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New Tool Reveals RNA Locations Inside Cells With Nanoscale Precision

A new tool called PHOTON, developed by scientists at UT Southwestern Medical Center, can identify RNA molecules at their native locations within cells – providing valuable clues to where different RNA species are distributed spatially in response to various cellular cues.

30 Jun 2025

Yeast Model Offers Insight Into Proteasome and Mitochondria Interplay

A study by the Center for Redox Processes in Biomedicine (Redoxoma) led by Marilene Demasi from the Butantan Institute (São Paulo, Brazil) presents a valuable new experimental model for investigating the interaction between the proteasome and mitochondrial function.

30 Jun 2025

Study Finds Protein Cleavage Essential for Healthy Cilia and Cell Signaling

New research by Sumeda Nandadasa, PhD, reveals how a key protein associated with Meckel-Gruber syndrome, nephronophthisis, Joubert syndrome and other ciliopathies is cut in half to perform two separate functions, both of which are fundamental to the healthy development of children.

30 Jun 2025

Worm Species Reveal Deep Genetic Similarities Across Evolutionary Time

Two species of worms, separated by 20 million years of evolution, have been found to activate their genes in nearly identical ways as they develop from a single cell to a fully formed organism.

27 Jun 2025

Gene Editing Halts Symptoms of Rare Smooth Muscle Disease in Preclinical Study

Using gene editing in a preclinical model, researchers at UT Southwestern Medical Center blocked the symptoms of a rare smooth muscle disease before they developed.

25 Jun 2025

UT Southwestern Researchers Develop Multi-Organ Gene Editing Strategy

A gene-editing delivery system developed by UT Southwestern Medical Center researchers simultaneously targeted the liver and lungs of a preclinical model of a rare genetic disease known as alpha-1 antitrypsin deficiency (AATD), significantly improving symptoms for months after a single treatment, a new study shows.

23 Jun 2025

Hippocampal Neurons Show Surprising Flexibility in Brain Signal Processing

The brain is constantly mapping the external world like a GPS, even when we don't know about it. This activity comes in the form of tiny electrical signals sents between neurons -- specialized cells that communicate with one another to help us think, move, remember and feel.

17 Jun 2025

Myosin XI Helps Plants Absorb Boron Under Nutrient Stress

Boron, though required only in minimal amounts, is vital for plant development. It strengthens cell walls and supports the growth of roots and shoots.

9 Jun 2025

Ochsner Health Shares Blueprint for Integrating Pharmacogenomics into Clinical Practice

In a report recently published in the American Journal of Health-System Pharmacy, the Ochsner Health system delves into the multifaceted implementation of pharmacogenomics-a rapidly evolving field that examines how genetics influence individual responses to medication.

5 Jun 2025

Blocking Viral Enzyme Boosts Brain Immunity Against HSV-1

Infections caused by herpes simplex virus type 1 (HSV-1) can lead to HSV-1 encephalitis-a rare but deadly condition that inflames the brain.

4 Jun 2025

Study Reveals Key Proteins Behind CAR-T Cell Therapy Effectiveness

A study conducted by researchers at the Center for Cell-Based Therapy (CTC) highlights key proteins and signaling pathways involved in the efficacy of immunotherapy based on CAR-T cells (lymphocytes modified in the laboratory to fight cancer).

4 Jun 2025

Drought-Fighting Soil Bacteria Helping Wheat Beat the Heat

Western Sydney University researchers have discovered that drought affected wheat plants are able to call on eco-friendly soil bacteria to survive, helping keep crops healthy, boost yields, and provide pathways to develop extreme weather resistant crops.

30 May 2025

RNA Editing and Transcriptional Switching Shape Fungal Antiviral Response

The expression of symptoms of viral infections is a byproduct of complex virus-host molecular pathways. These remain largely unknown, especially in the case of fungus-virus pathogen systems.

24 May 2025

Scientists Engineer Proteins That Morph Like Nature’s Own

The ability to engineer shapeshifting proteins opens new avenues for medicine, agriculture, and beyond.

24 May 2025

New Genomic Score Predicts Risk of Progression in Multiple Myeloma

A new risk assessment score developed by researchers at Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard reveals how multiple myeloma, a form of blood cancer, begins and progresses from precancerous to malignant states by tracing DNA mutations.

24 May 2025

Gene Loss and Gain Shaped the Evolution of Relapsing Fever Bacteria

Researchers at the Francis Crick Institute and UCL have analyzed ancient DNA from Borrelia recurrentis, a type of bacteria that causes relapsing fever, pinpointing when it evolved to spread through lice rather than ticks, and how it gained and lost genes in the process.

24 May 2025