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Research explains how E4 peptide exerts antifibrotic effect and what makes it so effective

A research team at the Medical University of South Carolina led by Carol Feghali-Bostwick, Ph.D., reports in the Journal of Clinical Investigation Insight that the E4 peptide reverses fibrosis, or scarring, in human and mouse tissues by activating an antifibrotic pathway that is common to all organ systems.

11 Jan 2022

Scientists use fruit fly embryos to study immune cell invasion

To fight infections and heal injuries, immune cells need to enter tissue. They also need to invade tumors to fight them from within.

7 Jan 2022

Severe lung injuries can trigger stem cells to undergo abnormal differentiation, study finds

Severe injuries to the lung from diseases such as COVID-19 trigger abnormal stem cell repair that alters the architecture of the lung. The aberrant stem cell differentiation in response to injury can prevent the restoration of normal lung function.

31 Dec 2021

Researchers grow intestinal organoids to study why bats infected with viruses do not succumb to diseases

Experiments attempting to explain why bats can be infected with many viruses at a time without succumbing to diseases such as COVID-19-;knowledge that could help us to reduce the threat to humans of infectious disease-;have struggled until now with the fact that live wild bats make poor research subjects.

30 Dec 2021

People with inflammatory bowel disease have more fecal microplastics

Microplastics -; tiny pieces of plastic less than 5 mm in length –– are everywhere, from bottled water to food to air. According to recent estimates, people consume tens of thousands of these particles each year, with unknown health consequences.

23 Dec 2021

How Can Sustainable Agricultural Practices Improve Soil Health?

In this interview, we speak to Dr. Fiona Brennan from Teagasc, about the importance of sustainable agricultural practices and how they can help to improve soil health.

21 Dec 2021

Researchers develop new method to detect the onset of blood damage at sublethal stage

Red blood cells (RBCs) or erythrocytes are constantly exposed to a "shearing stress" during their circulation in the body. This stress is usually mild and the RBCs are flexible enough to accommodate shape changes in response to it.

17 Dec 2021

Menu composition must be 75% vegetarian to encourage sustainable plant-based food choices

Researchers from the University of Westminster have found that meat eaters are significantly more likely to choose vegetarian meals when they make up the majority of food offered. A menu had to be at least 75% vegetarian for this choice tipping point to occur.

15 Dec 2021

A missing link explains how class I molecules evolved from a class II-like origin Major Histocompatibility...

Which came first, MHC class I or MHC class II? For decades, it has been debated which of these two similar classes came first in evolution. Now, Keiichiro Hashimoto and his group at Fujita Health University, Japan, in collaboration with European research groups, have provided an answer to this question in a new article in PNAS.

14 Dec 2021

Scientists find how cells remain dormant for years before awakening to create metastatic cancer

Mount Sinai researchers have solved a major mystery in cancer research: How cancer cells remain dormant for years after they leave a tumor and travel to other parts of the body, before awakening to create metastatic cancer.

14 Dec 2021

Study suggests dietary intake of flavan-3-ols could help prevent obesity

In cold conditions, brown adipose tissue (BAT) or brown fat generates heat to keep the body warm. Compared with white adipose tissue, BAT has more mitochondria-;subcellular organelles associated with energy production-;which allows it to burn calories and produce heat by activating the mitochondrial uncoupling protein 1 (Ucp-1).

14 Dec 2021

Infant's immune system may be better than the adult immune system

As any parent knows, infants are prone to getting respiratory infections. But a new study shows that the infant immune system is stronger than most people think and beats the adult immune system at fighting off new pathogens.

13 Dec 2021

Research describes dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Clinician scientists and scientists from the National Cancer Centre Singapore and A*STAR's Genome Institute of Singapore, in collaboration with Singapore General Hospital, the National University Health System, Duke-NUS Medical School, Nanyang Technological University, and collaborators from China, Malaysia, Thailand and the Philippines, have described a dynamic genomic landscape of tumour heterogeneity in hepatocellular carcinoma (HCC).

13 Dec 2021

Battery-free, wearable device could quantify airborne nicotine exposure from e-cigarettes

Some studies have shown that nicotine, an addictive substance in electronic cigarettes, increases the risk of cardiovascular and respiratory disorders.

10 Dec 2021

Using plant-based ingredients to 3D-print meat alternatives

No longer just a dream of vegetarians and vegans, fake meat is becoming more widely available in grocery stores and restaurants. And more options are almost certainly on the way.

9 Dec 2021

People previously infected by Chikungunya virus may develop partial immunity to Mayaro virus

A study conducted at the University of São Paulo (USP) in Brazil suggests people previously infected by Chikungunya virus may develop partial immunity to Mayaro virus.

6 Dec 2021

Growing healthy, nutritious food with a minimized carbon and water footprint

Before pandemic-era panic buying strained food supply chains and emptied grocery store shelves, the United States food system was already in need of sustainable food production improvements.

1 Dec 2021

UAB expert shares the science of how to make a delicious Thanksgiving meal

Thanksgiving is a time when many Americans pull out their boxes of recipes from generations of family members, but one thing that may not be included in your grandmother's turkey stuffing -; or dressing -; recipe is what happens at a molecular level to make it worth gobbling up.

29 Nov 2021

Research could help understand DCIR's role in the pathogenesis of autoimmune diseases

While dendritic cell immunoreceptor (DCIR) is known to mediate inflammation and bone metabolism, ligands that bind DCIR and the mechanisms underlying DCIR activity remain poorly understood.

From Tokyo University of Science 25 Nov 2021

Study shows why disruption of the body clock leads to inflammatory diseases

New research from RCSI has demonstrated the significant role that an irregular body clock plays in driving inflammation in the body's immune cells, with implications for the most serious and prevalent diseases in humans.

25 Nov 2021

Education News and Research

Research explains how E4 peptide exerts antifibrotic effect and what makes it so effective

Scientists use fruit fly embryos to study immune cell invasion

Severe lung injuries can trigger stem cells to undergo abnormal differentiation, study finds

Researchers grow intestinal organoids to study why bats infected with viruses do not succumb to diseases

People with inflammatory bowel disease have more fecal microplastics

How Can Sustainable Agricultural Practices Improve Soil Health?

Researchers develop new method to detect the onset of blood damage at sublethal stage

Menu composition must be 75% vegetarian to encourage sustainable plant-based food choices

A missing link explains how class I molecules evolved from a class II-like origin Major Histocompatibility...

Scientists find how cells remain dormant for years before awakening to create metastatic cancer

Study suggests dietary intake of flavan-3-ols could help prevent obesity

Infant's immune system may be better than the adult immune system

Research describes dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Battery-free, wearable device could quantify airborne nicotine exposure from e-cigarettes

Using plant-based ingredients to 3D-print meat alternatives

People previously infected by Chikungunya virus may develop partial immunity to Mayaro virus

Growing healthy, nutritious food with a minimized carbon and water footprint

UAB expert shares the science of how to make a delicious Thanksgiving meal

Research could help understand DCIR's role in the pathogenesis of autoimmune diseases

Study shows why disruption of the body clock leads to inflammatory diseases

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