Genetic News and Research

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Study shows how whole genome sequencing test reveals details about cancer growth

Professor Serena Nik-Zainal of Cambridge University Hospitals (CUH) and the University of Cambridge headed a group of scientists that analyzed the whole genetic make-up or whole-genome sequencing (WGS) of over 12,000 NHS cancer patients in the largest research of its type.

22 Apr 2022

Study highlights an effective technique to overcome the rice yield constraint

Tradeoffs between diverse agronomic traits constrain crop breeding to a great extent. Because gene pleiotropy causes many of these tradeoffs, lowering gene pleiotropy may make it simpler to overcome tradeoffs in plant breeding.

22 Apr 2022

Researchers explore how tRNAs evolve in protein synthesis

In the process of protein synthesis, a peptide bond is formed between two amino acids that are bound to two different transfer RNAs (tRNAs). Researchers have long been perplexed as to how these tRNAs evolved to be so near to one another on the ribosome.

From Tokyo University of Science 22 Apr 2022

Little-known protein may play a role in frontotemporal lobar degeneration

Scientists have known for years that amyloid fibrils -; fibrous, ropelike structures formed by closely linked protein molecules -; are present in the brains of patients with Alzheimer's and Parkinson's diseases and likely play a role in the progression of these disorders.

21 Apr 2022

Alzheimer’s patients tend to have differed and increased genetic changes, says study

Errors present in DNA can get accumulated inside brain cells as one is aging. However, in patients with Alzheimer’s disease, these errors called somatic mutations may increase at a quicker rate.

21 Apr 2022

Researchers discover how new techniques may alter the synaptic connection of neurons

The brain has the potential to change the way neurons communicate with one another. That is how it prevents out-of-control brain activity. Scientists have discovered a mechanism that plays a key role in this.

21 Apr 2022

Researchers may have identified a key intermediate in the transition from prokaryotes to eukaryotes

All modern organisms fall into two classes, eukaryotes and prokaryotes. Eukaryotes (from the Greek meaning "true kernel") have a cell nucleus that harbors most of the cell's genetic information and includes organisms such as humans, plants and fungi.

20 Apr 2022

Research associates autophagy and age-related nervous system degradation

The in-built mechanism of recycling dead or poisonous material to preserve the health of human cells is critical to general health.

20 Apr 2022

Genomics provides a deeper understanding of the cause of hydrocephalus

The cerebral ventricles—four linked cavities of the brain that are packed with cerebrospinal fluid—become enlarged in hydrocephalus, or “water on the brain;” however, the cause is unknown in many instances.

20 Apr 2022

Scientists reveal the origins and provide a detailed ID card of pancreatic endocrine stem cells

The pancreas is a key metabolic regulator. When pancreatic beta cells cease producing enough insulin, blood sugar levels rise dangerously — a phenomenon known as hyperglycemia — thus triggering diabetes.

20 Apr 2022

Study provides a deeper understanding of how gene mutations contribute to breast cancer progression

A mutated gene found in more than 20% to 30% of breast cancer recurrences may help tumors become more aggressive and promote metastasis, according to a pair of new studies that uncover mechanisms behind these processes and point to new therapy targets.

From University of Pittsburgh 20 Apr 2022

Deeper understanding of genomics support researchers discover new perceptions

In genomic studies, researchers look at a population’s DNA to figure out how genetics affects health and disease.

20 Apr 2022

Rewiring the inner workings of leukemia cells to reverse drug resistance

Researchers from Barts Cancer Institute at Queen Mary University of London have identified a way to reverse resistance to a group of cancer drugs, known as kinase inhibitors, in leukemia cells.

20 Apr 2022

Scientists discover an effective drug development candidate from rare actinomycetes

Researchers are rushing to review a group of bacteria known as actinomycetes, which are one of the most successful sources of treatment.

19 Apr 2022

New research shows significant variations in B-cells in women with PPD

Jerry Guintivano, PhD, of the University of North Carolina School of Medicine, led an exclusive transcriptome-wide association research that showed substantial changes in B-cells in women with postpartum depression, with pathway observations indicating modified B-cell activation and insulin resistance.

19 Apr 2022

Genetic News and Research

Study shows how whole genome sequencing test reveals details about cancer growth

Study highlights an effective technique to overcome the rice yield constraint

Researchers explore how tRNAs evolve in protein synthesis

Little-known protein may play a role in frontotemporal lobar degeneration

Alzheimer’s patients tend to have differed and increased genetic changes, says study

Researchers discover how new techniques may alter the synaptic connection of neurons

Researchers may have identified a key intermediate in the transition from prokaryotes to eukaryotes

Research associates autophagy and age-related nervous system degradation

Genomics provides a deeper understanding of the cause of hydrocephalus

Scientists reveal the origins and provide a detailed ID card of pancreatic endocrine stem cells

Study provides a deeper understanding of how gene mutations contribute to breast cancer progression

Deeper understanding of genomics support researchers discover new perceptions

Rewiring the inner workings of leukemia cells to reverse drug resistance

Scientists discover an effective drug development candidate from rare actinomycetes

New research shows significant variations in B-cells in women with PPD

Researchers use CRISPR gene editing tool to analyze globin gene switching

Cryo-EM reveals the structure of fermentation enzyme phosphoketolase

A new breakthrough in the quest to improve photosynthesis in certain crops

Discovery could help break the cycle of rapid transmission of TB

Study shows how innate lymphoid cells may help to treat inflammatory bowel disease

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