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Scientists use molecular dynamics simulations to reveal the secrets of SARS-CoV-2 virus

The virus wreaking havoc on our lives is an efficient infection machine. Comprised of only 29 proteins (compared to our 400,000), with a genome 1/200,000 the size of ours, SARS-CoV-2 is expertly evolved to trick our cells to contribute its machinery to assist in its propagation.

22 Oct 2020

Ancient embedded elements in human DNA can activate powerful immune response to kill cancer cells

Ancient embedded elements in our DNA from generations past can activate a powerful immune response to kill cancer cells like an infection.

22 Oct 2020

New research indicates the link between diabetes and SARS-CoV-2 viral infection

Recently, researchers explained that infection by certain enteroviruses could possibly activate diabetes.

22 Oct 2020

New DNA-cutting tool could advance gene editing for novel treatments

Gene editing for the development of new treatments, and for studying disease as well as normal function in humans and other organisms, may advance more quickly with a new tool for cutting larger pieces of DNA out of a cell's genome, according to a new study by UC San Francisco scientists.

21 Oct 2020

Study explores the impact of microbial immune diversity on dynamics of host-virus interactions

CRISPR-Cas serves as a key driving force of strain diversity in host-virus systems during an evolutionary fight between the host and virus.

21 Oct 2020

First-ever draft sequence of the human proteome mapped successfully

Two decades after the release of the human genome, researchers have mapped the first-ever draft sequence of the human proteome.

21 Oct 2020

Researchers develop new method to advance wildlife genomics

A team of scientists from the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW), the Australian Museum, and the Max Delbrück Center for Molecular Medicine (MDC) report a new method for identifying any genome sequence located next to a known sequence.

20 Oct 2020

Researchers identify “silent” mutations in the genetic code of COVID-19 virus

We know that the coronavirus behind the COVID-19 crisis lived harmlessly in bats and other wildlife before it jumped the species barrier and spilled over to humans.

19 Oct 2020

CRISPR platform can accelerate potential treatment targets for SARS-CoV-2

Synthego has provided multiple CRISPR-based engineered cell lines to speed up the analysis of promising treatment targets for SARS-CoV-2.

19 Oct 2020

Researchers identify potential drugs that could be repurposed as pan-coronavirus treatments

A large international consortium of almost 200 researchers from 14 leading institutions in six countries has studied three different coronaviruses - SARS-CoV-1, SARS-CoV-2, and MERS-CoV - with the aim of finding vulnerabilities shared by these three pathogens.

16 Oct 2020

Study sheds light on whether corals are genetically equipped to handle warmer oceans

In 1998, ocean temperatures soared, and the world experienced its first significant coral bleaching event. From the Great Barrier Reef to Indonesia to Central America, corals turned white and ghostly.

15 Oct 2020

DNA structural changes play key role in the recovery phase after DNA damage

A research team from Cologne has discovered that a change in the DNA structure - more precisely in the chromatin - plays a decisive role in the recovery phase after DNA damage. The key is a double occupation by two methyl groups on the DNA packaging protein histone H3 (H3K4me2).

15 Oct 2020

Novel mechanism restores cell function after DNA damage

Scientists have found that a modification in the DNA structure— specifically in the chromatin—plays a key role in the recovery stage following DNA damage.

15 Oct 2020

Scientists discover key parameters to better predict cancer-killing effect of neoantigens

Neoantigens, tiny markers that arise from cancer mutations, flag cells as cancerous and could be the key to unlocking a new generation of immunotherapies.

14 Oct 2020

VAV1 gene mutations may promote growth of T-cell tumors in laboratory mice

Life is an exquisite orchestration of growth and change, with checks and balances that fine-tune complex entwined interactions, both intrinsic and external.

13 Oct 2020

Researchers identify mechanism that silences “parasitic” DNA-elements in pluripotent stem cells

Every eukaryotic organism contains the so-called transposons, which are abundant DNA-elements.

13 Oct 2020

Scientists discern molecular mechanisms underlying plant parasitism and cross-species grafting

Using the model Orobanchaceae parasitic plant Phtheirospermum japonicum, scientists from Nagoya University and other research institutes from Japan have discerned the molecular mechanisms underlying plant parasitism and cross-species grafting, pinpointing enzyme β-1,4-glucanase (GH9B3) as an important contributor to both phenomena.

12 Oct 2020

Scientists develop UK Crop Microbiome Cyrobank to facilitate sustainable yield improvement

Scientists from the UK's foremost agricultural research institutes have teamed up to create a new UK Crop Microbiome Cyrobank (UK-CMCB) to safeguard future research and facilitate the sustainable yield improvement of the UK's six major food crops including barley, oats, oil seed rape, potato, sugar beet and wheat.

12 Oct 2020

Genomes provide insights into fig-wasp coevolution

Banyan trees are fig trees that begin their life as an epiphyte. The most noticeable feature of banyan Ficus species is their extraordinary aerial roots, which enable them to live as hemi-epiphytes, as do the strangler figs often seen in tropical forests.

12 Oct 2020

UroCAD assay shows better sensitivity than urine cytology in detecting bladder cancer

Analysis of DNA copy number variants (CNVs) in the cells exfoliated in urine showed better sensitivity and similar specificity in detecting urothelial carcinoma compared with urine cytology.

12 Oct 2020

Genome News and Research

Scientists use molecular dynamics simulations to reveal the secrets of SARS-CoV-2 virus

Ancient embedded elements in human DNA can activate powerful immune response to kill cancer cells

New research indicates the link between diabetes and SARS-CoV-2 viral infection

New DNA-cutting tool could advance gene editing for novel treatments

Study explores the impact of microbial immune diversity on dynamics of host-virus interactions

First-ever draft sequence of the human proteome mapped successfully

Researchers develop new method to advance wildlife genomics

Researchers identify “silent” mutations in the genetic code of COVID-19 virus

CRISPR platform can accelerate potential treatment targets for SARS-CoV-2

Researchers identify potential drugs that could be repurposed as pan-coronavirus treatments

Study sheds light on whether corals are genetically equipped to handle warmer oceans

DNA structural changes play key role in the recovery phase after DNA damage

Novel mechanism restores cell function after DNA damage

Scientists discover key parameters to better predict cancer-killing effect of neoantigens

VAV1 gene mutations may promote growth of T-cell tumors in laboratory mice

Researchers identify mechanism that silences “parasitic” DNA-elements in pluripotent stem cells

Scientists discern molecular mechanisms underlying plant parasitism and cross-species grafting

Scientists develop UK Crop Microbiome Cyrobank to facilitate sustainable yield improvement

Genomes provide insights into fig-wasp coevolution

UroCAD assay shows better sensitivity than urine cytology in detecting bladder cancer

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