at the MRC Laboratory of Medical Sciences has reveals that the contribution of cells expressing maternal or paternal X chromosomes can be selectively skewed in different parts of the body.

26 Jul 2024

Cost-Effective Array Sheds Light on Imprinted Gene Regulation

Researchers from North Carolina State University have developed an array that assesses methylation levels of genes located in imprint control regions (ICRs) within the human genome. The array represents a cost-effective, efficient method for exploring potential links between environmental exposures and epigenetic dysregulation during the early developmental origins of diseases and behavioral disorders.

26 Jul 2024

New Insights into the Mechanisms of Gene Misbehavior

Researchers have discovered that a startlingly widespread occurrence in the healthy human population is "gene misbehavior," or the state in which genes are active when they should be inactive.

25 Jul 2024

DNA Sequence Variants Drive Link Between Methylation and Gene Expression

The relationship between DNA methylation and gene expression is driven by sequence variants, according to a recent study conducted by researchers at deCODE Genetics, an Amgen subsidiary.

25 Jul 2024

NanoRanger Offers Rapid, Precise Diagnosis for Genetic Diseases

An effective long-read sequencing method that looks for intricate genomic variations can quickly and accurately diagnose genetic disorders molecularly.

24 Jul 2024

Macrolones Offer Promising Strategy for Combating Resistant Bacteria

New research from the University of Illinois Chicago suggests that a novel antibiotic that disrupts two distinct cellular targets would make it 100 million times harder for bacteria to evolve resistance.

24 Jul 2024

New Assay Fast-Tracks Virucidal Testing

An innovative technique that can quickly ascertain whether a virus is contagious or not has the potential to completely transform how humans respond to pandemics in the future.

24 Jul 2024

New RNA Sequencing Dataset Reveals Genetic Diversity Across Global Populations

An open-access dataset of RNA sequences from lymphoblastoid cell lines of 731 individuals spanning 26 populations and five continental groups.

24 Jul 2024

Developing DNA Test to Eliminate Inherited Blindness in English Shepherd Dogs

Researchers at Cambridge have discovered the genetic mutation that causes English Shepherd Dogs to suffer from progressive retinal atrophy, an irreversible form of blindness.

22 Jul 2024

How Tiny Freshwater Animals Utilize Bacterial DNA to Fight Fungal Infections

A group of small, freshwater animals protect themselves from infections using antibiotic recipes "stolen" from bacteria, according to new research by a team from the University of Oxford, the University of Stirling and the Marine Biological Laboratory (MBL), Woods Hole.

19 Jul 2024

Global Gene Expression Data Improves Precision in Genetics

The majority of human genetics research has traditionally concentrated on individuals with European ancestry, a long-standing bias that may reduce the precision of scientific predictions for individuals from other populations.

18 Jul 2024

ENGRAM: Capturing Cellular Histories Through Genomic Recording

Genomes can now be entrusted to store information about a variety of transient biological events inside of living cells, as they happen, like a flight recorder collecting data from an aircraft.

18 Jul 2024

Reawakened Endogenous Retroviruses can Play a Critical Role in Helping Cancer Survive

Peek inside the human genome and, among the 20,000 or so genes that serve as building blocks of life, you'll also find flecks of DNA left behind by viruses that infected primate ancestors tens of millions of years ago.

18 Jul 2024

Fossils in Our Genes: Giant Viruses Leave Mark on Animal Relative

Recent research published in Science Advances uncovers an unexpected twist in the evolutionary history of complex life.

17 Jul 2024

PUMA: A Breakthrough in CRISPR-Cas12 for RNA Biomarker Detection

CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics.

17 Jul 2024

Nitrogen-Fixing Nodules Evolved More Than Once in Plants

Feeding the world's expanding population is made possible by nitrogen fertilizers, but their production is energy-intensive, expensive, and detrimental to ecosystems.

16 Jul 2024

Neuregulin 3 Gene Variant Linked to Gabapentin Effectiveness in Chronic Pelvic Pain

Women who carry a particular form of a pain gene are more likely to respond well to a common medication used to treat long-term discomfort, research shows.

16 Jul 2024

Earliest Ancestors of Life Explored in Latest Scientific Study

A digital representation illustrating how LUCA was already under attack from viruses even at 4.2 billion years ago. Image Credit: Science Graphic Design

15 Jul 2024

All-RNA Gene Writing Method Paves Way for Precise Gene Editing in Human Cells

A novel gene-writing technology based on retrotransposons.

15 Jul 2024

Harnessing Enzymes for Making RNA Therapeutics

While the COVID-19 vaccines introduced many people to RNA-based medicines, RNA oligonucleotides have already been on the market for years to treat diseases like Duchenne Muscular Dystrophy and amyloidosis.

15 Jul 2024