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Researchers Discover How Deadly Hospital Pathogen can Survive Harsh Environments

The deadly hospital pathogen Acinetobacter baumannii can live for a year on a hospital wall without food and water. Then, when it infects a vulnerable patient, it resists antibiotics as well as the body's built-in infection-fighting response.

17 May 2023

Study Provides a New Picture of How Bacterial Cells Repair Faulty DNA

A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA.

17 May 2023

Study Finds Place of Transcription Start Often Determines the Place of Transcription End

Each gene in the human DNA has a start and an endpoint. It is critical to correctly define the gene's extremities to make functional proteins. Much study has been conducted to identify what determines when, where, and at which place on the DNA a gene “starts.”

16 May 2023

An In-Depth Analysis of the Human Genome Using the New “Pangenome”

The Human Genome Project, which began in April 2003, contributed to the revolutionization of biomedical research by giving researchers a reference map that allowed them to scan DNA sequences for genetic clues about the causes of a variety of diseases.

16 May 2023

Cell-to-Cell Genetic Module Exchange for Crop Evolution

According to a recent study conducted by researchers at New York University, comparing individual cells from corn, sorghum, and millet indicates discrepancies in these significant cereal crops’ evolutionary history.

From New York University (NYU) 16 May 2023

NIH Common Fund Selects New York Genome Center as Multi-Grant Recipient Under SMaHT Network

The National Institutes of Health (NIH) Common Fund has selected the New York Genome Center (NYGC) as a multi-grant recipient under the Somatic Mosaicism across Human Tissues (SMaHT) Network.

15 May 2023

New Probabilistic Model Unifies the Generation and Inference for Single-Cell, Spatial Omics Data

UCLA researchers have developed an "all-in-one," next-generation statistical simulator capable of assimilating a wide range of information to generate realistic synthetic data and provide a benchmarking tool for medical and biological researchers who use advanced technologies to study diseases and potential therapies.

12 May 2023

Study Demonstrates the First Molecular Link Between Circatidal and Circadian Clocks

Scientists at UMass Chan Medical School and the Marine Biological Laboratory at Woods Hole have identified the first gene-; Bmal1-; to play a crucial role in regulating circatidal behavior in the crustacean Parhyale hawaiensis.

12 May 2023

New Insights Into How Diverse Chromosomal Alterations Form and Drive Cancer Development

The goal of every dividing cell is to accurately segregate its genome into two genetically identical daughter cells.

12 May 2023

Chemical Modification Improves Non-Viral Gene Editing as Well as a New Type of DNA Repair

Gene editing is a powerful method for both research and therapy. Since the advent of the Nobel Prize-winning CRISPR/Cas9 technology, a quick and accurate tool for genome editing discovered in 2012, scientists have been working to explore its capabilities and boost its performance.

12 May 2023

Researchers Show a Second Key Gene Involved in Malaria's Resistance to Chloroquine

How malaria parasites evolved to evade a major antimalarial drug has long been thought to involve only one key gene.

12 May 2023

Prime Editing System Could Accelerate the Study of Cancer-Linked Mutations

Genomic studies of cancer patients have revealed thousands of mutations linked to tumor development.

12 May 2023

How the Natural Process of DNA Repair Fails to Cause Disease

We often come to an understanding of what causes a disease. We know, for example, that cancers are caused by mutations at critical locations in the genome, resulting in loss of control of cell growth.

11 May 2023

Researchers Use Cheese Rinds to Show Fungal Antibiotics Can Influence Microbiome Development

Fungi produce metabolites that humans have used to improve health. For example, they secrete penicillin, which is then purified and used as an antibiotic for humans, leading to the development of many other antibiotics.

11 May 2023

Genetic Material Inherited from Neanderthals Influences the Shape of Our Noses

Humans inherited genetic material from Neanderthals that affects the shape of our noses, finds a new study led by UCL researchers.

9 May 2023

STING-seq Discovers Causal Variants and Genetic Mechanisms for Blood Cell Traits

A major challenge in human genetics is understanding which parts of the genome drive specific traits or contribute to disease risk. This challenge is even greater for genetic variants found in the 98% of the genome that does not encode proteins.

5 May 2023

Innate Tumor Suppression Mechanism Uncovered

The p53 gene is one of the most important in the human genome: the only role of the p53 protein that this gene encodes is to sense when a tumor is forming and to kill it.

5 May 2023

Understanding How Supernumerary Chromosomes Arise

The majority of chromosomes have existed for millions of years.

5 May 2023

Study Uncovers Cancer-Like Changes in Mitochondrial Disease of Newborns

A study found that a mitochondrial disease of newborns shows cancer-like changes in proliferating cells, causing tissues to age prematurely.

4 May 2023

Researchers Map GCK Gene Variants to Better Diagnose Hereditary Diseases

Researchers at the Department of Biology, University of Copenhagen, have now contributed to solving this problem for a specific gene called GCK. The study has just been published in Genome Biology.

4 May 2023

Genome News and Research

Researchers Discover How Deadly Hospital Pathogen can Survive Harsh Environments

Study Provides a New Picture of How Bacterial Cells Repair Faulty DNA

Study Finds Place of Transcription Start Often Determines the Place of Transcription End

An In-Depth Analysis of the Human Genome Using the New “Pangenome”

Cell-to-Cell Genetic Module Exchange for Crop Evolution

NIH Common Fund Selects New York Genome Center as Multi-Grant Recipient Under SMaHT Network

New Probabilistic Model Unifies the Generation and Inference for Single-Cell, Spatial Omics Data

Study Demonstrates the First Molecular Link Between Circatidal and Circadian Clocks

New Insights Into How Diverse Chromosomal Alterations Form and Drive Cancer Development

Chemical Modification Improves Non-Viral Gene Editing as Well as a New Type of DNA Repair

Researchers Show a Second Key Gene Involved in Malaria's Resistance to Chloroquine

Prime Editing System Could Accelerate the Study of Cancer-Linked Mutations

How the Natural Process of DNA Repair Fails to Cause Disease

Researchers Use Cheese Rinds to Show Fungal Antibiotics Can Influence Microbiome Development

Genetic Material Inherited from Neanderthals Influences the Shape of Our Noses

STING-seq Discovers Causal Variants and Genetic Mechanisms for Blood Cell Traits

Innate Tumor Suppression Mechanism Uncovered

Understanding How Supernumerary Chromosomes Arise

Study Uncovers Cancer-Like Changes in Mitochondrial Disease of Newborns

Researchers Map GCK Gene Variants to Better Diagnose Hereditary Diseases

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