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Study identifies genetic mutation in the SPTSSA gene as cause of Hereditary Spastic Paraplegia

A genetic mutation in the SPTSSA gene is identified as the cause of Hereditary Spastic Paraplegia, a rare disease that causes progressive weakness, stiffness and spasticity in the lower extremities, according to a study, "SPTSSA variants alter sphingolipid synthesis and cause a complex hereditary spastic paraplegia," published in Brain on on Jan. 30.

1 Feb 2023

Genomic study helps retrace origin and spread of Shigellosis outbreak in Seattle

A genomic study of a sustained, multidrug-resistant Shigellosis outbreak in Seattle enabled scientists to retrace its origin and spread.

1 Feb 2023

Research supports the safety and efficacy of COVID-19 vaccination in cancer patients receiving immunotherapy

Research findings published in Frontiers in Immunology show that cancer immunotherapy does not interfere with COVID-19 immunity in previously vaccinated patients.

1 Feb 2023

Study findings may pave way for personalized cancer treatment

In a step likely to advance personalized cancer treatment, scientists have for the first time shown in patients that levels of biomarkers are not enough to tell which patients are likely to respond best to immunotherapy.

31 Jan 2023

Phase II NSF SBIR grant awarded to 'anu' for research and development on multispectral photomorphogenesis

Heliponix LLC, doing business as anu™ (previously gropod®), has been awarded a Phase II National Science Foundation Small Business Innovation Research (SBIR) grant for $970,993 and $75,000 in matching funding from Elevate Ventures.

31 Jan 2023

A high-throughput drug discovery assay for the endoplasmic reticulum aminopeptidase 1

The January 2023 issue of SLAS Discovery contains a collection of four full-length articles and one technical brief covering cancer research, high-throughput screening (HTS) assay development and other drug discovery exploration.

31 Jan 2023

Exploring how smoking cannabis alters the oral microbiome and its impact on the brain

Inspiration strikes when you least expect it. For Wei Jiang, M.D., a professor of Microbiology and Immunology at the Medical University of South Carolina (MUSC), inspiration came in 2018 on a smoke-filled boat tour around Amsterdam during an international conference.

30 Jan 2023

Newly discovered enzyme tells specific molecules precisely how to arrange themselves

Just as a choreographer's notation tells a dancer to strike a particular pose, an enzyme newly discovered by Rice University scientists is able to tell specific molecules precisely how to arrange themselves, down to the angle of single hydrogen bonds.

30 Jan 2023

Researchers create a tool to predict the effects of different diets on cancerous and healthy cells

A tool was developed by researchers to forecast the impact of various dietary plans on both cancerous and healthy cells.

30 Jan 2023

New center to assist in understanding non-coding cancer genome

The MacMillan Center for the Study of the Non-Coding Cancer Genome (MCSNCG) was officially launched by the New York Genome Center (NYGC) on January 18th, 2023.

19 Jan 2023

Taste trumps everything, despite some hesitation about gene-edited table grapes

Despite some hesitation about gene-edited foods, taste trumps everything, according to a Washington State University-led survey of U.S. consumers.

10 Jan 2023

First-ever chromosome-level genome sequences completed for sharks

The first chromosome level genome sequences for great hammerhead and shortfin mako sharks have shown that both species have experienced major population declines over a 250,000-year history.

5 Jan 2023

Octopuses' acuity may provide a critical link in understanding the evolution of complex life

Octopuses have captured the attention of scientists and the public with their remarkable intelligence, including the use of tools, engaging in creative play and problem-solving, and even escaping from aquariums.

16 Dec 2022

Researchers gain insights into how density may change gene expression in some insects

A grasshopper hatched in a crowded environment may look and behave differently than a grasshopper hatched in isolation -; even if they have the same genes.

14 Dec 2022

UConn researcher aims to fill knowledge gaps in the fight against invasive plants

Invasive species of plants have a knack for settling in new settings and making big changes to an ecosystem, even leading to extinctions of native species.

12 Dec 2022

UC San Diego Alpha Clinic awarded $8 million to bring new stem cell-based therapies to patients

Stem cells show particular promise in treating diseases for which few other effective treatments exist.

25 Nov 2022

Genetics and extensive schooling likely cause nearsightedness in children

Researchers have discovered five genetic variations that, the longer a person attends school, increase their risk of developing nearsightedness. These results were published on November 17th, 2022 in the open-access journal PLOS Genetics by a team at Cardiff University in the United Kingdom, led by Jeremy Guggenheim.

21 Nov 2022

Education News and Research

Study identifies genetic mutation in the SPTSSA gene as cause of Hereditary Spastic Paraplegia

Genomic study helps retrace origin and spread of Shigellosis outbreak in Seattle

Research supports the safety and efficacy of COVID-19 vaccination in cancer patients receiving immunotherapy

Study findings may pave way for personalized cancer treatment

Phase II NSF SBIR grant awarded to 'anu' for research and development on multispectral photomorphogenesis

A high-throughput drug discovery assay for the endoplasmic reticulum aminopeptidase 1

Exploring how smoking cannabis alters the oral microbiome and its impact on the brain

Newly discovered enzyme tells specific molecules precisely how to arrange themselves

Researchers create a tool to predict the effects of different diets on cancerous and healthy cells

New center to assist in understanding non-coding cancer genome

Taste trumps everything, despite some hesitation about gene-edited table grapes

First-ever chromosome-level genome sequences completed for sharks

Octopuses' acuity may provide a critical link in understanding the evolution of complex life

Researchers gain insights into how density may change gene expression in some insects

UConn researcher aims to fill knowledge gaps in the fight against invasive plants

UC San Diego Alpha Clinic awarded $8 million to bring new stem cell-based therapies to patients

Genetics and extensive schooling likely cause nearsightedness in children

Researchers develop a global indicator that measures the state of marine biodiversity

First-ever pedigree provides insights for maximizing genetic diversity in aquarium-bred corals

Treatment using CRISPR alleviates swelling attacks in hereditary angioedema patients

Genome Editing Has A New Code

Researchers reveal key developmental difference between the brains of modern humans and Neandertals

Cell Counting Without Slides to Reduce Waste and Cost

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